Effect of polaprezinc on taste disorders in zinc-deficient rats

BioFactors

Volumn 28, Issue 3-4, 2006, Pages 185-193

  Hamano, Hiroki ^a   Yoshinaga, Koji ^a   Eta, Runa ^a   Emori, Yutaka ^a   Kawasaki, Daisuke ^a   Iino, Yuka ^a   Sawada, Miwa ^a   Kuroda, Hiroyuki ^a   Takei, Mineo ^a  

^a ZERIA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Rat; Taste bud cell proliferation; Taste disorder; Two bottle preference test; Z 103; Zinc

Indexed keywords

BROXURIDINE; POLAPREZINC; QUININE; SODIUM CHLORIDE; ZINC; CARNOSINE; DRUG DERIVATIVE; ORGANOMETALLIC COMPOUND; ZINC DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BITTER TASTE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFECT; FEEDING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE; TASTE BUD; TASTE DISORDER; TASTE PREFERENCE; ZINC BLOOD LEVEL; ZINC DEFICIENCY; ANIMAL; BLOOD; CYTOLOGY; METABOLISM; SPRAGUE DAWLEY RAT; TASTE; WISTAR RAT;

RATTUS;

ANIMALS; BROMODEOXYURIDINE; CARNOSINE; CELL PROLIFERATION; MALE; ORGANOMETALLIC COMPOUNDS; QUININE; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; SODIUM CHLORIDE; TASTE; TASTE BUDS; TASTE DISORDERS; ZINC; ZINC COMPOUNDS;

EID: 34250347293     PISSN: 09516433     EISSN: None     Source Type: Journal    
DOI: 10.1002/biof.5520280305     Document Type: Article

References (19)

1. L.M. Beidler and R.L. Smallman, Renewal of cells within taste buds, J Cell Biol 27 (1965), 263-272.
2. F.A. Catalanotto and P. Lacy, Effects of a zinc deficient diet upon fluid intake in the rat, J Nutr 107 (1977), 436-442.
3. J. Chandrashekar, K.L. Muller, M.A. Hoon, E. Adler, L. Feng, W. Guo, C.S. Zuker and N.J.P. Ryba, T2Rs function as bitter taste receptors, Cell 100 (2000), 703-711.
4. A.N. Epstein and E. Stellar, The control of salt preference in the adrenalectomized rat, J Comp Physiol Psychol 48 (1955), 167-172.
5. T. Goto, M. Komai, H. Suzuki and Y. Furukawa, Long-term zinc deficiency decreases taste sensitivity in rats, J Nutr 131 (2001), 305-310.
6. T. Goto, M. Komai, B.P. Bryant and Y. Furukawa, Reduction in carbonic anhydrase activity in the tongue epithelium and submandibular gland in zinc-deficient rats, Int J Vitam Nutr Res 70 (2000), 110-118.
7. H.G. Gratzner, Monoclonal antibody to 5-bromo-and 5-iododeoxy-uridine: a new reagent for detection of DNA replication, Science 218 (1982), 474-476.
8. S.M. Heckmann, P. Hujoel, S. Habiger, W. Friess, M. Wichmann, J.G. Heckmann and T. Hummel, Zinc gluconate in the treatment of dysgeusia - a randomized clinical trial, J Dent Res 84 (2005), 35-38.
9. ++, Life Sci 9 (1970), 701-709.
10. M. Hirota, T. Ito, K. Okudela, R. Kawabe, H. Hayashi, T, Yazawa, K. Fujita and H. Kitamura, Expression of cyclin-dependent kinase inhibitors in taste buds of mouse and hamster, Tissue Cell 33 (2001), 25-32.
11. W. Jakinovich, Jr. and D.W. Osborn, Zinc nutrition and salt preference in rats, Am J Physiol 241 (1981), R233-R239.
12. M. Komai, T. Goto, H. Suzuki, T. Takeda and Y. Furukawa, Zinc deficiency and taste dysfunction; contribution of carbonic anhydrase, a zinc-metalloenzyme, to normal taste sensation, Biofactors 12 (2000), 65-70.
13. O. Kretz, P. Barbry, R. Bock and B. Lindemann, Differential expression of RNA and protein of the three pore-forming subunits of the amiloride-sensitive epithelial sodium channel in taste buds of rat, J Histochem Cytochem 47 (1999), 51-64.
14. T. Matsukura and H. Tanaka, Applicability of zinc complex of L-carnosine for medical use, Biochemistry (Mosc) 65 (2000), 817-823. Review.
15. M. Ohki, Turnover of taste bud cells in rats with taste disorder caused by zinc deficiency, J Nihon Univ Med Assoc 49 (1990), 189-199.
16. A.S. Parasad and D. Oberleas, Ribonuclease and deoxyribonuclease activities in zinc-deficient tissues, J Lab Clin Med 83 (1974), 634-639.
17. P.J. Schechter, W.T. Friedwald, D.A. Bronzert, M.S. Raff and R.I. Henkin, Idiopathic hypogeusia: a description of the syndrome and a single-blind study with zinc sulfate, in: International Review of Neurobiology, C. Pfeiffer, ed., Academic Press, New York, 1972, pp. 125-140.
18. G.T. Wong, K.S. Gannon and R.F. Margolskee, Transduction of bitter taste and sweet taste by gustducin, Nature 381 (1996), 796-800.
19. C. Zhang, M. Cotter, A. Lawton, B. Oakley, L. Wong and Q. Zeng, Keratin 18 is associated with a subset of older taste cells in the rat, Differentiation 59 (1995), 155-162.