Assessment of NMDA receptor activation in vivo by Fos induction after challenge with the direct NMDA agonist (tetrazol-5-yl)glycine: Effects of clozapine and haloperidol

Journal of Neural Transmission

Volumn 114, Issue 7, 2007, Pages 899-908

  Inada, K ^a   Farrington, J S ^a   Moy, S S ^a   Koller, B H ^a   Duncan, G E ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Antipsychotic drugs; Clozapine; Glutamate; Haloperidol; Hippocampus; Mice; Schizophrenia

Indexed keywords

(TETRAZOL 5 YL)GLYCINE; CLOZAPINE; DIZOCILPINE; DOPAMINE 2 RECEPTOR; HALOPERIDOL; IMIPRAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR STIMULATING AGENT; PROTEIN FOS; PROTEIN SUBUNIT; TETRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; GENETICS; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CLOZAPINE; GLYCINE; HALOPERIDOL; HIPPOCAMPUS; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, KNOCKOUT; MICE, TRANSGENIC; N-METHYLASPARTATE; PROTO-ONCOGENE PROTEINS C-FOS; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; TETRAZOLES;

EID: 34347353103     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-007-0628-5     Document Type: Article

References (47)

1. Z Abdul-Monim GP Reynolds JC Neill 2006 The effect of atypical and classical antipsychotics on sub-chronic PCP-induced cognitive deficits in a reversal-learning paradigm Behav Brain Res 169 263 273
2. VL Arvanov RY Wang 1999 Clozapine, but not haloperidol, prevents the functional hyperactivity of N-methyl-D-aspartate receptors in rat cortical neurons induced by subchronic administration of phencyclidine J Pharmacol Exp Ther 289 1000 1006
3. VL Arvanov X Liang J Schwartz S Grossman RY Wang 1997 Clozapine and haloperidol modulate N-methyl-D-aspartate- and non-N-methyl-D-aspartate receptor-mediated neurotransmission in rat prefrontal cortical neurons in vitro J Pharmacol Exp Ther 283 226 234
4. VP Bakshi MA Geyer 1995 Antagonism of phencyclidine-induced deficits in prepulse inhibition by the putative atypical antipsychotic olanzapine Psychopharmacology 122 198 201
5. VP Bakshi NR Swerdlow MA Geyer 1994 Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response J Pharmacol Exp Ther 271 787 794
6. G Bustos J Abarca MI Forray K Gysling CW Bradberry RH Roth 1992 Regulation of excitatory amino acid release by N-methyl-D-aspartate receptors in rat striatum: in vivo microdialysis studies Brain Res 585 105 115
7. R Corbett F Camacho AT Woods LL Kerman RJ Fishkin K Brooks RW Dunn 1995 Antipsychotic agents antagonize non-competitive N-methyl-D-aspartate antagonist-induced behaviors Psychopharmacology 120 67 74
8. M Dragunow RLM Faull 1990 Mk-801 induces C-Fos protein in thalamic and neocortical neurons of rat-brain Neurosci Lett 111 39 45
9. GE Duncan KB Johnson GRT Breese 1993 Topographic patterns of brain activity in response to swim stress: assessment by 2-deoxyglucose uptake and expression of Fos-like immunoreactivity J Neurosci 13 3932 3943
10. GE Duncan JN Leipzig RB Mailman JA Lieberman 1998a Differential effects of clozapine and haloperidol on ketamine-induced brain metabolic activation Brain Res 812 65 75
11. GE Duncan SS Moy DJ Knapp RA Mueller GR Breese 1998b Metabolic mapping of the rat brain after subanesthetic doses of ketamine: potential relevance to schizophrenia Brain Res 787 181 190
12. GE Duncan S Miyamoto JN Leipzig JA Lieberman 1999a Comparison of brain metabolic activity patterns induced by ketamine, MK-801 and amphetamine in rats: support for NMDA receptor involvement in responses to subanesthetic dose of ketamine Brain Res 843 171 183
13. GE Duncan S Zorn JA Lieberman 1999b Mechanisms of typical and atypical antipsychotic drug action in relation to dopamine and NMDA receptor hypofunction hypotheses of schizophrenia Mol Psychiat 4 418 428
14. GE Duncan S Miyamoto JN Leipzig JA Lieberman 2000 Comparison of the effects of clozapine, risperidone, and olanzapine on ketamine-induced alterations in regional brain metabolism J Pharmacol Exp Ther 293 8 14
15. GE Duncan S Miyamoto HB Gu JA Lieberman BH Koller JN Snouwaert 2002 Alterations in regional brain metabolism in genetic and pharmacological models of reduced NMDA receptor function Brain Res 951 166 176
16. GE Duncan SS Moy A Perez DM Eddy WM Zinzow JA Lieberman JN Snouwaert BH Koller 2004 Deficits in sensorimotor gating and tests of social behavior in a genetic model of reduced NMDA receptor function Behav Brain Res 153 507 519
17. GE Duncan SS Moy JA Lieberman BH Koller 2006 Effects of haloperidol, clozapine, and quetiapine on sensorimotor gating in a genetic model of reduced NMDA receptor function Psychopharmacology 184 190 200
18. NB Farber MT Price J Labruyere J Nemnich H St. Peter DF Wozniak JW Olney 1993 Antipsychotic drugs block phencyclidine receptor-mediated neurotoxicity Biol Psychiat 34 119 121
19. NB Farber SH Kim K Dikranian XP Jiang C Heinkel 2002 Receptor mechanisms and circuitry underlying NMDA antagonist neurotoxicity Mol Psychiat 7 32 43
20. RL Fradley GF O'Meara RJ Newman A Andrieux D Job DS Reynolds 2005 STOP knockout and NMDA NR1 hypomorphic mice exhibit deficits in sensorimotor gating Behav Brain Res 163 257 264
21. KBJ Franklin G Paxinos 1997 The mouse brain in stereotaxic coordinates Academic Press San Diego
22. R Greene 2001 Circuit analysis of NMDAR hypofunction in the hippocampus, in vitro, and psychosis of schizophrenia Hippocampus 11 569 577
23. HC Grunze DG Rainnie ME Hasselmo E Barkai EF Hearn RW McCarley RW Greene 1996 NMDA-dependent modulation of CA1 local circuit inhibition J Neurosci 16 2034 2043
24. U Heresco-Levy 2003 Glutamatergic neurotransmission modulation and the mechanisms of antipsychotic atypicality Prog Neuro psychopharmacol Biol Psychiat 27 1113 1123
25. DC Javitt SR Zukin 1991 Recent advances in the phencyclidine model of schizophrenia Am J Psychiat 148 1301 1308
26. S Kapur SC Vanderspek BA Brownlee JN Nobrega 2003 Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition: a suggested solution based on in vivo occupancy J Pharmacol Exp Ther 305 625 631
27. JH Krystal LP Karper JP Seibyl GK Freeman R Delaney JD Bremner GR Heninger MB Bowers Jr DS Charney 1994 Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses Arch Gen Psychiat 51 199 214
28. A Kurumaji DG Nehls CK Park J McCulloch 1989 Effects of NMDA antagonists, MK-801 and CPP, upon local cerebral glucose use Brain Res 496 268 284
29. AC Lahti B Koffel D LaPorte CA Tamminga 1995 Subanesthetic doses of ketamine stimulate psychosis in schizophrenia Neuropsychopharmacology 13 9 19
30. AC Lahti MA Weiler MB Tamara A Parwani CA Tamminga 2001 Effects of ketamine in normal and schizophrenic volunteers Neuropsychopharmacology 25 455 467
31. DS Lorrain CS Baccei LJ Bristow JJ Anderson MA Varney 2003 Effects of ketamine and N-methyl-D-aspartate on glutamate and dopamine release in the rat prefrontal cortex: modulation by a group II selective metabotropic glutamate receptor agonist LY379268 Neuroscience 117 697 706
32. WHW Lunn DD Schoepp DO Calligaro RT Vasileff LJ Heinz CR Salhoff PJ Omalley 1992 Dl-tetrazol-5-ylglycine, a highly potent NMDA agonist - its synthesis and NMDA receptor efficacy J Med Chem 35 4608 4612
33. S Miyamoto JN Leipzig JA Lieberman GE Duncan 2000 Effects of ketamine, MK-801, and amphetamine on regional brain 2-deoxyglucose uptake in freely moving mice Neuropsychopharmacology 22 400 412
34. S Miyamoto JN Snouwaert BH Koller SS Moy JA Lieberman GE Duncan 2004 Amphetamine-induced Fos is reduced in limbic cortical regions but not in the caudate or accumbens in a genetic model of NMDA receptor hypofunction Neuropsychopharmacology 29 2180 2188
35. B Moghaddam B Adams A Verman D Daly 1997 Activation of glutamatergic neurotransmission by ketamine - a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex J Neurosci 17 2921 2927
36. AR Mohn RR Gainetdinov MG Caron BH Koller 1999 Mice with reduced NMDA receptor expression display behaviors related to schizophrenia Cell 98 427 436
37. SS Moy A Perez BH Koller GE Duncan 2006 Amphetamine-induced disruption of prepulse inhibition in mice with reduced NMDA receptor function Brain Res 1089 186 194
38. M Nilsson KR Markinhuhta ML Carlsson 2006 Differential effects of classical neuroleptics and a newer generation antipsychotics on the MK-801 induced behavioural primitivization in mouse Prog Neuropsychopharmacol Biol Psychiat 30 521 530
39. I Ninan KE Jardemark RY Wang 2003 Differential effects of atypical and typical antipsychotic drugs on N-methyl-D-aspartate- and electrically evoked responses in the pyramidal cells of the rat medial prefrontal cortex Synapse 48 66 79
40. SY Sakurai JHJ Cha JB Penney AB Young 1991 Regional distribution and properties of [H-3] Mk-801 binding-sites determined by quantitative autoradiography in rat-brain Neuroscience 40 533 543
41. DD Schoepp CL Smith D Lodge JD Millar JD Leander AI Sacaan WHW Lunn 1991 D,L-(Tetrazol-5-Yl) Glycine - a novel and highly potent NMDA receptor agonist Eur J Pharmacol 203 237 243
42. M Sheng ME Greenberg 1990 The regulation and function of C-Fos and other immediate early genes in the nervous-system Neuron 4 477 485
43. NR Swerdlow VP Bakshi MA Geyer 1996 Seroquel restores sensorimotor gating in phencyclidine-treated rats J Pharmacol Exp Ther 279 1290 1299
44. FI Tarazi WJ Florijn I Creese 1996 Regulation of ionotropic glutamate receptors following subchronic and chronic treatment with typical and atypical antipsychotics Psychopharmacology 128 371 379
45. RY Wang X Liang 1998 M100907 and clozapine, but not haloperidol or raclopride, prevent phencyclidine-induced blockade of NMDA responses in pyramidal neurons of the rat medial prefrontal cortical slice Neuropsychopharmacology 19 74 85
46. M Wittmann MJ Marino DA Henze GR Seabrook PJ Conn 2005 Clozapine potentiation of N-methyl-D-aspartate receptor currents in the nucleus accumbens: role of NR2B and protein kinase A/Src kinases J Pharmacol Exp Ther 313 594 603
47. W Zhang FP Bymaster 1999 The in vivo effects of olanzapine and other antipsychotic agents on receptor occupancy and antagonism of dopamine D-1, D-2, D-3, 5HT(2A) and muscarinic receptors Psychopharmacology 141 267 278