First attempts at prediction of DNA strand-break yields using nanodosimetric data

Radiation Protection Dosimetry

Volumn 122, Issue 1-4, 2006, Pages 451-454

  Garty, G ^a,d   Schulte, R ^b   Shchemelinin, S ^a   Grosswendt, B ^c   Leloup, C ^a,d   Assaf, G ^d   Breskin, A ^a   Chechik, R ^a   Bashkirov, V ^b  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c PHYSIKALISCH TECHNISCHE BUNDESANSTALT   (Germany)

^d Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA DAMAGE; DNA STRAND BREAKAGE; DOSIMETRY; ELECTRON RADIATION; IONIZATION; MOLECULAR MODEL; PLASMID; PREDICTION; SIMULATION; STATISTICAL MODEL; ALGORITHM; BIOLOGICAL MODEL; CHEMICAL MODEL; CHEMISTRY; COMPUTER SIMULATION; FACTUAL DATABASE; METHODOLOGY; NANOTECHNOLOGY; PILOT STUDY; RADIATION DOSE; RADIATION EXPOSURE; RADIATION RESPONSE; RADIOMETRY;

ALGORITHMS; COMPUTER SIMULATION; DATABASES, FACTUAL; DNA; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, RADIATION; MICROCHEMISTRY; MODELS, CHEMICAL; MODELS, GENETIC; NANOTECHNOLOGY; PILOT PROJECTS; RADIATION DOSAGE; RADIOMETRY;

EID: 34347391113     PISSN: 01448420     EISSN: None     Source Type: Journal    
DOI: 10.1093/rpd/ncl515     Document Type: Article

References (9)

1. Ward, J. F. DNA damage produced by ionising radiation in mammalian cells: Identities, mechanisms of formation and reparability. Prog. Nucleic Acid Res. Mol. Biol. 35, 95-125 (1988).
2. Shchemelinin, S., Breskin, A., Chechik, R., Pansky, A. and Colautti, P. A nanodosimeter based on single ion counting. In: Microdosimetry - An Interdisciplinary Approach. Goodhead, D., O'Neill, P. and Menzel, H., Eds. (Cambridge: The Royal Society of Chemistry) pp. 375-378. (1997).
3. Garty, G., Shchemelinin, S., Breskin, A., Chechik, R., Assaf, G., Orion, I., Bashkirov, V., Schulte, R. W. and Grosswendt, B. The performance of a novel ion-counting nanodosimeter. Nucl. Instr. Meth. A 491 212-235 (2002).
4. Garty, G. Development of ion-counting nanodosimetry and evaluation of its relevance to radiation biology, Ph.D. dissertation, Weizmann Institute of Science, Rehovot, Israel (2004).
5. Leloup, C. et al. Evaluation of lesion clustering in proton-irradiated DNA. Int. J. Radiat. Biol. 81, 41-54 (2005).
6. Friedland, W., Jacob, P., Paretzke, H. G. and Stork, T. Monte Carlo simulation of the production of short DNA fragments by low-linear energy transfer radiation using higher-order DNA models. Radiat. Res. 150 170-182 (1998).
7. Friedland, W., Jacob, P., Bernhardt, P., Paretzke, H. G. and Dingfelder, M. Simulation of DNA damage after proton irradiation. Radiat. Res., 159, 401-410 (2003).
8. Garty, G., Shchemelinin, S., Breskin, A., Chechik, R., Orion, I., Guedes, G. P., Schulte, R. W., Bashkirov, V. and Grosswendt, B. Wall-less ion-counting nanodosimetry applied to protons. Radiat. Prot. Dosimetry 99, 325-330 (2002).
9. Grosswendt, B. Recent advances of nanodosimetry. Radiat. Prot. Dosimetry 110, 845-850 (2004).