Interferon-gamma and interleukin-4 gene polymorphisms in Caucasian idiopathic inflammatory myopathy patients in UK

Annals of the Rheumatic Diseases

Volumn 66, Issue 7, 2007, Pages 970-973

  Chinoy, Hector ^a   Salway, Fiona ^a   John, Sally ^a   Fertig, Noreen ^b   Tait, Brian D ^c   Oddis, Chester V ^b   Ollier, William E R ^a   Cooper, Robert G ^a,d  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c Australian Red Cross   (Australia)

^d HOPE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HLA ANTIGEN CLASS 2; INTERLEUKIN 4; RIBONUCLEOPROTEIN;

ADULT; ALLELE; ARTICLE; CAUCASIAN; CONFIDENCE INTERVAL; CONNECTIVE TISSUE DISEASE; CONTROLLED STUDY; DERMATOMYOSITIS; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; IDIOPATHIC DISEASE; INTRON; MAJOR CLINICAL STUDY; MICROSATELLITE MARKER; MYOSITIS; POLYMYOSITIS; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED KINGDOM;

ADULT; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; DERMATOMYOSITIS; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GREAT BRITAIN; HLA ANTIGENS; HUMANS; INTERFERON TYPE II; INTERLEUKIN-4; LINKAGE DISEQUILIBRIUM; MICROSATELLITE REPEATS; MYOSITIS; POLYMORPHISM, SINGLE NUCLEOTIDE; POLYMYOSITIS;

EID: 34347263366     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.2006.068858     Document Type: Article

References (15)

1. Chinoy H, Ollier WE, Cooper RG. Have recent immunogenetic investigations increased our understanding of disease mechanisms in the idiopathic inflammatory myopathies? Curr Opin Rheumatol 2004;16:707-13.
2. O'Hanlon TP, Carrick DM, Arnett FC, Reveille JD, Carrington M, Gao X, et al. Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1 and -DQA1 allelic profiles and motifs define clinicopathologic groups in Caucasians. Medicine (Baltimore) 2005;84:338-49.
3. Chinoy H, Salway F, Fertig N, Shephard N, Tait BD, Thomson W, et al. In adult onset myositis, the presence of interstitial lung disease and myositis specific/ associated antibodies are governed by HLA class II haplotype, rather than by myositis subtype. Arthritis Res Ther 2006;8:R13.
4. Vandenbroeck K, Goris A. Cytokine gene polymorphisms in multifactorial diseases: gateways to novel targets for immunotherapy? Trends Pharmacol Sci 2003;24:284-9.
5. Figarella-Branger D, Civatte M, Bartoli C, Pellissier JF. Cytokines, chemokines, and cell adhesion molecules in inflammatory myopathies. Muscle Nerve 2003;28:659-82.
6. Lundberg I, Ulfgren AK, Nyberg P, Andersson U, Klareskog L. Cytokine production in muscle tissue of patients with idiopathic inflammatory myopathies. Arthritis Rheum 1997;40:865-74.
7. Adams EM, Kirkley J, Eidelman G, Dohlman J, Plotz PH. The predominance of beta (CC) chemokine transcripts in idiopathic inflammatory muscle diseases. Proc Assoc Am Physicians 1997;109:275-85.
8. Lepidi H, Frances V, Figarella-Branger D, Bartoli C, Machado-Baeta A, Pellissier JF. Local expression of cytokines in idiopathic inflammatory myopathies. Neuropathol Appl Neurobiol 1998;24:73-9.
9. Megens-de Letter MA, Visser LH, van Doom PA, Savelkoul HF. Cytokines in the muscle tissue of idiopathic inflammatory myopathies: implications for immunopathogenesis and therapy. Eur Cytokine Netw 1999;10:471-8.
10. Bohan A, Peter JB. Polymyositis and dermatomyositis (first of two parts). N Engl J Med 1975;292:344-7.
11. Pravica V, Asderakis A, Perrey C, Hajeer A, Sinnott PJ, Hutchinson IV. In vitro production of IFN-gamma correlates with CA repeat polymorphism in the human IFN-gamma gene. Eur J Immunogenet 1999;26:1-3.
12. Chinoy H, Salway F, Fertig N, Tait BD, Oddis CV, Ollier WE, et al. Monocyte chemotactic protein-1 single nucleotide polymorphisms do not confer susceptibility for the development of adult onset polymyositis/ dermatomyositis in UK Caucasians. Rheumatology (Oxford) 2007;46:604-7.
13. Lee JY, Goldman D, Piliero LM, Petri M, Sullivan KE. Interferon-gamma polymorphisms in systemic lupus erythematosus. Genes Immun 2001;2:254-7.
14. Gonzalez-Gay MA, Hajeer AH, Dababneh A, Garcia-Porrua C, Amoli MM, Llorca J, et al. Interferon-gamma gene microsatellite polymorphisms in patients with biopsy-proven giant cell arteritis and isolated polymyalgia rheumatica. Clin Exp Rheumatol 2004;22:S18-S20.
15. Miyake K, Nakashima H, Akahoshi M, Inoue Y, Nagano S, Tanaka Y, et al. Genetically determined interferon-(gamma) production influences the histological phenotype of lupus nephritis. Rheumatology 2002;41:518-24.