Iron homeostasis during transfusional iron overload in β-thalassemia and sickle cell disease: Changes in iron regulatory protein, hepcidin, and ferritin expression

Pediatric Hematology and Oncology

Volumn 24, Issue 4, 2007, Pages 237-243

  Jenkins, Zandra A ^a,e   Hagar, Ward ^a,b   Bowlus, Christopher L ^a,c   Johansson, Hans E ^a,f   Harmatz, Paul ^a,b   Vichinsky, Elliott P ^a,b   Theil, Elizabeth C ^a,d  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^b CHILDREN S HOSPITAL OAKLAND   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF OTAGO   (New Zealand)

^f Biosearch Technologies Inc   (United States)

Author keywords

thalassemia; Ferritin; Hepcidin; Hypertransfusion iron overload; Iron regulatory proteins; Sickle cell disease

Indexed keywords

FERRITIN; HEPCIDIN; IRON; IRON REGULATORY PROTEIN 1; IRON REGULATORY PROTEIN 2; MESSENGER RNA; REGULATOR PROTEIN; RNA; TRANSFERRIN RECEPTOR;

ARTICLE; BETA THALASSEMIA; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; HOMEOSTASIS; HUMAN; HUMAN TISSUE; IRON OVERLOAD; IRON TRANSPORT; LIVER BIOPSY; LIVER LEVEL; OXIDATIVE STRESS; PROTEIN EXPRESSION; RNA ANALYSIS; SICKLE CELL ANEMIA; UPREGULATION;

ANEMIA, SICKLE CELL; ANTIMICROBIAL CATIONIC PEPTIDES; BETA-THALASSEMIA; BLOOD TRANSFUSION; FERRITINS; GENE EXPRESSION REGULATION; HOMEOSTASIS; HUMANS; IRON; IRON OVERLOAD; IRON REGULATORY PROTEIN 1; IRON REGULATORY PROTEIN 2; IRON-REGULATORY PROTEINS; OXIDATIVE STRESS; RNA, MESSENGER;

EID: 34347389655     PISSN: 08880018     EISSN: 15210669     Source Type: Journal    
DOI: 10.1080/08880010701360700     Document Type: Article

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