In vitro inhibition effects of some new sulfonamide inhibitors on human carbonic anhydrase I and II

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 19, Issue 3, 2004, Pages 257-261

  Çakir, Ümit ^a   Uǧraş, Halil Ibrahim ^a   Özensoy, Özen ^a   Sinan, Selma ^a   Arslan, Oktay ^a  

^a BALIKESIR UNIVERSITY   (Turkey)

Author keywords

Carbonic anhydrase isozymes; Inhibition; Sulfonamides

Indexed keywords

2 (3 CYCLOHEXENE 1 CARBAMIDO) 1,3,4 THIADIAZOLE 5 SULFONAMIDE; 2 (4,7,10 TRIOXA TETRADECANOYLAMIDO) 1,3,4 THIADIAZOLE 5 SULFONAMIDE; 2 (8 METHOXYCOUMARIN 3 CARBAMIDO) 1,3,4 THIADIAZOLE 5 SULFONAMIDE; 2 (9 OCTADECENOYLAMIDO) 1,3,4 THIADIAZOLE 5 SULFONAMIDE; 2 (COUMARIN 3 CARBAMIDO) 1,3,4 THIADIAZOLE 5 SULFONAMIDE; 4 (3 CYCLOHEXENE 1 CARBAMIDO)METHYLBENZENESULFONAMIDE; ACETAZOLAMIDE; CARBONATE DEHYDRATASE I INHIBITOR; CARBONATE DEHYDRATASE II INHIBITOR; CARBONATE DEHYDRATASE INHIBITOR; SULFONAMIDE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG RESEARCH; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME PURIFICATION; GLAUCOMA; HUMAN; IN VITRO STUDY; INTRAOCULAR PRESSURE; MYOPIA; PRIORITY JOURNAL; STRUCTURE ANALYSIS; VISUAL IMPAIRMENT;

CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; ISOENZYMES; MOLECULAR STRUCTURE; SULFONAMIDES;

EID: 3442884300     PISSN: 14756366     EISSN: None     Source Type: Journal    
DOI: 10.1080/14756360410001689586     Document Type: Article

References (15)

1. Supuran, C.T., Scozzafava, A. and Casini, A. (2003) Med. Res. Rev. 23, 146-189.
2. Chegwidden, W.R., Spencer, I.M. and Supuran, C.T. (2001) "The roles of carbonic anhydrase isozymes in cancer", In: Xue, G., Xue, Y., Xu, Z., Holmes, R., Hammond, G.L. and Lim, H.A., eds, Gene Families: Studies of DNA, RNA, Enzymes and Proteins (World Scientific, Singapore), pp 157-170.
3. Supuran, C.T. and Scozzafava, A. (2001) Curr. Med. Chem-Imm., Endoc. Metab. Agents 1, 61-97.
4. Hermann, C.K.F., Champbell, J.A., Greenwood, T.D., Lewis, J.A. and Wolfe, J.F. (1992) J. Org. Chem. 57, 5328.
5. Teeninga, H. and Engberts, J.B.F.N. (1983) J. Org. Chem. 48, 537.
6. Supuran, C.T., Ilies, M.A. and Scozzafava, A. (1998) Eur. J. Med. Chem. 33, 739-751.
7. Woltersdorf, O.W., Jr., Schwam, H., Bicking, J.B., Brown, S.L., deSolms, S.J., Fishman, D.R., Graham, S.L., Gautheron, P.D., Hoffman, J.M., Larson, R.D., Lee, W.S., Michelson, S.R., Robb, C.M., Share, N.N., Shepard, K.L., Smith, R.L., Sondey, J.M., Strohmaier, K.M., Sugrue, M.F. and Viader, M.P. (1989) J. Med. Chem. 32, 2486.
8. Arslan, O., Nalbantoglu, B., Demir, N., Özdemir, H. and Küfrevioglu, O.I. (1996) Turk. J. Med. Sci. 26, 163-166.
9. Bradford, M.M. (1976) Anal. Biochem. 72, 248.
10. Warburg, O. and Christian, W. (1941) Biochemistry 310, 384.
11. Maren, T.H. (1960) J. Pharm. Exp. Ther. 130, 26-29.
12. Arslan, O. (2001) Biochemistry (Moscow) 66, 982-983.
13. Sanyal (1982) Comp. Biochem. Physiol. 73, 937-944.
14. Wistrand, P.J. and Lindqvist, A. (1991) In: Botre, F., Gros, G. and Storey, B.T., eds, Carbonic anhydrase: from Biochemistry and Genetics to Physiology and Clinical Medicine (VCH Verlagsgesellschaft, Weinheim), pp 352-374.
15. Arslan, O., Cakir, U. and Ugras, H.I. (2002) Biochemistry (Moscow) 67(9), 1273-1276.