Changes in the ratio of Tc1/Tc2 and Th1/Th2 cells but not in subtypes of NK-cells in preeclampsia

International Journal of Molecular Sciences

Volumn 8, Issue 6, 2007, Pages 492-504

  Hu, Yali ^a   Zhou, Jianjun ^a   Hao, Sha ^b   Wang, Zhiqun ^a   Dai, Yiming ^a   Ling, Jingxian ^a   Hou, Yayi ^b  

^a THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

Decidua; Human; NK cell; Preeclampsia; Type 1 type 2 immunity; uNK cell

Indexed keywords

CD56 ANTIGEN; CD69 ANTIGEN; CD94 ANTIGEN;

ADULT; ANTIGEN PRESENTING CELL; ARTICLE; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; DECIDUA; FEMALE; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNOPHENOTYPING; NATURAL KILLER CELL; PATHOGENESIS; PREECLAMPSIA; TH1 CELL; TH2 CELL;

EID: 34347399950     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/i8060492     Document Type: Article

References (32)

1. Redman, C.W.; Sargent, I.L. Latest advances in understanding preeclampsia. Science 2005, 308, 1592-1594.
2. Toder, V.; Blank, M.; Gleicher, N.; Voljovich, I.; Mashiah, S.; Nebel, L. Activity of natural killer cells in normal pregnancy and edema-proteinuria- hypertension gestosis. Am. J. Obstet. Gynecol. 1983, 145, 7-10.
3. Alanen, A.; Lassila, O. Deficient natural killer cell function in preeclampsia. Obstet. Gynecol. 1982, 60, 631-634.
4. Hill, J.A.; Hsia, S.; Doran, D.M.; Bryans, C.I. Natural killer cell activity and antibody dependent cell-mediated cytotoxicity in preeclampsia. J. Reprod. Immunol. 1986, 9, 205-212.
5. Wilczynski, J.R.; Tchorzewski, H.; Banasik, M.; Glowacka, E.; Wieczorek, A.; Lewkowicz, P.; Malinowski, A.; Szpakowski, M.; Wilczynski, J. Lymphocyte subset distribution and cytokine secretion in third trimester decidua in normal pregnancy and preeclampsia. Eur. J. Obstet. Gynecol. Reprod. Biol. 2003, 109, 8-15.
6. Bujold, E.; Chaiworapongsa, T.; Romero, R.; Gervasi, M.T.; Espinoza, J.; Goncalves, L.F.; Berman, S.; Yoon, B.H.; Kim, Y.M. Neonates born to pre-eclamptic mothers have a higher percentage of natural killer cells (CD3-/CD56+16+) in umbilical cord blood than those without pre-eclampsia. J. Matern. Fetal Neonatal. Med. 2003 14,305-312.
7. King, A.; Balendran, N.; Wooding, P.; Carter, N.P.; Loke, Y.W. CD3- leukocytes present in the human uterus during early placentation: phenotypic and morphologic characterization of the CD56++ population. Dev. Immunol. 1991, 1, 169-190.
8. Christmas, S.E.; Bulmer, J.N.; Meager, A.; Johnson, P.M. Phenotypic and functional analysis of human CD3- decidual leucocyte clones. Immunology 1990, 71, 182-189.
9. Eidukaite, A.; Siaurys, A.; Tamosiunas, V. Differential expression of KIR/NKAT2 and CD94 molecules on decidual and peripheral blood CD56bright and CD56dim natural killer cell subsets. Fertil. Steril. 2004, 81, 863-868.
10. Ntrivalas, E.I.; Kwak-Kim, J.Y.; Gilman-Sachs, A.; Chung-Bang, H.; Ng, S.C.; Beaman, K.D.; Mantouvalos, H.P.; Beer, A.E. Status of peripheral blood natural killer cells in women with recurrent spontaneous abortions and infertility of unknown aetiology. Hum. Reprod. 2001, 16, 855-861.
11. Thum, M.Y.; Bhaskaran, S.; Abdalla, H.I.; Ford, B.; Sumar, N.; Shehata, H.; Bansal, A.S. An increase in the absolute count of CD56dimCD16+CD69+ NK cells in the peripheral blood is associated with a poorer IVF treatment and pregnancy outcome. Hum. Reprod. 2004, 19, 2395-2400.
12. Coulam, C.B.; Roussev, R.G. Correlation of NK cell activation and inhibition markers with NK cytoxicity among women experiencing immunologic implantation failure after in vitro fertilization and embryo transfer. J. Assist. Reprod. Genet. 2003, 20, 58-62.
13. Merviel, P.; Carbillon, L.; Challier , J.C.; Rabreau, M.; Beaufils, M.; Uzan, S. Pathophysiology of preeclampsia: links with implantation disorders. Eur. J. Obstet. Gynecol. Reprod. Biol. 2004, 115, 134-147.
14. Saito, S.; Umekage, H.; Sakamoto, Y.; Sakai, M.; Tanebe, K.; Sasaki, Y.; Morikawa, H. Increased T-helper-1-type immunity and decreased T-helper-2-type immunity in patients with preeclampsia. Am. J. Reprod. Immunol. 1999, 41, 297-306.
15. Omu, A.E.; Makhseed, M.; al-Qattan, F. The comparative value of interleukin-4 in sera of women with preeclampsia and cord sera. Nutrition 1995, 11, 688-691.
16. Jonsson, Y.; Ekerfelt, C.; Berg, G.; Nieminen, K.; Sharma, S.; Ernerudh, J.; Matthiesen, L. Systemic Th1/Th2 cytokine responses to paternal and vaccination antigens in preeclampsia: no differences compared with normal pregnancy. Am. J. Reprod. Immunol. 2004, 51, 302-310.
17. Arriaga-Pizano, L.; Jimenez-Zamudio, L.; Vadillo-Ortega, F.; Martinez-Flores, A.; Herrerias-Canedo, T.; Hernandez-Guerrero, C. The predominant Th1 cytokine profile in maternal plasma of preeclamptic women is not reflected in the choriodecidual and fetal compartments. J. Soc. Gynecol. Investig. 2005, 12, 335-342.
18. Iezzi, G.; Boni, A.; Degl'Innocenti, E.; Grioni, M.; Bertilaccio, M.T.; Bellone, M. Type 2 cytotoxic T lymphocytes modulate the activity of dendritic cells toward type 2 immune responses. J. Immunol. 2006, 177, 2131-2137
19. Stallmach, T.; Hebisch, G.; Orban, P.; Lu, X. Aberrant positioning of trophoblast and lymphocytes in the feto-maternal interface with pre-eclampsia. Virchows Arch. 1999, 434, 207-211.
20. Poole, J.A.; Claman, H.N. Immunology of pregnancy. Implications for the mother. Clin. Rev. Allergy Immunol. 2004, 26, 161-70
21. Yang, L.; Hu, Y.; Hou, Y. Effexts of 17β-estradiol on the maturation,nuclear kappa B p65 and functions of murine spleen CD11c-positive dendritic cells. Mol. Immunol. 2006, 43, 357-366.
22. Yang, L.; Hu, Y.; Li, X.; Zhao, J.; Hou, Y. Prolactin modulates the functions of murine spleen CD11c-positive dendritic cells. Int. Immunopharmacol. 2006, 6, 1478-1486.
23. Schondorf, T.; Engel, H.; Lindemann, C. Cellular characteristics of peripheral blood lymphocytes and tumour-infiltrating lymphocytes in patients with gynaecological tumours. Cancer Immunol. Immunother. 1997, 44, 88-96.
24. Sindram-Trujillo, A.P.; Scherjon, S.A.; van Hulst-van Miert, P.P.; van Schip, J.J.; Kanhai, H.H.; Roelen, D.L.; Claas, F.H. Differential distribution of NK cells in decidua basalis compared with decidua parietalis after uncomplicated human term pregnancy. Hum. Immunol. 2003, 64, 921-929.
25. Bulmer, J.N.; Lash, G.E. Human uterine natural killer cells: a reappraisal. Mol. Immunol. 2005, 2, 511-521.
26. Coulam, C.B.; Roussev, R.G. Correlation of NK cell activation and inhibition markers with NK cytoxicity among women experiencing immunologic implantation failure after in vitro fertilization and embryo transfer. J. Assist. Reprod. Genet. 2003, 20, 58-62.
27. Zingoni, A.; Palmieri, G.; Morrone, S.; Carretero, M.; Lopez-Botel, M.; Piccoli, M.; Frati, L.; Santoni, A. CD69-triggered ERK activation and functions are negatively regulated by CD94 / NKG2-A inhibitory receptor. Eur. J. Immunol. 2000, 30, 644-651.
28. Marzio, R.; Mauel, J.; Betz-Corradin, S. CD69 and regulation of the immune function. Immunopharmacol. Immunotoxicol. 1999, 21, 565-582.
29. Saito, S.; Sakai, M. Th1/Th2 balance in preeclampsia. J. Reprod. Immunol. 2003, 59,161-173.
30. Dong, M.; He, J.; Wang, Z.; Xie, X.; Wang, H. Placental imbalance of Th1- and Th2-type cytokines in preeclampsia. Acta Obstet. Gynecol. Scand. 2005, 84, 788-793.
31. Jonsson, Y.; Ruber, M.; Matthiesen, L.; Berg, G.; Nieminen, K.; Sharma, S.; Ernerudh, J.; Ekerfelt, C. Cytokine mapping of sera from women with preeclampsia and normal pregnancies. J. Reprod. Immunol. 2006, 70, 83-91.
32. Liu, J.M.; Zhu, Y.; Xu, Z.W.; Ouyang, W.M.; Wang, J.P.; Liu, X.S.; Cao, Y.X.; Li, Q.; Fang, L.; Zhuang, R.; Yang, A.G.; Jin, B.Q. Dynamic changes of apoptosis-inducing ligands and Th1/Th2 like subpopulations in Hantaan virus-induced hemorrhagic fever with renal syndrome. Clin. Immunol. 2006, 119, 245-25