메뉴 건너뛰기




Volumn 27, Issue 2, 1999, Pages 188-192

Developmental changes in the catalytic activity and expression of CYP2D isoforms in the rat liver

Author keywords

[No Author keywords available]

Indexed keywords

BUFURALOL; CYTOCHROME P450; QUININE;

EID: 0032911164     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (32)

References (24)
  • 1
    • 0022510805 scopus 로고
    • Steady-state concentrations of imipramine and its metabolites in relation to the sparteine/debrisoquine polymorphism
    • Brosen K, Klysner R, Gram LF, Otton SV, Bech P and Bertilsson L (1986) Steady-state concentrations of imipramine and its metabolites in relation to the sparteine/debrisoquine polymorphism. Eur J Clin Pharmacol 30:679-684.
    • (1986) Eur J Clin Pharmacol , vol.30 , pp. 679-684
    • Brosen, K.1    Klysner, R.2    Gram, L.F.3    Otton, S.V.4    Bech, P.5    Bertilsson, L.6
  • 2
    • 0022869718 scopus 로고
    • Stereo- and regioselectivity of hepatic oxidation in man: Effect of the debrisoquine/sparteine phenotype on bufuralol hydroxylation
    • Dayer P, Leemann T, Kupher A, Kronbach T and Meyer UA (1986) Stereo- and regioselectivity of hepatic oxidation in man: Effect of the debrisoquine/sparteine phenotype on bufuralol hydroxylation. Eur J Clin Pharmacol 31:313-318.
    • (1986) Eur J Clin Pharmacol , vol.31 , pp. 313-318
    • Dayer, P.1    Leemann, T.2    Kupher, A.3    Kronbach, T.4    Meyer, U.A.5
  • 3
    • 0025305464 scopus 로고
    • The genetic polymorphism of debrisoquine metabolism: Clinical aspects
    • Eichelbaum E and Gross AS (1990) The genetic polymorphism of debrisoquine metabolism: Clinical aspects. Pharmacol Ther 46:377-394.
    • (1990) Pharmacol Ther , vol.46 , pp. 377-394
    • Eichelbaum, E.1    Gross, A.S.2
  • 4
    • 0021965297 scopus 로고
    • Simultaneous purification of multiple forms of rat liver microsomal cytochrome P-450 by high-performance liquid chromatography
    • Funae Y and Imaoka S (1985) Simultaneous purification of multiple forms of rat liver microsomal cytochrome P-450 by high-performance liquid chromatography. Biochim Biophys Acta 842:119-132.
    • (1985) Biochim Biophys Acta , vol.842 , pp. 119-132
    • Funae, Y.1    Imaoka, S.2
  • 5
    • 0023154962 scopus 로고
    • Debrisoquine 4-hydroxylase: Characterization of a new P450 gene subfamily, regulation, chromosomal mapping, and molecular analysis of the DNA rat polymorphism
    • Gonzalez FJ, Matsunaga E, Nagata K, Meyer UA, Nebert DW, Pastewka J, Kozak CA, Gillette JI, Gelboin HV and Hardwick JP (1987) Debrisoquine 4-hydroxylase: Characterization of a new P450 gene subfamily, regulation, chromosomal mapping, and molecular analysis of the DNA rat polymorphism. DNA 6:149-161.
    • (1987) DNA , vol.6 , pp. 149-161
    • Gonzalez, F.J.1    Matsunaga, E.2    Nagata, K.3    Meyer, U.A.4    Nebert, D.W.5    Pastewka, J.6    Kozak, C.A.7    Gillette, J.I.8    Gelboin, H.V.9    Hardwick, J.P.10
  • 7
    • 0032496338 scopus 로고    scopus 로고
    • Tissue distributions of CYP2D1, 2D2, 2D3 and 2D4 mRNA in rats detected by RT-PCR
    • Hiroi T, Imaoka S, Chow, T and Funae Y (1998) Tissue distributions of CYP2D1, 2D2, 2D3 and 2D4 mRNA in rats detected by RT-PCR. Biochim Biophys Acta 1380:305-312.
    • (1998) Biochim Biophys Acta , vol.1380 , pp. 305-312
    • Hiroi, T.1    Imaoka, S.2    Chow, T.3    Funae, Y.4
  • 8
    • 0025944787 scopus 로고
    • Age-dependent expression of cytochrome P-450s in rat liver
    • Imaoka S, Fujita S and Funae Y (1991) Age-dependent expression of cytochrome P-450s in rat liver. Biochim Biophys Acta 1097:187-192.
    • (1991) Biochim Biophys Acta , vol.1097 , pp. 187-192
    • Imaoka, S.1    Fujita, S.2    Funae, Y.3
  • 9
    • 0028902652 scopus 로고
    • cDNA cloning of a novel rat brain cytochrome P450 belonging to the CYP2D subfamily
    • Kawashima H and Strobel HW (1995) cDNA cloning of a novel rat brain cytochrome P450 belonging to the CYP2D subfamily. Biochem Biophys Res Commun 209:535-540.
    • (1995) Biochem Biophys Res Commun , vol.209 , pp. 535-540
    • Kawashima, H.1    Strobel, H.W.2
  • 10
    • 0025972040 scopus 로고
    • Regulation of the expression of the sex-specific isoforms of cylochrome P-450 in rat liver
    • Kobliakov V, Popova N and Rossi L (1991) Regulation of the expression of the sex-specific isoforms of cylochrome P-450 in rat liver. Eur J Biochem 195:585-591.
    • (1991) Eur J Biochem , vol.195 , pp. 585-591
    • Kobliakov, V.1    Popova, N.2    Rossi, L.3
  • 11
    • 0023258883 scopus 로고
    • High-performance liquid chromatographic assays for bufuralol 1′-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan o-demethylase in microsomal and purified cytochrome P-450 isozymes of human liver
    • Kronbach T, Mathys D, Gut J, Catin T and Meyer RA (1987) High-performance liquid chromatographic assays for bufuralol 1′-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan o-demethylase in microsomal and purified cytochrome P-450 isozymes of human liver. Anal Biochem 162:24-32.
    • (1987) Anal Biochem , vol.162 , pp. 24-32
    • Kronbach, T.1    Mathys, D.2    Gut, J.3    Catin, T.4    Meyer, R.A.5
  • 12
    • 0021332970 scopus 로고
    • Postnatal development of constitutive forms of cytochrome P-450 in liver microsomes of male and female rats
    • Maeda K, Kamataki T, Nagai T and Kato R (1984) Postnatal development of constitutive forms of cytochrome P-450 in liver microsomes of male and female rats. Biochem Pharmacol 33:509-512.
    • (1984) Biochem Pharmacol , vol.33 , pp. 509-512
    • Maeda, K.1    Kamataki, T.2    Nagai, T.3    Kato, R.4
  • 13
    • 0025310744 scopus 로고
    • Specific cytosine demethylation within the first exons of the rat CYP2D3 and CYP2D5 genes are associated with activation of hepatic gene expression during development
    • Matsunaga E and Gonzalez FJ (1990) Specific cytosine demethylation within the first exons of the rat CYP2D3 and CYP2D5 genes are associated with activation of hepatic gene expression during development. DNA Cell Biol 9:443-452.
    • (1990) DNA Cell Biol , vol.9 , pp. 443-452
    • Matsunaga, E.1    Gonzalez, F.J.2
  • 14
    • 0025164996 scopus 로고
    • The rat debrisoquine 4-hydroxylase CYP2D gene subfamily: Complete sequences of four closely linked genes and evidence that gene conversions maintained sequence homogeneity at the heme binding region of the cytochrome P450 active site
    • Matsunaga E, Umeno M and Gonzalez FJ (1990) The rat debrisoquine 4-hydroxylase CYP2D gene subfamily: Complete sequences of four closely linked genes and evidence that gene conversions maintained sequence homogeneity at the heme binding region of the cytochrome P450 active site. J Mol Evol 30:155-169.
    • (1990) J Mol Evol , vol.30 , pp. 155-169
    • Matsunaga, E.1    Umeno, M.2    Gonzalez, F.J.3
  • 15
    • 0024416946 scopus 로고
    • The CYP2D gene subfamily: Analysis of the molecular basis of the debrisoquine 4-hydroxylase deficiency in DA rats
    • Matsunaga E, Zanger UM, Hardwick JP, Gelboin HV, Meyer UA and Gonzalez FJ (1989) The CYP2D gene subfamily: Analysis of the molecular basis of the debrisoquine 4-hydroxylase deficiency in DA rats. Biochemistry 28:7349-7355.
    • (1989) Biochemistry , vol.28 , pp. 7349-7355
    • Matsunaga, E.1    Zanger, U.M.2    Hardwick, J.P.3    Gelboin, H.V.4    Meyer, U.A.5    Gonzalez, F.J.6
  • 16
    • 0021880264 scopus 로고
    • Expression of rat liver cytochrome P-450MC cDNA in Saccharomyces cerevisiae
    • Oeda K, Sakaki T and Ohkawa H (1985) Expression of rat liver cytochrome P-450MC cDNA in Saccharomyces cerevisiae. DNA 4:203-210.
    • (1985) DNA , vol.4 , pp. 203-210
    • Oeda, K.1    Sakaki, T.2    Ohkawa, H.3
  • 17
    • 0027440393 scopus 로고
    • Characterization of two P-450 isozymes placed in the rat CYP2D subfamily
    • Ohishi N, Imaoka S, Suzuki T and Funae Y (1993) Characterization of two P-450 isozymes placed in the rat CYP2D subfamily. Biochim Biophys Acta 1158:227-236.
    • (1993) Biochim Biophys Acta , vol.1158 , pp. 227-236
    • Ohishi, N.1    Imaoka, S.2    Suzuki, T.3    Funae, Y.4
  • 18
    • 78651165715 scopus 로고
    • The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
    • Omura T and Sato R (1964) The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J Biol Chem 239:2370-2318.
    • (1964) J Biol Chem , vol.239 , pp. 2370-12318
    • Omura, T.1    Sato, R.2
  • 19
    • 0026672248 scopus 로고
    • Organella-targeted expression of rat liver cytochrome P450c27 in yeast. Genetically engineered alteration of mitochondrial P450 into a microsomal form creates a novel functional electron transport chain
    • Sakaki T, Akiyoshi-Shibata M, Yabusaki Y and Ohkawa H (1992) Organella-targeted expression of rat liver cytochrome P450c27 in yeast. Genetically engineered alteration of mitochondrial P450 into a microsomal form creates a novel functional electron transport chain. J Biol Chem 267:16497-16502.
    • (1992) J Biol Chem , vol.267 , pp. 16497-16502
    • Sakaki, T.1    Akiyoshi-Shibata, M.2    Yabusaki, Y.3    Ohkawa, H.4
  • 20
    • 0024439395 scopus 로고
    • Physiological and pathophysiological alterations in rat hepatic cytochrome P-450
    • Schenkman JB, Thummel KE and Favreau LV (1989) Physiological and pathophysiological alterations in rat hepatic cytochrome P-450. Drug Metab Rev 20:557-584.
    • (1989) Drug Metab Rev , vol.20 , pp. 557-584
    • Schenkman, J.B.1    Thummel, K.E.2    Favreau, L.V.3
  • 21
    • 0022423245 scopus 로고
    • Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs : Genomic complexity and molecular evolution of the gene
    • Tso JY, Sun XH, Kao TH, Reece KS and Wu R (1985) Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs : Genomic complexity and molecular evolution of the gene. Nucleic Acids Res 13:2485-2502.
    • (1985) Nucleic Acids Res , vol.13 , pp. 2485-2502
    • Tso, J.Y.1    Sun, X.H.2    Kao, T.H.3    Reece, K.S.4    Wu, R.5
  • 22
    • 0031574143 scopus 로고    scopus 로고
    • Expression of four rat CYP2D isoforms in Saccharomyces cerevisiae and their catalytic activity
    • Wan J, Imaoka S, Chow T, Hiroi T, Yabusaki Y and Funae Y (1997) Expression of four rat CYP2D isoforms in Saccharomyces cerevisiae and their catalytic activity. Arch Biochem Biophys 348:383-390.
    • (1997) Arch Biochem Biophys , vol.348 , pp. 383-390
    • Wan, J.1    Imaoka, S.2    Chow, T.3    Hiroi, T.4    Yabusaki, Y.5    Funae, Y.6
  • 23
    • 0021947032 scopus 로고
    • Regulation of rat hepatic cytochrome P-450 : Age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes
    • Waxman DJ, Dannan GA and Guengerich FP (1985) Regulation of rat hepatic cytochrome P-450 : Age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes. Biochemistry 24:4409-4417.
    • (1985) Biochemistry , vol.24 , pp. 4409-4417
    • Waxman, D.J.1    Dannan, G.A.2    Guengerich, F.P.3
  • 24
    • 0026750647 scopus 로고
    • The human hepatic cytochrome P450 involved in drug metabolism
    • Wrighton SA and Stevens JC (1992) The human hepatic cytochrome P450 involved in drug metabolism. Crit Rev Toxicol 22:1-21.
    • (1992) Crit Rev Toxicol , vol.22 , pp. 1-21
    • Wrighton, S.A.1    Stevens, J.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.