Extra-pancreatic insulin production in RAt lachrymal gland after streptozotocin-induced islet β-cells destruction

Biochimica et Biophysica Acta - General Subjects

Volumn 1770, Issue 8, 2007, Pages 1128-1135

  Andrade Cunha, Daniel ^a   de Alves, Mônica C ^a   Stoppiglia, Luiz Fabrizio ^a   Jorge, Angélica Gobbi ^b   Módulo, Carolina Maria ^b   Carneiro, Everardo M ^a   Boschero, Antonio C ^a   Saad, Mário J A ^a   Velloso, Lício A ^a   Rocha, Eduardo M ^a,b  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Diabetes mellitus; Dry eye; Extra pancreatic; Hormone peptides; Insulin; Lachrymal gland; Reactive oxygen species; Tears

Indexed keywords

C PEPTIDE; CARBACHOL; GLUCOSE; INSULIN; PEROXIDASE; REACTIVE OXYGEN METABOLITE;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CHEMICAL ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INSULIN RELEASE; INSULIN SYNTHESIS; LACRIMAL FLUID; LACRIMAL GLAND; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES;

ANIMALS; CARBACHOL; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSE; IMMUNOHISTOCHEMISTRY; INSULIN; ISLETS OF LANGERHANS; LACRIMAL APPARATUS; MALE; PANCREAS; PEROXIDASE; RATS; RATS, WISTAR; STREPTOZOCIN; SYNAPTOPHYSIN;

RATTUS; RATTUS NORVEGICUS;

EID: 34347245593     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2007.05.002     Document Type: Article

References (39)

1. Rocha E.M., Cunha D.A., Carneiro E.M., Boschero A.C., Saad M.J., and Velloso L.A. Identification of insulin in the tear film and insulin receptor and IGF-1 receptor on the human ocular surface. Invest Ophthalmol Visual Sci. 43 (2002) 963-967
2. Myers Jr. M.G., and White M.F. Insulin signal transduction and the IRS proteins. Annu. Rev. Pharmacol. Toxicol. 36 (1996) 615-658
3. Soria B., Roche E., Berna G., Leon-Quinto T., Reig J.A., and Martin F. Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice. Diabetes 49 (2000) 157-162
4. Seckl M.J., Mulholland P.J., Bishop A.E., Teale J.D., Hales C.N., Glaser M., Watkins S., and Seckl J.R. Hypoglycemia due to an insulin-secreting small-cell carcinoma of the cervix. N. Engl. J. Med. 341 (1999) 733-736
5. Rosenzweig J.L., Havrankova J., Lesniak M.A., Brownstein M., and Roth J. Insulin is ubiquitous in extrapancreatic tissues of rats and humans. Proc. Natl. Acad. Sci. U. S. A. 77 (1980) 572-576
6. Carter D.A., Wobken J.D., Dixit P.K., and Bauer G.E. Immunoreactive insulin in rat salivary glands and its dependence on age and serum insulin levels. Proc. Soc. Exp. Biol. Med. 209 (1995) 245-250
7. Assady S., Maor G., Amit M., Itskovitz-Eldor J., Skorecki K.L., and Tzukerman M. Insulin production by human embryonic stem cells. Diabetes 50 (2001) 1691-1697
8. Hernandez-Sanchez C., Mansilla A., de la Rosa E.J., Pollerberg G.E., Martinez-Salas E., and de Pablo F. Upstream AUGs in embryonic proinsulin mRNA control its low translation level. EMBO J. 22 (2003) 5582-5592
9. Eng J., and Yalow R.S. Evidence against extrapancreatic insulin synthesis. Proc. Natl. Acad. Sci. U. S. A. 78 (1981) 4576-4578
10. Rajagopal J., Anderson W.J., Kume S., Martinez O.I., and Melton D.A. Insulin staining of ES cell progeny from insulin uptake. Science 299 (2003) 363
11. Kojima H., Fujimiya M., Matsumura K., Nakahara T., Hara M., and Chan L. Extrapancreatic insulin-producing cells in multiple organs in diabetes. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 2458-2463
12. Devaskar S.U., Giddings S.J., Rajakumar P.A., Carnaghi L.R., Menon R.K., and Zahm D.S. Insulin gene expression and insulin synthesis in mammalian neuronal cells. J. Biol. Chem. 269 (1994) 8445-8454
13. Taouis M., Deville de Periere D., Hillaire-Buys D., Derouet M., Gross R., Simon J., and Ribes G. Biological activity of immunoreactive insulin-like activity extracted from rat submandibular gland. Am. J. Physiol. 269 (1995) E277-E282
14. Kojima H., Nakamura T., Fujita Y., Kishi A., Fujimiya M., Yamada S., Kudo M., Nishio Y., Maegawa H., Haneda M., Yasuda H., Kojima I., Seno M., Wong N.C., Kikkawa R., and Kashiwagi A. Combined expression of pancreatic duodenal homeobox 1 and islet factor 1 induces immature enterocytes to produce insulin. Diabetes 51 (2002) 1398-1408
15. Cunha D.A., Carneiro E.M., Alves Mde C., Jorge A.G., de Sousa S.M., Boschero A.C., Saad M.J., Velloso L.A., and Rocha E.M. Insulin secretion by rat lacrimal glands: effects of systemic and local variables. Am. J. Physiol.: Endocrinol. Metab. 289 (2005) E768-E775
16. Alves M., Cunha D.A., Calegari V.C., Saad M.J., Boschero A.C., Velloso L.A., and Rocha E.M. Nuclear factor-kappaB and advanced glycation end-products expression in lacrimal glands of aging rats. J. Endocrinol. 187 (2005) 159-166
17. Leite S.C., de Castro R.S., Alves M., Cunha D.A., Correa M.E., da Silveira L.A., Vigorito A.C., de Souza C.A., and Rocha E.M. Risk factors and characteristics of ocular complications, and efficacy of autologous serum tears after haematopoietic progenitor cell transplantation. Bone Marrow Transplant. 38 (2006) 223-227
18. Hann L.E., Kelleher R.S., and Sullivan D.A. Influence of culture conditions on the androgen control of secretory component production by acinar cells from the rat lacrimal gland. Invest. Ophthalmol. Visual Sci. 32 (1991) 2610-2621
19. Lindberg K., Brown M.E., Chaves H.V., Kenyon K.R., and Rheinwald J.G. In vitro propagation of human ocular surface epithelial cells for transplantation. Invest. Ophthalmol. Visual Sci. 34 (1993) 2672-2679
20. Alves M., Calegari V.C., Cunha D.A., Saad M.J., Velloso L.A., and Rocha E.M. Increased expression of advanced glycation end-products and their receptor, and activation of nuclear factor kappa-B in lacrimal glands of diabetic rats. Diabetologia 48 (2005) 2675-2681
21. Rocha E.M., de M.L.M.H., Carvalho C.R., Saad M.J., and Velloso L.A. Characterization of the insulin-signaling pathway in lacrimal and salivary glands of rats. Curr. Eye Res. 21 (2000) 833-842
22. Rocha E.M., Carvalho C.R., Saad M.J., and Velloso L.A. The influence of ageing on the insulin signalling system in rat lacrimal and salivary glands. Acta Ophthalmol. Scand. 81 (2003) 639-645
23. Rocha E.M., Hirata A.E., Carneiro E.M., Saad M.J., and Velloso L.A. Impact of gender on insulin signaling pathway in lacrimal and salivary glands of rats. Endocrine 18 (2002) 191-199
24. Zoukhri D., and Kublin C.L. Impaired neurotransmitter release from lacrimal and salivary gland nerves of a murine model of Sjogren's syndrome. Invest. Ophthalmol Visual Sci. 42 (2001) 925-932
25. Bromberg B.B., and Welch M.H. Lacrimal protein secretion: comparison of young and old rats. Exp. Eye Res. 40 (1985) 313-320
26. Oberley L.W. Free radicals and diabetes. Free Radic. Biol. Med. 5 (1988) 113-124
27. Lenzen S., Drinkgern J., and Tiedge M. Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues. Free Radic. Biol. Med. 20 (1996) 463-466
28. Esterbauer H., and Cheeseman K.H. Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods Enzymol. 186 (1990) 407-421
29. Boschero A.C., Szpak-Glasman M., Carneiro E.M., Bordin S., Paul I., Rojas E., and Atwater I. Oxotremorine-m potentiation of glucose-induced insulin release from rat islets involves M3 muscarinic receptors. Am. J. Physiol. 268 (1995) E336-E342
30. Stoppiglia L.F., Nogueira T.A., Leite A.R., Carneiro E.M., and Boschero A.C. Protective effect of d-glucose, l-leucine and fetal calf serum against oxidative stress in neonatal pancreatic islets. Biochim. Biophys. Acta 1588 (2002) 113-118
31. Goto Y., Kida K., Kaino Y., Ito T., and Matsuda H. An extrapancreatic action of diazoxide to inhibit glucose transport activity on adipocytes. Acta Paediatr. Jpn. 36 (1994) 128-132
32. Bromberg B.B. Autonomic control of lacrimal protein secretion. Invest. Ophthalmol Visual Sci. 20 (1981) 110-116
33. Rios J.D., Horikawa Y., Chen L.L., Kublin C.L., Hodges R.R., Dartt D.A., and Zoukhri D. Age-dependent alterations in mouse exorbital lacrimal gland structure, innervation and secretory response. Exp. Eye Res. 80 (2005) 477-491
34. Paliwal A., and De P.K. Marked sexual dimorphism of lacrimal gland peroxidase in hamster: repression by androgens and estrogens. Biochem. Biophys. Res. Commun. 341 (2006) 1286-1293
35. Nogueira F.N., Carvalho A.M., Yamaguti P.M., and Nicolau J. Antioxidant parameters and lipid peroxidation in salivary glands of streptozotocin-induced diabetic rats. Clin. Chim. Acta 353 (2005) 133-139
36. Terashima T., Kojima H., Fujimiya M., Matsumura K., Oi J., Hara M., Kashiwagi A., Kimura H., Yasuda H., and Chan L. The fusion of bone-marrow-derived proinsulin-expressing cells with nerve cells underlies diabetic neuropathy. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 12525-12530
37. Kojima H., Fujimiya M., Terashima T., Kimura H., and Chan L. Extrapancreatic proinsulin/insulin-expressing cells in diabetes mellitus: is history repeating itself?. Endocr. J. 53 (2006) 715-722
38. Friesen N.T., Buchau A.S., Schott-Ohly P., Lgssiar A., and Gleichmann H. Generation of hydrogen peroxide and failure of antioxidative responses in pancreatic islets of male C57BL/6 mice are associated with diabetes induced by multiple low doses of streptozotocin. Diabetologia 47 (2004) 676-685
39. Saragas S., Arffa R., Rabin B., Kronish J., Miller D., and Mayman C. Reversal of wound strength retardation by addition of insulin to corticosteroid therapy. Ann. Ophthalmol. 17 (1985) 428-430