-
1
-
-
2942746713
-
Biotransformation of methyl parathion by glutathione S-transferases
-
Abel, EL, Bammler, TK and Eaton, DL (2004) Biotransformation of methyl parathion by glutathione S-transferases. Toxicological Sciences, 79, pp. 224-232.
-
(2004)
Toxicological Sciences
, vol.79
, pp. 224-232
-
-
Abel, E.L.1
Bammler, T.K.2
Eaton, D.L.3
-
2
-
-
0030899372
-
Molecular cloning, characterisation, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. Evidence for differential catalyic activity of the encoded proteins
-
Ali-Osman, F., Akande, O., Antoun, G., Mao, JX and Buolamwini, J. (1997) Molecular cloning, characterisation, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. Evidence for differential catalyic activity of the encoded proteins. Journal of Biological Chemistry, 272, pp. 10004-10012.
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 10004-10012
-
-
Ali-Osman, F.1
Akande, O.2
Antoun, G.3
Mao, J.X.4
Buolamwini, J.5
-
3
-
-
0036124107
-
CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
-
Bradford, LD (2002) CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics, 3, pp. 229-243.
-
(2002)
Pharmacogenomics
, vol.3
, pp. 229-243
-
-
Bradford, L.D.1
-
4
-
-
0034744258
-
Health and exposures of United Kingdom Gulf War Veterans. Part I: The pattern and extent of ill health
-
Cherry, N., Creed, F., Silman, A., Dunn, G., Baxter, D., Smedley, J., Taylor, S. and Macfarlane, GJ (2001) Health and exposures of United Kingdom Gulf War Veterans. Part I: The pattern and extent of ill health. Occupational and Environmental Medicine, 58, pp. 291-298.
-
(2001)
Occupational and Environmental Medicine
, vol.58
, pp. 291-298
-
-
Cherry, N.1
Creed, F.2
Silman, A.3
Dunn, G.4
Baxter, D.5
Smedley, J.6
Taylor, S.7
Macfarlane, G.J.8
-
5
-
-
0037006652
-
Paraoxonase (PON1) polymorphisms in farmers attributing ill-health to sheep dip
-
Cherry, NM, Mackness, M., Durrington, P., Povey, AC, Dippnall, WM, Smith, AE and Mackness, B. (2002) Paraoxonase (PON1) polymorphisms in farmers attributing ill-health to sheep dip. Lancet, 359, pp. 763-764.
-
(2002)
Lancet
, vol.359
, pp. 763-764
-
-
Cherry, N.M.1
Mackness, M.2
Durrington, P.3
Povey, A.C.4
Dippnall, W.M.5
Smith, A.E.6
Mackness, B.7
-
6
-
-
34547475261
-
-
Department of Health
-
(1999) Department of Health
-
(1999)
-
-
-
7
-
-
0037639963
-
Functional genomic of the paraoxonase (PON1) polymorphisms: Effects on pesticide sensitivity, cardiovascular disease, and drug metabolism
-
Costa, LG, Cole, TB, Jarvik, GP and Furlong, CE (2003) Functional genomic of the paraoxonase (PON1) polymorphisms: Effects on pesticide sensitivity, cardiovascular disease, and drug metabolism. Annual Review of Medicine, 54, pp. 371-392.
-
(2003)
Annual Review of Medicine
, vol.54
, pp. 371-392
-
-
Costa, L.G.1
Cole, T.B.2
Jarvik, G.P.3
Furlong, C.E.4
-
8
-
-
0030293198
-
The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin
-
Davies, HG, Richter, RJ, Keifer, M., Broomfield, CA, Sowalla, J. and Furlong, CE (1996) The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin. Nature Genetics, 14, pp. 334-336.
-
(1996)
Nature Genetics
, vol.14
, pp. 334-336
-
-
Davies, H.G.1
Richter, R.J.2
Keifer, M.3
Broomfield, C.A.4
Sowalla, J.5
Furlong, C.E.6
-
10
-
-
0036746062
-
-
Donn, R., Alourfi, Z., De Benedetti, F., Meazza, C., Zeggini, E., Lunt, M., Stevens, A., Shelley, E., Lamb, R., Ollier, WER, Thompson, W. and Ray, D. (2002) Mutation screening of the macrophage migration inhibitory factor gene: Positive association of a functional polymorphism of macrophage migration inhibitory factor with juvenile idiopathic arthritis. 46, pp. 2402-2409.
-
(2002)
Mutation Screening of the Macrophage Migration Inhibitory Factor Gene: Positive Association of a Functional Polymorphism of Macrophage Migration Inhibitory Factor With Juvenile Idiopathic Arthritis
, vol.46
, pp. 2402-2409
-
-
Donn, R.1
Alourfi, Z.2
De Benedetti, F.3
Meazza, C.4
Zeggini, E.5
Lunt, M.6
Stevens, A.7
Shelley, E.8
Lamb, R.9
Ollier, W.E.R.10
Thompson, W.11
Ray, D.12
-
11
-
-
0034104195
-
Biotransformation enzyme polymorphism and pesticide susceptibility
-
Eaton, DL (2000) Biotransformation enzyme polymorphism and pesticide susceptibility. Neurotoxicology, 21, pp. 101-112.
-
(2000)
Neurotoxicology
, vol.21
, pp. 101-112
-
-
Eaton, D.L.1
-
12
-
-
0032607623
-
Identification of the cytochrome p450 isoenzymes involved in the metabolism of diazinon in the rat liver
-
Fabrizi, L., Gemma, S., Testai, E. and Vittozzi, L. (1999) Identification of the cytochrome p450 isoenzymes involved in the metabolism of diazinon in the rat liver. Journal of Biochemical and Molecular Toxicology, 13, pp. 53-61.
-
(1999)
Journal of Biochemical and Molecular Toxicology
, vol.13
, pp. 53-61
-
-
Fabrizi, L.1
Gemma, S.2
Testai, E.3
Vittozzi, L.4
-
13
-
-
0034051557
-
Genetic and temporal determinants of pesticide sensitivity: Role of paraoxonase (PON1)
-
Furlong, CE, Li, WF, Richter, RJ, Shih, DM, Lusis, AJ, Alleva, E. and Costa, LG (2000) Genetic and temporal determinants of pesticide sensitivity: Role of paraoxonase (PON1). Neurotoxicology, 21, pp. 91-100.
-
(2000)
Neurotoxicology
, vol.21
, pp. 91-100
-
-
Furlong, C.E.1
Li, W.F.2
Richter, R.J.3
Shih, D.M.4
Lusis, A.J.5
Alleva, E.6
Costa, L.G.7
-
14
-
-
0002198623
-
Paraoxonase polymorphism Met-Leu 54 is associated with modified serum concentrations of the enzyme. A possible link between the paraoxonase gene and increased risk of cardiovascular disease in diabetes
-
Garin, MC, James, RW, Dussoix, P., Blanche, M., Passa, P., Froguel, P. and Ruiz, J. (1997) Paraoxonase polymorphism Met-Leu 54 is associated with modified serum concentrations of the enzyme. A possible link between the paraoxonase gene and increased risk of cardiovascular disease in diabetes. Journal of Clinical Investigation, 99, pp. 62-66.
-
(1997)
Journal of Clinical Investigation
, vol.99
, pp. 62-66
-
-
Garin, M.C.1
James, R.W.2
Dussoix, P.3
Blanche, M.4
Passa, P.5
Froguel, P.6
Ruiz, J.7
-
15
-
-
0032054961
-
Association between glutathione S-transferase M1, P1, and T1 genetic polymorphisms and development of breast cancer
-
Helzlsouer, KJ, Selmin, O., Huang, HY, Strickland, PT, Hoffman, S., Alberg, AJ, Watson, M., Comstock, GW and Bell, D. (1998) Association between glutathione S-transferase M1, P1, and T1 genetic polymorphisms and development of breast cancer. Journal of the National Cancer Institute, 90, pp. 512-518.
-
(1998)
Journal of the National Cancer Institute
, vol.90
, pp. 512-518
-
-
Helzlsouer, K.J.1
Selmin, O.2
Huang, H.Y.3
Strickland, P.T.4
Hoffman, S.5
Alberg, A.J.6
Watson, M.7
Comstock, G.W.8
Bell, D.9
-
16
-
-
10744232131
-
Paraoxonase activity and genetic polymorphisms in greenhouse workers with long-term pesticide exposure
-
Hernandez, AF, Mackness, B., Rodrigo, L., Lopez, O., Pla, A., Gil, F., Durrington, PN, Pena, G., Perron, T., Serrano, JL and Mackness, MI (2003) Paraoxonase activity and genetic polymorphisms in greenhouse workers with long-term pesticide exposure. Human and Experimental Toxicology, 22, pp. 505-574.
-
(2003)
Human and Experimental Toxicology
, vol.22
, pp. 505-574
-
-
Hernandez, A.F.1
Mackness, B.2
Rodrigo, L.3
Lopez, O.4
Pla, A.5
Gil, F.6
Durrington, P.N.7
Pena, G.8
Perron, T.9
Serrano, J.L.10
Mackness, M.I.11
-
17
-
-
0027396833
-
The molecular basis for the human serum paraoxonase activity polymorphism
-
Humbert, R., Adler, DA, Disteche, CM, Hassett, C., Omiecinski, CJ and Furlong, CE (1993) The molecular basis for the human serum paraoxonase activity polymorphism. Nature Genetics, 3, pp. 73-76.
-
(1993)
Nature Genetics
, vol.3
, pp. 73-76
-
-
Humbert, R.1
Adler, D.A.2
Disteche, C.M.3
Hassett, C.4
Omiecinski, C.J.5
Furlong, C.E.6
-
18
-
-
13544249943
-
Genetic polymorphisms of cytochrome p450 2D6 (CYP2D6): Clinical consequences, evolutionary aspects and functional diversity
-
Ingelman-Sundberg, M. (2005) Genetic polymorphisms of cytochrome p450 2D6 (CYP2D6): Clinical consequences, evolutionary aspects and functional diversity. Pharmacogenomics Journal, 5, pp. 6-13.
-
(2005)
Pharmacogenomics Journal
, vol.5
, pp. 6-13
-
-
Ingelman-Sundberg, M.1
-
19
-
-
0035949809
-
Biotransformation of organophosphorus compounds
-
Jokanovic, M. (2001) Biotransformation of organophosphorus compounds. Toxicology, 166, pp. 139-160.
-
(2001)
Toxicology
, vol.166
, pp. 139-160
-
-
Jokanovic, M.1
-
20
-
-
0035891564
-
Diazinon is activated by CYP2C19 in human liver
-
Kappers, WA, Edwards, RJ, Murray, S. and Boobis, AR (2001) Diazinon is activated by CYP2C19 in human liver. Toxicology and Applied Pharmacology, 177, pp. 68-76.
-
(2001)
Toxicology and Applied Pharmacology
, vol.177
, pp. 68-76
-
-
Kappers, W.A.1
Edwards, R.J.2
Murray, S.3
Boobis, A.R.4
-
21
-
-
0035071598
-
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
-
Kuehl, P., Zhang, J., Lin, Y., Lamba, J., Assem, M., Schuetz, J., Watkins, PB, Daly, A., Wrighton, SA, Hall, SD, Maurel, P., Relling, M., Brimer, C., Yasuda, K., Venkataramanan, R., Strom, S., Thummel, K., Boguski, MS and Schuetz, E. (2001) Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nature Genetics, 27, pp. 383-391.
-
(2001)
Nature Genetics
, vol.27
, pp. 383-391
-
-
Kuehl, P.1
Zhang, J.2
Lin, Y.3
Lamba, J.4
Assem, M.5
Schuetz, J.6
Watkins, P.B.7
Daly, A.8
Wrighton, S.A.9
Hall, S.D.10
Maurel, P.11
Relling, M.12
Brimer, C.13
Yasuda, K.14
Venkataramanan, R.15
Strom, S.16
Thummel, K.17
Boguski, M.S.18
Schuetz, E.19
-
22
-
-
0035056687
-
Serum paraoxonase (PON1) isozymes: The quantitative analysis of isozymes effecting individual sensitivity to environmental chemicals
-
La Du, BN, Billecke, S., Hsu, C., Haley, RW and Broomfield, CA (2001) Serum paraoxonase (PON1) isozymes: The quantitative analysis of isozymes effecting individual sensitivity to environmental chemicals. Drug Metabolism and Disposition, 29, pp. 566-569.
-
(2001)
Drug Metabolism and Disposition
, vol.29
, pp. 566-569
-
-
La Du, B.N.1
Billecke, S.2
Hsu, C.3
Haley, R.W.4
Broomfield, C.A.5
-
23
-
-
0037131879
-
Genetic contribution to variable human CYP3A-mediated metabolism
-
Lamba, JK, Lin, YS, Schuetz, EG and Thumme, KE (2002) Genetic contribution to variable human CYP3A-mediated metabolism. Advances in Drug Delivery Reviews, 54, pp. 1271-1290.
-
(2002)
Advances in Drug Delivery Reviews
, vol.54
, pp. 1271-1290
-
-
Lamba, J.K.1
Lin, Y.S.2
Schuetz, E.G.3
Thumme, K.E.4
-
24
-
-
0345505719
-
Association between human paraoxonase gene polymorphisms and chronic symptoms in pesticide-exposed workers
-
Lee, BW, London, L., Paulauskis, J., Myers, J. and Christiani, DC (2003) Association between human paraoxonase gene polymorphisms and chronic symptoms in pesticide-exposed workers. Journal of Occupational and Environmental Medicine, 45, pp. 118-122.
-
(2003)
Journal of Occupational and Environmental Medicine
, vol.45
, pp. 118-122
-
-
Lee, B.W.1
London, L.2
Paulauskis, J.3
Myers, J.4
Christiani, D.C.5
-
25
-
-
0037189032
-
GSTM1, GSTT1 and GSTP1 polymorphisms and lung cancer risk
-
Lewis, SJ, Cherry, NM, McLNiven, R., Barber, PV and Povey, AC (2002) GSTM1, GSTT1 and GSTP1 polymorphisms and lung cancer risk. Cancer Letters, 180, pp. 165-171.
-
(2002)
Cancer Letters
, vol.180
, pp. 165-171
-
-
Lewis, S.J.1
Cherry, N.M.2
McLNiven, R.3
Barber, P.V.4
Povey, A.C.5
-
26
-
-
0034524737
-
Catalytic efficiency determines the in vivo efficacy of PON1 for detoxifying organophosphorous compounds
-
Li, W-F, Costa, LG, Richter, RJ, Hagen, T., Shih, DM, Tward, A., Lusis, AJ and Furlong, CE (2000) Catalytic efficiency determines the in vivo efficacy of PON1 for detoxifying organophosphorous compounds. Pharmacogenetics, 10, pp. 767-779.
-
(2000)
Pharmacogenetics
, vol.10
, pp. 767-779
-
-
Li, W.-F.1
Costa, L.G.2
Richter, R.J.3
Hagen, T.4
Shih, D.M.5
Tward, A.6
Lusis, A.J.7
Furlong, C.E.8
-
27
-
-
0032168831
-
Human serum paraoxonase
-
Mackness, B., Durrington, PN and Mackness, MI (1998) Human serum paraoxonase. General Pharmacology, 31, pp. 329-336.
-
(1998)
General Pharmacology
, vol.31
, pp. 329-336
-
-
Mackness, B.1
Durrington, P.N.2
Mackness, M.I.3
-
28
-
-
0032512704
-
Effect of the human serum paraoxonase 55 and 192 genetic polymorphisms on the protection by high density lipoprotein against low density lipoprotein oxidative modifications
-
Mackness, B., Mackness, MI, Arrol, T., Turkie, W. and Durrington, PN (1998) Effect of the human serum paraoxonase 55 and 192 genetic polymorphisms on the protection by high density lipoprotein against low density lipoprotein oxidative modifications. FEBS Letters, 423, pp. 57-60.
-
(1998)
FEBS Letters
, vol.423
, pp. 57-60
-
-
Mackness, B.1
Mackness, M.I.2
Arrol, T.3
Turkie, W.4
Durrington, P.N.5
-
29
-
-
0037325527
-
Paraoxonase and susceptibility to organophosphorus poisoning in farmers dipping sheep
-
Mackness, B., Durrington, P., Povey, AC, Thomson, S., Middleton, S., Dippnall, M., Mackness, M., Smith, AR and Cherry, NM (2003) Paraoxonase and susceptibility to organophosphorus poisoning in farmers dipping sheep. Pharmacogenetics, 13, pp. 81-88.
-
(2003)
Pharmacogenetics
, vol.13
, pp. 81-88
-
-
Mackness, B.1
Durrington, P.2
Povey, A.C.3
Thomson, S.4
Middleton, S.5
Dippnall, M.6
Mackness, M.7
Smith, A.R.8
Cherry, N.M.9
-
30
-
-
0028237981
-
Frequency distribution of dapsone N-hydroxylase, a putative probe for p4503A4 activity in a white population
-
May, DG, Porter, J., Wilkinson, GR and Branch, RA (1994) Frequency distribution of dapsone N-hydroxylase, a putative probe for p4503A4 activity in a white population. Clinical Pharmacology and Therapeutics, 55, pp. 492-500.
-
(1994)
Clinical Pharmacology and Therapeutics
, vol.55
, pp. 492-500
-
-
May, D.G.1
Porter, J.2
Wilkinson, G.R.3
Branch, R.A.4
-
31
-
-
0032564134
-
Parkinson's disease, pesticides and glutathione transferase polymorphisms
-
Menegon, A., Board, PG, Blackburn, AC, Mellick, GD and Couteur, DG Le (1998) Parkinson's disease, pesticides and glutathione transferase polymorphisms. Lancet, 352, pp. 1344-1346.
-
(1998)
Lancet
, vol.352
, pp. 1344-1346
-
-
Menegon, A.1
Board, P.G.2
Blackburn, A.C.3
Mellick, G.D.4
Couteur Le, D.G.5
-
32
-
-
0042357440
-
PM frequencies of major CYPs in Asians and Caucasians
-
Mizutani, T. (2003) PM frequencies of major CYPs in Asians and Caucasians. Drug Metabolism Reviews, 35, pp. 99-106.
-
(2003)
Drug Metabolism Reviews
, vol.35
, pp. 99-106
-
-
Mizutani, T.1
-
33
-
-
0002431731
-
Glutathione S-transferases: Their role in the metabolism of organophosphorous insecticides
-
Motoyama, N. and Dauterman, WC (1980) Glutathione S-transferases: Their role in the metabolism of organophosphorous insecticides. Reviews in Biochemical Toxicology, 2, pp. 49-69.
-
(1980)
Reviews in Biochemical Toxicology
, vol.2
, pp. 49-69
-
-
Motoyama, N.1
Dauterman, W.C.2
-
34
-
-
0033067399
-
The role of metabolism in determining susceptibility to parathion toxicity in man
-
Mutch, E., Blain, PG and Williams, FM (1999) The role of metabolism in determining susceptibility to parathion toxicity in man. Toxicology Letters, 107, pp. 177-187.
-
(1999)
Toxicology Letters
, vol.107
, pp. 177-187
-
-
Mutch, E.1
Blain, P.G.2
Williams, F.M.3
-
35
-
-
0035934446
-
Host determinants of DNA alkylation and DNA repair activity in human colorectal tissue: O 6-methylguanine levels are associated with GST-T1 genotype and O 6-alkylguanine-DNA alkyltransferase activity with CYP2D6 genotype
-
Povey, AC, Guppy, MJ, Hall, CN, Jackson, PE, Badawi, AF, Cooper, DP, O'Connor, PJ and Margison, GP (2001) Host determinants of DNA alkylation and DNA repair activity in human colorectal tissue: O 6-methylguanine levels are associated with GST-T1 genotype and O 6-alkylguanine-DNA alkyltransferase activity with CYP2D6 genotype. Mutation Research, 495, pp. 103-115.
-
(2001)
Mutation Research
, vol.495
, pp. 103-115
-
-
Povey, A.C.1
Guppy, M.J.2
Hall, C.N.3
Jackson, P.E.4
Badawi, A.F.5
Cooper, D.P.6
O'Connor, P.J.7
Margison, G.P.8
-
36
-
-
26844563311
-
Paraoxonase polymorphisms and self-reported chronic ill-health in farmers dipping sheep
-
Povey, AC, Mackness, MI, Durrington, PN, Dippnall, M., Smith, AE, Mackness, B. and Cherry, NM (2005) Paraoxonase polymorphisms and self-reported chronic ill-health in farmers dipping sheep. Occupational Medicine, 55, pp. 282-286.
-
(2005)
Occupational Medicine
, vol.55
, pp. 282-286
-
-
Povey, A.C.1
Mackness, M.I.2
Durrington, P.N.3
Dippnall, M.4
Smith, A.E.5
Mackness, B.6
Cherry, N.M.7
-
37
-
-
0030858074
-
Molecular epidemiology of the human glutathione s-transferase genotypes GSTM1 and GSTT1 in cancer susceptibility
-
Rebbeck, TR (1997) Molecular epidemiology of the human glutathione s-transferase genotypes GSTM1 and GSTT1 in cancer susceptibility. Cancer Epidemiology Biomarkers Prevention, 6, pp. 733-743.
-
(1997)
Cancer Epidemiology Biomarkers Prevention
, vol.6
, pp. 733-743
-
-
Rebbeck, T.R.1
-
38
-
-
0032547341
-
Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4
-
Rebbeck, TR, Jaffe, JM, Walker, AH, Wein, AJ and Malkowicz, SB (1998) Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4. Journal of the National Cancer Institute, 90, pp. 1225-1229.
-
(1998)
Journal of the National Cancer Institute
, vol.90
, pp. 1225-1229
-
-
Rebbeck, T.R.1
Jaffe, J.M.2
Walker, A.H.3
Wein, A.J.4
Malkowicz, S.B.5
-
39
-
-
0004194682
-
Organophosphate sheep dip: Clinical aspects of long term low-dose exposure
-
Royal College of Physicians of London and the Royal College of Psychiatrists, Royal College of Physicians of London and the Royal College of Psychiatrists, London
-
(1998) Organophosphate sheep dip: Clinical aspects of long term low-dose exposure. Royal College of Physicians of London and the Royal College of Psychiatrists, Royal College of Physicians of London and the Royal College of Psychiatrists, London
-
(1998)
-
-
-
40
-
-
0031038038
-
Cytochrome P450 2D6 variants in a Caucasian population: Allele frequencies and phenotypic consequences
-
Sachse, C., Brockmoller, J., Bauer, S. and Roots, I. (1997) Cytochrome P450 2D6 variants in a Caucasian population: Allele frequencies and phenotypic consequences. American Journal of Human Genetics, 60, pp. 284-289.
-
(1997)
American Journal of Human Genetics
, vol.60
, pp. 284-289
-
-
Sachse, C.1
Brockmoller, J.2
Bauer, S.3
Roots, I.4
-
41
-
-
0034674894
-
Evidence for the activation of organophosphate pesticides by cytochromes p450 3A4 and 2D6 in human liver microsomes
-
Sams, C., Mason, HJ and Rawbone, R. (2000) Evidence for the activation of organophosphate pesticides by cytochromes p450 3A4 and 2D6 in human liver microsomes. Toxicology Letters, 116, pp. 217-221.
-
(2000)
Toxicology Letters
, vol.116
, pp. 217-221
-
-
Sams, C.1
Mason, H.J.2
Rawbone, R.3
-
42
-
-
10644293868
-
Biotransformation of chlorpyrifos and diazinon by human liver microsomes and recombinant human cytochrome p450s (CYP)
-
Sams, C., Cocker, J. and Lennard, MS (2004) Biotransformation of chlorpyrifos and diazinon by human liver microsomes and recombinant human cytochrome p450s (CYP). Xenobiotica, 34, pp. 861-873.
-
(2004)
Xenobiotica
, vol.34
, pp. 861-873
-
-
Sams, C.1
Cocker, J.2
Lennard, M.S.3
-
43
-
-
0033632228
-
CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: Evidence for an allelic variant with altered catalytic activity
-
Sata, F., Sapone, A., Elizondo, G., Stocker, P., Miller, VP, Zheng, W., Raunio, H., Crespi, CL and Gonzalez, FJ (2000) CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: Evidence for an allelic variant with altered catalytic activity. Clinical Pharmacology and Therapeutics, 67, pp. 48-56.
-
(2000)
Clinical Pharmacology and Therapeutics
, vol.67
, pp. 48-56
-
-
Sata, F.1
Sapone, A.2
Elizondo, G.3
Stocker, P.4
Miller, V.P.5
Zheng, W.6
Raunio, H.7
Crespi, C.L.8
Gonzalez, F.J.9
-
44
-
-
0032537833
-
Mice lacking serum paroxonase are susceptible to organophosphate toxicity and atherosclerosis
-
Shih, DM, Xia, Y-R, Navab, M., Li, W-F, Hama, S., Castellani, LW, Furlong, CE, Costa, LG, Fogelman, AM and Lusis, AJ (1998) Mice lacking serum paroxonase are susceptible to organophosphate toxicity and atherosclerosis. Nature, 394, pp. 284-287.
-
(1998)
Nature
, vol.394
, pp. 284-287
-
-
Shih, D.M.1
Xia, Y.-R.2
Navab, M.3
Li, W.-F.4
Hama, S.5
Castellani, L.W.6
Furlong, C.E.7
Costa, L.G.8
Fogelman, A.M.9
Lusis, A.J.10
-
45
-
-
0026747176
-
Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease
-
Smith, CAD, Gough, AC, Leigh, PN, Summers, BA, Harding, AE, Maranganore, DM, Sturman, SG, Schapira, AHV, Williams, AC, Spurr, NK and Wolf, CR (1992) Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease. Lancet, 339, pp. 1375-1377.
-
(1992)
Lancet
, vol.339
, pp. 1375-1377
-
-
Smith, C.A.D.1
Gough, A.C.2
Leigh, P.N.3
Summers, B.A.4
Harding, A.E.5
Maranganore, D.M.6
Sturman, S.G.7
Schapira, A.H.V.8
Williams, A.C.9
Spurr, N.K.10
Wolf, C.R.11
-
46
-
-
0035479754
-
Glutathione-S-transferase family of enzymes
-
Strange, RC, Spiteri, MA, Ramachandran, S. and Fryer, AA (2001) Glutathione-S-transferase family of enzymes. Mutation Research, 482, pp. 21-26.
-
(2001)
Mutation Research
, vol.482
, pp. 21-26
-
-
Strange, R.C.1
Spiteri, M.A.2
Ramachandran, S.3
Fryer, A.A.4
-
47
-
-
0002277675
-
Role of glutathione in the mammalian detoxication of organophosphorus insecticides
-
Academic Press, San Diego
-
Sultatos, LG (1992) Role of glutathione in the mammalian detoxication of organophosphorus insecticides. Organophosphates: Chemistry, fate and effects, pp. 155-168. Academic Press, San Diego
-
(1992)
Organophosphates: Chemistry, Fate and Effects
, pp. 155-168
-
-
Sultatos, L.G.1
-
48
-
-
0029947171
-
Human glutathione S-transferase T1-1 enhances mutagenicity of 1,2-dibromoethane, dibromomethane and 1,2,3,4-diepoxybutane in Salmonella typhimurium
-
Thier, R., Pemble, SE, Kramer, H., Taylor, JB, Guengerich, FP and Ketterer, B. (1996) Human glutathione S-transferase T1-1 enhances mutagenicity of 1,2-dibromoethane, dibromomethane and 1,2,3,4-diepoxybutane in Salmonella typhimurium. Carcinogenesis, 17, pp. 163-166.
-
(1996)
Carcinogenesis
, vol.17
, pp. 163-166
-
-
Thier, R.1
Pemble, S.E.2
Kramer, H.3
Taylor, J.B.4
Guengerich, F.P.5
Ketterer, B.6
-
49
-
-
0345643389
-
Interindividual differences in hepatic expression of CYP3A4: Relationship to genetic polymorphism in the 5'-upstream regulatory region
-
Westlind, A., Lofberg, L., Tindber, N., Andersson, TB and Ingelman-Sundberg, M. (1999) Interindividual differences in hepatic expression of CYP3A4: Relationship to genetic polymorphism in the 5'-upstream regulatory region. Biochemical and Biophysical Research Communications, 259, pp. 201-205.
-
(1999)
Biochemical and Biophysical Research Communications
, vol.259
, pp. 201-205
-
-
Westlind, A.1
Lofberg, L.2
Tindber, N.3
Andersson, T.B.4
Ingelman-Sundberg, M.5
-
51
-
-
0742286803
-
Cytochrome p450 2D6: Overview and update on pharmacology, genetics, biochemistry
-
Zanger, UM, Raimundo, S. and Eichelbaum, M. (2004) Cytochrome p450 2D6: overview and update on pharmacology, genetics, biochemistry. Naunyn-Schmiedeberg's Archives of Pharmacology, 369, pp. 23-37.
-
(2004)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.369
, pp. 23-37
-
-
Zanger, U.M.1
Raimundo, S.2
Eichelbaum, M.3
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