Efficacy and safety of imidacloprid/moxidectin spot-on solution and fenbendazole in the treatment of dogs naturally infected with Angiostrongylus vasorum (Baillet, 1866)

Veterinary Parasitology

Volumn 147, Issue 3-4, 2007, Pages 258-264

  Willesen, J L ^a   Kristensen, A T ^a   Jensen, A L ^a   Heine, J ^b   Koch, J ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Research and Development Parasiticides   (Germany)

Author keywords

Angiostrongylus vasorum; Avermectines; Canine; Crenosoma vulpis; Fenbendazole; French heartworm; Imidacloprid; Moxidectin; Treatment

Indexed keywords

ADVOCATE; FENBENDAZOLE; IMIDACLOPRID; MOXIDECTIN; UNCLASSIFIED DRUG;

ANGIOSTRONGYLUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIARRHEA; DISEASE SEVERITY; DOG DISEASE; DRUG EFFICACY; DRUG SAFETY; FEMALE; FIELD STUDY; GASTROINTESTINAL DISEASE; MALE; NONHUMAN; SALIVATION; SINGLE DRUG DOSE; STRONGYLOIDIASIS; THORAX RADIOGRAPHY; TREATMENT DURATION; TREATMENT OUTCOME; VOMITING;

ADMINISTRATION, TOPICAL; ANGIOSTRONGYLUS; ANIMALS; ANTHELMINTICS; DOG DISEASES; DOGS; DRUG THERAPY, COMBINATION; FEMALE; FENBENDAZOLE; IMIDAZOLES; MACROLIDES; MALE; NITRO COMPOUNDS; STRONGYLIDA INFECTIONS;

ANGIOSTRONGYLUS VASORUM; CANIS FAMILIARIS; CRENOSOMA VULPIS;

EID: 34250689927     PISSN: 03044017     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetpar.2007.05.001     Document Type: Article

References (22)

1. Anon, 2005. Advocate Product Information. Bayer HealthCare AG, 51368 Leverkusen, Germany. http://www.emea.europa.eu/vetdocs/vets/Epar/advocate/advocate.htm.
2. Boag A.K., Lamb C.R., Chapman P.S., and Boswood A. Radiographic findings in 16 dogs infected with Angiostrongylus vasorum. Vet. Rec. 154 (2004) 426-430
3. Bolt G., Monrad J., Koch J., and Jensen A.L. Canine angiostrongylosis-A review. Vet. Rec. 135 (1994) 447-452
4. Caruso J.P., and Prestwood A.K. Immunopathogenesis of canine angistrongylosis: pulmonary effects of infection. Comp. Immunol. Microbiol. Infect. Dis. 11 (1988) 85-92
5. Chapman P.S., Boag A.K., Guitian J., and Boswood A. Angiostrongylus vasorum infection in 23 dogs (1999-2002). J. Small Anim. Pract. 45 (2004) 435-440
6. Conboy G. Natural infections of Crenosoma vulpis and Angiostrongylus vasorum in dogs in Atlantic Canada and their treatment with milbemycin oxime. Vet. Rec. 155 (2004) 16-18
7. Conboy, G., Schenker, R., Strehlau, G., 2004. Efficacy of Milbemax (Milbemycin/Praziquantel) for the treatment and prevention of Angiostrongylus vasorum infection in Dogs. Proceeding at the AAVP 49th Meeting, p. 92.
8. Craigh R.E., and Anderson R.C. The genus Crenosoma (Nematoda: Metastrongyloidea) in New World Mammals. Can. J. Zool. 50 (1972) 1555-1561
9. European Agency for the Evaluation of Medical Products, 2000. Guideline on Good Clinical Practice (GCP). VICH Topic GL9. http://www.emea.europa.eu/pdfs/vet/vich/059598en.pdf.
10. Garosi L.S., Platt S.R., McConnell J.F., Wrayt J.D., and Smith K.C. Intracranial haemorrhage associated with Angiostrongylus vasorum infection in three dogs. J. Small Anim. Pract. 46 (2005) 93-99
11. Jacobs D.E., Arakawa A., Courtney C.H., Gemmell M.A., McCall J.W., Myers G.H., and Vanparijs O. World association for the advancement of veterinary parasitology (W. A. A. V. P.) guidelines for evaluating the efficacy of anthelmintics for dogs and cats*1. Vet. Parasitol. 52 (1994) 179-202
12. Martin M.W.S., Ashton G., Simpson V.R., and Neal C. Angiostrongylosis in Cornwall-clinical presentations of eight cases. J. Small Anim. Pract. 34 (1993) 20-25
13. Morgan E.R., Shaw S.E., Brennan S.F., De Waal T.D., Jones B.R., and Mulcahy G. Angiostrongylus vasorum: a real heartbreaker. Trends Parasitol. 21 (2005) 49-51
14. Novotny M.J., Krautmann M.J., Ehrhart J.C., Godin C.S., Evans E.I., McCall J.W., Sun F., Rowan T.G., and Jernigan A.D. Safety of selamectin in dogs. Vet. Parasitol. 91 (2000) 377-391
15. Patteson M.W., Gibbs C., Wotton P.R., and Day M.J. Angiostrongylus-vasorum infection in 7 dogs. Vet. Rec. 133 (1993) 565-570
16. Paul A.J., Hutchens D.E., Firkins L.D., and Borgstrom M. Dermal safety study with imidacloprid/moxidectin topical solution in the ivermectin-sensitive collie. Vet. Parasitol. 121 (2004) 285-291
17. Paul A.J., Tranquilli W.J., and Hutchens D.E. Safety of moxidectin in avermectin-sensitive collies. Am. J. Vet. Res. 61 (2000) 482-483
18. Prestwood A.K., Greene C.E., Mahaffey E.A., and Burgess D.E. Experimental Canine Angiostrongylosis. 1. Pathologic manifestations. J. Am. Anim. Hosp. Assoc. 17 (1981) 491-497
19. Ridyard, A., 2005. Heartworm and lungworm in dogs and cats in the UK (vol. 27, p. 147, 2005). In Pract., 27, 237-237.
20. Rosen L., Ash L.R., and Wallace G.D. Life History of Canine Lungworm Angiostrongylus-Vasorum (Baillet). Am. J. Vet. Res. 31 (1970) 131-141
21. Wessmann A., Lu D., Lamb C.R., Smyth B., Mantis P., Chandler K., Boag A., Cherubini G.B., and Cappello R. Brain and spinal cord haemorrhages associated with Angiostrongylus vasorum infection in four dogs. Vet. Rec. 158 (2006) 858-863
22. Willesen J., Møller J., Koch J., Jensen A.L., and Kristensen A.T. Early diagnosis of Angiostrongylus vasorum (French Heartworm) and Crenosoma vulpis (fox lungworm) in dogs is possible by means of modified Baermann technique (in Danish). Dansk. Vet. Tid. 87 (2004) 6-10