Coincident activation of Th2 T cells with onset of the disease and differential expression of GRO-gamma in peripheral blood leukocytes in minimal change disease

American Journal of Nephrology

Volumn 27, Issue 3, 2007, Pages 253-261

  Adrogue, Horacio E ^a   Borillo, Jason ^a   Torres, Lisa ^b   Kale, Arundhati ^a   Zhou, Cindy ^b   Feig, Daniel ^a   Merszei, Justin ^a   Johnson, Richard ^c   Lou, Ya Huan ^b  

^a HOUSTON METHODIST HOSPITAL   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Chemokine; Growth related oncogene ; Minimal change disease; Th2 T cell activation

Indexed keywords

ALPHA CHEMOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 4; MELANOMA GROWTH STIMULATORY ACTIVITY FACTOR; MESSENGER RNA; RNA; CD4 ANTIGEN; CD69 ANTIGEN; CXCL3 PROTEIN, HUMAN; CYTOKINE; LEUKOCYTE ANTIGEN; T LYMPHOCYTE ANTIGEN; UNCLASSIFIED DRUG;

ARTICLE; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CELL FUNCTION; CELL ISOLATION; CHILD; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; FLOW CYTOMETRY; GLOMERULUS FILTRATION; HUMAN; LEUKOCYTE; LYMPHOCYTE SUBPOPULATION; MALE; MICROARRAY ANALYSIS; MINIMAL CHANGE DISEASE; NEPHROSIS; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL ANALYSIS; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH2 CELL; CASE CONTROL STUDY; GENE EXPRESSION; GLOMERULUS BASEMENT MEMBRANE; IMMUNOLOGY; LIPOID NEPHROSIS; LYMPHOCYTE ACTIVATION; METABOLISM; PERMEABILITY; PHYSIOLOGY; PRESCHOOL CHILD;

ANTIGENS, CD; ANTIGENS, CD4; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CASE-CONTROL STUDIES; CD4 LYMPHOCYTE COUNT; CHEMOKINES, CXC; CHILD; CHILD, PRESCHOOL; CYTOKINES; FEMALE; GENE EXPRESSION; GLOMERULAR BASEMENT MEMBRANE; HUMANS; LYMPHOCYTE ACTIVATION; MALE; NEPHROSIS, LIPOID; PERMEABILITY; TH2 CELLS;

EID: 34250837386     PISSN: 02508095     EISSN: None     Source Type: Journal    
DOI: 10.1159/000101371     Document Type: Article

References (38)

1. Mason PD: Minimal change disease and primary focal segmental glomerulonephritis; in Johnson RJ (ed): Comprehensive Clinical Nephrology. London, Mosby, 2000, pp 22.1-22.10.
2. Johnson RJ, Hurtado A, Merszei J, Rodriguez-Iturbe B, Feng L: Hypothesis: dysregulation of immunologic balance resulting from hygiene and socioeconomic factors may influence the epidemiology and cause of glomerulonephritis worldwide. Am J Kidney Dis 2003;42:575-581.
3. Karabay-Bayazit A, Noyan A, Bayazit Y, Ozel A, Anarat A: HLAs in children with minimal change disease and other types of nephrotic syndrome in the southern part of Turkey. Turk J Pediatr 2001;43:24-28.
4. Haas M, Meehan SM, Karrison TG, Spargo BH: Changing etiologies of unexplained adult nephrotic syndrome: a comparison of renal biopsy findings from 1976-1979 and 1995-1997. Am J Kidney Dis 1997;30:621-631.
5. Shalhoub RJ: Pathogenesis of lipoid nephrosis: a disorder of T-cell function. Lancet 1974;ii:556-560.
6. Eyres K, Mallick NP, Taylor G: Evidence for cell-mediated immunity to renal antigens in minimal-change nephrotic syndrome. Lancet 1976;i:1158-1159.
7. Sasdelli M, Cagnoli L, Candi P, Mandreoli M, Beltrandi E, Zucchelli P: Cell mediated immunity in idiopathic glomerulonephritis. Clin Exp Immunol 1981;46:27-34.
8. Hurtado A, Johnson RJ: Hygiene hypothesis and prevalence of glomerulonephritis. Kidney Int Suppl 2005;97:S62-S67.
9. Bernstein J Jr, Edelmann CM Jr: Minimal change nephrotic syndrome: histopathology and steroid-responsiveness. Arch Dis Child 1982;57:816-817.
10. Peces R, Sanchez L, Gorostidi M, Alvarez J: Minimal change nephrotic syndrome associated with Hodgkin's lymphoma. Nephrol Dial Transplant 1991;6:155-158.
11. Stewart AW, Mitchell EA, Pearce N, Strachan DP, Weilandon SK: ISAAC Steering Committee: International Study for Asthma and Allergy in Childhood: The relationship of per capita gross national product to the prevalence of symptoms of asthma and other atopic diseases in children (ISAAC). Int J Epidemiol 2001;30:173-179.
12. Masutani K, Taniguchi M, Nakashima H, Yotsueda H. Kudoh Y, Tsuruya K, et al: Upregulated interleukin-4 production by peripheral T-helper cells in idiopathic membranous nephropathy. Nephrol Dial Transplant 2004;19:580-586.
13. Valanciute A, le Gouvello S, Solhonne B, Pawlak A, Grimbert P, Lyonnet L, et al: NF-κ B p65 antagonizes IL-4 induction by c-maf in minimal change nephrotic syndrome. J Immunol 2004;172:688-698.
14. Shimoyama H, Nakajima M, Naka H, Maruhashi Y, Akazawa H, Ueda T, et al: Upregulation of interleukin-2 mRNA in children with idiopathic nephrotic syndrome. Pediatr Nephrol 2004;19:1115-1121.
15. Lama G, Luongo I, Tirino G, Borriello A, Carangio C, Salsano ME: T-lymphocyte populations and cytokines in childhood nephrotic syndrome. Am J Kidney Dis 2002;39:958-965.
16. Yap HK, Cheung W, Murugasu B, Sim SK, Seah CC, Jordan SC: Th1 and Th2 cytokine mRNA profiles in childhood nephrotic syndrome: evidence for increased IL-13 mRNA expression in relapse. J Am Soc Nephrol 1999;10:529-537.
17. Kumar J, Gulati S, Sharma AP, Sharma RK, Gupta RK: Histopathological spectrum of childhood nephrotic syndrome in Indian children. Pediatr Nephrol 2003;18:657-660.
18. Turner KJ: Epidemiology of the allergic response. Ciba Found Symp 1989;147:205-222.
19. Koyama A, Fujisaki M, Kobayashi M, Igarashi M, Narita M: A glomerular permeability factor produced by human T cell hybridomas. Kidney Int 1991;40:453-460.
20. Tesar V, Zima T, Kalousova M: Pathobiochemistry of nephrotic syndrome. Adv Clin Chem 2003;37:173-218.
21. Haskill S, Peace A, Morris J, Sporn SA, Anisowicz A, Lee SW, et al: Identification of three related human GRO genes encoding cytokine functions. Proc Natl Acad Sci USA 1990;87:7732-7736.
22. Shintani S, Ishikawa T, Nonaka T, Li C, Nakashiro K, Wong DTW, et al: Growth-related oncogene-1 expression is associated with angiogenesis and lymph node metastasis in human oral cancer. Oncology 2004;66:316-322.
23. Anisowicz A, Bardwell L, Sager R: Constitutive overexpression of a growth-regulated gene in transformed Chinese hamster and human cells. Proc Natl Acad Sci USA 1987;84:7188-7192.
24. Wolpe SD, Sherry B, Juers D, Davatelis G, Yurt RW, Cerami A: Identification and characterization of macrophage inflammatory protein 2. Proc Natl Acad Sci USA 1989;86:612-616.
25. Acres RB, Conlon PJ, Mochizuki DY, Gallis B: Rapid phosphorylation and modulation of the T4 antigen on cloned helper T cells induced by phorbol myristate acetate or antigen. J Biol Chem 1986;261:16210-16214.
26. Zachwieja J, Bobkowski W, Dobrowolska-Zachwieja A, Lewandowska-Stachowiak M, Zaniew M, Maciejewski J: Intracellular cytokines of peripheral blood lymphocytes in nephrotic syndrome. Pediatr Nephrol 2002;17:733-740.
27. + T cells through IL-12 produced by Listeria-induced macrophages. Science 1993;260:547-549.
28. Le Berre L, Herve C, Buzelin F, Usal C, Soulillou JP, Dantal J: Renal macrophage activation and Th2 polarization precedes the development of nephrotic syndrome in Buffalo/Mna rats. Kidney Int 2005;68:2079-2090.
29. Zola H: Markers of cell lineage, differentiation and activation. J Biol Regul Homeostat Agents 2000;14:218-219.
30. Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M: Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995;155:1151-1164.
31. Karras A, de Montpreville V, Fakhouri F, Grunfeld JP, Lesavre P; Groupe d'Etudes des Nephropathies Associées aux Thymomes: Renal and thymic pathology in thymoma-associated nephropathy: report of 21 cases and review of the literature. Nephrol Dial Transplant 2005;20:1075-1082.
32. Cao Y, Chen C, Weatherbee JA, Tsang M, Folkman J: GRO-β, a -C-X-C-chemokine, is an angiogenesis inhibitor that suppresses the growth of Lewis lung carcinoma in mice. J Exp Med 1995;182:2069-2077.
33. Schwartz D, Andalibi A, Chaverri-Almada L, Berliner JA, Kirchgessner T, Fang ZT, et al: Role of the GRO family of chemokines in monocyte adhesion to MM-LDL-stimulated endothelium. J Clin Invest 1994;94:1968-1973.
34. Miura M, Fu X, Zhang QW, Remick DG, Fairchild RL: Neutralization of Gro-α and macrophage inflammatory protein-2 attenuates renal ischemia/reperfusion injury. Am J Pathol 2001;159:2137-2145.
35. Belperio JA, Keane MP, Burdick MD, Londhe V, Xue YY, Li K, et al: Critical role for CXCR2 and CXCR2 ligands during the pathogenesis of ventilator-induced lung injury. J Clin Invest 2002;110:1703-1716.
36. Okahara S, Arimura Y, Yabana T, Kobayashi K, Gotoh A, Motoya S, et al: Inflammatory gene signature in ulcerative colitis with cDNA macroarray analysis. Aliment Pharmacol Ther 2005;21:1091-1097.
37. Casolaro V, Georas SN, Song Z, Zubkoff ID, Abdulkadir SA, Thanos D, et al: Inhibition of NF-AT-dependent transcription by NF-κB: implications for differential gene expression in T helper cell subsets. Proc Natl Acad Sci USA 1995;92:11623-11627.
38. Anisowicz A, Messineo M, Lee SW, Sager R: An NF-kappa B-like transcription factor mediates IL-1/TNF-alpha induction of GRO in human fibroblasts. J Immunol 1991;147:520-527.