Antihyperglycaemic and antiperoxidative effect of Helicteres isora L. bark extracts in streptozotocin-induced diabetic rats

Journal of Applied Biomedicine

Volumn 5, Issue 2, 2007, Pages 97-104

  Kumar, Ganesan ^a,c   Banu, Gani Sharmila ^b   Murugesan, Arunachalam Ganesan ^a   Pandian, Moses Rajasekara ^b  

^a MANONMANIAM SUNDARANAR UNIVERSITY   (India)

^b MUTHAYAMMAL COLLEGE OF ARTS AND SCIENCE   (India)

^c Selvam Arts and Science College   (India)

Author keywords

Antihyperglycaemic activity; Antioxidant potential; Helicteres isora; Streptozotocin

Indexed keywords

ANTIDIABETIC AGENT; CATALASE; FREE RADICAL; GLUCOSE; GLUTATHIONE; HELICTERES IGORA EXTRACT; PLANT EXTRACT; STREPTOZOCIN; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TOLBUTAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BARK; BODY WEIGHT; BRAIN; CONTROLLED STUDY; DIABETES MELLITUS; DOSE RESPONSE; DRUG DOSE INCREASE; DRUG MECHANISM; ENZYME ACTIVITY; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HELICTERES IGORA; HYPOGLYCEMIA; IN VIVO STUDY; KIDNEY; LD 50; LIVER; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; RAT; STERCULIACEAE; STREPTOZOCIN DIABETES; TOXICITY TESTING;

ANIMALIA; HELICTERES ISORA; RATTUS;

EID: 34250663050     PISSN: 1214021X     EISSN: 12140287     Source Type: Journal    
DOI: 10.32725/jab.2007.014     Document Type: Article

References (31)

1. Anuradha CV, Selvam R: Effect of oral methionine on tissue lipid peroxidation and antioxidants in alloxan induced diabetic rats. J. Nutr. Biochem. 4:212-217, 1993.
2. Baynes JW: Role of oxidative stress in development of complications in diabetes. Diabetes 40:405-412, 1991.
3. Brownlee M, Cerami A: The biochemistry of the complications of diabetes mellitus. Annu. Rev. Biochem. 50:385-432, 1981.
4. Cetto AA, Weidenfeld H, Revilla MC, Sergio IA: Hypoglycemic effect of Equisetum mriochaetum aerial parts on STZ diabetic rats. J. Ethnopharmacol. 72:129-133, 2000.
5. Chopra RN, Nayar SL, Chopra IC: Glossary of Indian Medicinal Plants (1st ed.), CSIR, New Delhi, India 1956, p. 131.
6. Duncan BD: Multiple range tests for correlated and heteroscedastic means. Biometrics 13:359-364, 1957.
7. Ellman GL: Tissue sulfhydryl groups. Arch. Biochem. Biophys. 82:70-77, 1959.
8. Ewart RBL, Kornfeld S, Kipnis DM: Effect of lectins on hormone release from isolated rat islets of langerhans. Diabetes 24:705-714, 1975.
9. Ghosh MN: Fundamentals of Experimental Pharmacology (2nd ed.), Scientific Book Agency, Calcutta 1984.
10. Kakkar P, Das B, Viswanathan PN: A modified spectrophotometric assay of SOD. Indian. J. Biochem.Biophys. 21:130-132, 1978.
11. Kakkar R, Kalra J, Mantha SV, Prasad K: Lipid peroxidation and activity of antioxidant enzymes in diabetic rats. Mol. Cell. Biochem. 151:113-119, 1995.
12. Kamtchouing P, Sokeng SD, Moundipa PF, Watcho P, Jatsa HB, Lontsi D: Protective role of Anacardium occidentale extract against streptozotocin-induced diabetes in rats. J. Ethnopharmacol. 62:95-99, 1998.
13. Kirtikar KF, Basu BD: Indian Medicinal Plants. Vol.1, International book distributors, Dehradun, India 1995, pp. 371-372.
14. Kumar G, Murugesan AG, Rajasekara Pandian M: Effect of Helicteres isora bark extract on blood glucose and hepatic enzymes in experimental diabetes. Pharmazie 61:353-355, 2006a.
15. Kumar G, Sharmila Banu G, Murugesan AG, Rajasekara Pandian M: Hypoglycaemic effect of Helicteres isora bark extract in rats. J. Ethnopharmacol. 107:304-307, 2006b.
16. Matcovis B, Varga SI, Szaluo L, Witsas H: The effect of diabetes on the activities of the peroxide metabolic enzymes. Horm. Metab. Res. 14:77-79, 1982.
17. Mazunder UK, Gupta M, Rajeshwar Y: Antihyperglycemic effect and antioxidant potential of Phyllanthus niruri (Euphorbiaceae) in streptozotocin induced diabetic rats. Eur. Bull. Drug Res. 13:1-9, 2005.
18. McCrod JM, Keele BB, Fridovich I Jr.: An enzyme based theory of obligate anaerobiosis; the physiological functions of superoxide dismutase. Proc. Natl. Acad. Sci. U.S.A. 68:1024-1027, 1976.
19. Meneghini R: Genotoxicity of active oxygen species in mammalian cells. Mutat. Res. 195:215-230, 1988.
20. National Institute of Health Guide for the Care and Use of Laboratory Animals. DHEW Publication (NIH), revised, Office of Science and Health Reports, DRR/NIH, Bethesda, USA, 1985.
21. Nichans WG, Samuelson B: Formation of MDA from phospholipid arachidonate during microsomal lipid peroxidation. Eur. J. Biochem. 6:126-130, 1968.
22. Nistico G, Cirilol HR, Fiskin K, Iannone M, Martino A, Rotilio G: NGF restores decrease in catalase activity and increases superoxide dismutase and glutathione peroxidase activity in the brain of aged rats. Free Radic. Biol. Med. 12:177-181, 1992.
23. Pohocha N, Grampurohit ND: Antispasmodic activity of the fruits of Helicteres isora Linn. Phytother. Res. 15:49-52, 2001.
24. Rakieten N, Rakieten ML, Nadkarni MV: Studies on the diabetogenic action of streptozotocin. Cancer Chemother. Rep. 29:91-98, 1963.
25. Rates SM: Plants as source of drugs. Toxicon 39:603-613, 2001.
26. Sasaki T, Matsui S, Sonae A: Effect of acetic acid concentration of a colour reaction in the O-toludine-boric acid method for blood glucose estimation. Rinshokagaku 1:346-353, 1972.
27. Siddique O, Sun Y, Lin JC, Chien YW: Facilitated transdermal transport of insulin. J. Pharm. Sci. 76:341-345, 1987.
28. Sinha KA: Colorimetric assay of catalase. Anal. Biochem. 47:389-394, 1972.
29. Slater TF: Free-radical mechanisms in tissue injury. J. Biochem. 222:1-15, 1984.
30. Vuillaume M: Reduced oxygen species, mutation, induction and cancer initiation. Mutat. Res. 186:43-72, 1987.
31. Zimmet PZ: Diabetes epidemiology as a tool to trigger diabetes research and care. Diabetologia 42:499-518, 1999.