Peroxisomal metabolism is regulated by an oxygen-recognition system through organelle crosstalk between the mitochondria and peroxisomes

Yeast

Volumn 24, Issue 6, 2007, Pages 491-498

  Fujimura, Shuki ^a   Nakagawa, Tomoyuki ^a   Ito, Takashi ^a   Matsufuji, Yoshimi ^a   Miyaji, Tatsuro ^a   Tomizuka, Noboru ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE   (Japan)

Author keywords

Alcohol oxidase; Isozyme; Methylotrophic yeast; Mitochondria; Oxygen sensing; Peroxisome; Pichia methanolica

Indexed keywords

ALCOHOL OXIDASE; ISOENZYME; METHANOL; OXYGEN;

ARTICLE; CONTROLLED STUDY; FUNGAL METABOLISM; GENE CONTROL; MITOCHONDRION; NONHUMAN; OXYGEN CONCENTRATION; OXYGEN CONSUMPTION; PEROXISOME; PICHIA; PICHIA METHANOLICA; PRIORITY JOURNAL; RESPIRATORY CHAIN; ZYMOGRAPHY;

ALCOHOL OXIDOREDUCTASES; CULTURE MEDIA; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; ISOENZYMES; METHANOL; MITOCHONDRIA; OXYGEN; PEROXISOMES; PICHIA;

PICHIA METHANOLICA;

EID: 34347383532     PISSN: 0749503X     EISSN: 10970061     Source Type: Journal    
DOI: 10.1002/yea.1487     Document Type: Article

References (35)

1. Barros MH, Bandy B, Tahara EB, Kowaltowski AJ. 2004. Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae. J Biol Chem 279: 49883-49888.
2. Bhatnagar A, Raghavendra PR, Kranthi BV, Rangarajan PN. 2004. Yeast cytochrome c is a sequence-specific DNA-binding protein. Biochem Biophys Res Commun 321: 900-904.
3. Bunn HF, Poyton RO. 1996. Oxygen sensing and molecular adaptation to hypoxia. Physiol Rev 76: 839-885.
4. Burke PV, Raitt DC, Allen LA, Kellogg EA, Poyton RO. 1997. Effects of oxygen concentration on the expression of cytochrome c and cytochrome c oxidase genes in yeast. J Biol Chem 272: 14705-14712.
5. Castello PR, David PS, McClure T, Crook Z, Poyton RO. 2006. Mitochondrial cytochrome oxidase produces nitric oxide under hypoxic conditions: implications for oxygen sensing and hypoxic signalling in eukaryotes. Cell Metab 3: 277-287.
6. Chelstowska A, Butow RA. 1995. RTG genes in yeast that function in communication between mitochondria and the nucleus are also required for expression of genes encoding peroxisornal proteins. J Biol Chem 270: 18141-18146.
7. Chen Q, Vazquez EJ, Moghaddas S, Hoppel CL, Lesnefsky EJ. 2003. Production of reactive oxygen species by mitochondria: central role of complex III. J Biol Chem 278: 36027-36031.
8. Cheng C, Kacherovsky N, Dombek KM, et al. 1994. Identification of potential target genes for Adr1p through characterization of essential nucleotides in UAS1. Mol Cell Biol 14: 3842-3852.
9. Gruzman MB, Titorenko VI, Ashin VV, Lusta KA, Trotsenko YA. 1996. Multiple molecular forms of alcohol oxidase from the methylotrophic yeast Pichia methanolica. Biochemistry (Moscow) 61: 1537-1544.
10. Gurvitz A, Hiltunen JK, Erdmann R, et al. 2001. Saccharomyces cerevisiae Adr1p governs fatty acid beta-oxidation and peroxisome proliferation by regulating POX1 and PEX11. J Biol Chem 276: 31825-31830.
11. Guzy RD, Schumacker PT. 2006. Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia. Exp Physiol 91: 807-819.
12. HenzIer HJ, Schedel M. 1991. Suitability of the shaking flask for oxygen-supply to microbiological cultures. Bioprocess Eng 7: 123-131.
13. Hochachka PW, Buck LT, Doll CJ, Land SC. 1996. Unifying theory of hypoxia tolerance: molecular metabolic defense and rescue mechanisms for surviving oxygen lack. Proc Natl Acad Sci USA 93: 9493-9498.
14. Hon T, Dodd A, Dirmeier R, et al. 2003. A mechanism of oxygen sensing in yeast. Multiple oxygen-responsive steps in the haem biosynthetic pathway affect Hap1 activity. J Biol Chem 278: 50771-50780.
15. Huh WK, Falvo JV, Gerke LC, et al. 2003. Global analysis of protein localization in budding yeast. Nature 425: 686-691.
16. Kwast KE, Burke PV, Poyton RO. 1998. Oxygen sensing and the transcriptional regulation of oxygen-responsive genes in yeast. J Exp Biol 201: 1177-1195.
17. Lin-Cereghino GP, Godfrey L, de la Cruz BJ, et al. 2006. Mxr1p, a key regulator of the methanol utilization pathway and peroxisomal genes in Pichia pastoris. Mol Cell Biol 26: 883-897.
18. Guzy RD, Hoyos B, Robin E, et al. 2005. Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. Cell Metab 1: 401-408.
19. McDaniel LE, Bailey EG. 1969. Effect of shaking speed and type of closure on shake flask cultures. Appl Environ Microbiol 17: 286-290.
20. Nakagawa T, Inagaki A, Ito T, et al. 2006. Regulation of two distinct alcohol oxidase promoters in the methylotrophic yeast Pichia methanolica. Yeast 23: 15-22.
21. Nakagawa T, Ito T, Fujimura S, et al. 2004. Molecular characterization of the glutathione-dependent formaldehyde dehydrogenase gene FLD1 from the methylotrophic yeast Pichia methanolica. Yeast 21: 445-453.
22. Nakagawa T, Mizumura T, Mukaiyama H, et al. 2002. Physiological role of the second alcohol oxidase gene MOD2 in the methylotrophic growth of Pichia methanolica. Yeast 19: 1067-1073.
23. Nakagawa T, Mukaiyama H, Yurimoto H, Sakai Y, Kato N. 1999. Alcohol oxidase hybrid oligomers formed in vivo and in vitro. Yeast 15: 1223-1230.
24. Nakagawa T, Sakai Y, Mukaiyama H, et al. 2001. Analysis of alcohol oxidase isozymes in gene-disrupted strains of methylotrophic yeast Pichia methanolica. J Biosci Bioeng 91: 225-227.
25. Nakagawa T, Uchimura T, Komagata K. 1996. Isozymes of methanol oxidase in a methanol-utilizing yeast, Pichia methanolica IAM 12 901. J Ferment Bioeng 81: 498-503.
26. Poyton RO. 1999. Models for oxygen sensing in yeast: implications for oxygen-regulated gene expression in higher eukaryotes. Respir Physiol 115: 119-133.
27. Poyton RO, Dirmeier R, O'Brien K, David P, Dodd A. 2004. Experimental strategies for analyzing oxygen sensing in yeast. Methods Enzymol 381: 644-662.
28. Raymond CK, Bukowski T, Holderman SD, et al. 1998. Development of the methylotrophic yeast Pichia methanolica for the expression of the 65 kDa isoform of human glutamate decarboxylase. Yeast 14: 11-23.
29. Sakai Y, Yurimoto H, Matsuo H, Kato N. 1998. Regulation of peroxisomal proteins and organelle proliferation by multiple carbon sources in the methylotrophic yeast, Candida boidinii. Yeast 14: 1175-1187.
30. Schuller HJ. 2003. Transcriptional control of nonfermentative metabolism in the yeast Saccharomyces cerevisiae. Curr Genet 43: 139-160.
31. Simon MM, Pavlik P, Hartig A, et al. 1995. A C-terminal region of the Saccharomyces cerevisiae transcription factor ADR1 plays an important role in the regulation of peroxisome proliferation by fatty acids. Mol Gen Genet 249: 289-296.
32. Skoneczny M, Rytka J. 2000. Oxygen and haem regulate the synthesis of peroxisomal proteins: catalase A, acyl-CoA oxidase and Pex1p in the yeast Saccharomyces cerevisiae; the regulation of these proteins by oxygen is not mediated by haem. Biochem J 350: 313-319.
33. Toh-e A, Ueda Y, Kakimoto S, Oshima Y. 1973. Isolation and characterization of acid phosphatase mutants in Saccharomyces cerevisiae. J Bacteriol 113: 727-738.
34. Young ET, Dombek KM, Tachibana C, Ideker T. 2003. Multiple pathways are co-regulated by the protein kinase Snf1 and the transcription factors Adr1 and Cat8. J. Biol Chem 278: 26146-26158.
35. Zitomer RS, Lowry CV. 1992. Regulation of gene expression by oxygen in Saccharomyces cerevisiae. Microbiol Rev 56: 1-11.