Crystal Structure of the Parasite Protease Inhibitor Chagasin in Complex with a Host Target Cysteine Protease

Journal of Molecular Biology

Volumn 371, Issue 1, 2007, Pages 137-153

  Ljunggren, Anna ^a   Redzynia, Izabela ^b   Alvarez Fernandez, Marcia ^a   Abrahamson, Magnus ^a   Mort, John S ^c   Krupa, Joanne C ^c   Jaskolski, Mariusz ^d,e   Bujacz, Grzegorz ^b,e  

^a LUND UNIVERSITY   (Sweden)

^b LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

^c SHRINERS HOSPITAL FOR CHILDREN   (Canada)

^d ADAM MICKIEWICZ UNIVERSITY   (Poland)

^e POLISH ACADEMY OF SCIENCES   (Poland)

Author keywords

Chagas' disease; cysteine peptidases; cysteine proteinases; lysosomal enzymes; Trypanosoma cruzi

Indexed keywords

CATHEPSIN L; CHAGASIN; CRUZIPAIN; CYSTATIN; CYSTEINE PROTEINASE; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CATALYSIS; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CRYSTALLIZATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; HOST RESISTANCE; MOLECULAR INTERACTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; STRUCTURE ANALYSIS;

TRYPANOSOMA CRUZI;

EID: 34447101224     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.05.005     Document Type: Article

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