-
1
-
-
0026647857
-
Marine sponge polyketide inhibitors of protein tyrosine kinase
-
Lee RH, Slate DL, Moretti R, Alvi KA, Crews P (1992) Marine sponge polyketide inhibitors of protein tyrosine kinase. Biochem Biophys Res Commun 184:765-772
-
(1992)
Biochem Biophys Res Commun
, vol.184
, pp. 765-772
-
-
Lee, R.H.1
Slate, D.L.2
Moretti, R.3
Alvi, K.A.4
Crews, P.5
-
2
-
-
0001186572
-
Halenaquinone, a pentacyclic polyketide from a marine sponge
-
Roll DM, Scheuer PJ, Matsumoto GK, Clardy J (1983) Halenaquinone, a pentacyclic polyketide from a marine sponge. J Am Chem Soc 105:6177-6178
-
(1983)
J Am Chem Soc
, vol.105
, pp. 6177-6178
-
-
Roll, D.M.1
Scheuer, P.J.2
Matsumoto, G.K.3
Clardy, J.4
-
3
-
-
0023737162
-
Xesto- and halenaquinone derivatives from a sponge, Adocia sp., from truk lagoon
-
Schmitz FJ, Bloor SJ (1988) Xesto- and halenaquinone derivatives from a sponge, Adocia sp., from truk lagoon. J Org Chem 53:3922-3925
-
(1988)
J Org Chem
, vol.53
, pp. 3922-3925
-
-
Schmitz, F.J.1
Bloor, S.J.2
-
4
-
-
0035830639
-
Halenaquinone, a novel phosphatidylinositol 3-kinase inhibitor from a marine sponge, induces apoptosis in PC12 cells
-
Fujiwara H, Matsunaga K, Saito M et al (2001) Halenaquinone, a novel phosphatidylinositol 3-kinase inhibitor from a marine sponge, induces apoptosis in PC12 cells. Eur J Pharmacol 413:37-45
-
(2001)
Eur J Pharmacol
, vol.413
, pp. 37-45
-
-
Fujiwara, H.1
Matsunaga, K.2
Saito, M.3
-
5
-
-
8644255065
-
Synthesis of a new class of furan-fused tetracyclic compounds using o-quinodimethane chemistry and investigation of their antiviral activity.
-
Matsuya Y, Sasaki K, Nagaoka M et al (2004) Synthesis of a new class of furan-fused tetracyclic compounds using o-quinodimethane chemistry and investigation of their antiviral activity. J Org Chem 69:7989-7993
-
(2004)
J Org Chem
, vol.69
, pp. 7989-7993
-
-
Matsuya, Y.1
Sasaki, K.2
Nagaoka, M.3
-
6
-
-
0035113848
-
A randomized clinical trial of radiation therapy versus thermoradiotherapy in stage IIIB cervical carcinoma
-
Harima Y, Nagata K, Harima K, Ostapenko VV, Tanaka Y, Sawada S (2001) A randomized clinical trial of radiation therapy versus thermoradiotherapy in stage IIIB cervical carcinoma. Int J Hyperthermia 17:97-105
-
(2001)
Int J Hyperthermia
, vol.17
, pp. 97-105
-
-
Harima, Y.1
Nagata, K.2
Harima, K.3
Ostapenko, V.V.4
Tanaka, Y.5
Sawada, S.6
-
7
-
-
0028934336
-
Randomised trial of hyperthermia as adjuvant to radiotherapy for recurrent or metastatic malignant melanoma. European Society for Hyperthermic Oncology
-
Overgaard J, Gonzalez Gonzalez D, Hulshof MC et al (1995) Randomised trial of hyperthermia as adjuvant to radiotherapy for recurrent or metastatic malignant melanoma. European Society for Hyperthermic Oncology. Lancet 345:540-543
-
(1995)
Lancet
, vol.345
, pp. 540-543
-
-
Overgaard, J.1
Gonzalez, D.2
Hulshof, M.C.3
-
8
-
-
0342545492
-
Comparison of radiotherapy alone with radiotherapy plus hyperthermia in locally advanced pelvic tumours: A prospective, randomised, multicentre trial. Dutch Deep Hyperthermia Group
-
van der Zee J, Gonzalez Gonzalez D, van Rhoon GC, van Dijk JD, van Putten WL, Hart AA (2000) Comparison of radiotherapy alone with radiotherapy plus hyperthermia in locally advanced pelvic tumours: a prospective, randomised, multicentre trial. Dutch Deep Hyperthermia Group. Lancet 355:1119-1125
-
(2000)
Lancet
, vol.355
, pp. 1119-1125
-
-
Van Der Zee, J.1
Gonzalez, D.2
Van Rhoon, G.C.3
Van Dijk, J.D.4
Van Putten, W.L.5
Hart, A.A.6
-
9
-
-
0030200474
-
Radiotherapy with or without hyperthermia in the treatment of superficial localized breast cancer: Results from five randomized controlled trials. International Collaborative Hyperthermia Group
-
Vernon CC, Hand JW, Field SB et al (1996) Radiotherapy with or without hyperthermia in the treatment of superficial localized breast cancer: results from five randomized controlled trials. International Collaborative Hyperthermia Group. Int J Radiat Oncol Biol Phys 35:731-744
-
(1996)
Int J Radiat Oncol Biol Phys
, vol.35
, pp. 731-744
-
-
Vernon, C.C.1
Hand, J.W.2
Field, S.B.3
-
10
-
-
0032984266
-
For the clinical application of thermochemotherapy given at mild temperatures
-
Urano M, Kuroda M, Nishimura Y (1999) For the clinical application of thermochemotherapy given at mild temperatures. Int J Hyperthermia 15:79-107
-
(1999)
Int J Hyperthermia
, vol.15
, pp. 79-107
-
-
Urano, M.1
Kuroda, M.2
Nishimura, Y.3
-
11
-
-
0036150121
-
Referee: Hyperthermia alone or combined with cisplatin in addition to radiotherapy for advanced uterine cervical cancer
-
Dahl O, Mella O (2002) Referee: hyperthermia alone or combined with cisplatin in addition to radiotherapy for advanced uterine cervical cancer. Int J Hyperthermia 18:25-30
-
(2002)
Int J Hyperthermia
, vol.18
, pp. 25-30
-
-
Dahl, O.1
Mella, O.2
-
12
-
-
0036150198
-
Counterpoint: Test the value of hyperthermia in patients with carcinoma of the cervix being treated with concurrent chemotherapy and radiation
-
Prosnitz L, Jones E (2002) Counterpoint: test the value of hyperthermia in patients with carcinoma of the cervix being treated with concurrent chemotherapy and radiation. Int J Hyperthermia 18:13-18
-
(2002)
Int J Hyperthermia
, vol.18
, pp. 13-18
-
-
Prosnitz, L.1
Jones, E.2
-
13
-
-
0034220882
-
Radiation-induced apoptosis: Predictive and therapeutic significance in radiotherapy of prostate cancer (review)
-
Szostak MJ, Kyprianou N (2000) Radiation-induced apoptosis: predictive and therapeutic significance in radiotherapy of prostate cancer (review). Oncol Rep 7:699-706
-
(2000)
Oncol Rep
, vol.7
, pp. 699-706
-
-
Szostak, M.J.1
Kyprianou, N.2
-
14
-
-
0032696041
-
Reversal of radiation resistance in LNCaP cells by targeting apoptosis through ceramide synthase
-
Garzotto M, Haimovitz-Friedman A, Liao WC et al (1999) Reversal of radiation resistance in LNCaP cells by targeting apoptosis through ceramide synthase. Cancer Res 59:5194-5201
-
(1999)
Cancer Res
, vol.59
, pp. 5194-5201
-
-
Garzotto, M.1
Haimovitz-Friedman, A.2
Liao, W.C.3
-
15
-
-
0038407274
-
2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism
-
Lin X, Zhang F, Bradbury CM et al (2003) 2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism. Cancer Res 63:3413-3417
-
(2003)
Cancer Res
, vol.63
, pp. 3413-3417
-
-
Lin, X.1
Zhang, F.2
Bradbury, C.M.3
-
16
-
-
0942300643
-
Apoptosis-modulating agents in combination with radiotherapy-current status and outlook
-
Belka C, Jendrossek V, Pruschy M, Vink S, Verheij M, Budach W (2004) Apoptosis-modulating agents in combination with radiotherapy-current status and outlook. Int J Radiat Oncol Biol Phys 58:542-554
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.58
, pp. 542-554
-
-
Belka, C.1
Jendrossek, V.2
Pruschy, M.3
Vink, S.4
Verheij, M.5
Budach, W.6
-
17
-
-
0034785349
-
The benefits and hazards of antioxidants: Controlling apoptosis and other protective mechanisms in cancer patients and the human population
-
discussion 473S-475S
-
Salganik RI (2001) The benefits and hazards of antioxidants: controlling apoptosis and other protective mechanisms in cancer patients and the human population. J Am Coll Nutr 20:464S-472S; discussion 473S-475S
-
(2001)
J Am Coll Nutr
, vol.20
-
-
Salganik, R.I.1
-
20
-
-
0032541026
-
Increased flux of free radicals in cells subjected to hyperthermia: Detection by electron paramagnetic resonance spin trapping
-
Flanagan SW, Moseley PL, Buettner GR (1998) Increased flux of free radicals in cells subjected to hyperthermia: detection by electron paramagnetic resonance spin trapping. FEBS Lett 431:285-286
-
(1998)
FEBS Lett
, vol.431
, pp. 285-286
-
-
Flanagan, S.W.1
Moseley, P.L.2
Buettner, G.R.3
-
21
-
-
0032127346
-
Enhancement of oxidative cell injury and antitumor effects of localized 44 degrees C hyperthermia upon combination with respiratory hyperoxia and xanthine oxidase
-
Frank J, Kelleher DK, Pompella A, Thews O, Biesalski HK, Vaupel P (1998) Enhancement of oxidative cell injury and antitumor effects of localized 44 degrees C hyperthermia upon combination with respiratory hyperoxia and xanthine oxidase. Cancer Res 58:2693-2698
-
(1998)
Cancer Res
, vol.58
, pp. 2693-2698
-
-
Frank, J.1
Kelleher, D.K.2
Pompella, A.3
Thews, O.4
Biesalski, H.K.5
Vaupel, P.6
-
22
-
-
0027238868
-
The role of active oxygen species and lipid peroxidation in the antitumor effect of hyperthermia
-
Yoshikawa T, Kokura S, Tainaka K et al (1993) The role of active oxygen species and lipid peroxidation in the antitumor effect of hyperthermia. Cancer Res 53:2326-2329
-
(1993)
Cancer Res
, vol.53
, pp. 2326-2329
-
-
Yoshikawa, T.1
Kokura, S.2
Tainaka, K.3
-
23
-
-
0037166358
-
Enhancement of hyperthermia-induced apoptosis by local anesthetics on human histiocytic lymphoma U937 cells
-
Arai Y, Kondo T, Tanabe K et al (2002) Enhancement of hyperthermia-induced apoptosis by local anesthetics on human histiocytic lymphoma U937 cells. J Biol Chem 277:18986-18993
-
(2002)
J Biol Chem
, vol.277
, pp. 18986-18993
-
-
Arai, Y.1
Kondo, T.2
Tanabe, K.3
-
24
-
-
30344460689
-
Enhancement of apoptosis by nitric oxide released from alpha-phenyl-tert-butyl nitrone under hyperthermic conditions
-
Cui ZG, Kondo T, Matsumoto H (2006) Enhancement of apoptosis by nitric oxide released from alpha-phenyl-tert-butyl nitrone under hyperthermic conditions. J Cell Physiol 206:468-476
-
(2006)
J Cell Physiol
, vol.206
, pp. 468-476
-
-
Cui, Z.G.1
Kondo, T.2
Matsumoto, H.3
-
25
-
-
0034905658
-
Enhancement of hyperthermia-induced apoptosis by a free radical initiator, 2,2′-azobis (2-amidinopropane) dihydrochloride, in human histiocytic lymphoma U937 cells
-
Li FJ, Kondo T, Zhao QL et al (2001) Enhancement of hyperthermia-induced apoptosis by a free radical initiator, 2,2′-azobis (2-amidinopropane) dihydrochloride, in human histiocytic lymphoma U937 cells. Free Radic Res 35:281-299
-
(2001)
Free Radic Res
, vol.35
, pp. 281-299
-
-
Li, F.J.1
Kondo, T.2
Zhao, Q.L.3
-
26
-
-
0037613718
-
A free radical initiator, 2,2′-azobis (2-aminopropane) dihydrochloride enhances hyperthermia-induced apoptosis in human uterine cervical cancer cell lines
-
Yuki H, Kondo T, Zhao QL et al (2003) A free radical initiator, 2,2′-azobis (2-aminopropane) dihydrochloride enhances hyperthermia-induced apoptosis in human uterine cervical cancer cell lines. Free Radic Res 37:631-643
-
(2003)
Free Radic Res
, vol.37
, pp. 631-643
-
-
Yuki, H.1
Kondo, T.2
Zhao, Q.L.3
-
27
-
-
33644895407
-
Mechanism of cell death induction by nitroxide and hyperthermia
-
Zhao QL, Fujiwara Y, Kondo T (2006) Mechanism of cell death induction by nitroxide and hyperthermia. Free Radic Biol Med 40:1131-1143
-
(2006)
Free Radic Biol Med
, vol.40
, pp. 1131-1143
-
-
Zhao, Q.L.1
Fujiwara, Y.2
Kondo, T.3
-
28
-
-
20444475327
-
A hydrogen peroxide-generating agent, 6-formylpterin, enhances heat-induced apoptosis
-
Wada S, Cui ZG, Kondo T et al (2005) A hydrogen peroxide-generating agent, 6-formylpterin, enhances heat-induced apoptosis. Int J Hyperthermia 21:231-246
-
(2005)
Int J Hyperthermia
, vol.21
, pp. 231-246
-
-
Wada, S.1
Cui, Z.G.2
Kondo, T.3
-
29
-
-
1842431023
-
Enhancement of radiation-induced apoptosis by 6-formylpterin
-
Cui ZG, Kondo T, Ogawa R et al (2004) Enhancement of radiation-induced apoptosis by 6-formylpterin. Free Radic Res 38:363-373
-
(2004)
Free Radic Res
, vol.38
, pp. 363-373
-
-
Cui, Z.G.1
Kondo, T.2
Ogawa, R.3
-
30
-
-
0023612470
-
Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes
-
Sellins KS, Cohen JJ (1987) Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes. J Immunol 139:3199-3206
-
(1987)
J Immunol
, vol.139
, pp. 3199-3206
-
-
Sellins, K.S.1
Cohen, J.J.2
-
31
-
-
0029994562
-
Radiation-induced apoptosis in HL60 cells: Oxygen effect, relationship between apoptosis and loss of clonogenicity, and dependence of time to apoptosis on radiation dose
-
Hopcia KL, McCarey YL, Sylvester FC, Held KD (1996) Radiation-induced apoptosis in HL60 cells: oxygen effect, relationship between apoptosis and loss of clonogenicity, and dependence of time to apoptosis on radiation dose. Radiat Res 145:315-323
-
(1996)
Radiat Res
, vol.145
, pp. 315-323
-
-
Hopcia, K.L.1
McCarey, Y.L.2
Sylvester, F.C.3
Held, K.D.4
-
32
-
-
0032950961
-
Mitochondrial and intracellular free-calcium regulation of radiation-induced apoptosis in human leukemic cells
-
Zhao QL, Kondo T, Noda A, Fujiwara Y (1999) Mitochondrial and intracellular free-calcium regulation of radiation-induced apoptosis in human leukemic cells. Int J Radiat Biol 75:493-504
-
(1999)
Int J Radiat Biol
, vol.75
, pp. 493-504
-
-
Zhao, Q.L.1
Kondo, T.2
Noda, A.3
Fujiwara, Y.4
-
34
-
-
0030795091
-
Caspase-3-mediated cleavage of protein kinase C theta in induction of apoptosis
-
Datta R, Kojima H, Yoshida K, Kufe D (1997) Caspase-3-mediated cleavage of protein kinase C theta in induction of apoptosis. J Biol Chem 272:20317-20320
-
(1997)
J Biol Chem
, vol.272
, pp. 20317-20320
-
-
Datta, R.1
Kojima, H.2
Yoshida, K.3
Kufe, D.4
-
35
-
-
0031027794
-
Role of peroxide and superoxide anion during tumour cell apoptosis
-
Gorman A, McGowan A, Cotter TG (1997) Role of peroxide and superoxide anion during tumour cell apoptosis. FEBS Lett 404:27-33
-
(1997)
FEBS Lett
, vol.404
, pp. 27-33
-
-
Gorman, A.1
McGowan, A.2
Cotter, T.G.3
-
36
-
-
0027249757
-
Evaluation of 2′,7′-dichlorofluorescin and dihydrorhodamine 123 as fluorescent probes for intracellular H2O2 in cultured endothelial cells
-
Royall JA, Ischiropoulos H (1993) Evaluation of 2′,7′- dichlorofluorescin and dihydrorhodamine 123 as fluorescent probes for intracellular H2O2 in cultured endothelial cells. Arch Biochem Biophys 302:348-355
-
(1993)
Arch Biochem Biophys
, vol.302
, pp. 348-355
-
-
Royall, J.A.1
Ischiropoulos, H.2
-
37
-
-
0033971901
-
Bcl-2 family: Life-or-death switch
-
Tsujimoto Y, Shimizu S (2000) Bcl-2 family: life-or-death switch. FEBS Lett 466:6-10
-
(2000)
FEBS Lett
, vol.466
, pp. 6-10
-
-
Tsujimoto, Y.1
Shimizu, S.2
-
38
-
-
0034647691
-
Pivotal role of reactive oxygen species as intracellular mediators of hyperthermia-induced apoptosis
-
Katschinski DM, Boos K, Schindler SG, Fandrey J (2000) Pivotal role of reactive oxygen species as intracellular mediators of hyperthermia-induced apoptosis. J Biol Chem 275:21094-21098
-
(2000)
J Biol Chem
, vol.275
, pp. 21094-21098
-
-
Katschinski, D.M.1
Boos, K.2
Schindler, S.G.3
Fandrey, J.4
-
39
-
-
0023033269
-
Nitrogen metabolism and lipid peroxidation during hyperthermic perfusion of human livers with cancer
-
Skibba JL, Quebbeman EJ, Kalbfleisch JH (1986) Nitrogen metabolism and lipid peroxidation during hyperthermic perfusion of human livers with cancer. Cancer Res 46:6000-6003
-
(1986)
Cancer Res
, vol.46
, pp. 6000-6003
-
-
Skibba, J.L.1
Quebbeman, E.J.2
Kalbfleisch, J.H.3
-
40
-
-
0034616946
-
Apoptotic pathways: Paper wraps stone blunts scissors
-
Green DR (2000) Apoptotic pathways: paper wraps stone blunts scissors. Cell 102:1-4
-
(2000)
Cell
, vol.102
, pp. 1-4
-
-
Green, D.R.1
-
41
-
-
0035890085
-
The expanding role of mitochondria in apoptosis
-
Wang X (2001) The expanding role of mitochondria in apoptosis. Genes Dev 15:2922-2933
-
(2001)
Genes Dev
, vol.15
, pp. 2922-2933
-
-
Wang, X.1
-
42
-
-
0030925774
-
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
-
Medema JP, Scaffidi C, Kischkel FC et al (1997) FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). Embo J 16:2794-2804
-
(1997)
Embo J
, vol.16
, pp. 2794-2804
-
-
Medema, J.P.1
Scaffidi, C.2
Kischkel, F.C.3
-
43
-
-
0030892234
-
Apoptosis by death factor
-
Nagata S (1997) Apoptosis by death factor. Cell 88:355-365
-
(1997)
Cell
, vol.88
, pp. 355-365
-
-
Nagata, S.1
-
44
-
-
0030826338
-
FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b
-
Scaffidi C, Medema JP, Krammer PH, Peter ME (1997) FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b. J Biol Chem 272:26953-26958
-
(1997)
J Biol Chem
, vol.272
, pp. 26953-26958
-
-
Scaffidi, C.1
Medema, J.P.2
Krammer, P.H.3
Peter, M.E.4
-
45
-
-
0034785591
-
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
-
Suzuki Y, Imai Y, Nakayama H, Takahashi K, Takio K, Takahashi R (2001) A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Mol Cell 8:613-621
-
(2001)
Mol Cell
, vol.8
, pp. 613-621
-
-
Suzuki, Y.1
Imai, Y.2
Nakayama, H.3
Takahashi, K.4
Takio, K.5
Takahashi, R.6
-
46
-
-
0032575688
-
The Bcl-2 protein family: Arbiters of cell survival
-
Adams JM, Cory S (1998) The Bcl-2 protein family: arbiters of cell survival. Science 281:1322-1326
-
(1998)
Science
, vol.281
, pp. 1322-1326
-
-
Adams, J.M.1
Cory, S.2
-
47
-
-
0033879526
-
Bcl-2 does not inhibit cell death induced by the physiological Fas ligand: Implications for the existence of type I and type II cells
-
Huang DC, Tschopp J, Strasser A (2000) Bcl-2 does not inhibit cell death induced by the physiological Fas ligand: implications for the existence of type I and type II cells. Cell Death Differ 7:754-755
-
(2000)
Cell Death Differ
, vol.7
, pp. 754-755
-
-
Huang, D.C.1
Tschopp, J.2
Strasser, A.3
-
48
-
-
0033981577
-
Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane
-
Eskes R, Desagher S, Antonsson B, Martinou JC (2000) Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane. Mol Cell Biol 20:929-935
-
(2000)
Mol Cell Biol
, vol.20
, pp. 929-935
-
-
Eskes, R.1
Desagher, S.2
Antonsson, B.3
Martinou, J.C.4
-
49
-
-
0034663829
-
TBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c
-
Wei MC, Lindsten T, Mootha VK et al (2000) tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c. Genes Dev 14:2060-2071
-
(2000)
Genes Dev
, vol.14
, pp. 2060-2071
-
-
Wei, M.C.1
Lindsten, T.2
Mootha, V.K.3
-
50
-
-
0037216823
-
Reactive oxygen species regulate FLICE inhibitory protein (FLIP) and susceptibility to Fas-mediated apoptosis in cardiac myocytes
-
Nitobe J, Yamaguchi S, Okuyama M et al (2003) Reactive oxygen species regulate FLICE inhibitory protein (FLIP) and susceptibility to Fas-mediated apoptosis in cardiac myocytes. Cardiovasc Res 57:119-128
-
(2003)
Cardiovasc Res
, vol.57
, pp. 119-128
-
-
Nitobe, J.1
Yamaguchi, S.2
Okuyama, M.3
-
51
-
-
0032926670
-
FADD/MORT1, a signal transducer that can promote cell death or cell growth
-
Strasser A, Newton K (1999) FADD/MORT1, a signal transducer that can promote cell death or cell growth. Int J Biochem Cell Biol 31:533-537
-
(1999)
Int J Biochem Cell Biol
, vol.31
, pp. 533-537
-
-
Strasser, A.1
Newton, K.2
-
52
-
-
0034280579
-
Signal transduction mediated by Bid, a pro-death Bcl-2 family proteins, connects the death receptor and mitochondria apoptosis pathways
-
Yin XM (2000) Signal transduction mediated by Bid, a pro-death Bcl-2 family proteins, connects the death receptor and mitochondria apoptosis pathways. Cell Res 10:161-167
-
(2000)
Cell Res
, vol.10
, pp. 161-167
-
-
Yin, X.M.1
|