Barrier qualities of the mouse eye to topically applied drugs

Experimental Eye Research

Volumn 85, Issue 1, 2007, Pages 105-112

  Wang, Zhao ^a   Do, Chi Wai ^a,b   Avila, Marcel Y ^a,c   Stone, Richard A ^a   Jacobson, Kenneth A ^d   Civan, Mortimer M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^c UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

intraocular pressure; miosis; pneumotonometer; purinergic drugs; servo null micropipette system (SNMS)

Indexed keywords

1,4 DIHYDRO 2 METHYL 6 PHENYL 4 (2 PHENYLETHYNYL) 3,5 PYRIDINEDICARBOXYLIC ACID 5 BENZYL 3 ETHYL ESTER; 2 CHLORO 6 N (3 IODOBENZYL)ADENOSINE 5' N METHYLCARBOXAMIDE; 6 N (3 IODOBENZYL)ADENOSINE 5' N METHYLCARBOXAMIDE; ADENOSINE; ADENOSINE A3 RECEPTOR; CARBACHOL; EYE DROPS; PURINERGIC RECEPTOR AFFECTING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORNEA; DRUG ABSORPTION; DRUG DIFFUSION; DRUG EFFICACY; DRUG PENETRATION; INTRAOCULAR PRESSURE; INVASIVE PROCEDURE; MICROPIPETTE; MOUSE; NONHUMAN; PERMEABILITY BARRIER; PRIORITY JOURNAL; PUPIL; SCLERA; SERVO NULL MICROPIPETTE SYSTEM; TONOMETRY;

ADENOSINE; ADMINISTRATION, TOPICAL; ANIMALS; CARBACHOL; CORNEA; DIHYDROPYRIDINES; EYE; FEMALE; INTRAOCULAR PRESSURE; MALE; MICE; MIOTICS; PUPIL; RECEPTOR, ADENOSINE A3; SCLERA; TONOMETRY, OCULAR; VASODILATOR AGENTS;

EID: 34347337552     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2007.03.006     Document Type: Article

References (29)

1. The AGIS investigators. The Advanced Glaucoma Intervention Study (AGIS): 7, 2000. The relationship between control of intraocular pressure and visual field deterioration. Am. J. Ophthalmol 130 (2000) 429-440
2. Aihara M., Lindsey J.D., and Weinreb R.N. Reduction of intraocular pressure in mouse eyes treated with latanoprost. Invest. Ophthalmol. Vis. Sci. 43 (2002) 146-150
3. Avila M.Y., Carré D.A., Stone R.A., and Civan M.M. Reliable measurement of mouse intraocular pressure by a servo-null micropipette system. Invest. Ophthalmol. Vis. Sci. 42 (2001) 1841-1846
4. 3-Subtype adenosine receptors modulate intraocular pressure in the mouse. Br. J. Pharmacol 134 (2001) 241-245
5. 3 adenosine receptors reduces mouse intraocular pressure. Invest. Ophthalmol. Vis. Sci. 43 (2002) 3021-3026
6. Avila M.Y., Seidler R.W., Stone R.A., and Civan M.M. Inhibitors of NHE-1 Na+/H+ exchange reduce mouse intraocular pressure. Invest. Ophthalmol. Vis. Sci. 43 (2002) 1897-1902
7. Avila M.Y., Múnera A., Guzmán A., Wang Z., Do C.W., Stone R.A., and Civan M.M. Non-invasive intraocular pressure measurements in mice by pneumotonometry. Invest. Ophthalmol. Vis. Sci. 46 (2005) 3274-3280
8. - channels of nonpigmented ciliary epithelial cells. Am. J. Physiol. Cell Physiol 273 (1997) C1354-C1361
9. Carré D.A., Mitchell C.H., Peterson-Yantorno K., Coca-Prados M., and Civan M.M. Similarity of A(3)-adenosine and swelling-activated Cl(-) channels in nonpigmented ciliary epithelial cells. Am. J. Physiol. Cell Physiol 279 (2000) C440-C451
10. Cass C.E., Young J.D., and Baldwin S.A. Recent advances in the molecular biology of nucleoside transporters of mammalian cells. Biochem. Cell Biol. 76 (1998) 761-770
11. Collaborative Normal-Tension Glaucoma Study Group. Comparison of glaucomatous progression between untreated patients with normal-tension glaucoma and patients with therapeutically reduced intraocular pressures. Am. J. Ophthalmol 126 (1998) 487-497
12. Collaborative Normal-Tension Glaucoma Study Group. The effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucoma. Am. J. Ophthalmol 126 (1998) 498-505
13. Fleischhauer J.C., Mitchell C.H., Stamer W.D., Karl M.O., Peterson-Yantorno K., and Civan M.M. Common actions of adenosine receptor agonists in modulating human trabecular meshwork cell transport. J. Membr. Biol. 193 (2003) 121-136
14. Fredholm B.B., Irenius E., Kull B., and Schulte G. Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells. Biochem. Pharmacol 61 (2001) 443-448
15. Gao Z.G., Kim S.K., Biadatti T., Chen W., Lee K., Barak D., Kim S.G., Johnson C.R., and Jacobson K.A. Structural determinants of A3 adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary. J. Med. Chem. 45 (2002) 4471-4484
16. Griffith D.A., and Jarvis S.M. Nucleoside and nucleobase transport systems of mammalian cells. Biochim. Biophys. Acta 1286 (1996) 153-181
17. Grimes P.A., Stone R.A., Laties A.M., and Li W. Carboxyfluorescein. A probe of the blood-ocular barriers with lower membrane permeability than fluorescein. Arch. Ophthalmol 100 (1982) 635-639
18. Husain S., Whitlock N.A., Rice D.S., and Crosson C.E. Effects of latanoprost on rodent intraocular pressure. Exp. Eye Res. 83 (2006) 1453-1458
19. 3 adenosine receptor-selective antagonists. Neuropharmacology 36 (1997) 1157-1165
20. Jester J.V., Lee Y.G., Li J., Chakravarti S., Paul J., Petroll W.M., and Cavanagh H.D. Measurement of corneal sublayer thickness and transparency in transgenic mice with altered corneal clarity using in vivo confocal microscopy. Vision Res. 41 (2001) 1283-1290
21. Karl M.O., Fleischhauer J.C., Stamer W.D., Peterson-Yantorno K., Mitchell C.H., Stone R.A., and Civan M.M. Differential P1-purinergic modulation of human Schlemm's canal inner-wall cells. Am. J. Physiol. Cell Physiol 288 (2005) C784-C794
22. Majumdar S., Gunda S., and Mitra A.K. Functional expression of a sodium dependent nucleoside transporter on rabbit cornea: Role in corneal permeation of acyclovir and idoxuridine. Curr. Eye Res. 26 (2003) 175-183
23. - channels of nonpigmented ciliary epithelial cells. Am. J. Physiol. Cell Physiol 276 (1999) C659-C666
24. Pang I.H., Wang W.H., and Clark A.F. Acute effects of glaucoma medications on rat intraocular pressure. Exp. Eye Res. 80 (2005) 207-214
25. Quigley H.A. Number of people with glaucoma worldwide. Br. J. Ophthalmol 80 (1996) 389-393
26. Reitsamer H.A., Kiel J.W., Harrison J.M., Ransom N.L., and McKinnon S.J. Tonopen measurement of intraocular pressure in mice. Exp. Eye Res. 78 (2004) 799-804
27. Schoenwald R.D. Ocular Pharmacokinetics. In: Zimmerman T., Kooner K., and Sharir M. (Eds). Textbook of Ocular Pharmacology (1997), Lippincott-Raven Press, Philadelphia, PA 119-138
28. 6-disubstituted adenine nucleosides as highly potent and selective A3 adenosine receptor agonists. J. Med. Chem. 48 (2005) 1745-1758
29. Wang, Z., Do, C.W., Avila, M.Y., Stone, R.A., Civan, M.M., 2006. Refinements of invasive and non-invasive mouse intraocular pressure measurements (letter). Invest. Ophthalmol. Vis. Sci. (serial online). Available at http://www.iovs.org/cgi/eletters/46/9/3274#422. Accessed on August 31, 2006.