Effect of intravenous vasopressor on spread of spinal anaesthesia and fetal acid-base equilibrium

British Journal of Anaesthesia

Volumn 98, Issue 5, 2007, Pages 649-656

  Cooper, D W ^a   Gibb, S C ^a   Meek, T ^a   Owen, S ^a   Kokri, M S ^a   Malik, A T ^a   Koneti, K K ^a  

^a JAMES COOK UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

Acid base equilibrium, pH; Anaesthetic techniques, subarachnoid; Fetus; Sympathetic nervous system, ephedrine; Sympathetic nervous system, phenylephrine

Indexed keywords

BUPIVACAINE; DIAMORPHINE; EPHEDRINE; GLYCOPYRRONIUM BROMIDE; HYPERTENSIVE FACTOR; PHENYLEPHRINE; LOCAL ANESTHETIC AGENT; VASOCONSTRICTOR AGENT;

ADULT; APGAR SCORE; ARTICLE; BLOOD GAS; CESAREAN SECTION; CLINICAL TRIAL; COLD SENSATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG INFUSION; FEMALE; FETUS ACID BASE BALANCE; HUMAN; MONITORING; PH; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SPINAL ANESTHESIA; TOUCH; UMBILICAL ARTERY; ACID BASE BALANCE; ACIDOSIS; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; DRUG INTERACTION; FETOMATERNAL TRANSFUSION; FETUS; METABOLISM; METHODOLOGY; OBSTETRIC ANESTHESIA; PREGNANCY;

ACID-BASE EQUILIBRIUM; ACIDOSIS; ADULT; ANESTHESIA, OBSTETRICAL; ANESTHESIA, SPINAL; ANESTHETICS, LOCAL; BUPIVACAINE; CESAREAN SECTION; DOUBLE-BLIND METHOD; DRUG INTERACTIONS; EPHEDRINE; FEMALE; FETUS; HUMANS; MATERNAL-FETAL EXCHANGE; PHENYLEPHRINE; PREGNANCY; VASOCONSTRICTOR AGENTS;

EID: 34250346901     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aem056     Document Type: Article

References (13)

1. Cooper DW, Jeyaraj L, Hynd R, et al. Evidence that intravenous vasopressors can affect rostral spread of spinal anesthesia in pregnancy. Anesthesiology 2004; 101: 28-33
2. Riley ET. Editorial I: Spinal anaesthKsia for Caesarean delivery: keep the pressure up and don't spare the vasoconstrictors. Br J Anaesth 2004; 92: 459-61
3. Lee A, Ngan Kee WD, Gin T. A quantitative, systematic review of randomized controlled trials of ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean delivery. Anesth Analg 2002; 94: 920-6
4. Ngan Kee WD, Lau TK, Khaw KS, Lee BB. Comparison of metaraminol and ephedrine infusions for maintaining arterial pressure during spinal anesthesia for elective cesarean section. Anesthesiology 2001; 95: 307-13
5. Mercier FJ, Riley ET, Frederickson WL, Roger-Christoph S, Benhamou D, Cohen SE. Phenylephrine added to prophylactic ephedrine infusion during spinal anesthesia for elective cesarean section. Anesthesiology 2001; 95: 668-74
6. Cooper DW, Carpenter M, Mowbray P, Desira WR, Ryall DM, Kokri MS. Fetal and maternal effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery. Anesthesiology 2002; 97: 1582-90
7. Akerman N, Saxena S, Wilson R, Columb M, Lyons G, Effect of intrathecal diamorphine on block height during spinal anaesthesia for Caesarean section with bupivacaine, Br J Anaesth 2005; 94: 843-7
8. Russell IF. Levels of anaesthesia and intra-operative pain at Caesarean section under regional block. Int J Obstet Anesth 1995; 4: 71-7
9. Saravanan S, Robinson APC, Qayoum Dar A, Columb MO, Lyons GR. Minimum dose of intrathecal diamorphine required to prevent intraoperative supplementation of spinal anaesthesia for Caesarean section. Br J Anaesth 2003; 91: 368-72
10. Cooper DW, Mowbray P. Can choice of vasopressor therapy affect rostral spread of spinal anaesthetic? (letter) Anesthesiology 2003; 98 1524
11. Blumgart CH, Ryall D, Dennison B, Thompson-Hill LM. Mechanism of extension of spinal anaesthesia by extradural injection of local anaesthetic. Br J Anaesth 1992; 69: 457-60
12. Hocking G, Wildsmith JA. Intrathecal drug spread. Br J Anaesth 2004; 93: 568-78
13. Cooper DW, Gowni RR. Impact of changing from ephedrine to phenylephrine as the first-line vasopressor during urgent caesarean section. Int J Obstet Anesth 2006; 15: 339-40