A study on the interaction between p60c-Src receptor tyrosine kinase and arylcarboxylic and arylacetic acid derivatives based on docking modes and in vitro activity

Biological and Pharmaceutical Bulletin

Volumn 27, Issue 1, 2004, Pages 61-65

  Altuntas, Tunca Gul ^a   Olgen, Sureyya ^a   Nebioglu, Dogu ^a   Akaho, Eiichi ^b  

^a ANKARA UNIVERSITY   (Turkey)

^b KOBE GAKUIN UNIVERSITY   (Japan)

Author keywords

Arylacetic acid; Arylcarboxylic acid; Molecular docking; Tyrosine kinase

Indexed keywords

ACETIC ACID DERIVATIVE; AMIDE; CARBOXYLIC ACID DERIVATIVE; LYSINE DERIVATIVE; PROTEIN KINASE P60; PROTEIN TYROSINE KINASE; CARBOXYLIC ACID; ENZYME INHIBITOR;

ARTICLE; COMPARATIVE STUDY; DRUG ACTIVITY; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME SUBSTRATE; STRUCTURE ACTIVITY RELATION; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HYDROGEN BOND; METABOLISM;

ACETIC ACIDS; BINDING SITES; CARBOXYLIC ACIDS; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR CONFORMATION; ONCOGENE PROTEIN PP60(V-SRC);

EID: 3442902536     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.27.61     Document Type: Article

References (19)

1. Terrence R. B., Drugs of the Future, 17, 119-131 (1992).
2. Traxler P., Lydon N., Drugs of the Future, 20, 1261-1274 (1995).
3. Roussidis A. E., Karamanos N. K., In Vivo, 16, 459-470 (2002).
4. Klohs W. D., Fry D. W., Kraker A. J., Curr. Opin. Oncol., 9, 562-568 (1997).
5. Levitzki A., Gazit A., Science, 267, 1782-1788 (1995).
6. Traxler P., Furet P., Mett H., Buchdunger E., Meyer T., Lydon N., J. Pharm. Belg., 52, 88-96 (1997).
7. Hamby J. M., Showalter H. D. H., Pharmacol. Ther., 82, 169-193 (1999).
8. Fabbro D., Parkinson D., Matter A., Curr. Opin. Pharmacol., 2, 374-381 (2002).
9. Kenyon K. L., Garcia G. A., Med. Res. Rev., 7, 389-416 (1987).
10. Larson E. R., Fischer PH., "Annual Reports in Medicinal Chemistry," Vol. 24, ed. by Allen R. C., Academic Press Inc., San Diego, 1989, pp. 125-126.
11. Johnson R. J., Hertzberg R. P., "Annual Reports in Medicinal Chemistry," Vol. 25, ed. by Bristol J. A., Academic Press Inc., San Diego, 1990, pp. 136-143.
12. Ewing T. J. A., DOCK4.0 User Manual, University of California, San Francisco: 〈http://www.cmpharm.ucsf.edu/kuntz/dock.html〉, 1998.
13. Taylor V. C., Buckley C. D., Douglas M., Cody A. J., Simmons D. L., Freeman S. D., J. Biol. Chem., 274, 11505-11512 (1999).
14. Kuntz I. D., Blaney J. M., Oatley S. J., Langridge R., Ferrin T. E., J. Mol. Biol., 161, 269-288 (1982).
15. Nebioglu D., Altuntas T. G., Goker H., J. Fac. Pharm. Gazi, 10, 69-81 (1993).
16. Ewing T. J. A., Makino S., Skillman A. G., Kuntz I. D., J. Comput.-Aid. Mol. Des., 15, 411-428 (2001).
17. Taylor R. D., Jewsbury P. J., Essex J. W., J. Comp.-Aid. Mol. Des., 16, 151-166 (2002).
18. Illapakurthy A. C., Sabnis Y. A., Avery B. A., Avery M. A., Wyandt C. M., J. Pharm. Sci., 92, 649-655 (2003).
19. Hanke J. H., Gardner J. P., Dow R. L., Changelian P. S., Brissette W. H., Weringer E. J., Pollok B. A., Connelly P. A., J. Biol. Chem., 271, 695-701 (1996).