Fibulin-1C and Fibulin-1D splice variants have distinct functions and assemble in a hemicentin-dependent manner

Development

Volumn 132, Issue 19, 2005, Pages 4223-4234

  Muriel, Joaquin M ^a   Dong, Chun ^a   Hutter, Harald ^b   Vogel, Bruce E ^a  

^a UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^b MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

Basement membrane; C. elegans; Cell adhesion; Extracellular matrix; Hemidesmosome

Indexed keywords

FIBULIN; FIBULIN 1C; FIBULIN 1D; HEMICENTIN; IMMUNOGLOBULIN; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; BASEMENT MEMBRANE; CAENORHABDITIS ELEGANS; CELL ADHESION; CELL SHAPE; CONTROLLED STUDY; EXTRACELLULAR SPACE; GENETIC CONSERVATION; GENETIC VARIABILITY; GONAD DEVELOPMENT; MORPHOGENESIS; MUSCLE DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGANOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE;

ABDOMINAL MUSCLES; ALTERNATIVE SPLICING; ANIMALS; BASEMENT MEMBRANE; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CALCIUM-BINDING PROTEINS; CELL ADHESION; CELL SHAPE; GONADS; INTESTINES; MEMBRANE PROTEINS; MICROSCOPY, ELECTRON, TRANSMISSION; MORPHOGENESIS; MUTATION; PHARYNX;

CAENORHABDITIS ELEGANS; METAZOA; VERTEBRATA;

EID: 27644458288     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.02007     Document Type: Article

References (26)

1. Argraves, W. S., Greene, L. M., Cooley, M. A. and Gallagher, W. M. (2003). Fibulins: physiological and disease perspectives. EMBO Rep. 4, 1127-1131.
2. Barth, J. L., Argraves, K. M., Roark, E. F., Little, C. D. and Argraves, W. S. (1998). Identification of chicken and C. elegans fibulin-1 homologs and characterization of the C. elegans fibulin-1 gene. Matrix Biol. 17, 635-646.
3. Chalfie, M. and Sulston, J. (1981). Developmental genetics of the mechanosensory neurons of Caenorhabditis elegans. Dev. Biol. 82, 358-370.
4. Chu, M. L. and Tsuda, T. (2004). Fibulins in development and heritable disease. Birth Defects Res. 72, 25-36.
5. Debeer, P., Schoenmakers, E. F., Twal, W. O., Argraves, W. S., De Smet, L., Fryns, J. P. and Van De Ven, W. J. (2002). The fibulin-1 gene (FBLN1) is disrupted in a t(12;22) associated with a complex type of synpolydactyly. J. Med. Genet. 39, 98-104.
6. Edgley, M., D'Souza, A., Moulder, G., McKay, S., Shen, B., Gilchrist, E., Moerman, D. and Barstead, R. (2002). Improved detection of small deletions in complex pools of DNA. Nucleic Acids Res. 30, e52.
7. Emtage, L., Gu, G., Hartwieg, E. and Chalfie, M. (2004). Extracellular proteins organize the mechanosensory channel complex in C. elegans touch receptor neurons. Neuron 44, 795-807.
8. Grassel, S., Sicot, F. X., Gotta, S. and Chu, M. L. (1999). Mouse fibulin-2 gene. Complete exon-intron organization and promoter characterization. Eur. J. Biochem. 263, 471-477.
9. Hall, D. H. (1995). Electron microscopy and three-dimensional image reconstruction. Methods Cell Biol. 48, 396-436.
10. Hedgecock, E. M., Culotti, J. G., Hall, D. H. and Stern, B. D. (1987). Genetics of cell and axon migrations in Caenorhabditis elegans. Development 100, 365-382.
11. Hesselson, D., Newman, C., Kim, K. W. and Kimble, J. (2004). GON-1 and fibulin have antagonistic roles in control of organ shape. Curr. Biol. 14, 2005-2010.
12. Huang, C. C., Hall, D. H., Hedgecock, E. M., Kao, G., Karantza, V., Vogel, B. E., Hutter, H., Chisholm, A. D., Yurchenco, P. D. and Wadsworth, W. G. (2003). Laminin alpha subunits and their role in C. elegans development. Development 130, 3343-3358.
13. Kostka, G., Giltay, R., Bloch, W., Addicks, K., Timpl, R., Fassler, R. and Chu, M. L. (2001). Perinatal lethality and endothelial cell abnormalities in several vessel compartments of fibulin-1-deficient mice. Mol. Cell. Biol. 21, 7025-7034.
14. Kubota, Y., Kuroki, R. and Nishiwaki, K. (2004). A fibulin-1 homolog interacts with an ADAM protease that controls cell migration in C. elegans. Curr. Biol. 14, 2011-2018.
15. Lecka-Czernik, B., Lumpkin, C. K., Jr and Goldstein, S. (1995). An overexpressed gene transcript in senescent and quiescent human fibroblasts encoding a novel protein in the epidermal growth factor-like repeat family stimulates DNA synthesis. Mol. Cell. Biol. 15, 120-128.
16. Moll, F., Katsaros, D., Lazennec, G., Hellio, N., Roger, P., Giacalone, P. L., Chalbos, D., Maudelonde, T., Rochefort, H. and Pujol, P. (2002). Estrogen induction and overexpression of fibulin-1C mRNA in ovarian cancer cells. Oncogene 21, 1097-1107.
17. Plenefisch, J. D., Zhu, X. and Hedgecock, E. M. (2000). Fragile skeletal muscle attachments in dystrophic mutants of Caenorhabditis elegans: isolation and characterization of the mua genes. Development 127, 1197-1207.
18. Qing, J., Maher, V. M., Tran, H., Argraves, W. S., Dunstan, R. W. and McCormick, J. J. (1997). Suppression of anchorage-independent growth and matrigel invasion and delayed tumor formation by elevated expression of fibulin-1D in human fibrosarcoma-derived cell lines. Oncogene 15, 2159-2168.
19. Rogalski, T. M., Williams, B. D., Mullen, G. P. and Moerman, D. G. (1993). Products of the unc-52 gene in Caenorhabditis clegans are homologous to the core protein of the mammalian basement membrane heparan sulfate proteoglycan. Genes Dev. 7, 1471-1484.
20. Sasaki, T., Kostka, G., Gohring, W., Wiedemann, H., Mann, K., Chu, M. L. and Timpl, R. (1995). Structural characterization of two variants of fibulin-1 that differ in nidogen affinity. J. Mol. Biol. 245, 241-250.
21. Schultz, D. W., Klein, M. L., Humpert, A. J., Luzier, C. W., Persun, V., Schain, M., Mahan, A., Runckel, C., Cassera, M., Vittal, V. et al. (2003). Analysis of the ARMD1 locus: evidence that a mutation in Hemicentin-1 is associated with age-related macular degeneration in a large family. Human Mol. Genet. 12, 3315-3323.
22. Stone, E. M., Lotery, A. J., Munier, F. L., Heon, E., Piguet, B., Guymer, R. H., Vandenburgh, K., Cousin, P., Nishimura, D., Swiderski, R. E. et al. (1999). A single EFEMP1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy. Nat. Genet. 22, 199-202.
23. Stone, E. M., Braun, T. A., Russell, S. R., Kuehn, M. H., Lotery, A. J., Moore, P. A., Eastman, C. G., Casavant, T. L. and Sheffield, V. C. (2004). Missense variations in the fibulin 5 gene and age-related macular degeneration. New Engl. J. Med. 351, 346-353.
24. Timpl, R., Sasaki, T., Kostka, G. and Chu, M. L. (2003). Fibulins: a versatile family of extracellular matrix proteins. Nat. Rev. Mol. Cell Biol. 4, 479-489.
25. Toren, A., Rozenfeld-Granot, G., Heath, K. E., Amariglio, N., Rocca, B., Crosson, J., Epstein, C. J., Laghi, F., Landolfi, R., Carlsson, L. E. et al. (2003). MYH9 spectrum of autosomal-dominant giant platelet syndromes: Unexpected association with fibulin-1 variant-D inactivation. Am. J. Hematol. 74, 254-262.
26. Vogel, B. E. and Hedgecock, E. M. (2001). Hemicentin, a conserved extracellular member of the immunoglobulin superfamily, organizes epithelial and other cell attachments into oriented line-shaped junctions. Development 128, 883-894.