AT1-receptor blockade improves augmentation index: A double-blind, randomized, controlled study

Journal of Hypertension

Volumn 20, Issue 12, 2002, Pages 2423-2428

  Klingbeil, Arnfried U ^a   John, Stefan ^a   Schneider, Markus P ^a   Jacobi, Johannes ^a   Weidinger, Gottfried ^a   Schmieder, Roland E ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Antihypertensive therapy; Augmentation index; Hypertension; Vasculature

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; HYDROCHLOROTHIAZIDE; VALSARTAN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN RECEPTOR; ANTIHYPERTENSIVE AGENT; DIURETIC AGENT; DRUG DERIVATIVE; TETRAZOLE DERIVATIVE; THIAZIDE DIURETIC AGENT; VALINE;

ADAPTATION; ADULT; ARTERIAL PRESSURE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ESSENTIAL HYPERTENSION; FEMALE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECEPTOR BLOCKING; SCORING SYSTEM; STATISTICAL ANALYSIS; SUPINE POSITION; AGED; AORTA; BLOOD PRESSURE; DIASTOLE; DRUG ANTAGONISM; DRUG EFFECT; MIDDLE AGED; PATHOPHYSIOLOGY; PULSE RATE; RADIAL ARTERY; SYSTOLE;

ADULT; AGED; ANTIHYPERTENSIVE AGENTS; AORTA; BLOOD PRESSURE; DIASTOLE; DIURETICS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; HYDROCHLOROTHIAZIDE; HYPERTENSION; MALE; MIDDLE AGED; PULSE; RADIAL ARTERY; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, ANGIOTENSIN; SODIUM CHLORIDE SYMPORTER INHIBITORS; SYSTOLE; TETRAZOLES; VALINE;

EID: 0036915333     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-200212000-00022     Document Type: Article

References (43)

1. Frohlich ED, Apstein C, Chobanian AV, Devereux RB, Dunstan HP, Dzau V, et al. The heart in hypertension. N Engl J Med 1992; 327:998-1008.
2. O'Rourke MF, Kelly RP. Wave reflection in the systemic circulation and its implications in ventricular function. J Hypertens 1993; 11:327-337.
3. O'Rourke MF, Cartmill TB. Influence of aortic coarctation on pulsatile hemodynamics in the proximal aorta. Circulation 1971; 44:281-292.
4. McVeigh GE, Brennan G, Hayes R, Cohn JN, Finkelstein S, Johnston D. Vascular abnormalities in non-insulin dependent diabetes mellitus identified by arterial waveform analysis. Am J Med 1993; 95:424-430.
5. Belz GG. Elastic properties and windkessel function of the human aorta. Cardiovasc Drugs Ther 1995; 9:73-83.
6. Smulyan H, Vardan S, Griffiths A, Gribbin B. Forearm arterial distensibility in systolic hypertension. J Am Coll Cardiol 1984; 3:3387-3393.
7. Kelly R, Haywood C, Avolio A, O'Rourke M. Noninvasive determination of age-related changes in the human arterial pulse. Circulation 1989; 80:1652-1659.
8. Kelly R, Fitchett D. Nonivasive determination of aortic input impedance and external left ventricular power output: A validation and reproducibility study of a new technique. J Am Coll Cardiol 1992; 20:952-963.
9. Dart A, Silagy C, Dewar E, Jennings G, McNeil J. Aortic distensibility and left ventricular structure and function in isolated systolic hypertension. Eur Heart J 1993; 14:1465-1470.
10. Saba PS, Maioli M, Petretto L, Pacifico A, Fadda R, Sanna GL, et al. Early abnormalities of pressure wave reflection in familial hypercholesterolemic subjects. J Hum Hypertens 2000; 14:279.
11. Wilkinson IB, MacCallum H, Rooijmans DF, Murray GD, Cockcroft JR, McKnight JA, et al. Increased augmentation index and systolic stress in type 1 diabetes mellitus. Quarterly J Med 2000; 93:441-448.
12. MacCallum H, Wilkinson IB, Thomas A, Van der Steen M, Frenneaux MP, Webb DJ, et al. Increased arterial stiffness as assessed by pulse wave analysis in patients with hypercholesterolaemia. J Hum Hypertens 2000; 14:280.
13. Safar ME, Toto-Moukouo JJ, Bouthier JA, Asmar RG, Levenson JA, Simon AC, et al. Arterial dynamics, cardiac hypertrophy, and antihypertensive treatment. Circulation 1987; 75(Suppl I): I-156-I-161.
14. Saba PS, Roman MJ, Pini R, Spitzer M, Ganau A, Devereux R. Relation of arterial pressure waveform to left ventricular and carotid anatomy in normotensive subjects. J Am Coll Cardiol 1993; 22:1873-1880.
15. Iketani T, Iketani Y, Takazawa K, Yamashina A. The influence of the peripheral reflection wave on left ventricular hypertrophy in patients with essential hypertension. Hypertens Res 2000; 23:451-458.
16. Rietzschel ER, DeBuyzere ML, Duprez DD, Clement DL. Multiregional intima-media thickness and non-invasively determined central haemodynamics. Circulation 2000; 102(Suppl II): II-608.
17. Chen CH, Ting CT, Lin SJ, Hsu TL, Yin FC, Siu CO, et al. Different effects of fosinopril and atenolol on wave reflections in hypertensive patients. Hypertension 1995; 25:1034-1041.
18. London GM, Pannier B, Vicaut E, Guerin AP, Marchais SJ, Safar ME, et al. Antihypertensive effects and arterial haemodynamic alterations during angiotensin converting enzyme inhibition. J Hypertens 1996; 14:1139-1146.
19. Simon AC, Levenson J, Bouthier JA, Safar M. Effects of chronic administration of enalapril and propranolol on the large arteries in essential hypertension. J Cardiovasc Pharmacol 1985; 7:856-861.
20. Kelly R, Daley J, Avolio A, O'Rourke M. Arterial dilation and reduced wave reflection. Benefit of dilevalol in hypertension. Hypertension 1989; 14:14-21.
21. Mahmud A, Feely J. Favourable effects on arterial wave reflection and pulse pressure amplification of adding angiotensin II receptor blockade in resistant hypertension. J Hum Hypertens 2000; 14:541-546.
22. The SphygmoCor™ Blood Pressure Analysis System. Version 3.1 Operators Manual. Sydney, Australia: PWV Medical; 1995.
23. Karamanoglou M, O'Rourke MK, Avolio AP, Kelly RP. An analysis of the relationship between central aortic and peripheral upper limb pressure waves in man. Eur Heart J 1993; 14:160-167.
24. Cameron JD, McGrath BP, Dart AM. Use of radial applanation tonometry and a generalized transfer function to determine aortic pressure augmentation in subjects with treated hypertension. J Am Col Cardiol 1998; 32:1214-1220.
25. Wilkinson IB, MacCallum H, Flint L, Cockcroft JR, Newby DE, Webb DJ. The influence of heart rate on augmentation index and central arterial pressure in humans. J Physiol 2000; 525:263-270.
26. Chen C-H, Ting C-T, Nussbacher A, Nevo E, Kass DA, Pak P, et al. Validation of carotid artery tonometry as a means of estimating augmentation index of ascending aortic pressure. Hypertension 1996; 27:168-175.
27. O'Rourke MF. Influence of ventricular ejection on the relationship between central aortic and brachial pressure pulse in man. Cardiovasc Res 1970; 4:291-300.
28. Lasance HAJ, Wesseling KH, Asdoop CA. Peripheral Pulse Contour Analysis in Determining Stroke Volume. Progress Report 5, Institute of Medical Physics, Da Costakade 45, Utrecht, Netherlands 1976, p. 59-62.
29. Chen C-H, Nevo E, Fetics B, Pak PH, Yin FCP, Maughan L, et al. Estimation of central aortic pressure waveform by mathematical transformation of radial tonometry pressure. Validation of generalized transfer function. Circulation 1997; 95:1827-1836.
30. Filipovsky J, Svobodova V, Pecen L. Reproducibility of radial pulse wave analysis in healthy subjects. J Hypertens 2000; 18:1033-1040.
31. Pauca AL, O'Rourke MF, Kon ND. Prospective evaluation of a method for estimating ascending aortic pressure from the radial artery pressure waveform. Hypertension 2001; 38:932-937.
32. Benetos A, Laflache A, Asmar R, Gautier S, Safar A, Safar ME. Arterial stiffness, hydrochlorothiazide and converting enzyme inhibition in essential hypertension. J Hum Hypertens 1996; 10:77-82.
33. Touyz RM, He G, Deng LY, Schiffrin EL. Role of extracellular signal-regulated kinases in angiotensin II-stimulated contraction of smooth muscle cells from human resistance arteries. Circulation 1999; 99:392-399.
34. Benetos A, Levy BI, Lacolley P, Taillard F, Duriez M, Safar ME. Role of angiotensin II and bradykinin on aortic collagen following converting enzyme inhibition in spontaneously hypertensive rats. Arterioscler Thromb Vasc Biol 1997; 17:3196-3201.
35. Thai HM, Goldman S, Gaballa M. Candesartan improves endothelium-dependent vasorelaxation in large arteries through endothelial nitric oxide synthase upregulation. Circulation 2000; 102(Suppl II): II-535.
36. Siraghy HM, DeGasparo M, Carey RM. Angiotensin type 2 receptor mediates valsartan-induced hypotension in conscious rats. Hypertension 2000; 35:1074-1077.
37. Muller DN, Mervaala EM, Dechend R, Fiebeler A, Park JK, Schmidt F, et al. Angiotensin II (AT1) receptor blockade reduces vascular tissue factor in angiotensin II-induced cardiac vasculopathy. Am J Pathol 2000; 157:111-122.
38. Ledingham JM, Laverty R. Remodelling of resistance arteries in genetically hypertensive rats by treatment with valsartan, an angiotensin II receptor antagonist. Clin Exp Pharmacol Physiol 1996; 23:576-578.
39. Schiffrin EL, Park JB, Intengan HD, Touyz RT. Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan. Circulation 2000; 101:1653-1659.
40. Blacher J, Asmar R, Djane S, London GM, Safar ME. Aortic pulse wave velocity as a marker of cardiovascular risk in hypertensive patients. Hypertension 1999; 33:1111-1117.
41. London GM, Blacher J, Pannier B, Guerin AP, Marchais SJ, Safar ME. Arterial wave reflections and survival in end-stage renal failure. Hypertension 2001; 38:434-438.
42. London GM, Pannier B, Guerin AP, Marchais SJ, Safar ME, Cuche JL. Cardiac hypertrophy, aortic compliance, peripheral resistance, and wave reflection in end-stage renal disease: Comparative effects of ACE inhibition and calcium channel blockade. Circulation 1994; 90:2786-2796.
43. Asmar RG, Pannier B, Santoni JP, Laurent S, London GM, Levy BI, et al. Reversion of cardiac hypertrophy and reduced arterial compliance after converting enzyme inhibition in essential hypertension. Circulation 1988; 78:941-950.