N-Acetyltransferase Mpr1 confers ethanol tolerance on Saccharomyces cerevisiae by reducing reactive oxygen species

Applied Microbiology and Biotechnology

Volumn 75, Issue 6, 2007, Pages 1343-1351

  Du, Xiaoyi ^a   Takagi, Hiroshi ^b  

^a FUKUI PREFECTURAL UNIVERSITY   (Japan)

^b NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

Ethanol tolerance; N Acetyltransferase Mpr1; Oxidative stress; Reactive oxygen species; Saccharomyces cerevisiae

Indexed keywords

ETHANOL TOLERANCE; N-ACETYLTRANSFERASE MPR1; REACTIVE OXYGEN SPECIES;

DETOXIFICATION; ENZYMES; ETHANOL; GENE ENCODING; OXIDATIVE STRESS;

YEAST;

ACYLTRANSFERASE; ALCOHOL; CATALASE A; CATALASE T; ENZYME; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTIOXIDANT; ENZYME; ETHANOL; GENE EXPRESSION; MUTATION; OXIDATION; OXYGEN; REDUCTION; TOLERANCE; YEAST;

ALCOHOL TOLERANCE; ARTICLE; BREEDING; CONTROLLED STUDY; CTA1 GENE; CTT1 GENE; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; GPX1 GENE; HEAT SHOCK; MPR1 GENE; MPR2 GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION; SACCHAROMYCES CEREVISIAE; STRESS; YEAST; YEAST CELL;

ACETYLTRANSFERASES; ANTI-INFECTIVE AGENTS, LOCAL; DRUG RESISTANCE; ETHANOL; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

SACCHAROMYCES CEREVISIAE;

EID: 34250792218     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-007-0940-x     Document Type: Article

References (42)

1. Aguilera A, Benitez T (1985) Role of mitochondria in ethanol tolerance of Saccharomyces cerevisiae. Arch Microbiol 142:389-392
2. Alexandre H, Rousseaux I, Charpentier C (1994) Relationship between ethanol tolerance, lipid composition and plasma membrane fluidity in Saccharomyces cerevisiae and Kloeckera apiculata. FEMS Microbiol Lett 124:17-22
3. Buttner S, Eisenberg T, Herker E, Carmona-Gutierrez D, Kroemer G, Madeo F (2006) Why yeast cells can undergo apoptosis: death in times of peace, love, and war. J Cell Biol 175:521-525
4. Casey GP, Ingledew WM (1986) Ethanol tolerance in yeasts. Crit Rev Microbiol 13:219-280
5. Charizanis C, Juhnke H, Krems B, Entian KD (1999) The mitochondrial cytochrome c peroxidase Ccp1 of Saccharomyces cerevisiae is involved in conveying an oxidative stress signal to the transcription factor Pos9 (Skn7). Mol Gen Genet 262:437-447
6. Chi Z, Arneborg N (1999) Relationship between lipid composition, frequency of ethanol-induced respiratory deficient mutants, and ethanol tolerance in Saccharomyces cerevisiae. J Appl Microbiol 86:1047-1052
7. Costa V, Amorim MA, Reis E, Quintanilha A, Moradas-Ferreira P (1997) Mitochondrial superoxide dismutase is essential for ethanol tolerance of Saccharomyces cerevisiae in the post-diauxic phase. Microbiol 143:1649-1656
8. Davidson JF, Whyte B, Bissinger PH, Schiestl RH (1996) Oxidative stress is involved in heat-induced cell death in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 93:5116-5121
9. Du X, Takagi H (2005) N-Acetyltransferase Mpr1 conferred freeze tolerance in Saccharomyces cerevisiae by reducing reactive oxygen species. J Biochem 138:391-397
10. Fowden L (1956) Azetidine-2-carboxylic acid: a new cyclic imino acid occurring in plants. Biochem J 64:323-332
11. Furukawa K, Kitano H, Mizoguchi H, Hara S (2004) Effect of cellular inositol content on ethanol tolerance of Saccharomyces cerevisiae in sake brewing. J Biosci Bioeng 98:107-113
12. Haliwell B, Gutteridge JM (1984) Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem J 219:1-14
13. He XJ, Fassler JS (2005) Identification of novel Yap1p and Skn7p binding sites involved in the oxidative stress response of Saccharomyces cerevisiae. Mol Microbiol 58:1454-1467
14. Huh WK, Falvo JV, Gerke LC, Carroll AS, Howson RW, Weissman JS, O'Shea EK (2003) Global analysis of protein localization in budding yeast. Nature 425:686-691
15. Ibeas JI, Jimenez J (1997) Mitochondrial DNA loss caused by ethanol in Saccharomyces flor yeasts. Appl Environ Microbiol 63:7-12
16. Inoue Y, Matsuda T, Sugiyama K, Izawa S, Kimura A (1999) Genetic analysis of glutathione peroxidase in oxidative stress response of Saccharomyces cerevisiae. J Biol Chem 274:27002-27009
17. Inoue T, Iefuji H, Fuji T, Soga H, Satoh K (2000) Cloning and characterization of a gene complementing the mutation of an ethanol-sensitive mutant of sake yeast. Biosci Biotechnol Biochem 64:229-236
18. Jabs T (1999) Reactive oxygen intermediates as mediators of programmed cell death in plants and animals. Biochem Pharmacol 57:231-245
19. W191F mutant strains of Saccharomyces cerevisiae indicates that cytochrome c peroxidase functions in oxidative-stress signaling. J Inorg Biochem 100:1996-2008
20. Kimura Y, Nakamori S, Takagi H (2002) Polymorphism of the MPR1 gene required for toxic proline analogue resistance in the Saccharomyces cerevisiae complex species. Yeast 19:1437-1445
21. Köhrer K, Domdey H (1991) Preparation of high molecular weight RNA. In: Guthrie C, Fink GR (eds) Methods enzymology, vol. 194. Academic, San Diego, pp 398-405
22. Kumar A, Agarwal S, Heyman JA, Matson S, Heidtman M, Piccirillo S, Umansky L, Drawid A, Jansen R, Liu Y, Cheung KH, Miller P, Gerstein M, Roeder GS, Snyder M (2002) Subcellular localization of the yeast proteome. Genes Dev 16:707-719
23. Lee SM, Park JW (1998) Thermosensitive phenotype of yeast mutant lacking thioredoxin peroxidase. Arch Biochem Biophys 359:99-106
24. Lee J, Godon C, Lagniel G, Spector D, Garin J, Labarre J, Toledano MB (1999) Yap1 and Skn7 control two specialized oxidative stress response regulons in yeast. J Biol Chem 274:16040-16046
25. ΔΔCt method. Methods 25:402-408
26. Manfredini V, Martins VD, Peralba Mdo CR, Benfato MS (2005) Adaptative response to enhanced basal oxidative damage in sod mutants from Saccharomyces cerevisiae. Mol Cell Biochem 276:175-181
27. Mansure JJC, Panek AD, Crowe LM, Crowe JH (1994) Trehalose inhibits ethanol effects on intact yeast cells and liposomes. Biochim Biophys Acta 1191:309-316
28. Mishra P, Prasad R (1988) Role of phospholipid head groups in ethanol tolerance of Saccharomyces cerevisiae. J Gen Microbiol 134:3205-3211
29. Nestelbacher R, Laun P, Vondrakova D, Pichova A, Schuller C, Breitenbach M (2000) The influence of oxygen toxicity on yeast mother cell-specific aging. Exp Gerontol 35:63-70
30. Nomura M, Takagi H (2004) Role of the yeast novel acetyltransferase Mpr1 in oxidative stress: regulation of oxygen reactive species caused by a toxic proline catabolism intermediate. Proc Natl Acad Sci USA 101:12616-12621
31. Nomura M, Nakamori S, Takagi H (2003) Characterization of novel acetyltransferases found in the budding and fission yeasts that detoxifies a proline analogue, azetidine-2-carboxylic acid. J Biochem 133:67-74
32. O'Brien KM, Dirmeier R, Engle M, Poyton RO (2004) Mitochondrial protein oxidation in yeast mutants lacking manganese-(MnSOD) or copper- and zinc-containing superoxide dismutase (CuZnSOD): evidence that MnSOD and CuZnSOD have both unique and overlapping functions in protecting mitochondrial proteins from oxidative damage. J Biol Chem 279:51817-51827
33. Park JI, Grant CM, Attfield PA, Dawes IW (1997) The freeze-thaw stress response of the yeast Saccharomyces cerevisiae is growth phase specific and is controlled by nutritional state via the RAS-cyclic AMP signal transduction pathway. Appl Environ Microbiol 63:3818-3824
34. Peterson PJ, Fowden L (1963) Different specificities of proline-activating enzymes from some plant species. Nature 200:148-151
35. Piper PW (1995) The heat shock and ethanol stress responses of yeast exhibit extensive similarity and functional overlap. FEMS Microbiol Lett 134:121-127
36. 2 in cultured endothelial cells. Arch Biochem Biophys 302:348-355
37. Shichiri M, Hoshikawa C, Nakamori S, Takagi H (2001) A novel acetyltranferase found in Saccharomyces cerevisiae ∑1278b that detoxifies a proline analogue, azetidine-2-carboxylic acid. J Biol Chem 276:41998-42002
38. Susani M, Zimniak P, Fessl F, Ruis H (1976) Localization of catalase A in vacuoles of Saccharomyces cerevisiae: evidence for the vacuolar nature of isolated "yeast peroxisomes". Hoppe-Seyler Z Physiol Chem 357:961-970
39. Takagi H, Shichiri M, Takemura M, Mohri M, Nakamori S (2000) Saccharomyces cerevisiae ∑1278b has novel gene of the N-acetyltransferase gene superfamily required for l-proline analogue resistance. J Bacteriol 182:4249-4256
40. Takagi H, Takaoka M, Kawaguchi A, Kubo Y (2005) Effect of l-proline on sake brewing and ethanol stress in Saccharomyces cerevisiae. Appl Environ Microbiol 71:8656-8662
41. Tsuchiya M, Suematsu M, Suzuki H (1994) In vivo visualization of oxygen radical-dependent photoemission. Methods Enzymol 233:128-140
42. Wong CM, Zhou Y, Ng RW, Kung HF, Jin DY (2002) Cooperation of yeast peroxiredoxins Tsa1p and Tsa2p in the cellular defense against oxidative and nitrosative stress. J Biol Chem 277:5385-5394