Comparative disposition of pharmacologic markers for cytochrome P-450 mediated metabolism, glomerular filtration rate, and extracellular and total body fluid volume of Greyhound and Beagle dogs

Journal of Veterinary Pharmacology and Therapeutics

Volumn 30, Issue 4, 2007, Pages 314-319

  Kukanich, B ^a   Coetzee, J F ^a   Gehring, R ^a   Hubin, M ^a  

^a KANSAS STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CYTOCHROME P450; INULIN; PHENAZONE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CONTROLLED STUDY; DOG; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG HALF LIFE; ENZYME METABOLISM; EXTRACELLULAR FLUID; EXTRACELLULAR SPACE; FEMALE; GLOMERULUS FILTRATION RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PLASMA PROTEIN BINDING; PRIORITY JOURNAL; PROTEIN BINDING; TOTAL BODY WATER; VALIDATION STUDY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIPYRINE; AREA UNDER CURVE; BIOLOGICAL MARKERS; BODY WATER; CYTOCHROME P-450 ENZYME SYSTEM; DOGS; EXTRACELLULAR SPACE; FEMALE; GLOMERULAR FILTRATION RATE; INJECTIONS, INTRAVENOUS; INULIN; MALE; PEDIGREE;

CANIS FAMILIARIS;

EID: 34347390221     PISSN: 01407783     EISSN: 13652885     Source Type: Journal    
DOI: 10.1111/j.1365-2885.2007.00875.x     Document Type: Article

References (28)

1. Abramson, F.P. (1988) The effect of induction with phenobarbital on the kinetics and bioavailability of antipyrine in the dog. European Journal of Drug Metabolism and Pharmacokinetics, 13, 123 127.
2. Abramson, F.P. Lutz, M.P. (1986a) The effects of phenytoin dosage on the induction of alpha 1-acid glycoprotein and antipyrine clearance in the dog. European Journal of Drug Metabolism and Pharmacokinetics, 11, 135 143.
3. Abramson, F.P. Lutz, M.P. (1986b) The kinetics of induction by rifampin of alpha 1-acid glycoprotein and antipyrine clearance in the dog. Drug Metabolism and Disposition, 14, 46 51.
4. Balani, S.K., Zhu, T., Yang, T.J., Liu, Z., He, B. Lee, F.W. (2002) Effective dosing regimen of 1-aminobenzotriazole for inhibition of antipyrine clearance in rats, dogs, and monkeys. Drug Metabolism and Disposition, 30, 1059 1062.
5. Boothe, D.M., Cullen, J.M., Calvin, J.A., Jenkins, W.L., Brown, S.A., Green, R.A. Corrier, D.E. (1994) Antipyrine and caffeine dispositions in clinically normal dogs and dogs with progressive liver disease. American Journal of Veterinary Research, 55, 254 261.
6. Brodie, B.B. Axelrod, J. (1950) The fate of antipyrine in man. Journal of Pharmacology and Experimental Therapeutics, 98, 97 104.
7. Brown, S.A. (1994) Evaluation of a single-injection method for estimating glomerular filtration rate in dogs with reduced renal function. American Journal of Veterinary Research, 55, 1470 1473.
8. Court, M.H., Hay-Kraus, B.L., Hill, D.W., Kind, A.J. Greenblatt, D.J. (1999) Propofol hydroxylation by dog liver microsomes: assay development and dog breed differences. Drug Metabolism and Disposition, 27, 1293 1299.
9. Dall'Amico, R., Montini, G., Pisanello, L., Piovesan, G., Bottaro, S., Cracco, A.T., Zacchello, G. Zacchello, F. (1995) Determination of inulin in plasma and urine by reversed-phase high-performance liquid chromatography. Journal of Chromatography B: Biomedical Applications, 672, 155 159.
10. Drost, W.T., Couto, C.G., Fischetti, A.J., Mattoon, J.S. Iazbik, C. (2006) Comparison of glomerular filtration rate between greyhounds and non-Greyhound dogs. Journal of Veterinary Internal Medicine, 20, 544 546.
11. Engel, G., Hofmann, U., Heidemann, H., Cosme, J. Eichelbaum, M. (1996) Antipyrine as a probe for human oxidative drug metabolism: identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3- hydroxymethylantipyrine, and norantipyrine formation. Clinical Pharmacology and Therapeutics, 59, 613 623.
12. Gallo, B.V., Slater, J.D., Toledo, C., DeToledo, J. Ramsay, R.E. (1997) Pharmacokinetics and muscle histopathology of intramuscular valproate. Epilepsy Research, 28, 11 15.
13. Gaudino, M. (1949) Kinetics of distribution of inulin between two body water compartments. Proceedings of the Society for Experimental Biology and Medicine, 70, 672 674.
14. Gugler, R., Lain, P. Azarnoff, D.L. (1975) Effect of portacaval shunt on the disposition of drugs with and without first-pass effect. Journal of Pharmacology and Experimental Therapeutics, 195, 416 423.
15. Gunn, H.M. (1978) The proportions of muscle, bone and fat in two different types of dog. Research in Veterinary Science, 24, 277 282.
16. Hay Kraus, B.L., Greenblatt, D.J., Venkatakrishnan, K. Court, M.H. (2000) Evidence for propofol hydroxylation by cytochrome P4502B11 in canine liver microsomes: breed and gender differences. Xenobiotica, 30, 575 588.
17. Henthorn, T.K., Avram, M.J., Frederiksen, M.C. Atkinson, A.J. Jr. (1982) Heterogeneity of interstitial fluid space demonstrated by simultaneous kinetic analysis of the distribution and elimination of inulin and gallamine. Journal of Pharmacology and Experimental Therapeutics, 222, 389 394.
18. Hojo, T., Ohno, R., Shimoda, M. Kokue, E. (2002) Enzyme and plasma protein induction by multiple oral administrations of phenobarbital at a therapeutic dosage regimen in dogs. Journal of Veterinary Pharmacology and Therapeutics, 25, 121 127.
19. Hunter, R.P., Radlinsky, M., Koch, D.E., Corse, M., Pellerin, M.A. Halstead, J. (2005) Plasma pharmacokinetics and synovial fluid concentrations after oral administration of single and multiple doses of celecoxib in Greyhounds. American Journal of Veterinary Research, 66, 1441 1445.
20. KuKanich, B. Borum, S. (2007) The disposition and behavioral effects of methadone administered to Greyhound dogs. Veterinary Anaesthesia and Analgesia, in press.
21. KuKanich, B., Lascelles, B.D.X., Aman, A.M., Mealey, K.L. Papich, M.G. (2005) The effects of inhibiting cytochrome P450 3A, p-glycoprotein, and gastric acid secretion on the oral bioavailability of methadone in dogs. Journal of Veterinary Pharmacology and Therapeutics, 28, 461 466.
22. Loscher, W. (1981) Plasma levels of valproic acid and its metabolites during continued treatment in dogs. Journal of Veterinary Pharmacology and Therapeutics, 4, 111 119.
23. Paulson, S.K., Engel, L., Reitz, B., Bolten, S., Burton, E.G., Maziasz, T.J., Yan, B. Schoenhard, G.L. (1999) Evidence for polymorphism in the canine metabolism of the cyclooxygenase 2 inhibitor, celecoxib. Drug Metabolism and Disposition, 27, 1133 1142.
24. Riviere, J.E. (1999) Distribution in Comparative Pharmacokinetics: Principles, Techniques and Applications, pp. 47 61. Iowa State University Press, Ames, IA.
25. Sams, R.A. Muir, W.W. (1988) Effects of phenobarbital on thiopental pharmacokinetics in Greyhounds. American Journal of Veterinary Research, 49, 245 249.
26. Sams, R.A., Muir, W.W., Detra, R.L. Robinson, E.P. (1985) Comparative pharmacokinetics and anesthetic effects of methohexital, pentobarbital, thiamylal, and thiopental in Greyhound dogs and non-Greyhound, mixed-breed dogs. American Journal of Veterinary Research, 46, 1677 1683.
27. Sharer, J.E. Wrighton, S.A. (1996) Identification of the human hepatic cytochromes P450 involved in the in vitro oxidation of antipyrine. Drug Metabolism and Disposition, 24, 487 494.
28. Zoran, D.L., Riedesel, D.H. Dyer, D.C. (1993) Pharmacokinetics of propofol in mixed-breed dogs and Greyhounds. American Journal of Veterinary Research, 54, 755 760.