Penetrating limbo-keratoplasty for granular and lattice corneal dystrophy: Survival of donor limbal stem cells and intermediate-term clinical results

Ophthalmology

Volumn 111, Issue 8, 2004, Pages 1528-1533

  Spelsberg, Helga ^a   Reinhard, Thomas ^b   Henke, Lotte ^c   Berschick, Peter ^d   Sundmacher, Rainer ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c Institut fur Blutgruppenforschung   (Germany)

^d Landeskriminalamt N Rhine Westfalia   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOSUPPRESSIVE AGENT; PREDNISONE ACETATE; DRUG DERIVATIVE; PREDNISOLONE; PREDNISOLONE ACETATE;

ADULT; AGED; ARTICLE; CHEEK MUCOSA; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORNEA DYSTROPHY; CORNEA TRANSPLANTATION; CORRELATION ANALYSIS; EPITHELIUM CELL; EVALUATION; FOLLOW UP; GENETIC ANALYSIS; HUMAN; KERATOPLASTY; LIMB; POLYMERASE CHAIN REACTION; POSTOPERATIVE CARE; PRIORITY JOURNAL; PROPHYLAXIS; RECURRENT DISEASE; SAMPLE; SHORT TANDEM REPEAT; STATISTICAL SIGNIFICANCE; STEM CELL; TIME SERIES ANALYSIS; ADOLESCENT; CELL SURVIVAL; CONGENITAL CORNEA DYSTROPHY; CONJUNCTIVA; CORNEA EPITHELIUM; CORNEA LIMBUS; CYTOLOGY; DNA FINGERPRINTING; DONOR; DRUG EFFECT; EPITHELIUM; GENETICS; GRAFT SURVIVAL; METHODOLOGY; MIDDLE AGED; PENETRATING KERATOPLASTY; PHYSIOLOGY; PROSPECTIVE STUDY; RETROSPECTIVE STUDY; STEM CELL TRANSPLANTATION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CELL SURVIVAL; CONJUNCTIVA; CORNEAL DYSTROPHIES, HEREDITARY; DNA FINGERPRINTING; EPITHELIUM; EPITHELIUM, CORNEAL; FOLLOW-UP STUDIES; GRAFT SURVIVAL; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KERATOPLASTY, PENETRATING; LIMBUS CORNEAE; MIDDLE AGED; POLYMERASE CHAIN REACTION; PREDNISOLONE; PROSPECTIVE STUDIES; RECURRENCE; RETROSPECTIVE STUDIES; STEM CELL TRANSPLANTATION; STEM CELLS; TISSUE DONORS;

EID: 3442891481     PISSN: 01616420     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ophtha.2004.01.030     Document Type: Article

References (30)

1. Witschel H., Sundmacher R. Bilateral recurrence of granular corneal dystrophy in the grafts. A clinico-pathologic study. Graefes Arch Klin Exp Ophthalmol. 209:1979;179-188
2. Auw-Häedrich C., Loeffler K.U., Sundmacher R., Witschel H. Characteristic distribution of deposits in recurrent granular corneal dystrophy. Ger J Ophthalmol. 5:1996;132-136
3. Small K.W., Mullen L., Barletta J., et al. Mapping of Reis-Bücklers' corneal dystrophy to chromosome 5q. Am J Ophthalmol. 121:1996;384-390
4. Bron A.J. Genetics of the corneal dystrophies what we have learned in the past twenty-five years. Cornea. 19:2000;699-711
5. Auw-Hädrich C., Witschel H. Hornhautdystrophien im Licht moderner molekulargenetischer Forschung. Ophthalmologe. 99:2002;418-426. [Corneal dystrophies in the light of modern molecular genetic research]
6. Munier F.L., Schorderet D.F. Chromosome 5q31 linked corneal dystrophies outline for a new classification. [in German] Klin Monatsbl Augenheilkd. 218:2001;136-139
7. Brownstein S., Fine B.S., Sherman M.E., Zimmerman L.E. Granular dystrophy of the cornea. Light and electron microscopic confirmation of recurrence in a graft. Am J Ophthalmol. 77:1974;701-710
8. Herman S.J., Hughes W.F. Recurrence of hereditary corneal dystrophy following keratoplasty. Am J Ophthalmol. 75:1973;689-694
9. Klintworth G.K., Ferry A.P., Sugar A., Reed J. Recurrence of lattice corneal dystrophy type I in the corneal grafts of two siblings. Am J Ophthalmol. 94:1982;540-546
10. Sundmacher R., Spelsberg H., Reinhard T. Homologous penetrating central limbokeratoplasty in granular and lattice corneal dystrophy. Cornea. 18:1999;664-670
11. Sundmacher R., Reinhard T. Central corneolimbal transplantation under systemic ciclosporin A cover for severe limbal stem cell insufficiency. Graefes Arch Clin Exp Ophthalmol. 234:(suppl):1996;S122-S125
12. Shimazaki J., Kaido M., Shinozaki N., et al. Evidence of long-term survival of donor-derived cells after limbal allograft transplantation. Invest Ophthalmol Vis Sci. 40:1999;1664-1668
13. Henderson T.R., McCall S.H., Taylor G.R., Noble B.A. Do transplanted limbal stem cells survive in vivo long term? Possible techniques to detect donor cell survival by polymerase chain reaction with the amelogenin gene and Y-specific probes. Eye. 11:1997;779-785
14. Henderson T.R., Coster D.J., Williams K.A. The long term outcome of limbal allografts the search for surviving cells. Br J Ophthalmol. 85:2001;604-609
15. Hudde T., Reinhard T., Möller M., et al. Korneosklerale Transplantatentnahme an der Leiche. Erfahrungen der Lions-Hornhautbank Nordrhein-Westfalen in den Jahren 1995 und 1996. Ophthalmologe. 94:1997;780-784. [Corneoscleral transplant excision in the cadaver.Experiences of the North Rhine Westphalia Lions Cornea Bank 1995 and 1996]
16. Hoffmann F. Perforierende Keratoplastik mit Kreuzstichnaht. Erste Ergebnisse. Klin Monatsbl Augenheilkd. 173:1978;696-700. [Cross-stitch suture in perforating keratoplasty]
17. Reinhard T., Hutmacher M., Sundmacher R. Akute und chronische Immunreaktionen nach perforierender Keratoplastik mit normalem Immunrisiko. [Acute and chronic immune reactions after penetrating keratoplasty with normal immune risk] Klin Monatsbl Augenheilkd. 210:1997;139-143
18. Morris R.E., Hoyt E.G., Murphy M.P., et al. Mycophenolic acid and morpholinoethylester (RS-61443) is a new immunosuppressant that prevents and halts heart allograft rejection by selective inhibition of T- and B-cell purine synthesis. Transplant Proc. 22:1990;1659-1662
19. Reis A., Reinhard T., Sundmacher R., et al. Effect of mycophenolate mofetil, cyclosporin A, and both in a murine corneal graft rejection model. Br J Ophthalmol. 82:1998;700-703
20. Ludes B., Clisson I. Short tandem repeat loci analysis in forensic casework. Anthropol Anz. 58:2000;23-27
21. Moretti T.R., Baumstark A.L., Defenbaugh D.A., et al. Validation of short tandem repeats (STRs) for forensic usage performance testing of fluorescent multiplex STR systems and analysis of authentic and simulated forensic samples. J Forensic Sci. 46:2001;647-660
22. Budowle B., Sprecher C.J. Concordance study on population database samples using the PowerPlex 16 Kit and AmpFlSTR Profiler Plus kit and AmpFlSTR COfiler kit. J Forensic Sci. 46:2001;637-641
23. GeneScan [computer program]. Version 3.1. Belle Chasse, LA: GeneScan
24. SPSS [computer program]. Version 10. Chicago: SPSS Inc
25. Sundmacher R., Reinhard T., Althaus C. Homologe zentrale Limbokeratoplastik bei Limbusstammzellschäden. Retrospektive auf 3 Jahre Erfahrung. Ophthalmologe. 94:1997;897-901. [Homologous central limbo-keratoplasty in limbus stem cell damage. Retrospective study of 3 years' experience]
26. Reis A., Megahed H., Reinhard T., et al. Coadministration of the new macrolide immunosuppressant RAD and mycophenolate mofetil in experimental corneal transplantation. Transplantation. 70:2000;1397-1401
27. Reis A., Megahed H., Reinhard T., et al. Synergism of RAD and cyclosporin A in prevention of acute rat corneal allograft rejection. Cornea. 86:2002;81-84
28. Reinhard T., Reis A., Mayweg S., et al. Lokales FK506 bei entzündlichen Erkrankungen von Hornhaut und Bindehaut. Klin Monatsbl Augenheilkd. 219:2002;125-131. [Topical FK506 in inflammatory corneal and conjunctival diseases. A pilot study]
29. Völker-Dieben H.J., Claas F.H., Schreuder G.M., et al. Beneficial effect of HLA-DR matching on the survival of corneal allografts. Transplantation. 70:2000;640-648
30. Reinhard T., Böhringer D., Enczmann J., et al. Improvement of graft prognosis in penetrating normal-risk keratoplasty by HLA class I and II matching. Eye. 18:2004;269-277