Optimal metabolite curve fitting for kinetic modeling of 11C-WAY-100635

Journal of Nuclear Medicine

Volumn 48, Issue 6, 2007, Pages 926-931

  Wu, Songmei ^a   Ogden, R Todd ^b,c,d   Mann, J John ^c,d   Parsey, Ramin V ^c,d  

^a NEW YORK CITY DEPARTMENT OF HEALTH AND MENTAL HYGIENE   (United States)

^b Howard Hughes Medical Institute   (United States)

^c Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

^d NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

Kinetic modeling; Nonlinear modeling; Residual analysis

Indexed keywords

CARBON 11; DRUG METABOLITE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE C 11; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG METABOLISM; HUMAN; MAJOR CLINICAL STUDY; MATHEMATICAL MODEL; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

BRAIN; CARBON RADIOISOTOPES; HUMANS; MODELS, BIOLOGICAL; NONLINEAR DYNAMICS; PIPERAZINES; POSITRON-EMISSION TOMOGRAPHY; PYRIDINES; RADIOPHARMACEUTICALS; RECEPTOR, SEROTONIN, 5-HT1A; SEROTONIN ANTAGONISTS;

EID: 34250363918     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.106.038075     Document Type: Article

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