Effects of diet with or without exercise on leptin and anticoagulation proteins levels in obesity

Blood Coagulation and Fibrinolysis

Volumn 18, Issue 5, 2007, Pages 389-394

  Murakami, Takashi ^a,b   Horigome, Hitoshi ^a   Tanaka, Kiyoji ^a   Nakata, Yoshio ^a   Katayama, Yasutomi ^a   Matsui, Akira ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b Ibaraki Children's Hospital   (Japan)

Author keywords

Aerobic exercise; Calorie restricted diet; Protein C; Protein S; Weight reduction

Indexed keywords

LEPTIN; PROTEIN C; PROTEIN S;

ADULT; AEROBIC EXERCISE; ANTICOAGULATION; ARTICLE; BODY FAT; BODY MASS; BODY WEIGHT; CALORIC RESTRICTION; CARDIOVASCULAR DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DIET THERAPY; EXERCISE; FEMALE; HUMAN; MALE; OBESITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SYSTOLIC BLOOD PRESSURE; THROMBOEMBOLISM; WAIST CIRCUMFERENCE; WEIGHT REDUCTION;

ADULT; BODY MASS INDEX; DIET; EXERCISE; FEMALE; HUMANS; LEPTIN; MALE; MIDDLE AGED; OBESITY; PROTEIN C; PROTEIN S; RISK FACTORS; THROMBOEMBOLISM; TIME FACTORS;

EID: 34250866135     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mbc.0000278929.87251.5d     Document Type: Article

References (32)

1. Rao SV, Donahue M, Pi-Sunyer FX, Fuster V. Results of expert meetings: obesity and cardiovascular disease. Obesity as a risk factor in coronary artery disease. Am Heart J 2001; 142:1102-1107.
2. Ambrose JA, Weinrauch M. Thrombosis in ischemic heart disease. Arch Intern Med 1996; 156:1382-1394.
3. Rosito GA, D'Agostino RB, Massaro J, Lipinska I, Mittleman MA, Sutherland P, et al. Association between obesity and a prothrombotic state: the Framingham Offspring Study. Thromb Haemost 2004; 91:683-689.
4. Mertens I, Van Gaal LF. Obesity, haemostasis and the fibrinolytic system. Obes Rev 2002; 3:85-101.
5. Steinberg HO, Chaker H, Leaming R, Johnson A, Brechtel G, Baron AD. Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J Clin Invest 1996; 97:2601-2610.
6. Mavri A, Stegnar M, Krebs M, Sentocnik JT, Geiger M, Binder BR. Impact of adipose tissue on plasma plasminogen activator inhibitor-1 in dieting obese women. Arterioscler Thromb Vasc Biol 1999; 19:1582-1587.
7. Charles MA, Morange P, Eschwege E, Andre P, Vague P, Juhan-Vague I. Effect of weight change and metformin on fibrinolysis and the von Willebrand factor in obese nondiabetic subjects: the BIGPRO1 Study. Biguanides and the prevention of the risk of obesity. Diabetes Care 1998; 21:1967-1972.
8. Meckling KA, O'Sullivan C, Saari D. Comparison of a low-fat diet to a low-carbohydrate diet on weight loss, body composition, and risk factors for diabetes and cardiovascular disease in free-living, overweight men and women. J Clin Endocrinol Metab 2004; 89:2717-2723.
9. Lindahl B, Nilsson TK, Jansson JH, Asplund K, Hallmans G. Improved fibrinolysis by intense lifestyle intervention. A randomized trial in subjects with impaired glucose tolerance. J Intern Med 1999; 246:105-112.
10. Hamdy O, Ledbury S, Mullooly C, Jarema C, Porter S, Ovalle K, et al. Lifestyle modification improves endothelial function in obese subjects with the insulin resistance syndrome. Diabetes Care 2003; 26:2119-2125.
11. Marlar RA, Kleiss AJ, Griffin JH. Mechanism of action of human activated protein C, a thrombin-dependent anticoagulant enzyme. Blood 1982; 59:1067-1072.
12. Walker FJ. Regulation of activated protein C by protein S. The role of phospholipid in factor Va inactivation. J Biol Chem 1981; 256:11128-11131.
13. Bowles LK, Cooper JA, Howarth DJ, Miller GJ, MacCallum PK. Associations of haemostatic variables with body mass index: a community-based study. Blood Coagul Fibrinolysis 2003; 14:569-573.
14. Cucuianu M, Brudasca I, Trif I, Stancu A. Clinical studies on plasma protein C. Correlation with serum cholinesterase. Nouv Rev Fr Hematol 1993; 35:481-486.
15. Godsland IF, Crook D, Proudler AJ, Stevenson JC. Hemostatic risk factors and insulin sensitivity, regional body fat distribution, and the metabolic syndrome. J Clin Endocrinol Metab 2005; 90:190-197.
16. Brudasca I, Cucuianu M, Stancu A, Colhon DM. Plasma protein S-antigen (PS:Ag) in selected disease states. Rom J Intern Med 1994; 32:29-35.
17. Okura T, Nakata Y, Yamabuki K, Tanaka K. Regional body composition changes exhibit opposing effects on coronary heart disease risk factors. Arterioscler Thromb Vasc Biol 2004; 24:923-929.
18. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults - the evidence report. National Institutes of Health. Obes Res 1998; 6(Suppl 2):51S-209S.
19. Guerre-Millo M. Adipose tissue and adipokines: for better or worse. Diabetes Metab 2004; 30:13-19.
20. Ziccardi P, Nappo F, Giugliano G, Esposito K, Marfella R, Cioffi M, et al. Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year. Circulation 2002; 105:804-809.
21. Monzillo LU, Hamdy O, Horton ES, Ledbury S, Mullooly C, Jarema C, et al. Effect of lifestyle modification on adipokine levels in obese subjects with insulin resistance. Obes Res 2003; 11:1048-1054.
22. Guagnano MT, Romano M, Falco A, Nutini M, Marinopiccoli M, Manigrasso MR, et al. Leptin increase is associated with markers of the hemostatic system in obese healthy women. J Thromb Haemost 2003; 1:2330-2334.
23. Minocci A, Savia G, Lucantoni R, Berselli ME, Tagliaferri M, Calo G, et al. Leptin plasma concentrations are dependent on body fat distribution in obese patients. Int J Obes Relat Metab Disord 2000; 24:1139-1144.
24. Shimizu H, Shimomura Y, Hayashi R, Ohtani K, Sato N, Futawatari T, et al. Serum leptin concentration is associated with total body fat mass, but not abdominal fat distribution. Int J Obes Relat Metab Disord 1997; 21:536-541.
25. Thong FS, Hudson R, Ross R, Janssen I, Graham TE. Plasma leptin in moderately obese men: independent effects of weight loss and aerobic exercise. Am J Physiol Endocrinol Metab 2000; 279:E307-E313.
26. Reseland JE, Anderssen SA, Solvoll K, Hjermann I, Urdal P, Holme I, et al. Effect of long-term changes in diet and exercise on plasma leptin concentrations. Am J Clin Nutr 2001; 73:240-245.
27. Pasman WJ, Westerterp-Plantenga MS, Saris WH. The effect of exercise training on leptin levels in obese males. Am J Physiol 1998; 274:E280-E286.
28. De Pergola G, De Mitrio V, Giorgino F, Sciaraffia M, Minenna A, Di Bari L, et al. Increase in both pro-thrombotic and anti-thrombotic factors in obese premenopausal women: relationship with body fat distribution. Int J Obes Relat Metab Disord 1997; 21:527-535.
29. Primrose JN, Davies JA, Prentice CR, Hughes R, Johnston D. Reduction in factor VII, fibrinogen and plasminogen activator inhibitor-1 activity after surgical treatment of morbid obesity. Thromb Haemost 1992; 68:396-399.
30. Folsom AR, Qamhieh HT, Wing RR, Jeffery RW, Stinson VL, Kuller LH, et al. Impact of weight loss on plasminogen activator inhibitor (PAI-1), factor VII, and other hemostatic factors in moderately overweight adults. Arterioscler Thromb 1993; 13:162-169.
31. Svendsen OL, Hassager C, Christiansen C, Nielsen JD, Winther K. Plasminogen activator inhibitor-1, tissue-type plasminogen activator, and fibrinogen: effect of dieting with or without exercise in overweight postmenopausal women. Arterioscler Thromb Vasc Biol 1996; 16:381-385.
32. Barbeau P, Litaker MS, Woods KF, Lemmon CR, Humphries MC, Owens S, et al. Hemostatic and inflammatory markers in obese youths: effects of exercise and adiposity. J Pediatr 2002; 141:415-420.