Exaggerated Ambulatory Blood Pressure Variability Is Associated with Cognitive Dysfunction in the Very Elderly and Quality of Life in the Younger Elderly

American Journal of Hypertension

Volumn 20, Issue 7, 2007, Pages 720-727

  Sakakura, Kenichi ^a,b   Ishikawa, Joji ^a   Okuno, Masataka ^c   Shimada, Kazuyuki ^a   Kario, Kazuomi ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b Kiwa Public Clinic   (Japan)

^c Kamishima Public Clinic   (Japan)

Author keywords

Blood pressure variability; cognitive dysfunction; quality of life; very elderly

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BLOOD PRESSURE MONITORING; BLOOD PRESSURE VARIABILITY; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE EXACERBATION; FEMALE; GERIATRIC PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MINI MENTAL STATE EXAMINATION; NEUROPSYCHOLOGICAL TEST; OUTCOME ASSESSMENT; PRIORITY JOURNAL; QUALITY OF LIFE; SAMPLE SIZE; SHORT FORM 36; SYSTOLIC BLOOD PRESSURE;

AGED; AGED, 80 AND OVER; AGING; BLOOD PRESSURE; BLOOD PRESSURE MONITORING, AMBULATORY; COGNITION DISORDERS; FEMALE; HEALTH SURVEYS; HUMANS; MALE; MIDDLE AGED; QUALITY OF LIFE; SYSTOLE;

EID: 34250659678     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjhyper.2007.02.001     Document Type: Article

References (32)

1. Kikuya M., Hozawa A., Ohokubo T., Tsuji I., Michimata M., Matsubara M., Ota M., Nagai K., Araki T., Satoh H., Ito S., Hisamichi S., and Imai Y. Prognostic significance of blood pressure and heart rate variabilities: the Ohasama study. Hypertension 36 (2000) 901-906
2. Kanemaru A., Kanemaru K., and Kuwajima I. The effects of short-term blood pressure variability and nighttime blood pressure levels on cognitive function. Hypertens Res 24 (2001) 19-24
3. Bellelli G., Pezzini A., Bianchetti A., and Trabucchi M. Increased blood pressure variability may be associated with cognitive decline in hypertensive elderly subjects with no dementia. Arch Intern Med 162 (2002) 483-484
4. Frattola A., Parati G., Cuspidi C., Albini F., and Mancia G. Prognostic value of 24-hour blood pressure variability. J Hypertens 11 (1993) 1133-1137
5. Sander D., Kukla C., Klingelhofer J., Winbeck K., and Conrad B. Relationship between circadian blood pressure patterns and progression of early carotid atherosclerosis: a 3-year follow-up study. Circulation 102 (2000) 1536-1541
6. Elias M.F., Wolf P.A., D'Agostino R.B., Cobb J., and White L.R. Untreated blood pressure level is inversely related to cognitive functioning: the Framingham Study. Am J Epidemiol 138 (1993) 353-364
7. Harrington F., Saxby B.K., McKeith I.G., Wesnes K., and Ford G.A. Cognitive performance in hypertensive and normotensive older subjects. Hypertension 36 (2000) 1079-1082
8. Forette F., Seux M.L., Staessen J.A., Thijs L., Birkenhager W.H., Babarskiene M.R., Babeanu S., Bossini A., Gil-Extremera B., Girerd X., Laks T., Lilov E., Moisseyev V., Tuomilehto J., Vanhanen H., Webster J., Yodfat Y., and Fagard R. Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial. Lancet 352 (1998) 1347-1351
9. Fernandez-Lopez J.A., Siegrist J., Hernandez-Mejia R., Broer M., and Cueto-Espinar A. Study of quality of life on rural hypertensive patients. Comparison with the general population of the same environment. J Clin Epidemiol 47 (1994) 1373-1380
10. Lawrence W.F., Fryback D.G., Martin P.A., Klein R., and Klein B.E. Health status and hypertension: a population-based study. J Clin Epidemiol 49 (1996) 1239-1245
11. Roca-Cusachs A., Dalfo A., Badia X., Aristegui I., and Roset M. Relation between clinical and therapeutic variables and quality of life in hypertension. J Hypertens 19 (2001) 1913-1919
12. Amery A., Birkenhager W., Brixko P., Bulpitt C., Clement D., Deruyttere M., De Schaepdryver A., Dollery C., Fagard R., Forette F., Hamdy R., Joossens J.V., Lund-Johansen P., Petrie J., Tuomilehto J., and Williams B. Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly trial. Lancet 1 (1985) 1349-1354
13. Dahlof B., Lindholm L.H., Hansson L., Schersten B., Ekbom T., and Wester P.O. Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension). Lancet 338 (1991) 1281-1285
14. SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). SHEP Cooperative Research Group. JAMA 265 (1991) 3255-3264
15. Staessen J.A., Fagard R., Thijs L., Celis H., Arabidze G.G., Birkenhager W.H., Bulpitt C.J., de Leeuw P.W., Dollery C.T., Fletcher A.E., Forette F., Leonetti G., Nachev C., O'Brien E.T., Rosenfeld J., Rodicio J.L., Tuomilehto J., Zanchetti A., and The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. Lancet 350 (1997) 757-764
16. Bulpitt C.J., Beckett N.S., Cooke J., Dumitrascu D.L., Gil-Extremera B., Nachev C., Nunes M., Peters R., Staessen J.A., and Thijs L. Results of the pilot study for the Hypertension in the Very Elderly Trial. J Hypertens 21 (2003) 2409-2417
17. Gueyffier F., Bulpitt C., Boissel J.P., Schron E., Ekbom T., Fagard R., Casiglia E., Kerlikowske K., Coope J., and INDANA Group. Antihypertensive drugs in very old people: a subgroup meta-analysis of randomised controlled trials. Lancet 353 (1999) 793-796
18. Palatini P., Frigo G., Bertolo O., Roman E., Da Corta R., and Winnicki M. Validation of the A&D TM-2430 device for ambulatory blood pressure monitoring and evaluation of performance according to subjects' characteristics. Blood Press Monit 3 (1998) 255-260
19. Folstein M.F., Folstein S.E., and McHugh P.R. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12 (1975) 189-198
20. Fure B., Bruun Wyller T., Engedal K., and Thommessen B. Cognitive impairments in acute lacunar stroke. Acta Neurol Scand 114 (2006) 17-22
21. Perneczky R., Wagenpfeil S., Komossa K., Grimmer T., Diehl J., and Kurz A. Mapping scores onto stages: mini-mental state examination and clinical dementia rating. Am J Geriatr Psychiatry 14 (2006) 139-144
22. Wilber S.T., Lofgren S.D., Mager T.G., Blanda M., and Gerson L.W. An evaluation of two screening tools for cognitive impairment in older emergency department patients. Acad Emerg Med 12 (2005) 612-616
23. Dufouil C., Clayton D., Brayne C., Chi L.Y., Dening T.R., Paykel E.S., O'Connor D.W., Ahmed A., McGee M.A., and Huppert F.A. Population norms for the MMSE in the very old: estimates based on longitudinal data. Mini-Mental State Examination. Neurology 55 (2000) 1609-1613
24. Fukuhara S., Bito S., Green J., Hsiao A., and Kurokawa K. Translation, adaptation, and validation of the SF-36 Health Survey for use in Japan. J Clin Epidemiol 51 (1998) 1037-1044
25. Fukuhara S., Ware Jr. J.E., Kosinski M., Wada S., and Gandek B. Psychometric and clinical tests of validity of the Japanese SF-36 Health Survey. J Clin Epidemiol 51 (1998) 1045-1053
26. Fukuhara S., and Suzukamo Y. Manual of SF-36v2 Japanese version (2004), Institute for Health Outcomes & Process Evaluation Research, Kyoto
27. Rozzini L., Chilovi B.V., Bertoletti E., Conti M., Del Rio I., Trabucchi M., and Padovani A. Angiotensin converting enzyme (ACE) inhibitors modulate the rate of progression of amnestic mild cognitive impairment. Int J Geriatr Psychiatry 21 (2006) 550-555
28. Zanchetti A., and Elmfeldt D. Findings and implications of the Study on COgnition and Prognosis in the Elderly (SCOPE)-a review. Blood Press 15 (2006) 71-79
29. Kario K., Eguchi K., Hoshide S., Hoshide Y., Umeda Y., Mitsuhashi T., and Shimada K. U-curve relationship between orthostatic blood pressure change and silent cerebrovascular disease in elderly hypertensives: orthostatic hypertension as a new cardiovascular risk factor. J Am Coll Cardiol 40 (2002) 133-141
30. Waldstein S.R., Siegel E.L., Lefkowitz D., Maier K.J., Brown J.R., Obuchowski A.M., and Katzel L.I. Stress-induced blood pressure reactivity and silent cerebrovascular disease. Stroke 35 (2004) 1294-1298
31. Goldstein I.B., Bartzokis G., Guthrie D., and Shapiro D. Ambulatory blood pressure and the brain: a 5-year follow-up. Neurology 64 (2005) 1846-1852
32. Volicer L., Harper D.G., Manning B.C., Goldstein R., and Satlin A. Sundowning and circadian rhythms in Alzheimer's disease. Am J Psychiatry 158 (2001) 704-711