False positive results of mitochondrial DNA depletion/deletion due to single nucleotide substitutions causing appearance of additional PvuII restriction sites

Diagnostic Molecular Pathology

Volumn 16, Issue 2, 2007, Pages 116-120

  Wȩglewska Jurkiewicz, Anna ^a   Jakóbkiewicz Banecka, Joanna ^b   Pronicka, Ewa ^c   Wȩgrzyn, Grzegorz ^a  

^a UNIVERSITY OF GDA SK   (Poland)

^b INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^c CHILDREN'S MEMORIAL HEALTH INSTITUTE   (Poland)

Author keywords

Human mtDNA mutations; Mitochondrial disease diagnostics; mtDNA deletion; MtDNA depletion

Indexed keywords

AMINO ACID; DNA; GENE PRODUCT; MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; ENDODEOXYRIBONUCLEASE PVUII; TYPE II SITE SPECIFIC DEOXYRIBONUCLEASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; DIAGNOSTIC PROCEDURE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA SEQUENCE; GENETIC POLYMORPHISM; HUMAN; LABORATORY DIAGNOSIS; MITOCHONDRIAL DNA DEPLETION; PRIORITY JOURNAL; RESTRICTION SITE; SINGLE NUCLEOTIDE POLYMORPHISM; ENZYMOLOGY; GENE DELETION; GENETICS; METABOLISM; MITOCHONDRION; MUTATION;

DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA, MITOCHONDRIAL; FALSE POSITIVE REACTIONS; GENE DELETION; HUMANS; MITOCHONDRIA; MITOCHONDRIAL DISEASES; MUTATION; SEQUENCE ANALYSIS, DNA;

EID: 34347399841     PISSN: 10529551     EISSN: None     Source Type: Journal    
DOI: 10.1097/PDM.0b013e3180336271     Document Type: Article

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