Repeated aerosol-vapor JP-8 jet fuel exposure affects neurobehavior and neurotransmitter levels in a rat model

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 70, Issue 14, 2007, Pages 1203-1213

  Baldwin, Carol M ^a   Figueredo, Aurelio J ^b   Wright, Lynda S ^c   Wong, Simon S ^d   Witten, Mark L ^d  

^a ARIZONA STATE UNIVERSITY   (United States)

^b University of Arizona   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; FUEL; NEUROTRANSMITTER;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AROUSAL; ARTICLE; AUTONOMIC NERVOUS SYSTEM; BRAIN REGION; COGNITION; COMPARATIVE STUDY; CONTROLLED STUDY; DOPAMINE METABOLISM; DOPAMINE RELEASE; ENVIRONMENTAL PROTECTION; ETHOLOGY; EXPOSURE; HIPPOCAMPUS; LONGITUDINAL STUDY; MALE; NERVE CELL EXCITABILITY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; REARING; STATISTICAL MODEL; URINE VOLUME; VAPOR;

3,4-DIHYDROXYPHENYLACETIC ACID; ADMINISTRATION, INHALATION; AEROSOLS; AIR POLLUTANTS, OCCUPATIONAL; ANALYSIS OF VARIANCE; ANIMALS; AROUSAL; BEHAVIOR, ANIMAL; BODY WEIGHT; DISEASE MODELS, ANIMAL; HYDROCARBONS; LINEAR MODELS; MOTOR ACTIVITY; NEUROTRANSMITTER AGENTS; RATS; RATS, INBRED F344;

ANIMALIA; RATTUS;

EID: 34250643507     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390701380872     Document Type: Article

References (48)

1. Antelman, S. M. 1994. Time-dependent sensitization in animals: A possible model of multiple chemical sensitivity in humans. Toxicol. Ind. Health 10:335-342.
2. Antelman, S. M., Kocan, D., Knopf, S., Edwards, D. J., and Caggiula, A. R. 1992. One brief exposure to a psychological stressor induces long-lasting, time-dependent sensitization of both the cataleptic and neurochemical responses to haloperidol. Life Sci. 51:261-266.
3. Antelman, S. M., Soares, J. C., and Gershon, S. 1997. Time-dependent sensitization - Possible implications for clinical psychopharmacology. Behav. Pharmacol. 8:505-514.
4. Austin, M. C., and Kalivas, P. W. 1991. Dopaminergic involvement in locomotion elicited from the ventral pallidum/substantia innominata. Brain Res. 542:123-131.
5. Baldwin, C. M., Bell, I. R., Fernandez, M., and Schwartz, G. E. 2000. Multiple chemical sensitivity. In Women and health, eds. M. B. Goldman and M. C. Hatch, pp. 1129-1139. San Diego, CA: Academic Press.
6. Baldwin, C. M., Houston, F. P., Podgornik, M. N., Young, R. S., Barnes, C. A., and Witten, M. L. 2001. Effects of aerosol-vapor JP-8 jet fuel on the Functional Observational Battery, and learning and memory in the rat. Arch. Environ. Health 56:216-226.
7. Bell, I. R., Baldwin, C. M., and Schwartz, G. E. 1998a. Illness from low levels of environmental chemicals: Relevance to chronic fatigue syndrome and fibromyalgia. Am. J. Med. 105:74S-82S.
8. Bell, I. R., Baldwin, C. M., and Schwartz, G. E. 2001. Sensitization studies in chemically intolerant individuals: Implications for individual difference research. Ann. NY Acad. Sci. 933:38-47.
9. Bell, I. R., Brooks, A. J., Baldwin, C. M., Fernandez, M., Figueredo, A. J., and Witten, M. L. 2005. JP-8 jet fuel exposure and divided attention test performance in 1991 Gulf War Veterans. Aviat. Space Environ. Med. 76:1136-1144.
10. Bell, I. R., Rossi J. III, Gilbert, M. E., Kobal, G., Morrow, L. A., Newlin, D. B., Sorg, B. A., and Wood, R. W. 1997. Testing the neural sensitization and kindling hypothesis for illness from low levels of environmental chemicals. Environ. Health Perspect. 105(suppl. 2):539-547.
11. Bell, I. R., Warg-Damiani, L., Baldwin, C. M., Walsh, M. E., and Schwartz, G. E. 1998b. Self-reported chemical sensitivity and wartime chemical exposures in Gulf War veterans with and without decreased global health ratings. Mil. Med. 163:725-732.
12. Caggiula, A. R., Antelman, S. M., Kucinski, B. J., Fowler, H., Edwards, D. J., Austin, M. C., Gershon, S., and Stiller, R. 1998. Oscillatory- sensitization model of repeated drug exposure: Cocaine's effects on shock-induced hypoalgesia. Prog. Neuro-Psychopharmacol. Biol. Psychiat. 22:511-521.
13. Caggiula, A. R., Antelman, S. M., Palmer, A. M., Kiss, S., Edwards, D. J., and Kocan, D. 1996. The effects of ethanol on striatal dopamine and frontal cortical D-[3H]aspartate efflux oscillate with repeated treatment. Relevance to individual differences in drug responsiveness. Neuropsychopharmacology 15:125-132.
14. Cohen, J., and Cohen, P. 1983. Applied multiple regression/correlation analysis for the behavioral sciences, 2nd ed. Hillsdale, NJ: Lawrence Erlbaum Associates.
15. Colotla, V. A., Lorenzana-Jiminez, M., and Rodriguez, R. 1980. Toward a behavioral toxicology of paint thinner. Neurobehav. Toxicol. 2:31-36.
16. Coull, J. T. 1998. Neural correlates of attention and arousal: Insights from electrophysiology, functional neuroimaging and psychopharmacology. Prog. Neruobiol. 55:343-361.
17. Elwan, M. A., and Soliman, M. R. 1995. Alteration of D1 and D2 dopaminergic receptor kinetics in specific rat brain regions following repeated administration of opiates. Pharmacology 51:73-83.
18. Espinoza, L. A., Valikhani, M., Cossio, M. J., Carr, T., Jung, M., Hyde, J., Witten, M. L., and Smulson, M. E. 2005. Altered expression of gamma-synuclein and detoxification-related genes in lungs of rats exposed to JP-8. Am. J. Respir. Cell Mol. Biol. 3:192-200.
19. Ferger. B., and Kuschinsky, K. 1996. Effects of cocaine on the EEG power spectrum of rats are significantly altered after its repeated administration: Do they reflect sensitization phenomena? Naunyn-Schmeideberg's Arch. Pharmacol. 353:545-551.
20. Figueredo, A. J., Petronovich, L., and Ross, D. M. 1992. The quantitative ethology of the Zebra finch: A study in comparative psychometrics. Multivariate Behav. Res. 27:413-436.
21. Gorsuch, R. L. (1983). Factor analysis. Hillsdale, NJ: Lawrence Erlbaum.
22. Harris, D. T., Sakiestewa, D., Robledo, R. F., and Witten, M. L. 1997. Immunotoxicological effects of JP-8 jet fuel exposure. Toxicol. Ind. Health 13:43-55.
23. Hays, A. M., Parliman, G., Pfaff, J. K., Lantz, R. C., Tinajero, J., Tollinger, B., Hall, J. N., and Witten, M. L. 1995. Changes in lung permeability correlate with lung histology in a chronic exposure model. Toxicol. Ind. Health 11:325-336.
24. Kalivas, P. W. 1992. Neural substrate of sensitization to psychostimulants. Clin. Neuropharmacol. 15:648A-649A.
25. Kalivas, P. W., and Duffy, P. 1988. Effects of daily cocaine and morphine treatment on somatodendritic and terminal field dopamine release. J. Neurochem. 50:1498-1504.
26. Kalivas, P. W., and Stewart, J. 1991. Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity. Brain Res. Rev. 16:223-244.
27. Knave, B., Persson, H. E., Goldberg, J. M., and Westerholm, P. 1976. Long-term exposure to jet fuel: An investigation on occupationally exposed workers with special reference to the nervous system. Scand. J. Work Environ. Health 2:152-164.
28. Knave, B., Olson, B. A., Elofsson, S., Gamberale, F., Isaksson, A., Mindus, P., Persson, H. E., Struwe, G., Wennberg, A., and Westerholm, P. 1978. Long-term exposure to jet fuel. II. A cross-sectional epidemiologic investigation on occupationally exposed industrial workers with special reference to the nervous system. Scand. J. Work Environ. Health 4:19-45.
29. Lin, B., Ritchie, G. D., Rossi J. III, and Pancrazio, J. J. 2004. Gene expression profiles in the rat central nervous system induced by JP-8 jet fuel vapor exposure. Neurosci. Lett. 363:233-238.
30. Mattie, D. R., Alden, C. L., Newell, T. K., Gaworski, C. L., and Flemming, C. D. 1991. A 90-day continuous vapor inhalation toxicity study of JP-8 jet fuel followed by 20 or 21 months of recovery in Fischer-344 rats and C57BL/6 mice. Toxicol. Pathol. 19:77-87.
31. Morrow, L. A. 1994. Cueing attention: Disruptions following organic solvent exposure. Neuropsychology 8:471-476.
32. Morrow, L. A., Robin, N. Hodgson, M. J., and Kamis, H. 1992. Assessment of attention and memory efficiency in persons with solvent neurotoxicity. Neuropsychologia 30:911-922.
33. Moser, V. C., Becking, G. C., Mac Phail, R. C, and Kulig, B. M. 1997. The IPCS collaborative study on neurobehavioral screening methods. Fundam. Appl. Toxicol. 35:143-151.
34. Moser, V. C., McCormick, J. P., Creason, J.P., and MacPhail, R. C. 1988. Comparison of chlordimeform and carbaryl using a functional observational battery. Fundam. Appl. Toxicol. 11:189-206.
35. Nordholm, A. F., Rossi J. III, Ritchie, G. D., McInturf, S., Hulme, M. E., McCool, C., Narayanan, L., MacMahon, K. L., Eggers, J., Leahy, H. F., and Wolfe, R. E. 1999. Repeated exposure of rats to JP-4 vapor induces changes in neurobehavioral capacity and 5-HT/5-HIAA levels. J. Toxicol. Environ. Health A 56:471-499.
36. Pradhan, N., and Arunasmitha, S. 1991. Correlations of motility, defecatory behavior and striatal dopaminergic activity in rats. Physiol. Behav. 50:135-138.
37. Research Advisory Committee on Gulf War Veterans' Illnesses. 2004. Scientific progress in understanding Gulf War veterans' illnesses: Report and recommendations. Washington, DC: Department of Veterans Affairs.
38. Ritchie, G. D., Still, K. R., Alexander, W. K., Nordholm, A. F., Wilson, C. L., Rossi, J. III, and Mattie, D. R. 2001. A review of the neurotoxicity risk of selected hydrocarbon fuels. J. Toxicol. Environ. Health A 64:223-312.
39. Rossi, J. III, Nordholm, A. F., Carpenter, R. L., Ritchie, G. D., and Malcomb, W. 2001. Effects of repeated exposure of rats to JP-5 or JP-8 jet fuel vapor on neurobehavioral capacity and neurotransmitter levels. J. Toxicol. Environ. Health A 63:397-428.
40. Sanberg, P. R., and Norman, A. B. 1989. Underrecognised and undersearched side effects of neuroleptics. Am. J. Psychiat. 146:411-412.
41. Sorg, B. A. 1992. Mesocorticolimbic dopamine systems: Cross-sensitization between stress and cocaine. Ann. NY Acad. Sci. 654:136-144.
42. Sorg, B., Tschirgi, M. Swindell, S., Chen, L., and Fang, A. 2001. Repeated formaldehyde effects in an animal model for multiple chemical sensitivity. Ann. NY Acad. Sci. 933:57-67.
43. Steketee, J. D., Sorg, B. A., and Kalivas, P. W. 1992. The role of the nucleus accumbens in sensitization to drugs of abuse. Prog. Neuropsychopharmacol. Biol. Psychiat. 16:237-246.
44. Struwe, G., Knave, B., and Mindus, P. 1983. Neuropsychiatric symptoms in workers occupationally exposed to jet fuel - A combined epidemiological and casuistic study. Acta Psychiat. Scand. Suppl. 303:55-67.
45. Tilson, H. A., and Moser, V. C. 1992. Comparison of screening approaches. Neurotoxicology 13:1-13.
46. U.S. Environmental Protection Agency. 1998. Neurotoxicity Screening Battery, Series 870 Health Effects Test Guidelines #870.6200.
47. Vanderschuren, L. J., and Kalivas, P. W. 2000. Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: A critical review of preclinical studies. Psychopharmacology 151:99-120.
48. Witzmann, F. A., Bauer, M. D., Fieno, A. M., Grant, R. A., Keough, T. W., Lacey, M. P., Witten, M. L., and Young, R. S. 2000. Proteomic analysis of the renal effects of simulated occupational jet fuel exposure. Electrophoresis 21:976-984.