Advanced chronic obstructive pulmonary disease: Innovative approaches to palliation

Journal of Palliative Medicine

Volumn 10, Issue 3, 2007, Pages 783-797

  Rocker, Graeme M ^a,c   Sinuff, Tasnim ^b   Horton, Robert ^a   Hernandez, Paul ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c QUEEN ELIZABETH II HEALTH SCIENCES CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AIRWAY OBSTRUCTION; CAUSE OF DEATH; CHRONIC OBSTRUCTIVE LUNG DISEASE; HUMAN; MEDICAL SPECIALIST; PALLIATIVE THERAPY; PULMONOLOGY; QUALITY OF LIFE; REVIEW; TERMINAL CARE;

DIFFUSION OF INNOVATION; HUMANS; PALLIATIVE CARE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; TERMINAL CARE; UNITED STATES;

EID: 34347374748     PISSN: 10966218     EISSN: None     Source Type: Journal    
DOI: 10.1089/jpm.2007.9951     Document Type: Review

References (129)

1. Gore JM, Brophy CJ, Greenstone MA: How well do we care for patients with end stage chronic obstructive pulmonary disease (COPD)? A comparison of palliative care and quality of life in COPD and lung cancer. Thorax 2000;55:1000-1006.
2. Solano JP, Gomes B, Higginson IJ: A comparison of symptom prevalence in far advanced cancer, AIDS, heart disease, chronic obstructive pulmonary disease and renal disease. J Pain Symptom Manage 2006;31:58-69.
3. Edmonds P, Karlsen S, Khan S, Addington-Hall J: A comparison of the palliative care needs of patients dying from chronic respiratory diseases and lung cancer. Palliat Med 2001;15:287-295.
4. Lacasse Y, Brooks D, Goldstein RS: Trends in the epidemiology of COPD in Canada, 1980 to 1995. COPD and Rehabilitation Committee of the Canadian Thoracic Society. Chest 1999;116:306-313.
5. Respiratory Disease in Canada. Canadian Institute for Health Information, Canadian Lung Association, Health Canada, Statistics Canada. 2001.
6. Murray CJ, Lopez AD. Mortality by cause for eight regions of the world: Global Burden of Disease Study. Lancet 1997;349:1269-1276.
7. Au DH, Udris EM, Fihn SD, McDonell MB, Curtis JR: Differences in health care utilization at the end of life among patients with chronic obstructive pulmonary disease and patients with lung cancer. Arch Intern Med 2006;166:326-331.
8. Bailey PH: The dyspnea-anxiety-dyspnea cycle - COPD patients' stories of breathlessness: "It's scary /when you can't breathe." Qual Health Res 2004;14:760-78.
9. Jones I, Kirby A, Ormiston P, Loomba Y, Chan KK, Rout J, Nagle J, Wardman L, Hamilton S: The needs of patients dying of chronic obstructive pulmonary disease in the community. Fam Pract 2004;21:310-313.
10. Elkington H, White P, Addington-Hall J, Higgs R, Edmonds P: The healthcare needs of chronic obstructive pulmonary disease patients in the last year of life. Palliat Med 2005;19:485-491.
11. Elkington H, White P, Addington-Hall J, Higgs R, Pettinari C: The last year of life of COPD: A qualitative study of symptoms and services. Respir Med 2004; 98:439-445.
12. Shah S, Blanchard M, Tookman A, Jones L, Blizard R, King M: Estimating needs in life threatening illness: A feasibility study to assess the views of patients and doctors. Palliat Med 2006;20:205-210.
13. Luddington L, Cox S, Higginson I, Livesley B: The need for palliative care for patients with non-cancer diseases: A review of the evidence. Int J Palliat Nurs 2001;7: 221-226.
14. O'Donnell DE, Aaron S, Bourbeau J, Hernandez P, Marciniuk D, Balter M, Ford G, Gervais A, Goldstein R, Hodder R, Maltais F, Road J; Canadian Thoracic Society: Canadian Thoracic Society recommendations for management of chronic obstructive pulmonary disease - 2003. Can Respir J 2003;10(Suppl A):11A-65A.
15. Abrahm JL, Hansen-Flaschen J: Hospice care for patients with advanced lung disease. Chest 2002;121:220-229.
16. Claessens MT, Lynn J, Zhong Z, Desbiens NA, Phillips RS, Wu AW, Harrell FE Jr, Connors AF Jr: Dying with lung cancer or chronic obstructive pulmonary disease: Insights from SUPPORT. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments. J Am Geriatr Soc 2000;48(5 Suppl):S146-153.
17. Elkington H, White P, Higgs R, Pettinari CJ: GPs' views of discussions of prognosis in severe COPD. Fam Pract 2001;18:440.
18. Guthrie SJ, Hill KM, Muers ME: Living with severe COPD. A qualitative exploration of the experience of patients in Leeds. Respir Med 2001;95:196-204.
19. Selecky PA, Eliasson CA, Hall RI, Schneider RF, Varkey B, McCaffree DR: Palliative and end-of-life care for patients with cardiopulmonary diseases: American College of Chest Physicians position statement. Chest 2005;12: 3599-3610.
20. Lynn J, Ely EW, Zhong Z, McNiff KL, Dawson NV, Connors A, Desbiens NA, Claessens M, McCarthy EP: Living and dying with chronic obstructive pulmonary disease. J Am Geriatr Soc 2000;48(5 Suppl):S91-S100.
21. Tranmer JE, Heyland D, Dudgeon D, Groll D, Squires-Graham M, Coulson K: Measuring the symptom experience of seriously ill cancer and noncancer hospitalized patients near the end of life with the memorial symptom assessment scale. J Pain Symptom Manage 2003;25:420-429.
22. Lunney JR, Lynn J, Foley DJ, Lipson S, Guralnik JM: Patterns of functional decline at the end of life. JAMA 2003;289:2387-2392.
23. Heffner JE, Barbieri C: End-of-life care preferences of patients enrolled in cardiovascular rehabilitation programs. Chest 2000;117:1474-1481.
24. Rocker G, Heyland D, Groll D, Dodek P, Kutsogianis D, Lazar N: Meeting the needs of patients with end stage COPD: A multicentre study. Am J Respir Crit Care Med 2004;169:A50.
25. Fried TR, Bradley EH: What matters to seriously ill older persons making end-of-life treatment decisions?: A qualitative study. J Palliat Med 2003;6:237-244.
26. Oliver SM: Living with failing lungs: The doctor-patient relationship. Fam Pract 2001;18:430-439.
27. Santo Tomas LH, Varkey B: Improving health-related quality of life in chronic obstructive pulmonary disease. Curr Opin Pulmon Med 2004;10:120-127.
28. Mulcahy P, Buetow S, Osman L, Coster G, Bray Y, White P, Elkinton H: GPs' attitudes to discussing prognosis in severe COPD: An Auckland (NZ) to London (UK) comparison. Fam Pract 2005;22:538-540.
29. Knauft E, Nielsen EL, Engelberg RA, Patrick DL, Curtis JR: Barriers and facilitators to end-of-life care communication for patients with COPD. Chest 2005;127:2188-2196.
30. Grbich C, Maddocks I, Parker D, Brown M, Willis E, Piller N, Hofmeyer A: Identification of patients with non-cancer diseases for palliative care services. Palliat Support Care 2005;3:5-14.
31. Coventry PA, Grande GE, Richards DA, Todd CJ: Prediction of appropriate timing of palliative care for older adults with non-malignant life-threatening disease: A systematic review. Age Ageing 2005;34:218-227.
32. Kite S, Jones K, Tookman A: Specialist palliative care and patients with noncancer diagnoses: The experience of a service. Palliat Med 1999; 13:477-484.
33. Murray SA, Boyd K, Kendall M, Worth A, Benton TF, Clausen H: Dying of lung cancer or cardiac failure: Prospective qualitative interview study of patients and their carers in the community. BMJ 2002;325:929.
34. Hansen-Flaschen J: Chronic obstructive pulmonary disease: The last year of life. Respir Care 2004;49:90-97.
35. Almagro P, Calbo E, Ochoa de Echaguen A, Barreiro B, Quintana S, Heredia JL, Gaurau J: Mortality after hospitalization for COPD. Chest 2002;121:1441-1448.
36. Domingo-Salvany A, Lamarca R, Ferrer M, Garcia-Aymerich J, Alonso J, Felez M, Khalaf A, Marrades RM, Monso E, Serra-Batlles J, Anto JM: Health-related quality of life and mortality in male patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2002;166:680-685.
37. Fan VS, Curtis JR, Tu SP, McDonell MB, Fihn SD: Using quality of life to predict hospitalization and mortality in patients with obstructive lung diseases. Chest 2002; 122:429-436.
38. Nishimura K, Izumi T, Tsukino M, Oga T: Dyspnea is a better predictor of 5-year survival than airway obstruction in patients with COPD. Chest 2002;121:1434-1440.
39. Connors AF Jr, Dawson NV, Thomas C, Harrell FE Jr, Desbiens N, Fulkerson WJ, Kussin P, Bellamy P, Goldman L, Knaus WA: Outcomes following acute exacerbation of severe chronic obstructive lung disease. The SUPPORT investigators (Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments). Am J Respir Crit Care Med 1996;154(4 Pt 1):959-967.
40. Heyland DK, Dodek P, Rocker G, Groll D, Gafni A, Pichora D, Shortt S, Tranmer J, Lazar N, Kutsogiannis J, Lam M; Canadian Researchers End-of-Life Network (CARENET): What matters most in end-of-life care: Perceptions of seriously ill patients and their family members. CMAJ 2006;174:627-633.
41. Celli BR, Cote CG, Marin JM, Casanova C, Montes de Oca M, Mendez RA, Pinto Plata V, Cabral HJ: The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N Engl J Med.2004;350:1005-1012.
42. Soler-Cataluna JJ, Martinez-Garcia MA, Roman Sanchez P, Salcedo E, Navarro M, Ochando R: Severe acute exacerbations and mortality in patients with chronic obstructive pulmonary disease. Thorax 2005;60:925-931.
43. Roy DJ: Palliative care without borders. J Palliat Care 2005;21:131-132.
44. Rocker G: Palliative care for the next decade: Moving beyond cancer. J Palliat Care 2005;21:140-141.
45. Curtis JR, Engelberg RA, Nielsen EL, Au DH, Patrick DL. Patient-physician communication about end-of-life care for patients with severe COPD. Eur Respir J 2004;24:200-205.
46. Heyland DK, Groll D, Rocker G, Dodek P, Gafni A, Tranmer J, Pichora D, Lazar N, Kutsogiannis J, Shortt S, Lam M; Canadian Researchers at the End of Life Network (CARENET): End-of-life care in acute care hospitals in Canada: a quality finish? J Palliat Care 2005;21: 142-150.
47. Nisar M, Earis JE, Pearson MG, Calverley PM: Acute bronchodilator trials in chronic obstructive pulmonary disease. Am Rev Respir Dis 1992;146:555-559.
48. National Emphysema Treatment Trial Research Group: Patients at high risk of death after lung-volume-reduction surgery. N Engl J Med 2001;345:1075-1083.
49. Ferreira G, Feuerman M, Spiegler P: Results of an 8-week, outpatient pulmonary rehabilitation program on patients with and without chronic obstructive pulmonary disease. J Cardiopulm Rehabil 2006;26:54-60.
50. Jennings AL, Davies AN, Higgins JP, Gibbs JS, Broadley KE: A systematic review of the use of opioids in the management of dyspnoea. Thorax 2002;57:939-944.
51. Booth S, Farquhar M, Gysels M, Bausewein C, Higginson IJ: The impact of a breathlessness intervention service (BIS) on the lives of patients with intractable dyspnea: A qulaitative phase 1 study. Palliat Support Care 2006;4:287-293.
52. Medical Research Council: A framework for development and evaluation of RCTs for complex interventions to improve health. London: MRC, 2000.
53. Bausewein C, Farquhar M, Booth S, Gysels M, Higginson IJ: Measurement of breathlessness in advanced disease: A systematic review. Respir Med 2007;101:399-410.
54. Schunemann HJ, Griffith L, Jaeschke R, Goldstein R, Stubbing D, Austin P, Guyatt GH: A comparison of the original chronic respiratory questionnaire with a standardized version. Chest 2003;124:1421-1429.
55. Rutten-van Molken M, Roos B, Van Noord JA: An empirical comparison of the St George's Respiratory Questionnaire (SGRQ) and the Chronic Respiratory Disease Questionnaire (CRQ) in a clinical trial setting. Thorax 1999;54:995-1003.
56. Dyspnea. Mechanisms, assessment, and management: A consensus statement. American Thoracic Society. Am J Respir Crit Care Med 1999;159:321-340.
57. Schunemann HJ, Goldstein R, Mador MJ, McKim D, Stahl E, Puhan M, Griffith LE, Grant B, Austin P, Collins R, Guyatt GH: A randomised trial to evaluate the self-administered standardised chronic respiratory questionnaire. Eur Respir J 2005;25:31-40.
58. Schunemann HJ, Griffith L, Jaeschke R, Goldstein R, Stubbing D, Guyatt GH: Evaluation of the minimal important difference for the feeling thermometer and the St. George's Respiratory Questionnaire in patients with chronic airflow obstruction. J Clin Epidemiol 2003;56: 1170-1176.
59. Schunemann HJ, Griffith L, Stubbing D, Goldstein R, Guyatt GH: A clinical trial to evaluate the measurement properties of 2 direct preference instruments administered with and without hypothetical marker states. Med Decis Making 2003;23:140-149.
60. Schwartzstein RM, Lahive K, Pope A, Weinberger SE, Weiss JW: Cold facial stimulation reduces breathlessness induced in normal subjects. Am Rev Respir Dis 1987; 136:58-61.
61. O'Donnell DE, Aaron S, Bourbeau J, Hernandez P, Marciniuk D, Balter M, Ford G, Gervais A, Goldstein R, Hodder R, Maltais F, Road J: State of the Art Compendium: Canadian Thoracic Society recommendations for the management of chronic obstructive pulmonary disease. Can Respir J;2004;11(Suppl B):7B-59B.
62. Abernethy AP, Currow DC, Frith P, Fazekas BS, McHugh A, Bui C: Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoea. BMJ 2003;327:523-528.
63. Foral PA, Malesker MA, Huerta G, Hilleman DE: Nebulized opioids use in COPD. Chest 2004;125:691-694.
64. Walsh TD, Rivera NI, Kaiko R: Oral morphine and respiratory function amongst hospice inpatients with advanced cancer. Support Care Cancer 2003;11:780-784.
65. Abramson MJ, Crockett AJ, Frith PA, McDonald CF: COPDX: An update of guidelines for the management of chronic obstructive pulmonary disease with a review of recent evidence. Med J Aust 2006;184:342-345.
66. Heffner JE, Fahy B, Hilling L, Barbieri C: Attitudes regarding advance directives among patients in pulmonary rehabilitation. Am J Respir Crit Care Med 1996;154(6 Pt 1):1735-1740.
67. McNeely PD, Hebert PC, Dales RE, O'Connor AM, Wells G, McKim D, Sullivan KE: Deciding about mechanical ventilation in end-stage chronic obstructive pulmonary disease: How respirologists perceive their role. CMAJ 1997;156:177-183.
68. Sullivan KE, Hebert PC, Logan J, O'Connor AM, McNeely PD: What do physicians tell patients with end-stage COPD about intubation and mechanical ventilation? Chest 1996;109:258-264.
69. Curtis JR, Wenrich MD, Carline JD, Shannon SE, Ambrozy DM, Ramsey PG: Patients' perspectives on physician skill in end-of-life care: Differences between patients with COPD, cancer, and AIDS. Chest 2002;122:356-362.
70. Gaber KA, Barnett M, Planchant Y, McGavin CR: Attitudes of 100 patients with chronic obstructive pulmonary disease to artificial ventilation and cardiopulmonary resuscitation. Palliat Med 2004;18:626-629.
71. Johnston SC, Pfeifer MP, McNutt R: The discussion about advance directives. Patient and physician opinions regarding when and how it should be conducted. End of Life Study Group. Arch Intern Med 1995;155: 1025-1030.
72. Wilson KG, Aaron SD, Vandemheen KL, Hebert PC, McKim DA, Fiset V, Graham ID, Sevigny E, O'Connor AM: Evaluation of a decision aid for making choices about intubation and mechanical ventilation in chronic obstructive pulmonary disease. Patient Educ Couns 2005; 57:88-95.
73. Dales RE, O'Connor A, Hebert P, Sullivan K, McKim D, Llewellyn-Thomas H: Intubation and mechanical ventilation for COPD: Development of an instrument to elicit patient preferences. Chest 1999;116:792-800.
74. Mikkelsen RL, Middelboe T, Pisinger C, Stage KB: Anxiety and depression in patients with chronic obstructive pulmonary disease (COPD). A review. Nord J Psychiatry 2004;58:65-70.
75. van Ede L, Yzermans CJ, Brouwer HJ: Prevalence of depression in patients with chronic obstructive pulmonary disease: A systematic review. Thorax 1999;54:688-692.
76. Kim HF, Kunik ME, Molinari VA, Hillman SL, Lalani S, Orengo CA, Petersen NJ, Nahas Z, Goodnight-White S: Functional impairment in COPD patients: the impact of anxiety and depression. Psychosomatics 2000;41:465-471.
77. Ferrer M, Alonso J, Morera J, Marrades RM, Khalaf A, Aguar MC, Plaza V, Prieto L, Anto JM: Chronic obstructive pulmonary disease stage and health-related quality of life. The Quality of Life of Chronic Obstructive Pulmonary Disease Study Group. Ann Intern Med 1997; 127:1072-1079.
78. Lacasse Y, Rousseau L, Maltais F: Prevalence of depressive symptoms and depression in patients with severe oxygen-dependent chronic obstructive pulmonary disease. J Cardiopulm Rehabil 2001;21:80-86.
79. McSweeny AJ, Grant I, Heaton RK, Adams KM, Timms RM: Life quality of patients with chronic obstructive pulmonary disease. Arch Intern Med 1982;142:473-478.
80. Di Marco F, Verga M, Reggente M, Maria Casanova F, Santus P, Blasi F, Allegra L, Centanni S: Anxiety and depression in COPD patients: The roles of gender and disease severity. Respir Med 2006;100:1767-1774.
81. Gudmundsson G, Gislason T, Janson C, Lindberg E, Suppli Ulrik C, Brondum E, Nieminen MM, Aine T, Hallin R, Bakke P: Depression, anxiety and health status after hospitalisation for COPD: A multicentre study in the Nordic countries. Respir Med 2006;100:87-93.
82. Light RW, Merrill EJ, Despars JA, Gordon GH, Mutalipassi LR: Prevalence of depression and anxiety in patients with COPD. Relationship to functional capacity. Chest 1985;87:35-38.
83. Borson S, McDonald GJ, Gayle T, Deffebach M, Lakshminarayan S, VanTuinen C: Improvement in mood, physical symptoms, and function with nortriptyline for depression in patients with chronic obstructive pulmonary disease. Psychosomatics 1992;33:190-201.
84. Runo JR, Ely EW: Treating dyspnea in a patient with advanced chronic obstructive pulmonary disease. West J Med 2001;175:197-201.
85. Manning HL: Dyspnea treatment. Respir Care 2000;45: 1342-1350; discussion 1350-1354.
86. Stage KB, Middelboe T, Pisinger C: Depression and chronic obstructive pulmonary disease (COPD). Impact on survival. Acta Psychiatr Scand 2005;111:320-323.
87. Stapleton RD, Nielsen EL, Engelberg RA, Patrick DL, Curtis JR: Association of depression and life-sustaining treatment preferences in patients with COPD. Chest 2005; 127:328-334.
88. Elofsson LC, Ohlen J: Meanings of being old and living with chronic obstructive pulmonary disease. Palliat Med 2004;18:611-618.
89. Garuti G, Cilione C, Dell'Orso D, Gorini P, Lorenzi MC, Totaro L, Cirelli G, Clini E: Impact of comprehensive pulmonary rehabilitation on anxiety and depression in hospitalized COPD patients. Monaldi Arch Chest Dis 2003; 59:56-61.
90. Booth S, Silvester S, Todd C: Breathlessness in cancer and chronic obstructive pulmonary disease: Using a qualitative approach to describe the experience of patients and carers. Palliat Support Care 2003;1:337-344.
91. Nici L, Donner C, Wouters E, Zuwallack R, Ambrosino N, Bourbeau J, Carone M, Celli B, Engelen M, Fahy B, Garvey C, Goldstein R, Gosselink R, Lareau S, MacIntyre N, Maltais F, Morgan M, O'Donnell D, Prefault C, Reardon J, Rochester C, Schols A, Singh S, Troosters T; ATS/ERS Pulmonary Rehabilitation Writing Committee: American Thoracic Society/European Respiratory Society statement on pulmonary rehabilitation. Am J Respir Crit Care Med 2006;173:1390-1413.
92. Bourbeau J, Mien M, Maltais F, Rouleau M, Beaupre A, Begin R, Renzi P, Nault D, Borycki E, Schwartzman K, Singh R, Collet JP; Chronic Obstructive Pulmonary Disease axis of the Respiratory Network Fonds de la Recherche en Sante du Quebec: Reduction of hospital utilization in patients with chronic obstructive pulmonary disease: A disease-specific self-management intervention. Arch Intern Med 2003;163:585-591.
93. Lacasse Y, Brosseau L, Milne S, Martin S, Wong E, Guyatt GH, Goldstein RS: Pulmonary rehabilitation for chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2002(3):CD003793.
94. O'Donnell DE, D'Arsigny C, Webb KA: Effects of hyperoxia on ventilatory limitation during exercise in advanced chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001;163:892-898.
95. Emtner M, Porszasz J, Burns M, Somfay A, Casaburi R: Benefits of supplemental oxygen in exercise training in nonhypoxemic chronic obstructive pulmonary disease patients. Am J Respir Crit Care Med 2003;168:1034-1042.
96. Garrod R, Paul EA, Wedzicha JA: Supplemental oxygen during pulmonary rehabilitation in patients with COPD with exercise hypoxaemia. Thorax 2000;55:539-543.
97. McDonald CF, Blyth CM, Lazarus MD, Marschner I, Barter CE: Exertional oxygen of limited benefit in patients with chronic obstructive pulmonary disease and mild hypoxemia. Am J Respir Crit Care Med 1995,152(5 Pt 1):1616-1619.
98. Hernandez P, Maltais F, Gursahaney A, Leblanc P, Gottfried SB: Proportional assist ventilation may improve exercise performance in severe chronic obstructive pulmonary disease. J Cardiopulm Rehabil 2001;21:135-142.
99. O'Donnell DE, Sanii R, Giesbrecht G, Younes M: Effect of continuous positive airway pressure on respiratory sensation in patients with chronic obstructive pulmonary disease during submaximal exercise. Am Rev Respir Dis 1988;138:1185-1191.
100. Keilty SE, Ponte J, Fleming TA, Moxham J: Effect of inspiratory pressure support on exercise tolerance and breathlessness in patients with severe stable chronic obstructive pulmonary disease. Thorax 1994;49:990-994.
101. Bianchi L, Foglio K, Porta R, Baiardi R, Vitacca M, Ambrosino N: Lack of additional effect of adjunct of assisted ventilation to pulmonary rehabilitation in mild COPD patients. Respir Med 2002;96:359-367.
102. Hawkins P, Johnson LC, Nikoletou D, Hamnegard CH, Sherwood R, Polkey MI, Moxham J: Proportional assist ventilation as an aid to exercise training in severe chronic obstructive pulmonary disease. Thorax 2002; 57:853-859.
103. Bourbeau J, Nault D, Dang-Tan T: Self-management and behaviour modification in COPD. Patient Educ Couns 2004;52:271-277.
104. Heffner JE, Fahy B, Barbieri C: Advance directive education during pulmonary rehabilitation. Chest. 1996;109(2): 373-379.
105. Haggerty MC, Stockdale-Woolley R, Nair S: Respi-Care. An innovative home care program for the patient with chronic obstructive pulmonary disease. Chest 1991;100: 607-612.
106. Watson PB, Town GI, Holbrook N, Dwan C, Toop LJ, Drennan CJ: Evaluation of a self-management plan for chronic obstructive pulmonary disease. Eur Respir J 1997;10:1267-1271.
107. Emanuel EJ, Fairclough DL, Slutsman J, Emanuel LL: Understanding economic and other burdens of terminal illness: The experience of patients and their caregivers. Ann Intern Med 2000;132:451-459.
108. Grunfeld E, Coyle D, Whelan T, Clinch J, Reyno L, Earle CC, Willan A, Viola R, Coristine M, Janz T, Glossop R: Family caregiver burden: Results of a longitudinal study of breast cancer patients and their principal caregivers. CMAL 2004;8;170:1795.
109. Nijboer C, Tempelaar R, Sanderman R, Triemstra M, Spruijt RJ, van den Bos GA: Cancer and caregiving: The impact on the caregiver's health. Psychooncology 1998; 7:3-13.
110. Nijboer C, Triemstra M, Tempelaar R, Mulder M, Sanderman R, van den Bos GA: Patterns of caregiver experiences among partners of cancer patients. Gerontologist 2000;40:738-746.
111. Higginson IJ, Finlay IG, Goodwin DM, Hood K, Edwards AG, Cook A, Douglas HR, Normand CE: Is there evidence that palliative care teams alter end-of-life experiences of patients and their caregivers? J Pain Symptom Manage 2003;25:150-168.
112. Harding R, Higginson IJ: What is the best way to help caregivers in cancer and palliative care? A systematic literature review of interventions and their effectiveness. Palliat Med 2003;17:63-74.
113. Bailey PH: Death stories: Acute exacerbations of chronic obstructive pulmonary disease. Qual Health Res 2001; 11:322-338.
114. Seamark DA, Blake SD, Seamark CJ, Halpin DM: Living with severe chronic obstructive pulmonary disease (COPD): Perceptions of patients and their carers. An interpretative phenomenological analysis. Palliat Med 2004; 18:619-625.
115. Hughes SL, Weaver FM, Giobbie-Hurder A, Manheim L, Henderson W, Kubal JD, Ulasevich A, Cummings J; Department of Veterans Affairs Cooperative Study Group on Home-Based Primary Care: Effectiveness of team-managed home-based primary care: A randomized multicenter trial. JAMA 2000;284:2877-2885.
116. Ram FS, Wedzicha JA, Wright J, Greenstone M: Hospital at home for patients with acute exacerbations of chronic obstructive pulmonary disease: Systematic review of evidence. BMJ 2004;329:315.
117. Hermiz O, Comino E, Marks G, Daffurn K, Wilson S, Harris M: Randomised controlled trial of home based care of patients with chronic obstructive pulmonary disease. BMJ 2002;325:938.
118. Kwok T, Lum CM, Chan HS, Ma HM, Lee D, Woo J: A randomized, controlled trial of an intensive community nurse-supported discharge program in preventing hospital readmissions of older patients with chronic lung disease. J Am Geriatr SoC 2004;52:1240-1246.
119. Rabow MW, Dibble SL, Pantilat SZ, McPhee SJ. The comprehensive care team: A controlled trial of outpatient palliative medicine consultation. Arch Intern Med. 2004; 164:83-91.
120. Aiken LS, Butner J, Lockhart CA, Volk-Craft BE, Hamilton G, Williams FG: Outcome evaluation of a randomized trial of the PhoenixCare intervention: Program of case management and coordinated care for the seriously chronically ill. J Palliat Med 2006;9:111-126.
121. Keenan SP, Sinuff T, Cook DJ, Hill NS: Which patients with acute exacerbation of chronic obstructive pulmonary disease benefit from noninvasive positive-pressure ventilation? A systematic review of the literature. Ann Intern Med 2003;138:861-870.
122. Benhamou D, Girault C, Faure C, Portier F, Muir JF: Nasal mask ventilation in acute respiratory failure. Experience in elderly patients. Chest 1992;102:912-917.
123. Meduri GU, Fox RC, Abou-Shala N, Leeper KV, Wunderink RG: Noninvasive mechanical ventilation via face mask in patients with acute respiratory failure who refused endotracheal intubation. Crit Care Med 1994;22:1584-1590.
124. Benditt JO. Noninvasive ventilation at the end of life. Respir Care 2000;45:1376-1381; discussion 1381-1384.
125. Sinuff T, Adhikari NKJ, Geerts S, Curtis JR, Cook DJ, Keenan SP, Hill NS. Noninvasive Ventilation (NIV) for Patients with Acute Respiratory Failure (ARF) in the Setting of a Do-not-intubate (DNI) Decision: Systematic Review. Proceedings of the American Thoracic Society 2007;147:A787.
126. Schettino G, Altobelli N, Kacmarek RM: Noninvasive positive pressure ventilation reverses acute respiratory failure in select "do-not- intubate" patients. Crit Care Med 2005;33:1976-1982.
127. Levy M, Tanios MA, Nelson D, Short K, Senechia A, Vespia J, Hill NS: Outcomes of patients with do-not-intubate orders treated with noninvasive ventilation. Crit Care Med 2004;32:2002-2007.
128. Chu CM, Chan VL, Wong IW, Leung WS, Lin AW, Cheung KF: Noninvasive ventilation in patients with acute hypercapnic exacerbation of chronic obstructive pulmonary disease who refused endotracheal intubation. Crit Care Med 2004;32:372-377.
129. Sinuff T, Burns KEA, Eva K, Adhikari NKJ, Keenan SP, Rocker G, Hill N, Patel R, Mehta S, Heels-Ansdell D, Heyland D, Kacmarek R, Cook DJ. Noninvasive ventilation (NIV) for acute respiratory failure (ARF) near the end-of-life (EOL). Proc Am Thorac Soc 2005;2:A810.