Amidine analogues of melphalan: Synthesis, cytotoxic activity, and DNA binding properties

Archiv der Pharmazie

Volumn 340, Issue 5, 2007, Pages 251-257

  Bielawska, Anna ^a   Bielawski, Krzysztof ^a   Anchim, Tomasz ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

Amidines; Cytotoxicity; DNA binding; Melphalan; Topoisomerase 11

Indexed keywords

AMIDINE; AMSACRINE; CONGOCIDINE; DACTINOMYCIN; DISTAMYCIN A; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; MELPHALAN; MITOXANTRONE; THYMIDINE;

ARTICLE; BINDING AFFINITY; BREAST CANCER; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DNA SEQUENCE; DNA SYNTHESIS; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

AMIDINES; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DNA; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; DRUG SCREENING ASSAYS, ANTITUMOR; ETHIDIUM; HUMANS; INHIBITORY CONCENTRATION 50; MELPHALAN; STRUCTURE-ACTIVITY RELATIONSHIP; THYMIDINE;

EID: 34250719685     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200700001     Document Type: Article

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