Allelic and genotypic associations of DRD2 TaqI A polymorphism with heroin dependence in Spanish subjects: A case control study

Behavioral and Brain Functions

Volumn 3, Issue , 2007, Pages

  Perez de los Cobos, Jose ^a   Baiget, Montserrat ^a   Trujols, Joan ^a   Sinol, Nuria ^a   Volpini, Victor ^b   Banuls, Enrique ^a   Calafell, Francesc ^c   Luquero, Elena ^a   del Rio, Elisabeth ^a   Alvarez, Enric ^a  

^a HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^b BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

^c UNIVERSITAT POMPEU FABRA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; BENZODIAZEPINE DERIVATIVE; CANNABIS; COCAINE; DIAMORPHINE; DNA; DOPAMINE 2 RECEPTOR; METHADONE; TAQ POLYMERASE;

ADULT; ALLELE; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DRUG DEPENDENCE; EUROPE; FEMALE; GENDER BIAS; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SPAIN;

EID: 34250705799     PISSN: 17449081     EISSN: None     Source Type: Journal    
DOI: 10.1186/1744-9081-3-25     Document Type: Article

References (28)

1. Tsuang MT Lyons MJ Meyer JM Doyle T Eisen SA Goldberg J True W Lin N Toomey R Eaves L Co-occurrence of abuse of different drugs in men: The role of drug-specific and shared vulnerabilities Arch Gen Psychiatry 1998 55 967-2 10.1001/archpsyc.55.11.967 9819064
2. Merikangas KR Stolar M Stevens DE Goulet J Preisig MA Fenton B Zhang H O'Malley SS Rounsaville BJ Familial transmission of substance use disorders Arch Gen Psychiatry 1998 55 973-979 10.1001/archpsyc.55.11.973 9819065
3. Karkowski LM Prescott CA Kendler KS Multivariate assessment of factors influencing illicit substance use in twins from female-female pairs Am J Med Genet 2000 96 665-670 10.1002/ 1096-8628(20001009)96:5<665::AID-AJMG13>3.0.CO;2-O 11054775
4. Kendler KS Jacobson KC Prescott CA Neale MC Specificity of genetic and environmental risk factors for use and abuse/dependence of cannabis, cocaine, hallucinogens, sedatives, stimulants, and opiates in male twins Am J Psychiatry 2003 160 687-695 10.1176/appi.ajp.160.4.687 12668357
5. Wise RA Bozarth MA A psychomotor stimulant theory of addiction Psychol Rev 1987 94 469-492 10.1037/0033-295X.94.4.469 3317472
6. Koob GF Le Moal M Drug abuse: Hedonic homeostatic dysregulation Science 1997 278 52-58 10.1126/science.278.5335.52 9311926
7. Maldonado R Saiardi A Valverde O Samad TA Roques BP Borrelli E Absence of opiate rewarding effects in mice lacking dopamine D2 receptors Nature 1997 388 586-589 10.1038/41567 9252189
8. Noble EP Blum K Ritchie T Montgomery A Sheridan PJ Allelic association of the D2 dopamine receptor gene with receptor-binding characteristics in alcoholism Arch Gen Psychiatry 1991 48 648-654 2069496
9. Thompson J Thomas N Singleton A Piggott M Lloyd S Perry EK Morris CM Perry RH Ferrier IN Court JA D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: Reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele Pharmacogenetics 1997 7 479-484 10.1097/ 00008571-199712000-00006 9429233
10. Pohjalainen T Rinne JO Nagren K Lehikoinen P Anttila K Syvalahti EK Hietala J The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers Mol Psychiatry 1998 3 256-260 10.1038/sj.mp.4000350 9672901
11. Laruelle M Gelernter J Innis RB D2 receptors binding potential is not affected by Taq1 polymorphism at the D2 receptor gene Mol Psychiatry 1998 3 261-265 10.1038/sj.mp.4000343 9672902
12. Blum K Sheridan PJ Wood RC Braverman ER Chen TJ Cull JG Comings DE The D2 dopamine receptor gene as a determinant of reward deficiency syndrome J R Soc Med 1996 89 396-400 1295855 8774539
13. Volkow ND Wang GJ Fowler JS Logan J Gatley SJ Gifford A Hitzemann R Ding YS Pappas N Prediction of reinforcing responses to psychostimulants in humans by brain dopamine D2 receptor levels Am J Psychiatry 1999 156 1440-1443 10484959
14. Kaasinen V Nagren K Hietala J Farde L Rinne JO Sex differences in extrastriatal dopamine D2-like receptors in the human brain Am J Psychiatry 2001 158 308-311 10.1176/appi.ajp.158.2.308 11156817
15. Wang E Ding YC Flodman P Kidd JR Kidd KK Grady DL Ryder OA Spence MA Swanson JM Moyzis RK The genetic architecture of selection at the human dopamine receptor D4 (DRD4) gene locus Am J Hum Genet 2004 74 931-944 1181986 15077199 10.1086/420854
16. Young RM Lawford BR Nutting A Noble EP Advances in molecular genetics and the prevention and treatment of substance misuse: Implications of association studies of the A1 allele of the D2 dopamine receptor gene Addict Behav 2004 29 1275-1294 10.1016/j.addbeh.2004.06.012 15345265
17. Lawford BR Young RM Noble EP Sargent J Rowell J Shadforth S Zhang X Ritchie T The D2 dopamine receptor A1 allele and opioid dependence: association with heroin use and response to methadone treatment Am J Med Genet 2000 96 592-598 10.1002/ 1096-8628(20001009)96:5<592::AID-AJMG3>3.0.CO;2-Y 11054765
18. Shahmoradgoli Najafabadi M Ohadi M Joghataie MT Valaie F Riazalhosseini Y Mostafavi H Mohammadbeigi F Najmabadi H Association between the DRD2 A1 allele and opium addiction in the Iranian population Am J Med Genet B Neuropsychiatr Genet 2005 134 39-41 15704216
19. Li T Liu X Zhao J Hu X Ball DM Loh el-W Sham PC Collier DA Allelic association analysis of the dopamine D2, D3, 5-HT2A, and GABAAγ2 receptors and serotonin transporter genes with heroin abuse in Chinese subjects Am J Med Genet 2002 114 329-335 10.1002/ajmg.10200 11920858
20. Xu K Lichtermann D Lipsky RH Franke P Liu X Hu Y Cao L Schwab SG Wildenauer DB Bau CH Ferro E Astor W Finch T Terry J Taubman J Maier W Goldman D Association of specific haplotypes of D2 dopamine receptor gene with vulnerability to heroin dependence in 2 distinct populations Arch Gen Psychiatry 2004 61 597-606 10.1001/archpsyc.61.6.597 15184239
21. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders DSM-IV. American Psychiatric Association, Washington, D.C fourth 1994
22. Plan Nacional sobre Drogas (PND) Observatorio Español sobre Drogas Informe no 5 - Julio Ministerio del Interior, Delegación del Gobierno para el Plan Nacional sobre Drogas. Madrid 2002
23. Miller SA Dykes DD Polesky HF A simple salting out procedure for extracting DNA from human nucleated cells Nucleic Acids Res 1988 16 1215 334765 3344216 10.1093/nar/16.3.1215
24. Grandy DK Zhang Y Civelli O PCR detection of the TaqA RFLP at the DRD2 locus Hum Mol Genet 1993 2 2197 10.1093/hmg/2.12.2197-a 7906592
25. Caplehorn JRM Saunders JB A comparison of residential heroin detoxification patients and methadone maintenance patients Drug Alcohol Rev 1993 12 259-263 10.1080/09595239300185301 16840283
26. Limosin F Gorwood P Loze JY Dubertret C Gouya L Deybach JC Ades J Male limited association of the dopamine receptor D2 gene TaqI A polymorphism and alcohol dependence Am J Med Genet 2002 112 343 346 10.1002/ ajmg.10712 12376935
27. Lee HS Gender-specific molecular heterosis and association studies: dopamine D2 receptor gene and smoking Am J Med Genet B Neuropsychiatr Genet 2003 118 55-59 10.1002/ajmg.b.10036 12627467
28. Daly AK Candidate gene case-control studies Pharmacogenomics 2003 4 127- 139 10.1517/phgs.4.2.127.22629 12605547