De-phosphorylation of TRα-1 by p44/42 MAPK inhibition enhances T3-mediated GLUT5 gene expression in the intestinal cell line Caco-2 cells

Biochemical and Biophysical Research Communications

Volumn 359, Issue 4, 2007, Pages 979-984

  Mochizuki, Kazuki ^a   Sakaguchi, Naomi ^a   Takabe, Satsuki ^a   Goda, Toshinao ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Caco 2 cells; De phosphorylation; GLUT5; Thyroid hormone; TR 1

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; GLUCOSE TRANSPORTER 5; HETERODIMER; LIOTHYRONINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NUCLEAR PROTEIN; THYROID HORMONE RECEPTOR ALPHA; SLC2A5 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; INTESTINE CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; CELL STRAIN CACO 2; DRUG ANTAGONISM; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

CACO-2 CELLS; GENE EXPRESSION; GLUCOSE TRANSPORTER TYPE 5; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; SIGNAL TRANSDUCTION; THYROID HORMONE RECEPTORS ALPHA; TRIIODOTHYRONINE;

EID: 34250631995     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.06.012     Document Type: Article

References (22)

1. Hodin R.A., Meng S., and Chamberlain S.M. Thyroid hormone responsiveness is developmentally regulated in the rat small intestine: a possible role for the alpha-2 receptor variant. Endocrinology 135 (1994) 564-568
2. Koldovsky O. Response of the gastrointestinal tract to premature weaning in experimental animals. Pediatrics 75 (1985) 199-206
3. Kuranuki S., Mochizuki K., Tanaka T., and Goda T. The possible roles of homeobox protein, Cdx-2 for the expression of LPH gene during postnatal development. Life Sci. (2006)
4. Mochizuki K., Yagi E., Sakaguchi N., Mochizuki H., Takabe S., Kuranuki S., Suzuki T., Shimada M., and Goda T. The critical period for thyroid hormone responsiveness through thyroid hormone receptor isoform alpha in the postnatal small intestine. Biochim. Biophys. Acta 1770 (2007) 609-616
5. Plateroti M., Chassande O., Fraichard A., Gauthier K., Freund J.N., Samarut J., and Kedinger M. Involvement of T3Ralpha- and beta-receptor subtypes in mediation of T3 functions during postnatal murine intestinal development. Gastroenterology 116 (1999) 1367-1378
6. Matosin-Matekalo M., Mesonero J.E., Laroche T.J., Lacasa M., and Brot-Laroche E. Glucose and thyroid hormone co-regulate the expression of the intestinal fructose transporter GLUT5. Biochem. J. 339 Pt 2 (1999) 233-239
7. Gauthier R., Harnois C., Drolet J.F., Reed J.C., Vezina A., and Vachon P.H. Human intestinal epithelial cell survival: differentiation state-specific control mechanisms. Am. J. Physiol. Cell Physiol. 280 (2001) C1540-C1554
8. Plateroti M., Gauthier K., Domon-Dell C., Freund J.N., Samarut J., and Chassande O. Functional interference between thyroid hormone receptor alpha (TRalpha) and natural truncated TRDeltaalpha isoforms in the control of intestine development. Mol. Cell Biol. 21 (2001) 4761-4772
9. Fraichard A., Chassande O., Plateroti M., Roux J.P., Trouillas J., Dehay C., Legrand C., Gauthier K., Kedinger M., Malaval L., Rousset B., and Samarut J. The T3R alpha gene encoding a thyroid hormone receptor is essential for post-natal development and thyroid hormone production. EMBO J. 16 (1997) 4412-4420
10. Aranda A., and Pascual A. Nuclear hormone receptors and gene expression. Physiol. Rev. 81 (2001) 1269-1304
11. Leitman D.C., Costa C.H., Graf H., Baxter J.D., and Ribeiro R.C. Thyroid hormone activation of transcription is potentiated by activators of cAMP-dependent protein kinase. J. Biol. Chem. 271 (1996) 21950-21955
12. Tzagarakis-Foster C., and Privalsky M.L. Phosphorylation of thyroid hormone receptors by protein kinase A regulates DNA recognition by specific inhibition of receptor monomer binding. J. Biol. Chem. 273 (1998) 10926-10932
13. Davis P.J., Shih A., Lin H.Y., Martino L.J., and Davis F.B. Thyroxine promotes association of mitogen-activated protein kinase and nuclear thyroid hormone receptor (TR) and causes serine phosphorylation of TR. J. Biol. Chem. 275 (2000) 38032-38039
14. Boucher M.J., and Rivard N. Regulation and role of brush border-associated ERK1/2 in intestinal epithelial cells. Biochem. Biophys. Res. Commun. 311 (2003) 121-128
15. Aliaga J.C., Deschenes C., Beaulieu J.F., Calvo E.L., and Rivard N. Requirement of the MAP kinase cascade for cell cycle progression and differentiation of human intestinal cells. Am. J. Physiol. 277 (1999) G631-G641
16. Ding Q., Wang Q., and Evers B.M. Alterations of MAPK activities associated with intestinal cell differentiation. Biochem. Biophys. Res. Commun. 284 (2001) 282-288
17. Goda T., Yasutake H., Suzuki Y., Takase S., and Koldovsky O. Diet-induced changes in gene expression of lactase in rat jejunum. Am. J. Physiol. 268 (1995) G1066-G1073
18. Hecht A., Torbey C.F., Korsmo H.A., and Olsen W.A. Regulation of sucrase and lactase in developing rats: role of nuclear factors that bind to two gene regulatory elements. Gastroenterology 112 (1997) 803-812
19. Honma K., Mochizuki K., and Goda T. Carbohydrate/fat ratio in the diet alters histone acetylation on the sucrase-isomaltase gene and its expression in mouse small intestine. Biochem. Biophys. Res. Commun. (2007)
20. Chen S.L., Chang Y.J., Wu Y.H., and Lin K.H. Mitogen-activated protein kinases potentiate thyroid hormone receptor transcriptional activity by stabilizing its protein. Endocrinology 144 (2003) 1407-1419
21. Rochette-Egly C. Nuclear receptors: integration of multiple signalling pathways through phosphorylation. Cell Signal 15 (2003) 355-366
22. Onda K., Nagashima M., Kawakubo Y., Inoue S., Hirano T., and Oka K. Mitogen-activated protein kinase kinase 1/extracellular signal-regulated kinase (MEK-1/ERK) inhibitors sensitize reduced glucocorticoid response mediated by TNFalpha in human epidermal keratinocytes (HaCaT). Biochem. Biophys. Res. Commun. 351 (2006) 266-272