Serum galactosyltransferase isoform changes in rheumatoid arthritis

Journal of Rheumatology

Volumn 31, Issue 8, 2004, Pages 1513-1520

  Alavi, Azita ^a,b   Axford, John S ^a   Pool, Andrew J ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b Rheumatology and Clinical Immunology   (United Kingdom)

Author keywords

Galactosyltransferase; Immunoglobulin G; Isoform; Rheumatoid arthritis

Indexed keywords

GALACTOSYLTRANSFERASE; ISOENZYME;

ACIDITY; ADULT; AGED; ARTICLE; CATALYSIS; CLINICAL ARTICLE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BLOOD LEVEL; ENZYME GLYCOSYLATION; ENZYME ISOLATION; FEMALE; HUMAN; ISOELECTRIC FOCUSING; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; RHEUMATOID ARTHRITIS; SIALYLATION; UNITED KINGDOM;

ADULT; AGED; ANIMALS; ARTHRITIS, RHEUMATOID; CASE-CONTROL STUDIES; CATTLE; FEMALE; GALACTOSYLTRANSFERASES; HUMANS; ISOELECTRIC FOCUSING; ISOENZYMES; MALE; MIDDLE AGED; NEURAMINIDASE;

EID: 3442887368     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Axford JS, Mackenzie L, Lydyard PM, Hay FC, Isenberg DA, Roitt IM. Reduced B-cell galactosyltransferase activity in rheumatoid arthritis. Lancet 1987;2:1486-8.
2. Furukawa K, Matsuta K, Takeuchi F, Kosuge E, Miyamoto T, Kobata A. Kinetic study of a galactosyltransferase in the B cells of patients with rheumatoid arthritis. Int Immunol 1990;2:105-12.
3. Axford JS, Sumar N, Alavi A, et al. Changes in normal glycosylation mechanisms in autoimmune rheumatic disease. J Clin Invest 1992;89:1021-31.
4. Wilson IB, Platt FM, Isenberg DA, Rademacher TW. Aberrant control of galactosyltransferase in peripheral B lymphocytes and Epstein-Barr virus transformed B lymphoblasts from patients with rheumatoid arthritis. J Rheumatol 1993;20:1282-7.
5. Alavi A, Axford J. Evaluation of beta 1,4-galactosyltransferase in rheumatoid arthritis and its role in the glycosylation network associated with this disease. Glycoconj J 1995;12:206-10.
6. Keusch J, Lydyard PM, Berger EG. Delves PJ. B lymphocyte galactosyltransferase protein levels in normal individuals and in patients with rheumatoid arthritis. Glycoconj J 1998;15:1093-7.
7. Alavi A, Axford JS, Hay FC, Jones MG. Tissue-specific galactosyltransferase abnormalities in an experimental model of rheumatoid arthritis. Ann Med Interne (Paris) 1998;149:251-60.
8. Rademacher TW, Williams P, Dwek RA. Agalactosyl glycoforms of IgG autoantibodies are pathogenic. Proc Natl Acad Sci USA 1994;91:6123-7.
9. Young A, Sumar N, Bodman K, et al. Agalactosyl IgG: an aid to differential diagnosis in early synovitis. Arthritis Rheum 1991;34:1425-9.
10. Alavi A, Arden N, Spector TD, Axford JS. Immunoglobulin G glycosylation and clinical outcome in rheumatoid arthritis during pregnancy. J Rheumatol 2000;27:1379-85.
11. Kuroda Y, Nakata M, Hirose S, et al. Abnormal IgG galactosylation in MRL-lpr/lpr mice: pathogenic role in the development of arthritis. Pathol Int 2001;51:909-15.
12. Keusch J, Lydyard PM, Delves PJ. The effect on IgG glycosylation of altering beta 1, 4-galactosyltransferase-1 activity in B cells. Glycobiology 1998;8:1215-20.
13. Lo NW, Shaper JH, Pevsner J, Shaper NL. The expanding beta 4-galactosyltransferase gene family: messages from the databanks. Glycobiology 1998;8:517-26.
14. Guo S, Sato T, Shirane K, Furukawa K. Galactosylation of N-linked oligosaccharides by human beta-1,4-galactosyltransferases I, II, III, IV, V, and VI expressed in Sf-9 cells. Glycobiology 2001;11:813-20.
15. Amado M, Almeida R, Schwientek T, Clausen H. Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. Biochim Biophys Acta 1999;1473:35-53.
16. Kido M, Asano M, Iwakura Y, Ichinose M, Miki K, Furukawa K. Normal levels of serum glycoproteins maintained in beta-1, 4-galactosyltransferase I-knockout mice. FEBS Lett 1999;464:75-9.
17. Kotani N, Asano M, Iwakura Y, Takasaki S. Knockout of mouse beta 1,4-galactosyltransferase-1 gene results in a dramatic shift of outer chain moieties of N-glycans from type 2 to type 1 chains in hepatic membrane and plasma glycoproteins. Biochem J 2001;357:827-34.
18. Kotani N, Asano M, Iwakura Y. Takasaki S. Impaired galactosylation of core 2 O-glycans in erythrocytes of beta 1, 4-galactosyltransferase knockout mice. Biochem Biophys Res Commun 1999;260:94-8.
19. Jeddi PA, Bodman-Smith KB, Lund T, et al. Agalactosyl IgG and beta-1,4-galactosyltransferase gene expression in rheumatoid arthritis patients and in the arthritis-prone MRL lpr/lpr mouse. Immunology 1996;87:654-9.
20. Jefferis R, Lund J. Interaction sites on human IgG-Fc for Fc gamma R: current models. Immunol Lett 2002;82:57-65.
21. Malhotra R, Wormald MR, Rudd PM, Fischer PB, Dwek RA, Sim RB. Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein. Nat Med 1995;1:237-43.
22. Soltys AJ, Hay FC, Bond A. et al. The binding of synovial tissue-derived human monoclonal immunoglobulin M rheumatoid factor to immunoglobulin G preparations of differing galactose content. Scand J Immunol 1994;40:135-43.
23. Bond A, Kerr MA, Hay FC. Distinct oligosaccharide content of rheumatoid arthritis-derived immune complexes. Arthritis Rheum 1995;38:744-9.
24. Isenberg DA, Lydyard PM, Axford JS, et al. Galactosylation of IgG associated oligosaccharides. Lancet 1988;2:288.
25. van Zeben D, Rook GA, Hazes JM, et al. Early agalactosylation of IgG is associated with a more progressive disease course in patients with rheumatoid arthritis: results of a follow-up study. Br J Rheumatol 1994;33:36-43.
26. Axford JS, Cunnane G, FitzGerald O, Bland JM, Bresnihan B, Frears ER. Rheumatic disease differentiation using immunoglobulin G sugar printing by high density electrophoresis. J Rheumatol 2003;30:2540-6.
27. Alavi A. The glycosyltransferases. In: Isenberg DA, Rademacher TW, editors. Abnormalities of IgG glycosylation and immunological disorders. New York: John Wiley & Sons; 1996:149-69.
28. Kleene R, Berger EG. The molecular and cell biology of glycosyltransferases. Biochim Biophys Acta 1993;1154:283-325.
29. Shur BD, Evans S, Lu Q. Cell surface galactosyltransferase: current issues. Glycoconj J 1998;15:537-48.
30. Davey RA, Harvie RM, Cahill EJ, Levi JA. Serum galactosyltransferase isoenzymes as markers for solid tumours in humans. Eur J Cancer Clin Oncol 1984;20:75-9.
31. Strous GJ. Golgi and secreted galactosyltransferase. CRC Crit Rev Biochem 1986;21:119-51.
32. Dinter A, Berger EG. The regulation of cell- and tissue-specific expression of glycans by glycosyltransferases. Adv Exp Med Biol 1995;376:53-82.
33. Zhang SW, Xu SL, Cai MM, et al. Effect of p58GTA on beta-1, 4-galactosyltransferase 1 activity and cell-cycle in human hepatocarcinoma cells. Mol Cell Biochem 2001;221:161-8.
34. Delves PJ, Lund T, Axford JS, et al. Polymorphism and expression of the galactosyltransferase-associated protein kinase gene in normal individuals and galactosylation-defective rheumatoid arthritis patients. Arthritis Rheum 1990;33:1655-64.
35. Furukawa K, Roth S. Embryonic and adult forms of two galactosyltransferases differ in their degrees of sialylation. Eur J Biochem 1985;150:175-80.
36. Gerber AC, Kozdrowski I, Wyss SR, Berger EG. The charge heterogeneity of soluble human galactosyltransferases isolated from milk, amniotic fluid and malignant ascites. Eur J Biochem 1979;93:453-60.
37. Davey R, Bowen R, Cahill J. The analysis of soluble galactosyltransferase isoenzyme patterns using high resolution agarose isoelectric focusing. Biochem Int 1983;6:643-51.
38. Davey R, Harvie R, Cahill J, Levi J. Serum galactosyltransferase isoenzyme patterns of cancer patients with liver involvement. Br J Cancer 1986;53:211-5.
39. Uemura M, Sakaguchi T, Uejima T, Nozawa S, Narimatsu H. Mouse monoclonal antibodies which recognize a human (beta 1-4)galactosyl-transferase associated with tumor in body fluids. Cancer Res 1992;52:6153-7.
40. Endo T, Amano J, Berger EG, Kobata A. Structure identification of the complex-type, asparagine-linked sugar chains of beta-D-galactosyl-transferase purified from human milk. Carbohydr Res 1986;150:241-63.
41. Amano J, Straehl P, Berger EG, Kochibe N, Kobata A. Structures of mucin-type sugar chains of the galactosyltransferase purified from human milk. Occurrence of the ABO and Lewis blood group determinants. J Biol Chem 1991;266:11461-77.
42. Malissard M, Berger EG. Improving solubility of catalytic domain of human beta-1,4-galactosyltransferase 1 through rationally designed amino acid replacements. Eur J Biochem 2001;268:4352-8.
43. Soltys A, Alavi A, Dalziel M, Axford J. Galactosyltransferase isoenzymes in rheumatoid arthritis and healthy individuals [abstract]. Glycosylation Dis 1994;1:204.
44. Arnett FC, Edworthy SM, Bloch DA, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
45. Qian GX, Liu CK, Waxman S. Abnormal isoelectric focusing patterns of serum galactosyltransferase activity in patients with liver neoplasia. Proc Soc Exp Biol Med 1984;175:21-4.
46. Kessel D, Allen J. Elevated plasma sialyltransferase in the cancer patient. Cancer Res 1975;35:670-2.
47. Basset C, Durand V, Mimassi N, Pennec YL, Youinou P, Dueymes M. Enhanced sialyltransferase activity in B lymphocytes from patients with primary Sjogren's syndrome. Scand J Immunol 2000;51:307-11.