IL-10 producing CD8+ T cells in human infection with Leishmania guyanensis

Microbes and Infection

Volumn 9, Issue 8, 2007, Pages 1034-1041

  Bourreau, Eliane ^a   Ronet, Catherine ^b   Couppié, Pierre ^c   Sainte Marie, Dominique ^c   Tacchini Cottier, Fabienne ^b   Launois, Pascal ^b  

^a INSTITUT PASTEUR DE LA GUYANE   (French Guiana)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c CENTRE HOSPITALIER DE CAYENNE   (French Guiana)

Author keywords

Cytokines; Human; Parasitic protozoan; T Lymphocytes

Indexed keywords

CD45RA ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; REACTIVE NITROGEN SPECIES; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; BLOOD SAMPLING; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; LEISHMANIA; LEISHMANIASIS; LYMPHOCYTE CULTURE; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD45; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; CELLS, CULTURED; HUMANS; IMMUNOLOGIC MEMORY; INTERLEUKIN-10; LEISHMANIA GUYANENSIS; LEISHMANIASIS, MUCOCUTANEOUS; LYMPHOCYTE ACTIVATION;

LEISHMANIA GUYANENSIS; PROTOZOA;

EID: 34250631374     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2007.04.009     Document Type: Article

References (27)

1. Reiner S.L., and Locksley R.M. The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13 (1995) 151-177
2. Abbas A.K., Murphy K.M., and Sher A. Functional diversity of helper T lymphocytes. Nature 383 (1996) 787-793
3. Louzir H., Melby P.C., Ben Salah A., Marrakchi H., Aoun K., Ben Ismail R., and Dellagi K. Immunologic determinants of disease evolution in localized cutaneous leishmaniasis due to Leishmania major. J. Infect. Dis. 177 (1998) 1687-1695
4. + T cells unresponsive to IL-12. J. Infect. Dis. 183 (2001) 953-959
5. Chomarat P., and Banchereau J. Interleukin-4 and interleukin-13: their similarities and discrepancies. Int. Rev. Immunol. 17 (1998) 1-52
6. Rocha P.N., Almeida R.P., Bacellar O., de Jesus A.R., Fihlo D.C., Filho A.C., Barral A., Coffmann R.L., and Carvalho E.M. Down-regulation of Th1 type of response in early human American cutaneous leishmaniasis. J. Infect. Dis. 180 (1999) 1731-1734
7. Melby P.C., Andrade-Narvaez F., Darnell B.J., and Valencia-Pacheco G.A. In situ expression of interleukin-10 and interleukin-12 in active human cutaneous leishmaniasis. FEMS Immunol. Med. Microbiol. 15 (1996) 101-107
8. Li M.O., Wan Y.Y., Sanjabi S., Robertson A.K., and Flavell R.A. Transforming growth factor-beta regulation of immune responses. Annu. Rev. Immunol. 24 (2006) 99-146
9. Melby P.C., Andrare-Narvaez F.J., Darnell B.J., Valencia-Pacheco G., Tryon V.V., and Palomo-Ceita A. Increased expression of proinflammatory cytokines in chronic lesions of human cutaneous leishmaniasis. Infect. Immun. 62 (1994) 837-842
10. Barral A., Teixeira M., Reis P., Vinhas V., Costa J., Lessa H., Bittencourt A.L., Reed S., Carvahlo E.M., and Barral-Netto M. Transforming growth factor-beta in human cutaneous leishmaniasis. Am. J. Pathol. 147 (1995) 947-954
11. + regulatory T cells in peripheral blood mononuclear cells from healthy subjects stimulated with Leishmania guyanensis. Infect. Immun. 73 (2005) 5908-5914
12. Bacellar O., Lessa H., Schriefer A., Machado P., Ribeiro de Jesus A., Dutra W.O., Gollob K.J., and Carvahlo E.M. Up-regulation of Th1 responses in mucosal leishmaniasis patients. Infect. Immun. 70 (2002) 6734-6740
13. + T cells among human blood mononuclear cells: an early marker of exposure to Leishmania?. Scand. J. Immunol. 58 (2003) 201-210
14. Louis J.A., Moedder E., Behin R., and Engers H.D. Recognition of protozoan parasite antigens by murine T lymphocytes. Eur. J. Immunol. 9 (1979) 841-847
15. + T cells generated in response to LACK in naive subjects never exposed to Leishmania. Eur. J. Immunol. 32 (2002) 510-520
16. Green S.J., Meltzer M.S., Hibbs J.B., and Nacy C.A. Activated macrophages destroy intracellular Leishmania major amastigotes by an l-arginine dependent killing mechanism. J. Immunol. 144 (1990) 278-283
17. Mosmann T.R., and Moore K.W. The role of IL-10 in crossregulation of TH1 and TH2 responses. Immunol. Today 12 (1991) A49-A53
18. Rogers K.A., and Titus R.G. The human cytokine response to Leishmania major early after exposure to parasite in vitro. J. Parasitol. 90 (2004) 557-563
19. + T Cells in skin lesions of patients with cutaneous leishmaniasis exhibit phenotypic and functional characteristics of natural regulatory T cells. J. Infect. Dis. 193 (2006) 1313-1322
20. Antonelli L.R., Dutra W.O., Almeida R.P., Bacellar O., and Gollob K.J. Antigen specific correlations of cellular immune responses in human leishmaniasis suggests mechanisms for immunoregulation. Clin. Exp. Immunol. 136 (2004) 341-348
21. -) alpha beta and gamma delta T cells from human patients with cutaneous leishmaniasis. Infect. Immun. 74 (2006) 6317-6323
22. + type 2 T cell subsets in human leishmaniasis have distinct T cell receptor repertoires. J. Immunol. 151 (1993) 7095-7104
23. Esterre P., Dedet J.P., Frenay C., Chevallier M., and Grimaud J.A. Cell populations in the lesion of human cutaneous leishmaniasis: a light microscopical, immunohistochemical and ultrastructural study. Virchows Arch. A. Pathol. Anat. Histopathol. 421 (1992) 239-247
24. + T cells associated with cure of human cutaneous leishmaniasis. Infect. Immun. 62 (1994) 2614-2618
25. Da-Cruz A.M., Bertho A.L., Oliveira-Neto M.P., and Coutinho S.G. Flow cytometric analysis of cellular infiltrate from American tegumentary leishmaniasis lesions. Br. J. Dermatol. 153 (2005) 537-543
26. Mendonca S.C., De Luca P.M., Mayrink W., Restom T.G., Conceicao-Silva F., Da-Cruz A.M., Bertho A.L., Da Costa C.A., Genaro O., Toledo V.P., et al. Characterization of human T lymphocyte-mediated immune responses induced by a vaccine against American tegumentary leishmaniasis. Am. J. Trop. Med. Hyg. 53 (1995) 195-201
27. Belkaid Y., Hoffmann K.F., Mendez S., Kamhawi S., Udey M.C., Wynn T.A., and Sacks D.L. The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure. J. Exp. Med. 194 (2001) 1497-1506