Pneumocystis jiroveci pneumonia (PCP) in HIV-1-negative patients: A retrospective study 2002-2004

Scandinavian Journal of Infectious Diseases

Volumn 39, Issue 6-7, 2007, Pages 589-595

  Overgaard, Ulrik M ^a   Helweg Larsen, Jannik ^a  

^a Rigshospitalet   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; ANTINEOPLASTIC AGENT; BLEOMYCIN; CHLORAMBUCIL; CISPLATIN; COTRIMOXAZOLE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; CYTARABINE; DACARBAZINE; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; FLUDARABINE; GAMMA INTERFERON; HYDROXYUREA; IMATINIB; IMMUNOSUPPRESSIVE AGENT; MELPHALAN; MERCAPTOPURINE; METHOTREXATE; MITOXANTRONE; PREDNISOLONE; PROCARBAZINE; RITUXIMAB; STEROID; UNINDEXED DRUG; VINBLASTINE; VINCRISTINE; VINCRISTINE SULFATE;

ADOLESCENT; ADULT; ARTICLE; CD4 LYMPHOCYTE COUNT; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DELAYED DIAGNOSIS; DENMARK; DISEASE PREDISPOSITION; DRUG DOSE REDUCTION; DRUG EXPOSURE; DRUG PULSE THERAPY; DRUG USE; DRUG WITHDRAWAL; HEMATOLOGIC MALIGNANCY; HIGH RISK POPULATION; HISTOPATHOLOGY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE DEFICIENCY; IMMUNOCOMPROMISED PATIENT; INCIDENCE; INFANT; INFECTION PREVENTION; INFECTION RISK; INFLAMMATORY DISEASE; LYMPHOCYTOPENIA; MORTALITY; ORGAN TRANSPLANTATION; PNEUMOCYSTIS JIROVECI; PNEUMOCYSTIS PNEUMONIA; POLYMERASE CHAIN REACTION; RETROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; THERAPY DELAY;

ADOLESCENT; ADULT; CD4 LYMPHOCYTE COUNT; CD4-POSITIVE T-LYMPHOCYTES; CHILD; CHILD, PRESCHOOL; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; INFANT; MALE; MIDDLE AGED; PNEUMOCYSTIS JIROVECI; PNEUMONIA, PNEUMOCYSTIS; POLYMERASE CHAIN REACTION; RETROSPECTIVE STUDIES; RISK FACTORS; TREATMENT OUTCOME;

EID: 34347366251     PISSN: 00365548     EISSN: 16511980     Source Type: Journal    
DOI: 10.1080/00365540601150497     Document Type: Article

References (23)

1. Mocroft, A., Katlama, C., Johnson, AM, Pradier, C., Antunes, F. and Mulcahy, F. (2000) AIDS across Europe, 1994-98: The EuroSIDA study. Lancet, 356, pp. 291-296.
2. Mahindra, AK and Grossman, SA. (2003) Pneumocystis carinii pneumonia in HIV-negative patients with primary brain tumours. J Neurooncol, 63, pp. 263-270.
3. Nuesch, R., Bellini, C. and Zimmerli, W. (1999) Pneumocystis carinii pneumonia in human immunodeficiency virus (HIV)-positive and HIV-negative immunocompromized patients. Clin Infect Dis, 29, pp. 1519-1523.
4. Arend, SM, Kroon, FP and Wout, JW. Van't (1995) Pneumocystis carinii pneumonia in patients without AIDS, 1980 through 1993. Archives of Internal Medicine, 155, pp. 2436-2441.
5. Kovacs, JA, Hiemenz, JW, Macher, AM, Stover, D., Murray, HW and Shelhamer, J. (1984) Pneumocystis carinii pneumonia: A comparison between patients with the acquired immunodeficiency syndrome and patients with other immunodeficiencies. Ann Intern Med, 100, pp. 663-671.
6. Ewig, S., Bauer, T., Schneider, C., Pickenhain, A., Pizzulli, L., Loos, U. and Luderitz, B. (1995) Clinical characteristics and outcome of Pneumocystis carinii pneumonia in HIV-infected and otherwise immunosuppressed patients. Eur Respir J, 8, pp. 1548-1553.
7. Sepkowitz, KA, Brown, AE and Armstrong, D. (1995) Pneumocystis carinii pneumonia without acquired immunodeficiency syndrome. More patients, same risk. Arch Intern Med, 155, pp. 1125-1128.
8. Helweg-Larsen, J., Skov, JJ, Dohn, B., Benfield, TL and Lundgren, B. (2002) Detection of Pneumocystis DNA in samples from patients suspected of bacterial pneumonia: A case-control study. BMC Infect Dis, 2, p. 28.
9. Pagano, L., Fianchi, L., Mele, L., Girmenia, C., Offidani, M. and Ricci, P. (2002) Pneumocystis carinii pneumonia in patients with malignant haematological diseases: 10 y' experience of infection in GIMEMA centres. Br J Haematol, 117, pp. 379-386.
10. Roblot, F., Godet, C., Moal, G Le, Garo, B., Faouzi, SM and Dary, M. (2002) Analysis of underlying diseases and prognosis factors associated with Pneumocystis carinii pneumonia in immunocompromized HIV-negative patients. Eur J Clin Microbiol Infect Dis, 21, pp. 523-531.
11. Mansharamani, NG, Balachandran, D., Vernovsky, I., Garland, R. and Koziel, H. (2000) Peripheral blood CD4+ T-lymphocyte counts during Pneumocystis carinii pneumonia in immunocompromized patients without HIV infection. Chest, 118, pp. 712-720.
12. Roblot, F., Imbert, S., Godet, C., Kauffmann, C., Ragot, S. and Moal, G Le (2004) Risk factors analysis for Pneumocystis jiroveci pneumonia (PCP) in patients with haematological malignancies and pneumonia. Scand J Infect Dis, 36, pp. 848-854.
13. Godeau, B., Coutant-Perronne, V., Thi, HD Le, Guillevin, L., Magadur, G. and De Bandt, M. (1994) Pneumocystis carinii pneumonia in the course of connective tissue disease: Report of 34 cases. J Rheumatol, 21, pp. 246-251.
14. Saksasithon, S., Sungkanuparph, S. and Thanakitcharu, S. (2003) Pneumocystis carinii pneumonia in patients without HIV infection. J Med Assoc Thai, 86, pp. 612-616.
15. Ribes, JA, Limper, AH, Espy, MJ and Smith, TF. (1997) PCR detection of Pneumocystis carinii in bronchoalveolar lavage specimens: Analysis of sensitivity and specificity. J Clin Microbiol, 35, pp. 830-835.
16. Leigh, TR, Gazzard, BG, Rowbottom, A. and Collins, JV. (1993) Quantitative and qualitative comparison of DNA amplification by PCR with immunofluorescence staining for diagnosis of Pneumocystis carinii pneumonia. J Clin Pathol, 46, pp. 140-144.
17. Sing, A., Trebesius, K., Roggenkamp, A., Russmann, H., Tybus, K. and Pfaff, F. (2000) Evaluation of diagnostic value and epidemiological implications of PCR for Pneumocystis carinii in different immunosuppressed and immunocompetent patient groups. J Clin Microbiol, 38, pp. 1461-1467.
18. Flori, P., Bellete, B., Durand, F., Raberin, H., Cazorla, C. and Hafid, J. (2004) Comparison between real time PCR, conventional PCR and different staining techniques for diagnosing Pneumocystis jiroveci pneumonia from bronchoalveolar lavage specimens. J Med Microbiol, 53, pp. 603-607.
19. Weig, M., Klinker, H., Bogner, BH, Meier, A. and Gross, U. (1997) Usefulness of PCR for diagnosis of Pneumocystis carinii pneumonia in different patient groups. J Clin Microbiol, 35, pp. 1445-1449.
20. Olsson, M., Stralin, K. and Holmberg, H. (2001) Clinical significance of nested polymerase chain reaction and immunofluorescence for detection of Pneumocystis carinii pneumonia. Clin Microbiol Infect, 7, pp. 492-497.
21. Visconti, E., Marinaci, S., Zolfo, M., Mencarini, P., Tamburrini, E. and Pagliari, G. (2000) Very low frequence of Pneumocystis carinii DNA detection by PCR in specimens from patients with lung damage. J Clin Microbiol, 38, pp. 1307-1308.
22. Glück, T., Geerdes-Fenge, HF, Straub, RH, Raffenberg, M., Lang, B. and Lode, H. (2000) Pneumocystis carinii pneumonia as a complication of immunosuppressive therapy. Infection, 28, pp. 227-230.
23. Vavricka, SR, Halter, J., Hechelhammer, L. and Himmelmann, A. (2004) Pneumocystis carinii pneumonia in chronic lymphocytic leukaemia Postgrad Med J, 80, pp. 236-238.