Determination of the active metabolite of prulifloxacin in human plasma by HPLC with fluorescence detection

Chromatographia

Volumn 66, Issue 1-2, 2007, Pages 37-41

  Wen, Jun ^a,b   Zhu, Zhenyu ^a,b   Hong, Zhanying ^a,b   Wu, Yiwen ^a,b   Fei, Yan ^a,b   Lin, Mei ^c   Fan, Guorong ^a,b   Wu, Yutian ^a,b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI KEY LABORATORY FOR PHARMACEUTICAL METABOLITE RESEARCH   (China)

^c SHANGHAI INSTITUTE FOR FOOD AND DRUG CONTROL   (China)

Author keywords

Column liquid chromatography; Fluorescence detection; Pharmacokinetics; Prulifloxacin; Ulifloxacin

Indexed keywords

ACETONITRILE; ANTIBIOTIC AGENT; DRUG METABOLITE; LEMEFLOXACIN; PERCHLORIC ACID; PRULIFLOXACIN; TRIETHYLAMINE; ULIFLOXACIN; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; FLUORESCENCE; FLUORESCENCE ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; PRECIPITATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STANDARD; TEMPERATURE;

EID: 34447109394     PISSN: 00095893     EISSN: 16121112     Source Type: Journal    
DOI: 10.1365/s10337-007-0256-0     Document Type: Article

References (8)

1. Keam SJ, Perry CM (2004) Drugs 64:2221-2234
2. Matera MG (2006) Pulm Pharmacol Ther 19:20-29
3. Tougou K, Nakamura A, Watanabe S, Okuyama Y, Morino A (1998) Drug Metab Dispos 26:355-359
4. Nakashima M, Uematsu T, Kosuge K, Okuhama Y, Morino A, Ozaki M, Takebe Y (1994) J Clin Pharmacol 34:930-937
5. Picollo R, Brion N, Gualano V, Millerioux L, Marchetti M, Rosignoli MT, Dionisio P (2003) Arzneim-Forsch 53:201-205
6. Guo L, Qi M, Jin X, Wang P, Zhao H (2006) J Chromatogr B 832:280-285
7. Fen YF, Li KX, Xie F, Sun CH (2006) Chin J Pharm Anal 26:755-758
8. USFDA (2001) http://www.fda.gov/cder/guidance/4252fnl.htm