-
1
-
-
0031985775
-
Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques
-
Matano T, Shibata R, Siemon C, et al. Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques. J Virol 1998; 72:164-169.
-
(1998)
J Virol
, vol.72
, pp. 164-169
-
-
Matano, T.1
Shibata, R.2
Siemon, C.3
-
2
-
-
0006922163
-
Decay kinetics of human immunodeficiency virus-specific effector cytotoxic T lymphocytes after combination antiretroviral therapy
-
Ogg GS, Jin X, Bonhoeffer S, et al. Decay kinetics of human immunodeficiency virus-specific effector cytotoxic T lymphocytes after combination antiretroviral therapy. J Virol 1999; 73:797-800.
-
(1999)
J Virol
, vol.73
, pp. 797-800
-
-
Ogg, G.S.1
Jin, X.2
Bonhoeffer, S.3
-
3
-
-
0030868897
-
Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease
-
Autran B, Carcelain G, Li TS, et al. Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease. Science 1997; 277:112-116.
-
(1997)
Science
, vol.277
, pp. 112-116
-
-
Autran, B.1
Carcelain, G.2
Li, T.S.3
-
4
-
-
3543125970
-
A long-term latent reservoir for HIV-1: Discovery and clinical implications
-
Siliciano JD, Siliciano RF. A long-term latent reservoir for HIV-1: discovery and clinical implications. J Antimicrob Chemother 2004; 54:6-9.
-
(2004)
J Antimicrob Chemother
, vol.54
, pp. 6-9
-
-
Siliciano, J.D.1
Siliciano, R.F.2
-
5
-
-
0037436291
-
Persistence of drug-resistant HIV-1 after a structured treatment interruption and its impact on treatment response
-
Deeks SG, Grant RM, Wrin T, et al. Persistence of drug-resistant HIV-1 after a structured treatment interruption and its impact on treatment response. AIDS 2003; 17:361-370.
-
(2003)
AIDS
, vol.17
, pp. 361-370
-
-
Deeks, S.G.1
Grant, R.M.2
Wrin, T.3
-
6
-
-
0033583977
-
Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: A cohort study
-
Carr A, Samaras K, Thorisdottir A, et al. Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: a cohort study. Lancet 1999; 353:2093-2099.
-
(1999)
Lancet
, vol.353
, pp. 2093-2099
-
-
Carr, A.1
Samaras, K.2
Thorisdottir, A.3
-
7
-
-
0036642493
-
Incidence of and risk factors for severe hepatotoxicity associated with antiretroviral combination therapy
-
Wit FW, Weverling GJ, Weel J, et al. Incidence of and risk factors for severe hepatotoxicity associated with antiretroviral combination therapy. J Infect Dis 2002; 186:23-31.
-
(2002)
J Infect Dis
, vol.186
, pp. 23-31
-
-
Wit, F.W.1
Weverling, G.J.2
Weel, J.3
-
8
-
-
18044376212
-
Lipodystrophy, metabolic disorders, and human immunodeficiency virus infection: Aquitaine Cohort, France, 1999. Groupe d'Epidemiologie Clinique du Syndrome d'Immunodeficience Acquise en Aquitaine
-
Thiebaut R, Daucourt V, Mercie P, et al. Lipodystrophy, metabolic disorders, and human immunodeficiency virus infection: Aquitaine Cohort, France, 1999. Groupe d'Epidemiologie Clinique du Syndrome d'Immunodeficience Acquise en Aquitaine. Clin Infect Dis 2000; 31:1482-1487.
-
(2000)
Clin Infect Dis
, vol.31
, pp. 1482-1487
-
-
Thiebaut, R.1
Daucourt, V.2
Mercie, P.3
-
9
-
-
0035951473
-
Lipodystrophy-associated morphological, cholesterol and triglyceride abnormalities in a population-based HIV/AIDS treatment database
-
Heath KV, Hogg RS, Chan KJ, et al. Lipodystrophy-associated morphological, cholesterol and triglyceride abnormalities in a population-based HIV/AIDS treatment database. AIDS 2001; 15:231-239.
-
(2001)
AIDS
, vol.15
, pp. 231-239
-
-
Heath, K.V.1
Hogg, R.S.2
Chan, K.J.3
-
10
-
-
0033609174
-
Control of HIV despite the discontinuation of antiretroviral therapy
-
Lisziewicz J, Rosenberg E, Lieberman J, et al. Control of HIV despite the discontinuation of antiretroviral therapy. N Engl J Med 1999; 340:1683-1684.
-
(1999)
N Engl J Med
, vol.340
, pp. 1683-1684
-
-
Lisziewicz, J.1
Rosenberg, E.2
Lieberman, J.3
-
11
-
-
0032719664
-
HIV-1-specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy
-
Ortiz GM, Nixon DF, Trkola A, et al. HIV-1-specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy. J Clin Invest 1999; 104:R13-R18.
-
(1999)
J Clin Invest
, vol.104
-
-
Ortiz, G.M.1
Nixon, D.F.2
Trkola, A.3
-
12
-
-
33846024773
-
-
Pai NP, Lawrence J, Reingold AL, et al. Structured treatment interruptions (STI) in chronic unsuppressed HIV infection in adults. Cochrane Database Syst Rev 2006; 3:CD006148. A rigorous review of trials exploring treatment interruption in chronic unsuppressed HIV-infected adults.
-
Pai NP, Lawrence J, Reingold AL, et al. Structured treatment interruptions (STI) in chronic unsuppressed HIV infection in adults. Cochrane Database Syst Rev 2006; 3:CD006148. A rigorous review of trials exploring treatment interruption in chronic unsuppressed HIV-infected adults.
-
-
-
-
13
-
-
33644874549
-
-
Pai NP, Tulsky JP, Lawrence J, et al. Structured treatment interruptions (STI) in chronic suppressed HIV infection in adults. Cochrane Database Syst Rev 2005; 4:CD005482. A rigorous review of trials exploring treatment interruption in chronically infected, HIV-suppressed adults.
-
Pai NP, Tulsky JP, Lawrence J, et al. Structured treatment interruptions (STI) in chronic suppressed HIV infection in adults. Cochrane Database Syst Rev 2005; 4:CD005482. A rigorous review of trials exploring treatment interruption in chronically infected, HIV-suppressed adults.
-
-
-
-
14
-
-
34250680405
-
-
Collins S. SMART study halted due to safety concerns with significantly more AIDS events in the treatment interruption arm. HTB 2006; 7:34-35.
-
Collins S. SMART study halted due to safety concerns with significantly more AIDS events in the treatment interruption arm. HTB 2006; 7:34-35.
-
-
-
-
15
-
-
23344437796
-
Retrospective analysis of suspending HAART in selected patients with controlled HIV replication
-
Jacobs B, Neil N, Aboulafia DM. Retrospective analysis of suspending HAART in selected patients with controlled HIV replication. AIDS Patient Care STD 2005; 19:429-438.
-
(2005)
AIDS Patient Care STD
, vol.19
, pp. 429-438
-
-
Jacobs, B.1
Neil, N.2
Aboulafia, D.M.3
-
16
-
-
25144473488
-
-
Mata RC, Viciana P, de Alarcon A, et al. Discontinuation of antiretroviral therapy in patients with chronic HIV infection: clinical, virologic, and immunologic consequences. AIDS Patient Care STD 2005; 19:550-562. This study showed that individuals who were able to continue treatment interruption had higher CD4 T-cell nadirs.
-
Mata RC, Viciana P, de Alarcon A, et al. Discontinuation of antiretroviral therapy in patients with chronic HIV infection: clinical, virologic, and immunologic consequences. AIDS Patient Care STD 2005; 19:550-562. This study showed that individuals who were able to continue treatment interruption had higher CD4 T-cell nadirs.
-
-
-
-
17
-
-
33646817438
-
Safe treatment interruptions in patients with nadir CD4 counts of more than 350 cells/microl: A randomized trial
-
Krolewiecki AJ, Zala C, Vanzulli C, et al. Safe treatment interruptions in patients with nadir CD4 counts of more than 350 cells/microl: a randomized trial. J Acquir Immune Defic Syndr 2006; 41:425-429.
-
(2006)
J Acquir Immune Defic Syndr
, vol.41
, pp. 425-429
-
-
Krolewiecki, A.J.1
Zala, C.2
Vanzulli, C.3
-
18
-
-
24644469032
-
-
Pellegrin I, Thiebaut R, Blanco P, et al. Can highly active antiretroviral therapy be interrupted in patients with sustained moderate HIV RNA and >400 CD4+ cells/microl? Impact on immunovirological parameters. J Med Virol 2005; 77:164-172. This study highlights the fact that the only immunovirological parameter that predicts the success of treatment interruption is CD4 T-cell nadir.
-
Pellegrin I, Thiebaut R, Blanco P, et al. Can highly active antiretroviral therapy be interrupted in patients with sustained moderate HIV RNA and >400 CD4+ cells/microl? Impact on immunovirological parameters. J Med Virol 2005; 77:164-172. This study highlights the fact that the only immunovirological parameter that predicts the success of treatment interruption is CD4 T-cell nadir.
-
-
-
-
19
-
-
33745003258
-
-
Danel C, Moh R, Minga A, et al. CD4-guided structured antiretroviral treatment interruption strategy in HIV-infected adults in west Africa (Trivacan ANRS 1269 trial): a randomised trial. Lancet 2006; 367:1981-1989. This study looked at CD4 T-cell-guided treatment interruption, and showed that patients on CD4 T-cell-guided treatment interruption had a 2.5-fold increase in the severe morbidity rate compared with patients on continuous therapy.
-
Danel C, Moh R, Minga A, et al. CD4-guided structured antiretroviral treatment interruption strategy in HIV-infected adults in west Africa (Trivacan ANRS 1269 trial): a randomised trial. Lancet 2006; 367:1981-1989. This study looked at CD4 T-cell-guided treatment interruption, and showed that patients on CD4 T-cell-guided treatment interruption had a 2.5-fold increase in the severe morbidity rate compared with patients on continuous therapy.
-
-
-
-
20
-
-
33746479812
-
CD4-guided scheduled treatment interruptions compared with continuous therapy for patients infected with HIV-1: Results of the Staccato randomised trial
-
Ananworanich J, Gayet-Ageron A, Le Braz M, et al. CD4-guided scheduled treatment interruptions compared with continuous therapy for patients infected with HIV-1: results of the Staccato randomised trial. Lancet 2006; 368:459-465.
-
(2006)
Lancet
, vol.368
, pp. 459-465
-
-
Ananworanich, J.1
Gayet-Ageron, A.2
Le Braz, M.3
-
21
-
-
23244437092
-
Highly active antiretroviral therapy (HAART) retreatment in patients on CD4-guided therapy achieved similar virologic suppression compared with patients on continuous HAART: The HIV Netherlands Australia Thailand Research Collaboration 001.4 study
-
Ananworanich J, Siangphoe U, Hill A, et al. Highly active antiretroviral therapy (HAART) retreatment in patients on CD4-guided therapy achieved similar virologic suppression compared with patients on continuous HAART: the HIV Netherlands Australia Thailand Research Collaboration 001.4 study. J Acquir Immune Defic Syndr 2005; 39:523-529.
-
(2005)
J Acquir Immune Defic Syndr
, vol.39
, pp. 523-529
-
-
Ananworanich, J.1
Siangphoe, U.2
Hill, A.3
-
22
-
-
13944262121
-
A prospective, randomized trial of structured treatment interruption for patients with chronic HIV type 1 infection
-
Cardiello PG, Hassink E, Ananworanich J, et al. A prospective, randomized trial of structured treatment interruption for patients with chronic HIV type 1 infection. Clin Infect Dis 2005; 40:594-600.
-
(2005)
Clin Infect Dis
, vol.40
, pp. 594-600
-
-
Cardiello, P.G.1
Hassink, E.2
Ananworanich, J.3
-
23
-
-
10744229013
-
Failures of 1 week on, 1 week off antiretroviral therapies in a randomized trial
-
Ananworanich J, Nuesch R, Le Braz M, et al. Failures of 1 week on, 1 week off antiretroviral therapies in a randomized trial. AIDS 2003; 17:F33-F37.
-
(2003)
AIDS
, vol.17
-
-
Ananworanich, J.1
Nuesch, R.2
Le Braz, M.3
-
24
-
-
15744397757
-
Randomized, controlled trial of therapy interruption in chronic HIV-1 infection
-
Papasavvas E, Kostman JR, Mounzer K, et al. Randomized, controlled trial of therapy interruption in chronic HIV-1 infection. PLoS Med 2004; 1:e64.
-
(2004)
PLoS Med
, vol.1
-
-
Papasavvas, E.1
Kostman, J.R.2
Mounzer, K.3
-
25
-
-
33749022485
-
Reactivation of ancestral strains of HIV-1 in the gp120 V3 env region in patients failing antiretroviral therapy and subjected to structured treatment interruption
-
Silva WP, Santos DE, Leal E, et al. Reactivation of ancestral strains of HIV-1 in the gp120 V3 env region in patients failing antiretroviral therapy and subjected to structured treatment interruption. Virology 2006; 354:35-47.
-
(2006)
Virology
, vol.354
, pp. 35-47
-
-
Silva, W.P.1
Santos, D.E.2
Leal, E.3
-
26
-
-
25844439955
-
Virological and pharmacological factors associated with virological response to salvage therapy after an 8-week of treatment interruption in a context of very advanced HIV disease (GigHAART ANRS 097)
-
Delaugerre C, Peytavin G, Dominguez S, et al. Virological and pharmacological factors associated with virological response to salvage therapy after an 8-week of treatment interruption in a context of very advanced HIV disease (GigHAART ANRS 097). J Med Virol 2005; 77:345-350.
-
(2005)
J Med Virol
, vol.77
, pp. 345-350
-
-
Delaugerre, C.1
Peytavin, G.2
Dominguez, S.3
-
27
-
-
27144521249
-
No benefit of a structured treatment interruption based on genotypic resistance in heavily pretreated HIV-infected patients
-
Ghosn J, Wirden M, Ktorza N, et al. No benefit of a structured treatment interruption based on genotypic resistance in heavily pretreated HIV-infected patients. AIDS 2005; 19:1643-1647.
-
(2005)
AIDS
, vol.19
, pp. 1643-1647
-
-
Ghosn, J.1
Wirden, M.2
Ktorza, N.3
-
28
-
-
10744223335
-
Benefit of treatment interruption in HIV-infected patients with multiple therapeutic failures: A randomized controlled trial (ANRS 097)
-
Katlama C, Dominguez S, Gourlain K, et al. Benefit of treatment interruption in HIV-infected patients with multiple therapeutic failures: a randomized controlled trial (ANRS 097). AIDS 2004; 18:217-226.
-
(2004)
AIDS
, vol.18
, pp. 217-226
-
-
Katlama, C.1
Dominguez, S.2
Gourlain, K.3
-
29
-
-
0042431969
-
Structured treatment interruption in patients with multidrug-resistant human immunodeficiency virus
-
Lawrence J, Mayers DL, Hullsiek KH, et al. Structured treatment interruption in patients with multidrug-resistant human immunodeficiency virus. N Engl J Med 2003; 349:837-846.
-
(2003)
N Engl J Med
, vol.349
, pp. 837-846
-
-
Lawrence, J.1
Mayers, D.L.2
Hullsiek, K.H.3
-
30
-
-
0142074332
-
Role of structured treatment interruption before a 5-drug salvage antiretroviral regimen: The Retrogene Study
-
Ruiz L, Ribera E, Bonjoch A, et al. Role of structured treatment interruption before a 5-drug salvage antiretroviral regimen: the Retrogene Study. J Infect Dis 2003; 188:977-985.
-
(2003)
J Infect Dis
, vol.188
, pp. 977-985
-
-
Ruiz, L.1
Ribera, E.2
Bonjoch, A.3
-
31
-
-
0029880783
-
Cytotoxic T lymphocytes in asymptomatic long-term nonprogressing HIV-1 infection: Breadth and specificity of the response and relation to in vivo viral quasispecies in a person with prolonged infection and low viral load
-
Harrer T, Harrer E, Kalams SA, et al. Cytotoxic T lymphocytes in asymptomatic long-term nonprogressing HIV-1 infection: breadth and specificity of the response and relation to in vivo viral quasispecies in a person with prolonged infection and low viral load. J Immunol 1996; 156:2616-2623.
-
(1996)
J Immunol
, vol.156
, pp. 2616-2623
-
-
Harrer, T.1
Harrer, E.2
Kalams, S.A.3
-
32
-
-
2342591920
-
Immunologic and virologic evolution during periods of intermittent and persistent low-level viremia
-
Karlsson AC, Younger SR, Martin JN, et al. Immunologic and virologic evolution during periods of intermittent and persistent low-level viremia. AIDS 2004; 18:981-989.
-
(2004)
AIDS
, vol.18
, pp. 981-989
-
-
Karlsson, A.C.1
Younger, S.R.2
Martin, J.N.3
-
33
-
-
30944442077
-
HIV-1-specific CD4+ T cell responses in chronically HIV-1 infected blippers on antiretroviral therapy in relation to viral replication following treatment interruption
-
Papasavvas E, Kostman JR, Thiel B, et al. HIV-1-specific CD4+ T cell responses in chronically HIV-1 infected blippers on antiretroviral therapy in relation to viral replication following treatment interruption. J Clin Immunol 2006; 26:40-54.
-
(2006)
J Clin Immunol
, vol.26
, pp. 40-54
-
-
Papasavvas, E.1
Kostman, J.R.2
Thiel, B.3
-
34
-
-
33646190052
-
HIV-specific cellular immune responses are stimulated by structured treatment interruption in chronically HIV-1 infected Koreans
-
Choi JY, Song YG, Park YS, et al. HIV-specific cellular immune responses are stimulated by structured treatment interruption in chronically HIV-1 infected Koreans. Yonsei Med J 2006; 47:282-286.
-
(2006)
Yonsei Med J
, vol.47
, pp. 282-286
-
-
Choi, J.Y.1
Song, Y.G.2
Park, Y.S.3
-
35
-
-
33745949890
-
Dynamics of T cells subsets and lymphoproliferative responses during structured treatment interruption cycles and after definitive interruption of HAART in early chronic HIV type-1-infected patients
-
This study showed that the exposure and level of antigen could influence T-cell maturation, potentially overwhelming the immune response
-
Libois A, Lopez A, Garcia F, et al. Dynamics of T cells subsets and lymphoproliferative responses during structured treatment interruption cycles and after definitive interruption of HAART in early chronic HIV type-1-infected patients. AIDS Res Hum Retroviruses 2006; 22:657-666. This study showed that the exposure and level of antigen could influence T-cell maturation, potentially overwhelming the immune response.
-
(2006)
AIDS Res Hum Retroviruses
, vol.22
, pp. 657-666
-
-
Libois, A.1
Lopez, A.2
Garcia, F.3
-
37
-
-
0036197625
-
Expansion of preexisting, lymph node-localized CD8+ T cells during supervised treatment interruptions in chronic HIV-1 infection
-
Altfeld M, van Lunzen J, Frahm N, et al. Expansion of preexisting, lymph node-localized CD8+ T cells during supervised treatment interruptions in chronic HIV-1 infection. J Clin Invest 2002; 109:837-843.
-
(2002)
J Clin Invest
, vol.109
, pp. 837-843
-
-
Altfeld, M.1
van Lunzen, J.2
Frahm, N.3
-
38
-
-
27144527399
-
Effect of treatment interruption monitored by CD4 cell count on mitochondrial DNA content in HIV-infected patients: A prospective study
-
Mussini C, Pinti M, Bugarini R, et al. Effect of treatment interruption monitored by CD4 cell count on mitochondrial DNA content in HIV-infected patients: a prospective study. AIDS 2005; 19:1627-1633.
-
(2005)
AIDS
, vol.19
, pp. 1627-1633
-
-
Mussini, C.1
Pinti, M.2
Bugarini, R.3
-
39
-
-
20144379418
-
Development of HIV with drug resistance after CD4 cell count-guided structured treatment interruptions in patients treated with highly active antiretroviral therapy after dual-nucleoside analogue treatment
-
Nuesch R, Ananworanich J, Sirivichayakul S, et al. Development of HIV with drug resistance after CD4 cell count-guided structured treatment interruptions in patients treated with highly active antiretroviral therapy after dual-nucleoside analogue treatment. Clin Infect Dis 2005; 40:728-734.
-
(2005)
Clin Infect Dis
, vol.40
, pp. 728-734
-
-
Nuesch, R.1
Ananworanich, J.2
Sirivichayakul, S.3
-
40
-
-
33745102005
-
3 after treatment interruption following antiretroviral therapy +/- interleukin 2: Results of ACTG A5102
-
3 after treatment interruption following antiretroviral therapy +/- interleukin 2: results of ACTG A5102. J Acquir Immune Defic Syndr 2006; 42:140-148.
-
(2006)
J Acquir Immune Defic Syndr
, vol.42
, pp. 140-148
-
-
Henry, K.1
Katzenstein, D.2
Cherng, D.W.3
-
41
-
-
33645030627
-
Sustained control of viremia following therapeutic immunization in chronically HIV-1-infected individuals
-
Levy Y, Durier C, Lascaux AS, et al. Sustained control of viremia following therapeutic immunization in chronically HIV-1-infected individuals. AIDS 2006; 20:405-413.
-
(2006)
AIDS
, vol.20
, pp. 405-413
-
-
Levy, Y.1
Durier, C.2
Lascaux, A.S.3
-
42
-
-
33646480371
-
Peptide-loaded dendritic-cell vaccination followed by treatment interruption for chronic HIV-1 infection: A phase 1 trial
-
Ide F, Nakamura T, Tomizawa M, et al. Peptide-loaded dendritic-cell vaccination followed by treatment interruption for chronic HIV-1 infection: a phase 1 trial. J Med Virol 2006; 78:711-718.
-
(2006)
J Med Virol
, vol.78
, pp. 711-718
-
-
Ide, F.1
Nakamura, T.2
Tomizawa, M.3
-
43
-
-
20844456226
-
Therapeutic immunization with dendritic cells loaded with heat-inactivated autologous HIV-1 in patients with chronic HIV-1 infection
-
Garcia F, Lejeune M, Climent N, et al. Therapeutic immunization with dendritic cells loaded with heat-inactivated autologous HIV-1 in patients with chronic HIV-1 infection. J Infect Dis 2005; 191:1680-1685.
-
(2005)
J Infect Dis
, vol.191
, pp. 1680-1685
-
-
Garcia, F.1
Lejeune, M.2
Climent, N.3
-
44
-
-
20944446452
-
Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies
-
Trkola A, Kuster H, Rusert P, et al. Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies. Nat Med 2005; 11:615-622.
-
(2005)
Nat Med
, vol.11
, pp. 615-622
-
-
Trkola, A.1
Kuster, H.2
Rusert, P.3
-
45
-
-
33645096222
-
Partial treatment interruption of protease inhibitor-based highly active antiretroviral therapy regimens in HIV-infected children
-
This study describes the effects of therapy simplification by partial therapy interruption in children
-
Abadi J, Sprecher E, Rosenberg MG, et al. Partial treatment interruption of protease inhibitor-based highly active antiretroviral therapy regimens in HIV-infected children. J Acquir Immune Defic Syndr 2006; 41:298-303. This study describes the effects of therapy simplification by partial therapy interruption in children.
-
(2006)
J Acquir Immune Defic Syndr
, vol.41
, pp. 298-303
-
-
Abadi, J.1
Sprecher, E.2
Rosenberg, M.G.3
-
46
-
-
27144433671
-
-
Legrand FA, Abadi J, Jordan KA, et al. Partial treatment interruption of protease inhibitors augments HIV-specific immune responses in vertically infected pediatric patients. AIDS 2005; 19:1575-1585. This study reports that HIV-specific cellular responses are increased in children who received partial treatment interruption.
-
Legrand FA, Abadi J, Jordan KA, et al. Partial treatment interruption of protease inhibitors augments HIV-specific immune responses in vertically infected pediatric patients. AIDS 2005; 19:1575-1585. This study reports that HIV-specific cellular responses are increased in children who received partial treatment interruption.
-
-
-
|