Drug effects on the mechanical properties of large arteries in humans

Clinical and Experimental Pharmacology and Physiology

Volumn 34, Issue 7, 2007, Pages 688-693

  Hope, Sarah A ^a   Hughes, Alun D ^b  

^a MONASH MEDICAL CENTRE   (Australia)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Arterial stiffness; Augmentation index; Blood pressure; Drugs; Pulse wave velocity

Indexed keywords

ALAGEBRIUM; ALPHA TOCOPHEROL; AMLODIPINE; ANGIOTENSIN II; ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; METFORMIN; NITRATE; PERINDOPRIL; SILDENAFIL; SPIRONOLACTONE; SULFONYLUREA; THIAZIDE DIURETIC AGENT; THIOCTIC ACID;

BLOOD PRESSURE REGULATION; CARDIOVASCULAR DISEASE; DRUG EFFECT; DRUG EFFICACY; HUMAN; PROPHYLAXIS; PULSE WAVE; REVIEW; WAVEFORM;

ARTERIES; BIOMECHANICS; BLOOD PRESSURE; CARDIOVASCULAR AGENTS; CARDIOVASCULAR DISEASES; CLINICAL TRIALS; COMPLIANCE; DRUG EVALUATION, PRECLINICAL; HUMANS; PULSATILE FLOW; RESEARCH DESIGN;

EID: 34250753190     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2007.04661.x     Document Type: Review

References (89)

1. Nichols WW, O'Rourke MF. McDonald's Blood Flow in Arteries, 5th edn. Edward Arnold, London. 2005.
2. Laurent S, Boutouyrie P, Lacolley P. Structural and genetic bases of arterial stiffness. Hypertension 2005 45 : 1050 5.
3. Vaitkevicius PV, Lane M, Spurgeon H et al. A cross-link breaker has sustained effects on arterial and ventricular properties in older rhesus monkeys. Proc. Natl Acad. Sci. USA 2001 98 : 1171 5.
4. Vito RP, Dixon SA. Blood vessel constitutive models: 1995-2002. Annu. Rev. Biomed. Eng. 2003 5 : 413 39.
5. Cameron J. Estimation of arterial mechanics in clinical practice and as a research technique. Clin. Exp. Pharmacol. Physiol. 1999 26 : 285 94.
6. Reneman RS, Meinders JM, Hoeks AP. Non-invasive ultrasound in arterial wall dynamics in humans: What have we learned and what remains to be solved. Eur. Heart J. 2005 26 : 960 6.
7. Oliver JJ, Webb DJ. Noninvasive assessment of arterial stiffness and risk of atherosclerotic events. Arterioscler. Thromb. Vasc. Biol. 2003 23 : 554 66.
8. Van Bortel LM, Duprez D, Starmans-Kool MJ et al. Clinical applications of arterial stiffness, Task Force III. Recommendations for user procedures. Am. J. Hypertens. 2002 15 : 445 52.
9. Young T. The Croonian lecture on the functions of the heart and arteries. Philos. Trans. R. Soc. Lond. 1809 24 : 1 31.
10. Mitchell GF, Lacourciere Y, Arnold JM, Dunlap ME, Conlin PR, Izzo Jr. JL. Changes in aortic stiffness and augmentation index after acute converting enzyme or vasopeptidase inhibition. Hypertension 2005 46 : 1111 17.
11. Topouchian J, Brisac AM, Pannier B, Vicaut E, Safar M, Asmar R. Assessment of the acute arterial effects of converting enzyme inhibition in essential hypertension: A double-blind, comparative and crossover study. J. Hum. Hypertens. 1998 12 : 181 7.
12. Hirata K, Vlachopoulos C, Adji A, O'Rourke MF. Benefits from angiotensin-converting enzyme inhibitor 'beyond blood pressure lowering': Beyond blood pressure or beyond the brachial artery? J. Hypertens. 2005 23 : 551 6.
13. Kelly RP, Millasseau SC, Ritter JM, Chowienczyk PJ. Vasoactive drugs influence aortic augmentation index independently of pulse-wave velocity in healthy men. Hypertension 2001 37 : 1429 33.
14. Vlachopoulos C, Hirata K, O'Rourke MF. Effect of caffeine on aortic elastic properties and wave reflection. J. Hypertens. 2003 21 : 563 70.
15. Pannier BM, Guerin AP, Marchais SJ, London GM. Different aortic reflection wave responses following long-term angiotensin-converting enzyme inhibition and beta-blocker in essential hypertension. Clin. Exp. Pharmacol. Physiol. 2001 28 : 1074 7.
16. Asmar RG, London GM, O'Rourke ME, Safar ME. Improvement in blood pressure, arterial stiffness and wave reflections with a very-low-dose perindopril/indapamide combination in hypertensive patient: A comparison with atenolol. Hypertension 2001 38 : 922 6.
17. Liang YL, Gatzka CD, Du XJ, Cameron JD, Kingwell BA, Dart AM. Effects of heart rate on arterial compliance in men. Clin. Exp. Pharmacol. Physiol. 1999 26 : 342 6.
18. Albaladejo P, Laurent P, Pannier B, Achimastos A, Safar M, Benetos A. Influence of sex on the relation between heart rate and aortic stiffness. J. Hypertens. 2003 21 : 555 62.
19. Karamanoglu M, Feneley MP. Late systolic pressure augmentation: Role of left ventricular outflow patterns. Am. J. Physiol. 1999 277 : H481 7.
20. Nichols WW. Clinical measurement of arterial stiffness obtained from noninvasive pressure waveforms. Am. J. Hypertens. 2005 18 (Suppl. 1 S3 10.
21. Chen CH, Nevo E, Fetics B et al. Estimation of central aortic pressure waveform by mathematical transformation of radial tonometry pressure. Validation of generalized transfer function. Circulation 1997 95 : 1827 36.
22. Fetics B, Nevo E, Chen CH, Kass DA. Parametric model derivation of transfer function for noninvasive estimation of aortic pressure by radial tonometry. IEEE Trans. Biomed. Eng. 1999 46 : 698 706.
23. McGrath BP, Liang YL, Kotsopoulos D, Cameron JD. Impact of physical and physiological factors on arterial function. Clin. Exp. Pharmacol. Physiol. 2001 28 : 1104 7.
24. Wilkinson IB, MacCallum H, Flint L, Cockcroft JR, Newby DE, Webb DJ. The influence of heart rate on augmentation index and central arterial pressure in humans. J. Physiol. 2000 525 : 263 70.
25. Dart AM, Reid CM, McGrath B. Effects of ACE inhibitor therapy on derived central arterial waveforms in hypertension. Am. J. Hypertens. 2001 14 : 804 10.
26. Dart AM, Reid CM, McGrath B. Effects of ACE inhibitor therapy on derived central arterial waveforms in hypertension. Am. J. Hypertens. 2001 15 : 477.
27. Karamanoglu M, O'Rourke MF, Avolio AP, Kelly RP. An analysis of the relationship between central aortic and peripheral upper limb pressure waves in man. Eur. Heart J. 1993 14 : 160 7.
28. Hope SA, Tay DB, Meredith IT, Cameron JD. Comparison of generalized and gender-specific transfer functions for the derivation of aortic waveforms. Am. J. Physiol. Heart Circ. Physiol. 2002 283 : H1150 6.
29. Hope SA, Tay DB, Meredith IT, Cameron JD. Use of arterial transfer functions for the derivation of aortic waveform characteristics. J. Hypertens. 2003 21 : 1299 305.
30. McLeod AL, Uren NG, Wilkinson IB et al. Non-invasive measures of pulse wave velocity correlate with coronary arterial plaque load in humans. J. Hypertens. 2004 22 : 363 8.
31. Pauca AL, O'Rourke MF, Kon ND. Prospective evaluation of a method for estimating ascending aortic pressure from the radial artery pressure waveform. Hypertension 2001 38 : 932 7.
32. Hope SA, Meredith IT, Cameron JD. Effect of non-invasive calibration of radial waveforms on error in transfer-function-derived central aortic waveform characteristics. Clin. Sci. 2004 107 : 205 11.
33. Soderstrom S, Nyberg G, O'Rourke MF, Sellgren J, Ponten J. Can a clinically useful aortic pressure wave be derived from a radial pressure wave? Br. J. Anaesth. 2002 88 : 481 8.
34. Segers P, Rietzschel E, Heireman S et al. Carotid tonometry versus synthesized aorta pressure waves for the estimation of central systolic blood pressure and augmentation index. Am. J. Hypertens. 2005 18 : 1168 73.
35. O'Rourke M, Pauca A, Kon N. Generation of ascending aortic from radial artery pressure waveform. J. Am. Coll. Cardiol. 2002 39 (Suppl. B 177 (Abstract).
36. Millasseau SC, Patel SJ, Redwood SR, Ritter JM, Chowienczyk PJ. Pressure wave reflection assessed from the peripheral pulse: Is a transfer function necessary? Hypertension 2003 41 : 1016 20.
37. Westerhof N, Sipkema P, van den Bos GC, Elzinga G. Forward and backward waves in the arterial system. Cardiovasc. Res. 1972 6 : 648 56.
38. Pythoud F, Stergiopulos N, Meister JJ. Separation of arterial pressure waves into their forward and backward running components. J. Biomech. Eng. 1996 118 : 295 301.
39. Khir AW, O'Brien A, Gibbs JS, Parker KH. Determination of wave speed and wave separation in the arteries. J. Biomech. 2001 34 : 1145 55.
40. Zambanini A, Cunningham SL, Parker KH, Khir AW, Thom SAMcG, Hughes AD. Wave-energy patterns in carotid, brachial, and radial arteries: A noninvasive approach using wave-intensity analysis. Am. J. Physiol. Heart Circ. Physiol. 2005 289 : H270 6.
41. Ohte N, Narita H, Sugawara M et al. Clinical usefulness of carotid arterial wave intensity in assessing left ventricular systolic and early diastolic performance. Heart Vessels 2003 18 : 107 11.
42. Niki K, Sugawara M, Uchida K et al. A noninvasive method of measuring wave intensity, a new hemodynamic index: Application to the carotid artery in patients with mitral regurgitation before and after surgery. Heart Vessels 1999 14 : 263 71.
43. Williams B, Lacy PS, Thom SM et al. Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: Principal results of the Conduit Artery Function Evaluation (CAFE) study. Circulation 2006 113 : 1213 25.
44. Dahlof B, Sever PS, Poulter NR et al. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): A multicentre randomised controlled trial. Lancet 2005 366 : 895 906.
45. Stergiopulos N, Segers P, Westerhof N. Use of pulse pressure method for estimating total arterial compliance in vivo. Am. J. Physiol. 1999 276 : H424 8.
46. Laskey WK, Parker HG, Ferrari VA, Kussmaul WG, Noordergraaf A. Estimation of total systemic arterial compliance in humans. J. Appl. Physiol. 1990 69 : 112 19.
47. Ahimastos AA, Natoli AK, Lawler A, Blombery PA, Kingwell BA. Ramipril reduces large-artery stiffness in peripheral arterial disease and promotes elastogenic remodeling in cell culture. Hypertension 2005 45 : 1194 9.
48. London GM, Pannier B, Vicaut E et al. Antihypertensive effects and arterial haemodynamic alterations during angiotensin converting enzyme inhibition. J. Hypertens. 1996 14 : 1139 46.
49. Asmar RG, Benetos A, Darne BM, Pauly NC, Safar ME. Converting enzyme inhibition: Dissociation between antihypertensive and arterial effects. J. Hum. Hypertens. 1992 6 : 381 5.
50. Asmar RG, Pannier B, Santoni JP et al. Reversion of cardiac hypertrophy and reduced arterial compliance after converting enzyme inhibition in essential hypertension. Circulation 1988 78 : 941 50.
51. Ting CT, Chen CH, Chang MS, Yin FC. Short- and long-term effects of antihypertensive drugs on arterial reflections, compliance, and impedance. Hypertension 1995 26 : 524 30.
52. Stokes GS, Barin ES, Gilfillan KL. Effects of isosorbide mononitrate and AII inhibition on pulse wave reflection in hypertension. Hypertension 2003 41 : 297 301.
53. Sharman JE, Gunaruwan P, Knez WL et al. Alpha-lipoic acid does not acutely affect resistance and conduit artery function or oxidative stress in healthy men. Br. J. Clin. Pharmacol. 2004 58 : 243 8.
54. Kass DA, Shapiro EP, Kawaguchi M et al. Improved arterial compliance by a novel advanced glycation end-product crosslink breaker. Circulation 2001 104 : 1464 70.
55. Suzuki H, Nakamoto H, Okada H, Sugahara S, Kanno Y. A selective angiotensin receptor antagonist, valsartan, produced regression of left ventricular hypertrophy associated with a reduction of arterial stiffness. Adv. Perit. Dial. 2003 19 : 59 66.
56. Klemsdal TO, Moan A, Kjeldsen SE. Effects of selective angiotensin II type 1 receptor blockade with losartan on arterial compliance in patients with mild essential hypertension. Blood Press. 1999 8 : 214 19.
57. Klingbeil AU, John S, Schneider MP, Jacobi J, Weidinger G, Schmieder RE. AT1-receptor blockade improves augmentation index: A double-blind, randomized, controlled study. J. Hypertens. 2002 20 : 2423 8.
58. Mitchell GF, Arnold JM, Dunlap ME et al. Pulsatile hemodynamic effects of candesartan in patients with chronic heart failure: The CHARM Program. Eur. J. Heart Fail. 2006 8 : 191 7.
59. Garg JP, Ellis R, Elliott WJ et al. Angiotensin receptor blockade and arterial compliance in chronic kidney disease: A pilot study. Am. J. Nephrol. 2005 25 : 393 9.
60. Lemogoum D, Van Bortel L, Van den Abeele W et al. Effect of beta-adrenergic stimulation on pulse wave velocity in black and white subjects. J. Hypertens. 2004 22 : 2349 53.
61. Wilkinson IB, Hall IR, MacCallum H et al. Pulse-wave analysis: Clinical evaluation of a noninvasive, widely applicable method for assessing endothelial function. Arterioscler. Thromb. Vasc. Biol. 2002 22 : 147 52.
62. Kelly R, Daley J, Avolio A, O'Rourke M. Arterial dilation and reduced wave reflection. Benefit of dilevalol in hypertension. Hypertension 1989 14 : 14 21.
63. Asmar RG, Kerihuel JC, Girerd XJ, Safar ME. Effect of bisoprolol on blood pressure and arterial hemodynamics in systemic hypertension. Am. J. Cardiol. 1991 68 : 61 4.
64. Asmar R, Benetos A, Brahimi M, Chaouche K, Safar M. Arterial and antihypertensive effects of nitrendipine: A double-blind comparison versus placebo. J. Cardiovasc. Pharmacol. 1992 20 : 858 63.
65. Pannier BM, Lafleche AB, Girerd XJ, London GM, Safar ME. Arterial stiffness and wave reflections following acute calcium blockade in essential hypertension. Am. J. Hypertens. 1994 7 : 168 76.
66. Stakos DA, Schuster DP, Sparks EA, Wooley CF, Osei K, Boudoulas H. Long term cardiovascular effects of oral antidiabetic agents in non-diabetic patients with insulin resistance: Double blind, prospective, randomised study. Heart 2005 91 : 589 94.
67. Laurent S, Arcaro G, Benetos A, Lafleche A, Hoeks A, Safar M. Mechanism of nitrate-induced improvement on arterial compliance depends on vascular territory. J. Cardiovasc. Pharmacol. 1992 19 : 641 9.
68. Wilkinson IB, MacCallum H, Cockcroft JR, Webb DJ. Inhibition of basal nitric oxide synthesis increases aortic augmentation index and pulse wave velocity in vivo. Br. J. Clin. Pharmacol. 2002 53 : 189 92.
69. Vlachopoulos C, Dima I, Aznaouridis K et al. Acute systemic inflammation increases arterial stiffness and decreases wave reflections in healthy individuals. Circulation 2005 112 : 2193 200.
70. Hirata K, Adji A, Vlachopoulos C, O'Rourke MF. Effect of sildenafil on cardiac performance in patients with heart failure. Am. J. Cardiol. 2005 96 : 1436 40.
71. Vlachopoulos C, Hirata K, O'Rourke MF. Effect of sildenafil on arterial stiffness and wave reflection. Vasc. Med. 2003 8 : 243 8.
72. Davies J, Gavin A, Band M, Morris A, Struthers A. Spironolactone reduces brachial pulse wave velocity and PIIINP levels in hypertensive diabetic patients. Br. J. Clin. Pharmacol. 2005 59 : 520 3.
73. Ichihara A, Hayashi M, Ryuzaki M, Handa M, Furukawa T, Saruta T. Fluvastatin prevents development of arterial stiffness in haemodialysis patients with type 2 diabetes mellitus. Nephrol. Dial. Transplant. 2002 17 : 1513 17.
74. Shige H, Dart A, Nestel P. Simvastatin improves arterial compliance in the lower limb but not in the aorta. Atherosclerosis 2001 155 : 245 50.
75. Raison J, Rudnichi A, Safar ME. Effects of atorvastatin on aortic pulse wave velocity in patients with hypertension and hypercholesterolaemia: A preliminary study. J. Hum. Hypertens. 2002 16 : 705 10.
76. Ferrier KE, Muhlmann MH, Baguet JP et al. Intensive cholesterol reduction lowers blood pressure and large artery stiffness in isolated systolic hypertension. J. Am. Coll. Cardiol. 2002 39 : 1020 5.
77. Vanmolkot FH, de Hoon JN. Acute effects of sumatriptan on aortic blood pressure, stiffness, and pressure waveform. Clin. Pharmacol. Ther. 2006 80 : 85 94.
78. Stakos DA, Schuster DP, Sparks EA, Wooley CF, Osei K, Boudoulas H. Long-term cardiovascular effects of insulin sensitizer troglitazone on non-diabetic individuals with insulin resistance: Double blind, prospective randomized study. J. Cardiol. 2003 41 : 183 90.
79. Mahmud A, Feely J. Divergent effect of acute and chronic alcohol on arterial stiffness. Am. J. Hypertens. 2002 15 : 240 3.
80. Turner B, Molgaard C, Marckmann P. Effect of garlic (Allium sativum) powder tablets on serum lipids, blood pressure and arterial stiffness in normo-lipidaemic volunteers: A randomised, double-blind, placebo-controlled trial. Br. J. Nutr. 2004 92 : 701 6.
81. Vlachopoulos C, Hirata K, O'Rourke MF. Pressure-altering agents affect central aortic pressures more than is apparent from upper limb measurements in hypertensive patients: The role of arterial wave reflections. Hypertension 2001 38 : 1456 60.
82. Waring WS, Goudsmit J, Marwick J, Webb DJ, Maxwell SR. Acute caffeine intake influences central more than peripheral blood pressure in young adults. Am. J. Hypertens. 2003 16 : 919 24.
83. Mangoni AA, Sherwood RA, Swift CG, Jackson SH. Folic acid enhances endothelial function and reduces blood pressure in smokers: A randomized controlled trial. J. Intern. Med. 2002 252 : 497 503.
84. Williams C, Kingwell BA, Burke K, McPherson J, Dart AM. Folic acid supplementation for 3 wk reduces pulse pressure and large artery stiffness independent of MTHFR genotype. Am. J. Clin. Nutr. 2005 82 : 26 31.
85. Teede HJ, McGrath BP, DeSilva L, Cehun M, Fassoulakis A, Nestel PJ. Isoflavones reduce arterial stiffness: A placebo-controlled study in men and postmenopausal women. Arterioscler. Thromb. Vasc. Biol. 2003 23 : 1066 71.
86. Nestel PJ, Yamashita T, Sasahara T et al. Soy isoflavones improve systemic arterial compliance but not plasma lipids in menopausal and perimenopausal women. Arterioscler. Thromb. Vasc. Biol. 1997 17 : 3392 8.
87. Zureik M, Galan P, Bertrais S et al. Effects of long-term daily low-dose supplementation with antioxidant vitamins and minerals on structure and function of large arteries. Arterioscler. Thromb. Vasc. Biol. 2004 24 : 1485 91.
88. Teede HJ, Dalais FS, Kotsopoulos D, Liang YL, Davis S, McGrath BP. Dietary soy has both beneficial and potentially adverse cardiovascular effects: A placebo-controlled study in men and postmenopausal women. J. Clin. Endocrinol. Metab. 2001 86 : 3053 60.
89. Rasool AH, Rehman A, Wan Yusuf WN, Rahman AR. Vitamin E and its effect on arterial stiffness in postmenopausal women: A randomized controlled trial. Int. J. Clin. Pharmacol. Ther. 2003 41 : 587 92.