Predictive Value of Microvolt T-Wave Alternans in Patients With Left Ventricular Dysfunction

Journal of the American College of Cardiology

Volumn 50, Issue 2, 2007, Pages 166-173

  Cantillon, Daniel J ^a   Stein, Kenneth M ^a   Markowitz, Steven M ^a   Mittal, Suneet ^a   Shah, Bindi K ^a   Morin, Daniel P ^a   Zacks, Eran S ^a   Janik, Matthew ^a   Ageno, Shaun ^a   Mauer, Andreas C ^a   Lerman, Bruce B ^a   Iwai, Sei ^a  

^a WEILL CORNELL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; DEFIBRILLATOR; ELECTROPHYSIOLOGY; FEMALE; HEART ARRHYTHMIA; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE ISCHEMIA; HEART VENTRICLE TACHYCARDIA; HUMAN; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALE; MORTALITY; PREDICTION; PRIORITY JOURNAL; PROPHYLAXIS; PROSPECTIVE STUDY; RISK ASSESSMENT; SURVIVAL; SYNCOPE; T WAVE;

AGED; ANALYSIS OF VARIANCE; ARRHYTHMIA; DEATH, SUDDEN, CARDIAC; DISEASE-FREE SURVIVAL; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; FEMALE; HUMANS; KAPLAN-MEIERS ESTIMATE; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; OBSERVATION; PROGNOSIS; PROSPECTIVE STUDIES; RISK ASSESSMENT; STROKE VOLUME; VENTRICULAR DYSFUNCTION, LEFT;

EID: 34347253892     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2007.02.069     Document Type: Article

References (21)

1. Zheng Z.J., Croft J.B., Giles W.H., and Mensah G.A. Sudden cardiac death in the United States, 1989 to 1998. Circulation 104 (2001) 2158-2163
2. Smith J.M., Clancy E., Valeri C., Ruskin J., and Cohen R. Electrical alternans and cardiac electrical instability. Circulation 108 (2003) 1779-1783
3. Rosenbaum D.S., Jackson L.E., Smith J.M., Garan H., Ruskin J.N., and Cohen R.J. Electrical alternans and vulnerability to ventricular arrhythmias. N Engl J Med 330 (1994) 235-241
4. Hohnloser S.H., Klingenheben T., Li Y.G., et al. T-Wave alternans as a predictor of recurrent ventricular tachyarrhythmias in ICD recipients: prospective comparison with conventional risk markers. J Cardiovasc Electrophysiol 9 (1998) 1258-1268
5. Gold M.R., Bloomfield D.M., Anderson K.P., et al. A comparison of T-wave alternans, signal averaged electrocardiography and programmed ventricular stimulation for arrhythmia risk stratification. J Am Coll Cardiol 36 (2000) 2247-2253
6. Bardy G.H., Lee K.L., Mark D.B., et al. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. N Engl J Med 352 (2005) 225-237
7. Moss A.J., Zareba W., Hall W.J., et al. Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N Engl J Med 346 (2002) 877-883
8. Bigger J.T. Expanding indications for implantable cardiac defibrillators. N Engl J Med 346 (2002) 931-933
9. Reynolds M.R., and Josephson M.E. MADIT II debate: risk stratification, costs and public policy. Circulation 108 (2003) 1779-1783
10. Chan P.S., Stein K.M., Chow T., Fendrick M., Bigger J.T., and Vijan S. Cost-effectiveness of a microvolt T-wave alternans screening strategy for implantable cardioverter-defibrillator placement in the MADIT-II-eligible population. J Am Coll Cardiol 48 (2006) 112-121
11. Moss A.J., Hall W.J., Cannom D.S., et al. Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia. N Engl J Med 335 (1996) 1933-1940
12. Buxton A., Lee K.L., DiCarlo L., et al. Electrophysiologic testing to identify patients with coronary artery disease who are at high risk for sudden death. N Engl J Med 342 (2000) 1937-1945
13. Tanno K., Ryu S., Watanabe N., et al. Microvolt T-wave alternans as a predictor of ventricular tachyarrhythmias: a prospective study using atrial pacing. Circulation 109 (2004) 1854-1858
14. Bloomfield D., Hohnloser S., and Cohen R. Interpretation and classification of microvolt T wave alternans test. J Cardiovasc Electrophysiol 13 (2002) 502-512
15. Kaufman E.S., Bloomfield D.M., Steinman R.C., et al. "Indeterminate" microvolt T-wave alternans tests predict high risk of death or sustained ventricular arrhythmias in patients with left ventricular dysfunction. J Am Coll Cardiol 48 (2006) 1399-1404
16. Bloomfield D.M., Bigger J.T., Steinman R.C., et al. Microvolt T-wave alternans and the risk of death or sustained ventricular arrhythmias in patients with left ventricular dysfunction. J Am Coll Cardiol 47 (2006) 456-463
17. Chow T., Kereiakes D.J., Bartone C., et al. Prognostic utility of microvolt T-wave alternans in risk stratification of patients with ischemic cardiomyopathy. J Am Coll Cardiol 47 (2006) 1820-1827
18. Bloomfield D.M., Steinman R.C., Namerow P.B., et al. Microvolt T-wave alternans distinguishes between patients likely and patients not likely to benefit from implanted cardiac defibrillator therapy. Circulation 110 (2004) 1885-1889
19. Hohnloser S.H., Klingenheben T., Bloomfield D., Dabbous O., and Cohen R.J. Usefulness of microvolt T-wave alternans for prediction of ventricular tachyarrhythmic events in patients with dilated cardiomyopathy: results from a prospective observational study. J Am Coll Cardiol 41 (2003) 2220-2224
20. Rashba E.J., Osman A.F., MacMurdy K., et al. Enhanced detection of arrhythmia vulnerability using T wave alternans, left ventricular ejection fraction, and programmed ventricular stimulation: a prospective study in subjects with chronic ischemic heart disease. J Cardiovasc Electrophysiol 15 (2004) 170-176
21. Rashba E.J., Osman A.F., MacMurdy K., et al. Exercise is superior to pacing for T wave alternans measurement in subjects with chronic coronary artery disease and left ventricular dysfunction. J Cardiovasc Electrophysiol 13 (2002) 845-850