A great deal of learning from the natural course of chronic hepatitis B virus infection

Journal of Gastroenterology and Hepatology (Australia)

Volumn 22, Issue 7, 2007, Pages 962-964

  Chien, Rong Nan ^a  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; HEPATITIS B(E) ANTIGEN; LAMIVUDINE; VIRUS DNA;

ANTIVIRAL THERAPY; DISEASE COURSE; EDITORIAL; HEPATITIS B; HISTOLOGY; HUMAN; INCIDENCE; LIVER CIRRHOSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEROCONVERSION; TREATMENT OUTCOME;

EID: 34347382824     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2007.05063.x     Document Type: Editorial

References (14)

1. Chu CM, Karayiannis P, Fowler MJF et al. Natural history of chronic hepatitis B virus infection in Taiwan: studies of hepatitis B virus DNA in serum. Hepatology 1985 5 : 431 4.
2. Chen CJ, Yang HI, Su J et al. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA 2006 295 : 65 73.
3. Iloeje UH, Yang HI, Su J et al. Predicting cirrhosis risk based on the level of circulating hepatitis B viral load. Gastroenterology 2006 130 : 678 86.
4. Kao JH, Chen DS. HBV genotype: epidemiology and implications regarding natural history. Curr. Hepat. Rep. 2006 5 : 5 13.
5. Kao JH, Chen PJ, Lai MY, Chen DS. Basal core promoter mutations of hepatitis B virus increase the risk of hepatocellular carcinoma in hepatitis B carriers. Gastroenterology 2003 124 : 327 34.
6. Chu CM, Hung SJ, Lin J, Tai DI, Liaw YF. Natural history of hepatitis B e antigen to antibody seroconversion in patients with normal serum aminotransferase levels. Am. J. Med. 2004 116 : 829 34.
7. Yuen M-F. Revisiting the natural history of chronic hepatitis B: Impact of new concepts on clinical management. J. Gastroenterol. Hepatol. 2007 22 : 973 6.
8. Chu CM, Liaw YF. Chronic hepatitis B virus infection acquired in childhood: special emphasis on prognostic and therapeutic implication of delayed HBeAg seroconversion. J. Viral Hepat. 2007 14 : 147 52.
9. Chu CM, Liaw YF. Spontaneous relapse of hepatitis in inactive HBsAg carrier from Taiwan. Hepatology Int. 2007 (in press).
10. Liaw YF. Hepatitis B virus replication and liver disease progression: the impact of antiviral therapy. Antivir. Ther. 2006 11 : 669 79.
11. Hsu YS, Chien RN, Yeh CT et al. Long-term outcome following spontaneous HBeAg seroconversion in patients with chronic hepatitis B. Hepatology 2002 35 : 1522 7.
12. Nicoll A, Locarnini S. Present and future directions in the treatment of chronic hepatitis B infection. J. Gastroenterol. Hepatol. 1997 12 : 843 54.
13. Park BK, Park YN, Ahn SH et al. Long-term outcome of chronic hepatitis B based on histological grade and stage. J. Gastroenterol. Hepatol. 2007 22 : 383 8.
14. Chien RN, Liaw YF, Atkin M. Pretherapy alanine transaminase level as a determinant for hepatitis B e antigen seroconversion during lamivudine therapy in patients with chronic hepatitis B. Hepatology 1999 30 : 770 4.