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Volumn 21, Issue 7, 2007, Pages 1413-1422

Role of MTHFR (677, 1298) haplotype in the risk of developing secondary leukemia after treatment of breast cancer and hematological malignancies

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ALANINE; ANTINEOPLASTIC AGENT; CARMUSTINE; CELL PROTEIN; CHLORAMBUCIL; CISPLATIN; CYCLOPHOSPHAMIDE; CYSTEINE; CYTARABINE; DAUNORUBICIN; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; FLUDARABINE; FLUOROURACIL; GLUTATHIONE TRANSFERASE; IDARUBICIN; IFOSFAMIDE; MELPHALAN; METHOTREXATE; MITOXANTRONE; NIBRIN; PREDNIMUSTINE; THREONINE; VINBLASTINE; VINCRISTINE; XERODERMA PIGMENTOSUM GROUP C PROTEIN;

EID: 34250892460     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2404709     Document Type: Article
Times cited : (46)

References (42)
  • 1
    • 0038305924 scopus 로고    scopus 로고
    • Clinical-cytogenetic associations in 306 patients with therapy-related myelodysplasia and myeloid leukemia: The University of Chicago series
    • Smith SM, Le Beau MM, Huo D, Karrison T, Sobecks RM, Anastasi J et al. Clinical-cytogenetic associations in 306 patients with therapy-related myelodysplasia and myeloid leukemia: The University of Chicago series. Blood 2003; 102: 43-52.
    • (2003) Blood , vol.102 , pp. 43-52
    • Smith, S.M.1    Le Beau, M.M.2    Huo, D.3    Karrison, T.4    Sobecks, R.M.5    Anastasi, J.6
  • 2
    • 33750326207 scopus 로고    scopus 로고
    • Alternative genetic pathways and cooperating genetic abnormalities in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia
    • Pedersen-Bjergaard J, Christiansen DH, Desta F, Andersen MK. Alternative genetic pathways and cooperating genetic abnormalities in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia. Leukemia 2006; 20: 1943-1949.
    • (2006) Leukemia , vol.20 , pp. 1943-1949
    • Pedersen-Bjergaard, J.1    Christiansen, D.H.2    Desta, F.3    Andersen, M.K.4
  • 3
    • 3242875428 scopus 로고    scopus 로고
    • Therapy-related leukemia and myelodysplasia: Evolving concepts of pathogenesis and treatment
    • Rund D, Ben-Yehuda D. Therapy-related leukemia and myelodysplasia: evolving concepts of pathogenesis and treatment. Hematology 2004; 9: 179-187.
    • (2004) Hematology , vol.9 , pp. 179-187
    • Rund, D.1    Ben-Yehuda, D.2
  • 4
    • 0342680138 scopus 로고    scopus 로고
    • Therapy related acute myeloid leukemia after exposure to 5-fluorouracil: A case report
    • Turker A, Guler N. Therapy related acute myeloid leukemia after exposure to 5-fluorouracil: A case report. Hematol Cell Ther 1999; 41 195-196.
    • (1999) Hematol Cell Ther , vol.41 , pp. 195-196
    • Turker, A.1    Guler, N.2
  • 5
    • 0035055918 scopus 로고    scopus 로고
    • Genetic predisposition and treatment-related leukemia
    • Perentesis JP. Genetic predisposition and treatment-related leukemia. Med Pediatr Oncol 2001; 36: 541-548.
    • (2001) Med Pediatr Oncol , vol.36 , pp. 541-548
    • Perentesis, J.P.1
  • 6
    • 0037111669 scopus 로고    scopus 로고
    • The genotype distribution of the XRCC1 gene indicates a role for base excision repair in the development of therapy-related acute myeloblastic leukemia
    • Seedhouse C, Bainton R, Lewis M, Harding A, Russell N, Das-Gupta E. The genotype distribution of the XRCC1 gene indicates a role for base excision repair in the development of therapy-related acute myeloblastic leukemia. Blood 2002; 100: 3761-3766.
    • (2002) Blood , vol.100 , pp. 3761-3766
    • Seedhouse, C.1    Bainton, R.2    Lewis, M.3    Harding, A.4    Russell, N.5    Das-Gupta, E.6
  • 7
    • 0035949708 scopus 로고    scopus 로고
    • Polymorphism in glutathione S-transferase P1 is associated with susceptibility to chemotherapy-induced leukemia
    • Allan JM, Wild CP, Rollinson S, Willett EV, Moorman AV, Dovey GJ et al. Polymorphism in glutathione S-transferase P1 is associated with susceptibility to chemotherapy-induced leukemia. Proc Natl Acad Sci USA 2001; 98: 11592-11597.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 11592-11597
    • Allan, J.M.1    Wild, C.P.2    Rollinson, S.3    Willett, E.V.4    Moorman, A.V.5    Dovey, G.J.6
  • 8
    • 0033564977 scopus 로고    scopus 로고
    • Prevalence of the inactivating 609C → T polymorphism in the NAD(P)H:qUinone oxidoreductase (NQO1) gene in patients with primary and therapy-related myeloid leukemia
    • Larson RA, Wang Y, Banerjee M, Wiemels J, Hartford C, Le Beau MM et al. Prevalence of the inactivating 609C → T polymorphism in the NAD(P)H:qUinone oxidoreductase (NQO1) gene in patients with primary and therapy-related myeloid leukemia. Blood 1999; 94: 803-807.
    • (1999) Blood , vol.94 , pp. 803-807
    • Larson, R.A.1    Wang, Y.2    Banerjee, M.3    Wiemels, J.4    Hartford, C.5    Le Beau, M.M.6
  • 9
    • 0036802287 scopus 로고    scopus 로고
    • Identification of 127 amino acid substitution variants in screening 37 DNA repair genes in humans
    • Mohrenweiser HW, Xi T, Vazquez-Matias J, Jones IM. Identification of 127 amino acid substitution variants in screening 37 DNA repair genes in humans. Cancer Epidemiol Biomarkers Prev 2002; 11 (10, Part 1): 1054-1064.
    • (2002) Cancer Epidemiol Biomarkers Prev , vol.11 , Issue.10 and PART 1 , pp. 1054-1064
    • Mohrenweiser, H.W.1    Xi, T.2    Vazquez-Matias, J.3    Jones, I.M.4
  • 10
    • 18244378812 scopus 로고    scopus 로고
    • XRCC1 is required for DNA single-strand break repair in human cells
    • Brem R, Hall J. XRCC1 is required for DNA single-strand break repair in human cells. Nucleic Acids Res 2005; 33: 2512-2520.
    • (2005) Nucleic Acids Res , vol.33 , pp. 2512-2520
    • Brem, R.1    Hall, J.2
  • 11
    • 0029561598 scopus 로고
    • The glutathione S-transferase supergene family: Regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance
    • Hayes JD, Pulford DJ. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol 1995; 30: 445-600.
    • (1995) Crit Rev Biochem Mol Biol , vol.30 , pp. 445-600
    • Hayes, J.D.1    Pulford, D.J.2
  • 12
    • 0032864243 scopus 로고    scopus 로고
    • Genotype of glutathione S-transferase and other genetic configurations in myelodysplasia
    • Sasai Y, Horiike S, Misawa S, Kaneko H, Kobayashi M, Fujii H et al Genotype of glutathione S-transferase and other genetic configurations in myelodysplasia. Leuk Res 1999; 23: 975-981.
    • (1999) Leuk Res , vol.23 , pp. 975-981
    • Sasai, Y.1    Horiike, S.2    Misawa, S.3    Kaneko, H.4    Kobayashi, M.5    Fujii, H.6
  • 13
    • 0033954510 scopus 로고    scopus 로고
    • Glutathione S-transferase genotypes in children who develop treatment-related acute myeloid malignancies
    • Woo MH, Shuster JJ, Chen C, Bash RO, Behm FG, Camitta B et al. Glutathione S-transferase genotypes in children who develop treatment-related acute myeloid malignancies. Leukemia 2000; 14 232-237.
    • (2000) Leukemia , vol.14 , pp. 232-237
    • Woo, M.H.1    Shuster, J.J.2    Chen, C.3    Bash, R.O.4    Behm, F.G.5    Camitta, B.6
  • 14
    • 0035281735 scopus 로고    scopus 로고
    • Glutathione S-transferase polymorphisms and outcome of chemotherapy in childhood acute myeloid leukemia
    • Davies SM, Robison LL, Buckley JD, Tjoa T, Woods WG, Radloff GA et al. Glutathione S-transferase polymorphisms and outcome of chemotherapy in childhood acute myeloid leukemia. J Clin Oncol 2001; 19: 1279-1287.
    • (2001) J Clin Oncol , vol.19 , pp. 1279-1287
    • Davies, S.M.1    Robison, L.L.2    Buckley, J.D.3    Tjoa, T.4    Woods, W.G.5    Radloff, G.A.6
  • 15
    • 0033755155 scopus 로고    scopus 로고
    • Analysis of genetic polymorphism in NQO1, GST-M1, GST-T1, and CYP3A4 in 469 Japanese patients with therapy-related leukemia/myelodysplastic syndrome and de novo acute myeloid leukemia
    • Naoe T, Takeyama K, Yokozawa T, Kiyoi H, Seto M, Uike N et al. Analysis of genetic polymorphism in NQO1, GST-M1, GST-T1, and CYP3A4 in 469 Japanese patients with therapy-related leukemia/myelodysplastic syndrome and de novo acute myeloid leukemia. Clin Cancer Res 2000; 6: 4091-4095.
    • (2000) Clin Cancer Res , vol.6 , pp. 4091-4095
    • Naoe, T.1    Takeyama, K.2    Yokozawa, T.3    Kiyoi, H.4    Seto, M.5    Uike, N.6
  • 16
    • 0037377977 scopus 로고    scopus 로고
    • 5,10-Methylenetetrahydrofolate reductase polymorphisms and leukemia risk: A HuGE minireview
    • Robien K, Ulrich CM. 5,10-Methylenetetrahydrofolate reductase polymorphisms and leukemia risk: A HuGE minireview. Am J Epidemiol 2003; 157: 571-582.
    • (2003) Am J Epidemiol , vol.157 , pp. 571-582
    • Robien, K.1    Ulrich, C.M.2
  • 17
    • 22144446041 scopus 로고    scopus 로고
    • Effect of polymorphisms in folate-related genes on in vitro methotrexate sensitivity in pediatric acute lymphoblastic leukemia
    • de Jonge R, Hooijberg JH, van Zelst BD, Jansen G, van Zantwijk CH, Kaspers GJ et al. Effect of polymorphisms in folate-related genes on in vitro methotrexate sensitivity in pediatric acute lymphoblastic leukemia. Blood 2005; 106: 717-720.
    • (2005) Blood , vol.106 , pp. 717-720
    • de Jonge, R.1    Hooijberg, J.H.2    van Zelst, B.D.3    Jansen, G.4    van Zantwijk, C.H.5    Kaspers, G.J.6
  • 18
    • 19944428095 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase gene polymorphisms and response to fluorouracil-based treatment in advanced colorectal cancer patients
    • Etienne MC, Formento JL, Chazal M, Francoual M, Magne N, Formento P et al. Methylenetetrahydrofolate reductase gene polymorphisms and response to fluorouracil-based treatment in advanced colorectal cancer patients. Pharmacogenetics 2004; 14: 785-792.
    • (2004) Pharmacogenetics , vol.14 , pp. 785-792
    • Etienne, M.C.1    Formento, J.L.2    Chazal, M.3    Francoual, M.4    Magne, N.5    Formento, P.6
  • 19
    • 0037102580 scopus 로고    scopus 로고
    • The human XPC DNA repair gene: Arrangement, splice site information content and influence of a single nucleotide polymorphism in a splice acceptor site on alternative splicing and function
    • Khan SG, Muniz-Medina V, Shahlavi T, Baker CC, Inui H, Ueda T et al The human XPC DNA repair gene: Arrangement, splice site information content and influence of a single nucleotide polymorphism in a splice acceptor site on alternative splicing and function. Nucleic Acids Res 2002; 30: 3624-3631.
    • (2002) Nucleic Acids Res , vol.30 , pp. 3624-3631
    • Khan, S.G.1    Muniz-Medina, V.2    Shahlavi, T.3    Baker, C.C.4    Inui, H.5    Ueda, T.6
  • 21
    • 0034812088 scopus 로고    scopus 로고
    • XRCC1, XRCC3, XPD gene polymorphisms, smoking and (32)P-DNA adducts in a sample of healthy subjects
    • Matullo G, Palli D, Peluso M, Guarrera S, Carturan S, Celentano E et al. XRCC1, XRCC3, XPD gene polymorphisms, smoking and (32)P-DNA adducts in a sample of healthy subjects. Carcinogenesis 2001; 22: 1437-1445.
    • (2001) Carcinogenesis , vol.22 , pp. 1437-1445
    • Matullo, G.1    Palli, D.2    Peluso, M.3    Guarrera, S.4    Carturan, S.5    Celentano, E.6
  • 22
    • 0032721871 scopus 로고    scopus 로고
    • Polymorphisms of DNA repair gene XRCC1 in squamous cell carcinoma of the head and neck
    • Sturgis EM, Castillo EJ, Li L, Zheng R, Eicher SA, Clayman GL et al. Polymorphisms of DNA repair gene XRCC1 in squamous cell carcinoma of the head and neck. Carcinogenesis 1999; 20: 2125-2129.
    • (1999) Carcinogenesis , vol.20 , pp. 2125-2129
    • Sturgis, E.M.1    Castillo, E.J.2    Li, L.3    Zheng, R.4    Eicher, S.A.5    Clayman, G.L.6
  • 23
    • 33747827929 scopus 로고    scopus 로고
    • SNPStats: A web tool for the analysis of association studies
    • Sole X, Guino E, Valls J, Iniesta R, Moreno V. SNPStats: A web tool for the analysis of association studies. Bioinformatics 2006; 22 1928-1929.
    • (2006) Bioinformatics , vol.22 , pp. 1928-1929
    • Sole, X.1    Guino, E.2    Valls, J.3    Iniesta, R.4    Moreno, V.5
  • 24
    • 0036155283 scopus 로고    scopus 로고
    • Score tests for association between traits and haplotypes when linkage phase is ambiguous
    • Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA. Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet 2002; 70: 425-434.
    • (2002) Am J Hum Genet , vol.70 , pp. 425-434
    • Schaid, D.J.1    Rowland, C.M.2    Tines, D.E.3    Jacobson, R.M.4    Poland, G.A.5
  • 25
    • 0037276240 scopus 로고    scopus 로고
    • Genotype and haplotype distributions of MTHFR677C>T and 1298A>C single nucleotide polymorphisms: A meta-analysis
    • Ogino S, Wilson RB. Genotype and haplotype distributions of MTHFR677C>T and 1298A>C single nucleotide polymorphisms: A meta-analysis. J Hum Genet 2003; 48: 1-7.
    • (2003) J Hum Genet , vol.48 , pp. 1-7
    • Ogino, S.1    Wilson, R.B.2
  • 26
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
    • Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG et al A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase. Nat Genet 1995; 10: 111-113.
    • (1995) Nat Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3    Goyette, P.4    Sheppard, C.A.5    Matthews, R.G.6
  • 27
    • 0031971515 scopus 로고    scopus 로고
    • A second common mutation in the methylenetetrahydrofolate reductase gene: An additional risk factor for neuraltube defects?
    • van der Put NM, Gabreels F, Stevens EM, Smeitink JA, Trijbels FJ, Eskes TK et al. A second common mutation in the methylenetetrahydrofolate reductase gene: An additional risk factor for neuraltube defects? Am J Hum Genet 1998; 62: 1044-1051.
    • (1998) Am J Hum Genet , vol.62 , pp. 1044-1051
    • van der Put, N.M.1    Gabreels, F.2    Stevens, E.M.3    Smeitink, J.A.4    Trijbels, F.J.5    Eskes, T.K.6
  • 28
    • 0034743914 scopus 로고    scopus 로고
    • The 1298A → C polymorphism in methylenetetrahydrofolate reductase (MTHFR): In vitro expression and association with homocysteine
    • Weisberg IS, Jacques PF, Selhub J, Bostom AG, Chen Z, Curtis Ellison R et al. The 1298A → C polymorphism in methylenetetrahydrofolate reductase (MTHFR): in vitro expression and association with homocysteine. Atherosclerosis 2001; 156: 409-415.
    • (2001) Atherosclerosis , vol.156 , pp. 409-415
    • Weisberg, I.S.1    Jacques, P.F.2    Selhub, J.3    Bostom, A.G.4    Chen, Z.5    Curtis Ellison, R.6
  • 29
    • 33645925310 scopus 로고    scopus 로고
    • Structural perturbations in the Ala → Val polymorphism of methylenetetrahydrofolate reductase: How binding of folates may protect against inactivation
    • Pejchal R, Campbell E, Guenther BD, Lennon BW, Matthews RG, Ludwig ML. Structural perturbations in the Ala → Val polymorphism of methylenetetrahydrofolate reductase: How binding of folates may protect against inactivation. Biochemistry 2006; 45: 4808-4818.
    • (2006) Biochemistry , vol.45 , pp. 4808-4818
    • Pejchal, R.1    Campbell, E.2    Guenther, B.D.3    Lennon, B.W.4    Matthews, R.G.5    Ludwig, M.L.6
  • 30
    • 0034808335 scopus 로고    scopus 로고
    • Lievers KJ, Boers GH, Verhoef P, den Heijer M, Kluijtmans LA, van der Put NM et al. A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk. J Mol Med 2001; 79: 522-528.
    • Lievers KJ, Boers GH, Verhoef P, den Heijer M, Kluijtmans LA, van der Put NM et al. A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk. J Mol Med 2001; 79: 522-528.
  • 31
    • 1042292043 scopus 로고    scopus 로고
    • Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate
    • Sohn KJ, Croxford R, Yates Z, Lucock M, Kim YI. Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate. J Natl Cancer Inst 2004; 96: 134-144.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 134-144
    • Sohn, K.J.1    Croxford, R.2    Yates, Z.3    Lucock, M.4    Kim, Y.I.5
  • 32
    • 14944380124 scopus 로고    scopus 로고
    • Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphism in normal tissue as predictors of fluorouracil sensitivity
    • Jakobsen A, Nielsen JN, Gyldenkerne N, Lindeberg J. Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphism in normal tissue as predictors of fluorouracil sensitivity. J Clin Oncol 2005; 23: 1365-1369.
    • (2005) J Clin Oncol , vol.23 , pp. 1365-1369
    • Jakobsen, A.1    Nielsen, J.N.2    Gyldenkerne, N.3    Lindeberg, J.4
  • 33
    • 18844408403 scopus 로고    scopus 로고
    • MTHFR genotypes and breast cancer survival after surgery and chemotherapy: A report from the Shanghai Breast Cancer Study
    • Shrubsole MJ, Shu XO, Ruan ZX, Cai Q, Cai H, Niu Q et al. MTHFR genotypes and breast cancer survival after surgery and chemotherapy: A report from the Shanghai Breast Cancer Study. Breast Cancer Res Treat 2005; 91: 73-79.
    • (2005) Breast Cancer Res Treat , vol.91 , pp. 73-79
    • Shrubsole, M.J.1    Shu, X.O.2    Ruan, Z.X.3    Cai, Q.4    Cai, H.5    Niu, Q.6
  • 34
    • 0032573077 scopus 로고    scopus 로고
    • A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells
    • Bagley PJ, Selhub J. A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells. Proc Natl Acad Sci USA 1998; 95: 13217-13220.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13217-13220
    • Bagley, P.J.1    Selhub, J.2
  • 35
    • 0037117501 scopus 로고    scopus 로고
    • A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status
    • Friso S, Choi SW, Girelli D, Mason JB, Dolnikowski GG, Bagley PJ et al. A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status. Proc Natl Acad Sci USA 2002; 99: 5606-5611.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 5606-5611
    • Friso, S.1    Choi, S.W.2    Girelli, D.3    Mason, J.B.4    Dolnikowski, G.G.5    Bagley, P.J.6
  • 36
    • 85014294446 scopus 로고    scopus 로고
    • Polymorphisms in methylenetetrahydrofolate reductase and methotrexate sensitivity in childhood acute lymphoblastic leukemia
    • Taub JW, Matherly LH, Ravindranath Y, Kaspers GJ, Rots MG, Zantwijk CH. Polymorphisms in methylenetetrahydrofolate reductase and methotrexate sensitivity in childhood acute lymphoblastic leukemia. Leukemia 2002; 16: 764-765.
    • (2002) Leukemia , vol.16 , pp. 764-765
    • Taub, J.W.1    Matherly, L.H.2    Ravindranath, Y.3    Kaspers, G.J.4    Rots, M.G.5    Zantwijk, C.H.6
  • 37
    • 0036928840 scopus 로고    scopus 로고
    • Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukemia patients intolerant to methotrexate
    • Chiusolo P, Reddiconto G, Casorelli I, Laurenti L, Sora F, Mele L et al. Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukemia patients intolerant to methotrexate. Ann Oncol 2002; 13: 1915-1918.
    • (2002) Ann Oncol , vol.13 , pp. 1915-1918
    • Chiusolo, P.1    Reddiconto, G.2    Casorelli, I.3    Laurenti, L.4    Sora, F.5    Mele, L.6
  • 38
    • 33646677710 scopus 로고    scopus 로고
    • MTHFR 677 (C → T) polymorphism is not relevant for prognosis or therapy-associated toxicity in pediatric NHL: Results from 484 patients of multicenter trial NHL-BFM 95
    • Seidemann K, Book M, Zimmermann M, Meyer U, Welte K, Stanulla M et al. MTHFR 677 (C → T) polymorphism is not relevant for prognosis or therapy-associated toxicity in pediatric NHL: Results from 484 patients of multicenter trial NHL-BFM 95. Ann Hematol 2006; 85: 291-300.
    • (2006) Ann Hematol , vol.85 , pp. 291-300
    • Seidemann, K.1    Book, M.2    Zimmermann, M.3    Meyer, U.4    Welte, K.5    Stanulla, M.6
  • 39
    • 33746972784 scopus 로고    scopus 로고
    • Folate cycle gene variants and chemotherapy toxicity in pediatric patients with acute lymphoblastic leukemia
    • Costea I, Moghrabi A, Laverdiere C, Graziani A, Krajinovic M. Folate cycle gene variants and chemotherapy toxicity in pediatric patients with acute lymphoblastic leukemia. Haematologica 2006; 91: 1113-1116.
    • (2006) Haematologica , vol.91 , pp. 1113-1116
    • Costea, I.1    Moghrabi, A.2    Laverdiere, C.3    Graziani, A.4    Krajinovic, M.5
  • 40
    • 33644987431 scopus 로고    scopus 로고
    • MLL gene rearrangements have no direct impact on Ara-C sensitivity in infant acute lymphoblastic leukemia and childhood M4/M5 acute myeloid leukemia
    • Stam RW, Hubeek I, den Boer ML, Buijs-Gladdines JG, Creutzig U, Kaspers GJ et al. MLL gene rearrangements have no direct impact on Ara-C sensitivity in infant acute lymphoblastic leukemia and childhood M4/M5 acute myeloid leukemia. Leukemia 2006; 20: 179-182.
    • (2006) Leukemia , vol.20 , pp. 179-182
    • Stam, R.W.1    Hubeek, I.2    den Boer, M.L.3    Buijs-Gladdines, J.G.4    Creutzig, U.5    Kaspers, G.J.6
  • 41
    • 4444317848 scopus 로고    scopus 로고
    • Regulation of Vinca alkaloid-induced apoptosis by NF-kappaB/IkappaB pathway in human tumor cells
    • Huang Y, Fang Y, Wu J, Dziadyk JM, Zhu X, Sui M et al. Regulation of Vinca alkaloid-induced apoptosis by NF-kappaB/IkappaB pathway in human tumor cells. Mol Cancer Ther 2004; 3: 271-277.
    • (2004) Mol Cancer Ther , vol.3 , pp. 271-277
    • Huang, Y.1    Fang, Y.2    Wu, J.3    Dziadyk, J.M.4    Zhu, X.5    Sui, M.6
  • 42
    • 28244472301 scopus 로고    scopus 로고
    • Regulatory studies of murine methylenetetrahydrofolate reductase reveal two major promoters and NF-kappaB sensitivity
    • Pickell L, Tran P, Leclerc D, Hiscott J, Rozen R. Regulatory studies of murine methylenetetrahydrofolate reductase reveal two major promoters and NF-kappaB sensitivity. Biochim Biophys Acta 2005; 1731: 104-114.
    • (2005) Biochim Biophys Acta , vol.1731 , pp. 104-114
    • Pickell, L.1    Tran, P.2    Leclerc, D.3    Hiscott, J.4    Rozen, R.5


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