Role of cholesteryl ester transfer protein activity and genetic polymorphism in ischemic heart disease in type 2 diabetic patients;Rôle de l'activité et du polymorphisme génétique de la protéine de transfert des esters de cholestérol (CETP) dans les cardiopathies ischémiques chez les diabetiques type 2

Tunisie Medicale

Volumn 82, Issue 3, 2004, Pages 282-288

  Chaaba, Raja ^a   Smaoui, Maha ^a   Hammami, Sonia ^c   Attia, Nebil ^a   Ben Kholdoun, Hamda ^b,d   Masmoudi, Ahmed Slaheddine ^a   Mahjoub, Sylvia ^c   Bouslama, Ali ^e   Ben Farhat, Mohamed ^b,d   Girard Globa, Annick ^f   Hammami, Mohamed ^c  

^a Laboratoire de Biochimie

^b 9 Faculte de Medecine de Monastir   (Tunisia)

^c Service de Médecine Interne

^d Service de Cardiologie EPS Monastir   (Tunisia)

^e Laboratoire de Biochimie   (Tunisia)

^f Hôpital de Cardiologie Lyon   (France)

Author keywords

CETP; HDL C; Ischemic heart disease; Taq IB; Type 2 diabetes

Indexed keywords

CHOLESTEROL ESTER; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN; TAQ IB POLYMERASE; TAQ POLYMERASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADULT; ALLELE; ARTICLE; CARDIOVASCULAR RISK; CAUCASIAN; CETP GENE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FEMALE; GENE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; ISCHEMIC HEART DISEASE; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; AGED; ALLELES; BLOOD GLUCOSE; CARRIER PROTEINS; CHOLESTEROL ESTER TRANSFER PROTEINS; CHOLESTEROL ESTERS; CHOLESTEROL, HDL; CORONARY ANGIOGRAPHY; CORONARY DISEASE; DATA INTERPRETATION, STATISTICAL; DIABETES MELLITUS, TYPE 2; FEMALE; GENOTYPE; GLYCOPROTEINS; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RISK FACTORS; TRIGLYCERIDES;

EID: 3442897623     PISSN: 00414131     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Barbara V.H, David C.R, Maurice L.S, Elisa T.L, Dorthy R, Richard B.D, Linda D.C, Stuart G, Thomas K.W, Oscar T.G, James H. LDL cholesterol as a strong predictor of coronary heart disease in diabetic individuals with insulin resistance and low LDL The Strong Heart Study Arterioscler. Thromb. Vasc Biol 2000; 20: 830-5.
2. Robert A, K Diabetic Dyslipidemia Am J Cardiol 1998; 82: 67U-73U.
3. Richard E, Morton D, Zilversmit B. Purification and characterization of lipid transfer protein(s) from human lipoprotein deficient plasma. J. Lipid Res 1982; 23: 1058-1067.
4. Luis B. Agellon E.M, Quinet T, Gillette G, Dennis Drayana T, Maryanne Brown L, Tall A.R. Organization of the human cholesteryl ester transfer protein gene. Biochemistry 1990; 29: 1372-1376.
5. Fumeron F, Betoulle D, Luc G, Behague I, Ricard S, Poirier O, Jemaa R, Evans A, Arveiler D Marques Vidal P, Bard JM, Fruchard JC, Ducimetière P, Apfelbaum M, Cambien F. Alcohol intake modulates the effect of a polymorphism of the cholesteryl ester transfer protein gene on plasma high density lipoprotein and the risk of myocardial infraction. J. Clin Invest 1995; 96: 1664-1697.
6. Study Group, European Atherosclerosis Society Strategies for the prevention of coronary heart disease: A policy statement of the European Atheroslerosis Society European Heart Journal 1987; 8: 77-88.
7. Burstein M, Scholnick HR, Morphin R. Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions J. of Lipid Resarch 1970; 11: 583-95.
8. Slimane N, Hammami M et Ben Farhat M. Méthodes de dosage des apolipoprotéines Essaydali 1992; 44: 21-25.
9. Tall A, Granot E, Brocia R, Tabas I, Hesler C, Williams K, Denke M. Accelerated transfer of cholesteryl ester in dyslipidemic plasma. Role of cholesteryl ester transfer protein J. Clin. Invest 1987; 79: 1217-1225.
10. Atger V, Wirbel E, Roche D, Apfelbaum M, Burstein M, B, Girard-Globa A. Distribution of HDL2 and HDL3 in a random population of healthy French males and females - evaluation by a two-step precipitation procedure Clinica Chimica Acta 1990; 189: 111-122.
11. Gordon D.J, Probstfield J.L, Garrison R.J, Neaton JD, Jacob DR Jr, Bangdiwala S, Tyroler HA. High-density lipoprotein Cholesterol and Cardiovascular disease: Four prospective American Studies. Circulation 1989; 79: 8-15.
12. Bagdade JD, Lane JT, Subbaiah PV, Otto ME, Ritter MC Accelerated cholestryl ester transfer in noninsulin-dependent diabetes mellitus Atherosclerosis 1993; 104: 69-77.
13. Lagrost L. Regulation of cholesteryl ester transfer protein (CETP) activity; review of in vitro and in vivo studies. Biochimica et Biophysica Acta 1994; 1215: 209-236.
14. Martin U, Connely PW, Nancoo D Chalesteryl ester transfer protein and high density lipoprotein response to cholesterol feeding in men relationship to Apo E genotype J Lipid Res 1993; 34: 437-46.
15. Moulin Ph. La protéine de transfert du chalestérol estérifié (CETP) Sang thrombose vaisseaux 1995; 7: 475-85.
16. Federico T, Gloria L.V, Alan R.T, Scatt M.G Relation between cholesterol ester transfer protein activities and lipoprotein cholesterol in patients with hypercholesterolemia and combined hyperlipidemia. Arterioscler. Thromb. Vasc. Biol 1995; 15: 112-120.
17. Bernard S, Moulin P, Lagrost L, Picard S, Elchebly M, Ponsin G, Chapuis F, and Berthezène F. Association between plasma C-HDL concentration and TaqIB CETP gene polymorphism in non-insulin dependent diabetes mellitus J. lipid research 1998; 39: 10-20.
18. Kark J.D, Sinnreich R, Leitersdorf E, Friedlander Y, Shpitzen S, Lue G Taq IB polymorphism, plasma CETP, lipoproteins, apolipoproteins and sex differences in a Jewish population sample characterised by low HDL-cholesterol Atherosclerosis 2000; 151: 509-518.
19. Dachet Ch, Poirier O, Cambien F, Chapman J, Rouis M New functional promoter polymorphism, CETP/-629, in cholesteryl ester transfer protein (CETP) gene related to CETP mass and high density lipoprotein cholesterol level Role of Sp1/Sp3 in transcriptional regulation Arterioscler. Thramb. Vasc. Biol 2000; 20: 507-515.
20. Ordovas J M, Cupples LA, Correla D, Otvos JD, Osgood D, Martine A, Lahoz C, Coltell O, Wilson PW, Schaefer EJ. Association of CETP TaqIB polymorphism with variations in lipoprotein subclasses and Coronary heart disease risk: the Framingham study. Arterioscler Thromb Vasc. Biol 2000; 20.
21. Toury I, Zahouani A, Husson M, Schellenberg F, Fumeron F, Betoulle D, Vacher D, Lamisse F, Girard-Globa A. Variability of the gene coding for cholesteryl ester transfer protein influences the response of transfer activity and HDL-cholesterol to alcohol. Nutr. Metab. Cardiovasc. Dis 1998; 8: 185-191.
22. Anne Durlach, Christine Clavel, Anik Girard-Globa, Vincent Durlach Sex-dependent association of a genetic polymorphism of cholesteryl ester protein with high-density lipoprotein cholesterol and macrovascular pathology in type II diabetic patients The journal of clinical endocrinology and metabolism 1999; 84: 3656-3659.
23. Jan AK, J. Wouter J, Aeilkoh Z, Peter K, Ruth Mc Ph, Albert VG.B, Kong I.L, John J.P.K The role of a common variant of the CETP gene in the progression of coronary atherosclerosis The New England Journal of Medecine 1998; 338-2.