Effect of perinatal low protein diets on the ontogeny of select hepatic cytochrome P450 enzymes and cytochrome P450 reductase in the rat

Drug Metabolism and Disposition

Volumn 35, Issue 7, 2007, Pages 1057-1063

  Cherala, Ganesh ^a   Shapiro, Bernard H ^b   D'Mello, Anil P ^a  

^a UNIVERSITY OF THE SCIENCES   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN; CYTOCHROME P450 2C12; CYTOCHROME P450 ISOENZYME; CYTOCHROME P450 REDUCTASE; HEXOBARBITAL; LIVER ENZYME; OXYGENASE;

ANIMAL EXPERIMENT; ARTICLE; CEREAL; CONTROLLED STUDY; DIET; DRUG METABOLISM; ENZYME ACTIVITY; FEMALE; KINETICS; LACTATION; MALE; NONHUMAN; NUTRITION; NUTRITIONAL SCIENCE; ONTOGENY; PERINATAL CARE; PERINATAL PERIOD; PREGNANCY; PRIORITY JOURNAL; PROGENY; PROTEIN RESTRICTION; PUP (RODENT); RAT;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP2B1; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; DIET, PROTEIN-RESTRICTED; FEMALE; HEXOBARBITAL; HYPNOTICS AND SEDATIVES; LACTATION; LIVER; MALE; MATERNAL NUTRITION PHYSIOLOGY; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXAZINES; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; SEX FACTORS; SLEEP; STEROID HYDROXYLASES; TESTOSTERONE; TIME FACTORS;

RATTUS;

EID: 34250739401     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.106.013748     Document Type: Article

References (38)

1. Agrawal AK and Shapiro BH (2000) Latent overexpression of hepatic CYP2C7 in adult male and female rats neonatally exposed to phenobarbital: a developmental profile of gender-dependent P450s. J Pharmacol Exp Ther 293:1027-1033.
2. American Institute of Nutrition (1980) Second report of the Ad Hoc Committee on Standards for Nutritional Studies. J Nutr 110:1726.
3. Bagley DM and Hayes JR (1983) Neonatal phenobarbital administration results in increased cytochrome P450-dependent monooxygenase activity in adult male and female rats. Biochem Biophys Res Commun 114:1132-1137.
4. Barker DJ, Hales CN, Fall CH, Osmond C, Phipps K, and Clark PM (1993) Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth. Diabetologia 36:62-67.
5. Böcker R (1982) Rapid analysis of hexobarbital and its main metabolites in mice by high-performance liquid chromatography. J Chromatogr 228:350-354.
6. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
7. Burke MD and Mayer RT (1974) Ethoxyresorufin: direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene. Drug Metab Dispos 2:583-588.
8. Burke MD, Thompson S, Weaver RJ, Wolf CR, and Mayer RT (1994) Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver. Biochem Pharmacol 48:923-936.
9. Burns SP, Desai M, Cohen RD, Hales CN, Iles RA, Germain JP, Going TC, and Bailey RA (1997) Gluconeogenesis, glucose handling, and structural changes in livers of the adult offspring of rats partially deprived of protein during pregnancy and lactation. J Clin Invest 100:1768-1774.
10. Cancino-Badias L, Reyes RE, Nosti R, Perez I, Dorado V, Caballero S, Soria A, Camacho-Carranza R, Escobar D, and Espinosa-Aguirre JJ (2003) Modulation of rat liver cytochrome P450 by protein restriction assessed by biochemical and bacterial mutagenicity methods [corrected]. Mutagenesis 18:95-100.
11. Cherala G, Shapiro BH, and D'mello AP (2006) Two low protein diets differentially affect food consumption and reproductive performance in pregnant and lactating rats and long-term growth in their offspring. J Nutr 136:2827-2833.
12. Chow T, Imaoka S, Hiroi T, and Funae Y (1999) Developmental changes in the catalytic activity and expression of CYP2D isoforms in the rat liver. Drug Metab Dispos 27:188-192.
13. Desai M, Byrne CD, Meeran K, Martenz ND, Bloom SR, and Hales CN (1997) Regulation of hepatic enzymes and insulin levels in offspring of rat dams fed a reduced-protein diet. Am J Physiol 273:G899-G904.
14. Desai M, Crowther NJ, Ozanne SE, Lucas A, and Hales CN (1995) Adult glucose and lipid metabolism may be programmed during fetal life. Biochem Soc Trans 23:331-335.
15. Dhir RN and Shapiro BH (2003) Interpulse growth hormone secretion in the episodic plasma profile causes the sex reversal of cytochrome P450s in senescent male rats. Proc Natl Acad Sci U S A 100:15224-15228.
16. Holson RR and Pearce B (1992) Principles and pitfalls in the analysis of prenatal treatment effects in multiparous species. Neurotoxicol Teratol 14:221-228.
17. Imaoka S, Fujita S, and Funae Y (1991) Age-dependent expression of cytochrome P-450s in rat liver. Biochim Biophys Acta 1097:187-192.
18. Johnson TN, Tanner MS, and Tucker GT (2002) Developmental changes in the expression of enterocytic and hepatic cytochromes P4501A in rat. Xenobiotica 32:595-604.
19. Koop DR (1986) Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a. Mol Pharmacol 29:399-404.
20. Kronbach T, Mathys D, Gut J, Catin T, and Meyer UA (1987) High-performance liquid chromatographic assays for bufuralol 1′-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver. Anal Biochem 162:24-32.
21. Mode A and Gustafsson JA (2006) Sex and the liver - a journey through five decades. Drug Metab Rev 38:197-207.
22. Oinonen T and Lindros KO (1998) Zonation of hepatic cytochrome P-450 expression and regulation. Biochem J 329 (Pt 1):17-35.
23. Pampori NA and Shapiro BH (1994) Over-expression of CYP2C11, the major male-specific form of hepatic cytochrome P450, in the presence of nominal pulses of circulating growth hormone in adult male rats neonatally exposed to low levels of monosodium glutamate. J Pharmacol Exp Ther 271:1067- 1073.
24. Passos MC, da Fonte Ramos C, Dutra SC, Mouco T, and de Moura EG (2002) Long-term effects of malnutrition during lactation on the thyroid function of offspring. Horm Metab Res 34:40-43.
25. Phillips AH and Langdon RG (1962) Hepatic triphosphopyridine nucleotide-cytochrome c reductase: isolation, characterization, and kinetic studies. J Biol Chem 237:2652-2660.
26. Reeves PG, Nielsen FH, and Fahey GC Jr (1993) AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition Ad Hoc Writing Committee on the Reformulation of the AIN-76A Rodent Diet. J Nutr 123:1939-1951.
27. Ronis MJ, Rowlands JC, Hakkak R, and Badger TM (1999) Altered expression and glucocorticoid-inducibility of hepatic CYP3A and CYP2B enzymes in male rats fed diets containing soy protein isolate. J Nutr 129:1958-1965.
28. Ronis MJ, Rowlands JC, Hakkak R, and Badger TM (2001) Inducibility of hepatic CYP1A enzymes by 3-methylcholanthrene and isosafrole differs in male rats fed diets containing casein, soy protein isolate or whey from conception to adulthood. J Nutr 131:1180-1188.
29. Rosenberg DW (1991) Dietary modulation of cytochrome P450 in the small intestinal epithelium. Pharmacology 43:36-46.
30. Ryan DE and Levin W (1990) Purification and characterization of hepatic microsomal cytochrome P-450. Pharmacol Ther 45:153-239.
31. Schenkman JB and Griem H (1993) Cytochrome p450, Heidelberg, Springer-Verlag.
32. Shapiro BH and Szczotka SM (1984) Androgenic repression of hexobarbitone metabolism and action in Crl:CD-1 (ICR)BR mice. Br J Pharmacol 81:49-54.
33. Sonderfan AJ, Arlotto MP, Dutton DR, McMillen SK, and Parkinson A (1987) Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450. Arch Biochem Biophys 255:27-41.
34. Tassaneeyakul W, Veronese ME, Birkett DJ, and Miners JO (1993) High-performance liquid chromatographic assay for 4-nitrophenol hydroxylation, a putative cytochrome P-4502E1 activity, in human liver microsomes. J Chromatogr 616:73-78.
35. Wattenberg LW (1975) Effects of dietary constituents on the metabolism of chemical carcinogens. Cancer Res 35:3326-3331.
36. Waxman DJ, Morrissey JJ, and LeBlanc GA (1989) Female-predominant rat hepatic P-450 forms j (IIE1) and 3 (IIA1) are under hormonal regulatory controls distinct from those of the sex-specific P-450 forms. Endocrinology 124:2954-2966.
37. Zhang W, Parentau H, Greenly RL, Metz CA, Aggarwal S, Wainer IW, and Tracy TS (1999) Effect of protein-calorie malnutrition on cytochromes P450 and glutathione S-transferase. Eur J Drug Metab Pharmacokinet 24:141-147.
38. Zorrilla EP (1997) Multiparous species present problems (and possibilities) to developmentalists. Dev Psychobiol 30:141-150.