High-quality oligo-RNA synthesis using the new 2′-O-TEM protecting group by selectively quenching the addition of p-tolyl vinyl sulphone to exocyclic amino functions

Canadian Journal of Chemistry

Volumn 85, Issue 4, 2007, Pages 293-301

  Zhou, Chuanzheng ^a   Pathmasiri, Wimal ^a   Honcharenko, Dmytro ^a   Chatterjee, Subhrangsu ^a   Barman, Jharna ^a   Chattopadhyaya, Jyoti ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Michael addition; p tolyl vinyl sulphone; RNA alkylation; RNA synthesis

Indexed keywords

ADDITION REACTIONS; ALKYLATION; OLIGOMERS; SPECTROSCOPIC ANALYSIS; SYNTHESIS (CHEMICAL); TRANSMISSION ELECTRON MICROSCOPY;

MICHAEL ADDITION; P-TOLYL VINYL SULPHONE; RNA ALKYLATION; RNA SYNTHESIS;

RNA;

EID: 34250358682     PISSN: 00084042     EISSN: None     Source Type: Journal    
DOI: 10.1139/V07-025     Document Type: Article

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