Vaginal fluid and serum CEA, CA125 and SCC in normal conditions and in benign and malignant diseases of the genital tract

Acta Oncologica

Volumn 36, Issue 7, 1997, Pages 755-759

  Sarandakou, Angeliki ^a   Phocas, Iphigenia ^a   Botsis, Demetrios ^a   Rizos, Demetrios ^a   Trakakis, Eftichios ^a   Chryssikopoulos, Athanassios ^a  

^a UNIVERSITY OF ATHENS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

CA 125 ANTIGEN; CARCINOEMBRYONIC ANTIGEN;

ADULT; AGED; ARTICLE; BLOOD LEVEL; DIAGNOSTIC VALUE; FEMALE; GENITAL TRACT CANCER; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; PREGNANCY; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; VAGINA DISCHARGE;

EID: 0031407141     PISSN: 0284186X     EISSN: None     Source Type: Journal    
DOI: 10.3109/02841869709001350     Document Type: Article

References (28)

1. Tholander B, Toube A, Lindgren A, et al. Pretreatment serum levels of CA-125, carcinoembryonic antigen, tissue polypeptide antigen, and placental alkaline phosphatase, in patients with ovarian carcinoma, borderline tumors, or benign adnexal masses: relevance for differential diagnosis. Gynecol Oncol 1990; 39: 16-25.
2. Werlooy H, Devos P, Janssens J, et al. Clinical significance of squamous cell carcinoma antigen in cancer of the human uterine cervix. Comparison with CEA and CA-125. Gynecol Obstet Invest 1991; 32: 55-8.
3. Leminen A. Tumor markers CA125, carcinoembryonic antigen and tumor-associated trypsin inhibitor in patients with cervical adenocarcinoma. Gynecol Oncol 1990; 39: 358-63.
4. Kabawat SE, Bast RV, Welch WR, Knapp RC, Colvin RB. Immunopathologic characterization of a monoclonal antibody that recognises common surface antigens of human ovarian tumors of serous, endometrioid and clear cell types. Am J Clin Path 1983; 79: 98-104.
5. Fujii S, Konishi I, Nambu Y, Nonogaki H, Kobayashi F, Sagawa N, Mori T, Endo K. Analysis of the levels of CA125, carcinoembryonic antigen, and CA19-9 in the cervical mucus for a detection of cervical adenocarcinoma. Cancer 1988; 62: 541-7.
6. Kearsly J, Stenzel D, Scully T, Cooke R. Cellular localization of tumor antigen (TA-4) in normal dysplastic and neoplastic squamous epithelia of the upper aerodigestive tract. Br J Cancer 1990; 61: 631-5.
7. Harlozinska A, Kula J, Stepinska B, Jelen M, Richter R, Slesak B. Cervical carcinoma antigen, carcinoembryonic antigen (CEA), and nonspecific cross-reacting anligcn (NCA) in appraisal of uterine cervix smears. Am J Clin Pathol 1985; 83: 301-7.
8. Fleuren GJ, Nap M, Aalders JG, Trimbos JB, de Bruijn HWA. Explanation of the limited correlation between tumor CA125 content and serum CA125 antigen levels in patients with ovarian tumors. Cancer 1987; 60: 2437-42.
9. de Bruijn HWA, van Beeck Calkoen-Carpay T, Jager S, Duk JM, Aalders JG, Fleuren GJ. The tumor marker CA125 is a constituent of normal cervical mucus. Am J Obstet Gynecol 1986; 154: 1088-91.
10. Haga V, Sakamoto K, Egani H, Yoshimura R, Akagi M. Evaluation of serum CA125 values in healthy individuals and pregnant women. Am J Med Sci 1986; 292: 25-9.
11. Crombach G, Scharl A, Vierbuchen M, Würz H, Bolte A. Detection of squamous cell carcinoma antigen in normal squamous epithelia and in squamous cell carcinoma of the uterine cervix. Cancer 1989; 63: 1337-42.
12. Benagiano G, Thomas EJ. Benign proliferative disorders of the female tract: a call for a special interest group. Human Reproduction 1992; 3: 291-2.
13. Jacobs I, Bast RC. The CA125 tumour-associated antigen: a review of the literature. Human Reprod 1989; 4: 1-12.
14. O'Brien JJ, Hardin JW, Bannon GA, Norris JS, Quirk G. CA125 antigen in human amniotic fluid and fetal membranes. Obstet Gynecol 1986; 155: 50-5.
15. Lelle RJ, Henkel E, Leinemann D, Goeschen K. Measurement of CEA. TPA, Neopterin, CA125, CA153 and CA19-9 in sera of pregnant women, umbilical cord blood and amniotic fluid. Ciynecol Obstet Invest 1989; 27: 137-42.
16. Sarandakou A, Kontoravdis A, Kontogeorgi Z, Rizos D, Phocas I. Expression of CEA, CA125 and SCC antigens in biological fluids associated with pregnancy. Eur J Obstet Gynecol Reprod Biol 1992; 44: 215-20.
17. Takeshima N, Suminami Y, Takeda O, Abe H, Kato H. Origin of CA125 and SCC antigen in amniotic fluid. Asia Oceania J Obstet Gynaecol 1993; 19: 199-204.
18. Abae M, Gibson M, Chapitis J, Riddick DH, Brumsted JR. CA-125 levels in human uterine fluid. Fertil Steril 1992; 57: 531-4.
19. von Briese V, Barten G, Strache RR, Büttner HH, Voss P. Nachweis des carcinoembryonalen antigen (CEA) in zervikovaginalspulflussigkeiten. Zent Bl Gynekol 1989; 111: 223-9.
20. Jimera P, Castilla JA, Ramirez JP, Gil T, Acebal M, Molina R, Herruzo A. Follicular fluid α-fetoprotein, carcinoembryonic antigen and CA-125 levels in relation to in vitro fertilization and gonadotropin and steroid hormone concentrations. Fertil Steril 1993; 59: 1257-60.
21. Phocas I, Sarandakou A, Rizos D, Dimitriadou F, Mantzavinos Th, Zourlas PA. Tumour-associated antigen CEA, CA125 and SCC in serum and follicular fluid of stimulated and unstimulated cycles. Eur J Obstet Gynecol Reprod Biol 1994; 54; 1131-8.
22. Campbell B, De Ambrosis B. Squamous cell carcinoma antigen in patients with cutaneous disorders. J Am Acad Dermatol 1990; 22: 639-42.
23. Zeimet AG, Muller-Holzner E, Marth CR, Daxenbichler G, Dapunt O. Tumor marker CA125 in tissues of the female reproductive tract and in serum during the normal menstrual cycle. Fertil Steril 1993; 59: 1028-35.
24. Halila H, Huhtala ML, Haglund C, Nordling S, Stenman UH. Tumour associated trypsin inhibitor (TAT1) in human ovarian cyst fluid. Comparison with CA 125 and CEA. Br J Canter 1987; 56: 153-6.
25. Duk JM, de Bruijn HWA, Groenier KH, et al. Cancer of the uterine cervix: Sensitivity and specificity of serum squamous cell carcinoma antigen determinations. Gynecol Oncol 1990; 39: 186-94.
26. Hoshina M, Kimura A, Shibata K, Maruo T, Moshizuki M. Immunocytological distribution of the tumor antigen TA-4: Expression during carcinogenesis and maturation of squamous epithelium of human uterine cervix. Asia Oceania J Obstet Gynecol 1986; 12: 119-26.
27. Lehtovirta P, Vinika L, Ylikorkala O. Comparison between squamous cell carcinoma-associated antigen and CA125 in patients with carcinoma of the cervix. Gynecol Oncol 1990; 37: 276-8.
28. Barbati A, Ancechi MM, Alberti P, Pomili G, Di Renzo GC, Cosmi EV. Ontogeny of CA125 antigen in pregnancy: Immunohistochemical localization in fetal membranes. Am J Obstet Gynecol 1989; 160: 514-7.