Synthesis of pyrazolo[4′,3′:5,6]pyrano[2,3-d]pyrimidine derivatives for antiviral evaluation

Archiv der Pharmazie

Volumn 340, Issue 5, 2007, Pages 236-243

  Shamroukh, Ahmed H ^a   Zaki, Magdi E A ^a   Morsy, Eman M H ^a   Abdel Motti, Faiza M ^a   Abdel Megeid, Farouk M E ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Acyclic nucleosides; Antiviral activities; Pyranopyrazoles; Pyrazoles; Pyrazolopyranopyrimidines

Indexed keywords

1 [3,7 DIMETHYL 4 (5 NITROPHENYL) 2,4 DIHYDROPYRAZOLO [4',3':5,6]PYRANO[2,3 D]PYRIMIDIN 5 YL] 3,4 DIMETHYL 3A,7A DIHYDRO 1H PYRANO[2,3 C]PYRAZOL 6 ONE; 2 ACETYL 3,7 DIMETHYL 4 (4 NITROPHENYL) 2,4 DIHYDROPYRAZOLO[4',3':5,6]PYRANO[2,3 D]PYRIMIDIN 5(6H) ONE; 3,7 DIMETHYL 2 (2 METHOXYETHYL) 4 (4 NITROPHENYL) 2,4 DIHYDROPYRAZOLO[4',3':5,6]PYRANO[2,3 D]PYRIMIDIN 5 OL; 3,7 DIMETHYL 4 (4 NITROPHENYL) 2,4 DIHYDROPYRAZOLO[4',3':5,6]PYRANO[2,3 D]PYRIMIDINE 5(6H) THIONE; 3,7 DIMETHYL 4 (4 NITROPHENYL) 2,4 DIHYDROPYRAZOLO[4',3':5,6]PYRANO[2,3 D]PYRIMIDINE DERIVATIVE; 5 (2 METHOXYETHYLSULFANYL) 3,7 DIMETHYL 4 (4 NITROPHENYL) 2,4 DIHYDROPYRAZOLO[4',3':5,6]PYRANO[2,3 D]PYRIMIDINE; 5 (3,5 DIMETHYLPYRAZOL 1 YL) 3,7 DIMETHYL 4 (4 NITROPHENYL) 2,4 DIHYDRO PYRAZOLO[4',3':5,6]PYRANO[2,3 D]PYRIMIDINE; 5 AMINO 1 [3,7 DIMETHYL 4 (4 NITROPHENYL) 2,4 DIHYDROPYRAZOLO[4',3':5,6]PYRANO[2,3 D]PYRIMIDIN 5 YL] 1H PYRAZOLE 4 CARBONITRILE; 5 AMINO 1 [3,7 DIMETHYL 4 (4 NITROPHENYL) 2,4 DIHYDROPYRAZOLO[4',3':5,6]PYRANO[2,3 D]PYRIMIDIN 5 YL] 1H PYRAZOLE DERIVATIVE; 5 AMINO 3 METHYL 1 [3,7 DIMETHYL 4 (4 NITROPHENYL) 2,4 DIHYDROPYRAZOLO[4',3':5,6]PYRANO[2,3 D]PYRIMIDIN 5 YL] 1H PYRAZOLE 4 CARBONITRILE; 5 AMINO 3 METHYLTHIO 1 [3,7 DIMETHYL 4 (4 NITROPHENYL) 2,4 DIHYDROPYRAZOLO[4',3':5,6]PYRANO[2,3 D]PYRIMIDIN 5 YL] 1H PYRAZOLE 4 CARBONITRILE; 6 AMINO 3 METHYL 4 (4 NITROPHENYL) 2,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CARBONITRILE; ACICLOVIR; ETHYL 5 AMINO 1 [3,7 DIMETHYL 4 (4 NITROPHENYL) 2,4 DIHYDROPYRAZOLO[4',3':5,6]PYRANO[2,3 D]PYRIMIDIN 5 YL] 1H PYRAZOLE 4 CARBOXYLATE; NUCLEOSIDE DERIVATIVE; PYRAZOLE DERIVATIVE; PYRAZOLO[4',3':5,6]PYRANO[2,3 D]PYRIMIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ACETYLATION; ACYLATION; ALKYLATION; ANTIVIRAL ACTIVITY; ARTICLE; CRYSTAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; HERPES SIMPLEX VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTIVIRAL AGENTS; HERPESVIRUS 1, HUMAN; PLAQUE ASSAY; PYRAZOLES; PYRIMIDINE NUCLEOSIDES; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS REPLICATION;

EID: 34250744683     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200700005     Document Type: Article

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