Analysis of dioxins in contaminated soils with the calux and caflux bioassays, an immunoassay, and gas chromatography/high-resolution mass spectrometry

Environmental Toxicology and Chemistry

Volumn 26, Issue 6, 2007, Pages 1122-1129

  Nording, Malin ^a,b   Denison, Michael S ^c   Baston, David ^c   Persson, Ylva ^a   Spinnel, Erik ^a   Haglund, Peter ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b SWEDISH DEFENCE RESEARCH AGENCY   (Sweden)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CAFLUX; CALUX; Dioxin; Enzyme linked immunosorbent assay; Soil

Indexed keywords

BIOASSAY; ENVIRONMENTAL PROTECTION AGENCY; FURAN RESINS; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; ORGANIC POLLUTANTS; SOIL POLLUTION;

CAFLUX; CALUX; DIOXIN; ENZYME-LINKED IMMUNOSORBENT ASSAY;

TOXIC MATERIALS;

POLYCHLORINATED DIBENZODIOXIN; POLYCHLORINATED DIBENZOFURAN;

ANALYTICAL METHOD; BIOASSAY; DIOXIN; IMMUNOASSAY; MASS SPECTROMETRY; PCDD; PCDF; PERFORMANCE ASSESSMENT; SOIL POLLUTION; SOIL REMEDIATION;

ARTICLE; BIOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; GAS CHROMATOGRAPHY; IMMUNOASSAY; MASS SPECTROMETRY; PRIORITY JOURNAL; PURIFICATION; SOIL ANALYSIS; SOIL MANAGEMENT; SOIL POLLUTION;

BIOLOGICAL ASSAY; DIOXINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; SOIL POLLUTANTS;

EID: 34250615588     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/06-458R.1     Document Type: Article

References (38)

1. Harris MW, Moore JA, Vos JG, Gupta BN. 1973. General biological effects of TCDD [2,3,7,8-tetrachlorodibenzo-p-dioxin] in laboratory animals. Environ Health Perspect 5:101-109.
2. Safe SH. 1986. Comparative toxicology and mechanism of action of polychlorinated-p-dioxins and dibenzofurans. Annu Rev Pharmacol Toxicol 26:371-399.
3. Bernes C. 1998. Persistent organic pollutants: A Swedish view of an international problem. Monitor 16. Swedish Environmental Protection Agency, Stockholm, Sweden.
4. Denison MS, Pandini A, Nagy SR, Baldwin EP, Bonati L. 2002. Ligand binding and activation of the Ah receptor. Chem-Biol Interact 141:3-24.
5. Denison MS, Nagy SR. 2003. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu Rev Pharmacol Toxicol 43:309-334.
6. Denison MS, Heath-Pagliuso S. 1998. The Ah receptor: A regulator of the biochemical and toxicological actions of structurally diverse chemicals. Bull Environ Contam Toxicol 61:557-568.
7. Van den Berg M, Birnbaum L, Bosveld ATC, Brunström B, Cook P, Feeley M, Giesy JP, Hanberg A, Hasegawa R, Kennedy SW, Kubiak T, Larsen JC, van Leeuwen FXR, Liem AKD, Nolt C, Peterson RE, Poellinger L, Safe S, Schrenk D, Tillitt D, Tysklind M, Younes M, Wærn F, Zacharewski T. 1998. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife. Environ Health Perspect 106:775-792.
8. Van den Berg M, Birnbaum L, Denison M, De Vito M, Farland W, Feeley M, Fiedler H, Hakansson H, Hanberg A, Haws L, Rose M, Safe S, Schrenk D, Tohyama C, Tritscher A, Tuomisto J, Tysklind M, Walker N, Peterson RE. 2006. The 2005 world health organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol Sci 93:223-241.
9. Behnisch PA, Hosoe K, Sakai S. 2001. Bioanalytical screening methods for dioxins and dioxin-like compounds - A review of bioassay/biomarker technology. Environ Int 27:413-439.
10. Denison MS, Zhao B, Baston DS, Clark GC, Murata H, Han D. 2004. Recombinant cell bioassay systems for the detection and relative quantitation of halogenated dioxins and related chemicals. Talanta 63:1123-1133.
11. Whyte JJ, Schmitt CJ, Tillitt DE. 2004. The H4IIE cell bioassay as an indicator of dioxin-like chemicals in wildlife and the environment. Crit Rev Toxicol 34:1-83.
12. Denison MS, Seidel SD, Ziccardi M, Rogers WJ, Brown D, Clark G. 1999. Ah receptor-based bioassays for dioxins and related chemicals: Applications and limitations. Organohalogen Compd 40:27-30.
13. Murk AJ, Legler J, Denison MS, Giesy JP, Van de Guchte C, Brouwer A. 1996. Chemical-activated luciferase gene expression (CALUX): A novel in vitro bioassay for Ah receptor active compounds in sediments and pore water. Fundam Appl Toxicol 33: 149-160.
14. Murk AJ, Leonards PEG, Bulder AS, Jonas AS, Rozemeijer MJC, Denison MS, Koeman JH, Brouwer A. 1997. The CALUX (chemical-activated luciferase expression) assay adapted and validated for measuring TCDD equivalents in blood plasma. Environ Toxicol Chem 16:1583-1589.
15. Engwall M, Brunström B, Näf C, Hjelm K. 1999. Levels of dioxin-like compounds in sewage sludge determined with a bioassay based on EROD induction in chicken embryo liver cultures. Chemosphere 38:2327-2343.
16. Scippo ML, Eppe G, De Pauw E, Maghuin-Rogister G. 2004. DR-CALUX® screening of food samples: Evaluation of the quantitative approach to measure dioxin, furans and dioxin-like PCBs. Talanta 63:1193-1202.
17. Ziccardi MH, Gardner IA, Denison MS. 2002. Application of the luciferase recombinant cell culture bioassay system for the analysis of polycyclic aromatic hydrocarbons. Environ Toxicol Chem 21:2027-2033.
18. Behnisch PA, Hosoe K, Brouwer A, Sakai S. 2002. Screening of dioxin-like toxicity equivalents for various matrices with wildtype and recombinant rat hepatoma H4IIE cells. Toxicol Sci 69:125-130.
19. Besselink HT, Schipper C, Klamer H, Leonards P, Verhaar H, Felzel E, Murk AJ, Thain J, Hosoe K, Schoetter G, Legler J, Brouwer B. 2004. Intra- and interlaboratory calibration of the DR CALUX® bioassay for the analysis of dioxins and dioxin-like chemicals in sediments. Environ Toxicol Chem 23:2781-2789.
20. Behnisch PA, Hosoe K, Sakai S. 2001. Combinatorial bio/chemical analysis of dioxin and dioxin-like compounds in waste recycling, feed/food, humans/wildlife and the environment. Environ Int 27:495-519.
21. Li W, Wu WZ, Barbara RB, Schramm KW, Kettrup A. 1999. A new enzyme immunoassay for PCDD/F TEQ screening in environmental samples: Comparison to micro-EROD assay and to chemical analysis. Chemosphere 38:3313-3318.
22. Roy S, Mysior P, Brzezinski R. 2002. Comparison of dioxin and furan TEQ determination in contaminated soil using chemical, micro-EROD, and immunoassay analysis. Chemosphere 48:833-842.
23. Garrison PM, Tullis K, Aarts JMMJG, Brouwer A, Giesy JP, Denison MS. 1996. Species-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals. Fundam Appl Toxicol 30:194-203.
24. Nagy SR, Sanborn JR, Hammock BD, Denison MS. 2002. Development of a green fluorescent protein-based cell bioassay for the rapid and inexpensive detection and characterization of Ah receptor agonists. Toxicol Sci 65:200-210.
25. Nagy SR, Liu G, Lam KS, Denison MS. 2002. Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay. Biochemistry 41: 861-868.
26. Han D, Nagy SR, Denison MS. 2004. Comparison of recombinant cell bioassays for the detection of Ah receptor agonists. Bio-Factors 20:11-22.
27. Windal I, Denison MS, Birnbaum LS, Van Wouwe N, Baeyens W, Goeyens L. 2005. Chemically activated luciferase gene expression (CALUX) cell bioassay analysis for the estimation of dioxin-like activity: Critical parameters of the CALUX procedure that impact assay results. Environ Sci Technol 39:7357-7364.
28. Nording M, Nichkova M, Spinnel E, Persson Y, Gee SJ, Hammock BD, Haglund P. 2006. Rapid screening of dioxin-contaminated soil by accelerated solvent extraction/purification followed by immunochemical detection. Anal Bioanal Chem 385:357-366.
29. U.S. Environmental Protection Agency. 1994. Tetra- through octa-chlorinated dioxins and furans by isotope dilution HRGC/ HRMS. EPA Method 1613. EPA 821-B-94-005. Washington, DC.
30. European Committee for Standardization. 1997. Stationary source emissions - Determination of the mass concentration of PCDDs/ PCDFs. EN 1948:2-3, Brussels, Belgium.
31. Liljelind P, Söderström G, Hedman B, Karlsson S, Lundin L, Marklund S. 2003. Method for multiresidue determination of halogenated aromatics and PAHs in combustion-related samples. Environ Sci Technol 37:3680-3686.
32. Ziccardi MH, Gardner IA, Denison MS. 2000. Development and modification of a recombinant cell bioassay to directly detect halogenated and polycyclic aromatic hydrocarbons in serum. Toxicol Sci 54:183-193.
33. Fields TJ. 1998. Directive from the EPA office of solid waste and emergency response. Directive 9200.4-26. U.S. Environmental Protection Agency, Washington, DC.
34. Villeneuve DL, Blankenship AL, Giesy JP. 2000. Derivation and application of relative potency estimates based on in vitro bioassay results. Environ Toxicol Chem 19:2835-2843.
35. Denison MS, Seidel SD, Rogers WJ, Ziccardi M, Winter GM, Heath-Pagliuso S. 1999. Natural and synthetic ligands for the Ah receptor. In Puga A, Wallace KB, eds, Molecular Biology Approaches to Toxicology. Taylor and Francis, Philadelphia, PA, USA, pp 393-410.
36. Koistinen J, Sanderson JT, Giesy JP. 1996. Ethoxyresorufin-O-deethylase induction potency of polychlorinated diphenyl ethers in H4IIE rat hepatoma cells. Environ Toxicol Chem 15:2028-2034.
37. Aarts JMMJG, Denison MS, Cox MA, Schalk MAC, Garrison PM, Tullis K, de Haan LHJ, Brouwer A. 1995. Species-specific antagonism of Ah receptor action by 2,2′,5,5′-tetrachloro and 2,2′,3,3′,4,4′- hexachlorobiphenyl. Eur J Pharmacol 293:463-474.
38. Nording M, Sporring S, Wiberg K, Björklund E, Haglund P. 2005. Monitoring dioxins in food and feedstuffs using accelerated solvent extraction with a novel integrated carbon fractionation cell in combination with a CAFLUX bioassay. Anal Bioanal Chem 381:1472-1475.