Thrombophilia and antithrombotic therapy in women with recurrent spontaneous abortions

Journal of Reproductive Medicine for the Obstetrician and Gynecologist

Volumn 52, Issue 6, 2007, Pages 499-502

  Deligiannidis, Aristidis ^a,b   Parapanissiou, Efthimia ^a   Mavridis, Panagiotis ^a   Tabakoudis, George ^a   Mavroudi, Antigoni ^a   Papastavrou, Theodouli ^a   Tabakoudis, Panagiotis ^a  

^a Aristotle University of Thessaloniki   (Greece)

^b NONE   (Greece)

Author keywords

Abortion, recurrent; Antiphospholipid antibodies; Thrombophilia

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; ENOXAPARIN; LOW MOLECULAR WEIGHT HEPARIN; PHOSPHOLIPID ANTIBODY;

ABORTION; ADULT; ANTICOAGULANT THERAPY; ARTICLE; CONTROLLED STUDY; DRUG CHOICE; DRUG EFFICACY; FEMALE; HEMATOLOGICAL PARAMETERS; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; PREGNANCY; PRIORITY JOURNAL; RECOMMENDED DRUG DOSE; RECURRENT ABORTION; SCREENING TEST; SPONTANEOUS ABORTION; THROMBOPHILIA; THROMBOSIS; TREATMENT OUTCOME;

EID: 34250866173     PISSN: 00247758     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Chong P, Matzner W, Ching W: Immunology of recurrent spontaneous abortions. Female Patient 1995;20:1-4
2. Eldor A: Thrombophilia and its treatment in pregnancy. J Thrombolysis 2001;12:23-30
3. Bonnar J: Can more be done in obstetric and gynecologic practice to reduce morbidity and mortality associated with venous thromboembolism? Am J Obstet Gynecol 1999;180: 784-791
4. Martinelli I, Taioli E, Cetin I, et al: Mutations in coagulation factors in women with unexplained late fetal loss. N Engl J Med 2000;343:1015-1018
5. Levine J, Branch W, Rauch J: The antiphospholipid syndrome. N Engl J Med 2002;346:752-763
6. Khamashta MA: Management of thrombosis and pregnancy loss in the antiphospholipid syndrome. Lupus (suppl 2) 1998;7:S162-S165
7. Kupferminc MJ, Fait G, Many A, et al: Severe preeclampsia and high frequency of genetic thrombophilic mutations. Obstet Gynecol 2000;96:45-49
8. Seligsohn U, Lubetski Ah. Genetic susceptibility to venous thrombosis. N Engl Med 2001;344:1222-1231
9. Yamada H, Kato EH, Kobashi G, et al: Recurrent pregnancy loss: Etiology of thrombophilia. Semin Thromb Hemost 2001;27:121-129
10. Buchholz T, Thaler CJ: Inherited thrombophilia: Impact on human reproduction. Am J Reprod Immunol 2003; 50:20-32
11. Eldor A: Thrombophilia and its treatment in pregnancy. J Thromb Thrombolysis 2001;12:23-30
12. Regan L, Rai R: Thrombophilia and pregnancy loss. J Reprod Immunol 2002;55:163-180
13. Preston FE, Rosendaal FR, Walker ID, et al: Increased fetal loss in women with heritable thrombophilia. Lancet 1996;348:913-916
14. Sanson BJ, Fredierich PW, Simioni P, et al: The risk of abortion and stillbirth in antithrombin, protein C, protein S-deficient women. Thromb Haemost 1996;75:387-388
15. Ridker PM, Mileyich JP, Buring JE, et al: Factor V Leiden mutation as a risk factor for recurrent pregnancy loss. Ann Intern Med 1998;128:1000-1003
16. Cleary-Goldman J, Nakhuda GS, Zimmermann RC, et al: The role of factor V Leiden mutation in recurrent pregnancy loss. J Am Med Womens Assoc 2003;58:165-172
17. Gibson PS, Rosene Montella K: Drugs in pregnancy: Anticoagulants. Best Pract Res Clin Obstet Gynaecol 2001;15:847-861
18. Sarto A, Rocha M, Geller M, et al: Treatment with enoxaparin adapted to the fertility programs in women with recurrent abortion and thrombophilia. Medicina 2001;61:406-412
19. Bar J, Cohen-Sacher B, Hod M, et al: Low-molecular thrombophilia in pregnant women. Int J Gynaecol Obstet 2000;69: 209-213
20. Riyazi N, Leeda M, de Vries J, et al: Low-molecular-weight heparin combined with aspirin in pregnant women with thrombophilia and a history of preeclampsia or fetal growth restriction: A preliminary study. Eur J Obstet Gynecol Reprod Biol 1998;80:49-54
21. Eldor A: Thrombophilia, thrombosis and pregnancy. Thromb Haemost 2001;86:104-111
22. Bar J, Mashiah R, Cohen Sacher B, et al: Effect of thrombophylaxis on uterine and fetal circulation in pregnant women with a history of pregnancy complications. Thromb Res 2001;191:235-241