Loss of AP-2α results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo

Oncogene

Volumn 26, Issue 28, 2007, Pages 4049-4058

  Schwartz, B ^a,b   Melnikova, V O ^a   Tellez, C ^a   Mourad Zeidan, A ^a   Blehm, K ^a   Zhao, Y J ^a   McCarty, M ^a   Adam, L ^a   Bar Eli, M ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

AP 2 ; Colon cancer; E cadherin; MMP 9; Transcriptional regulation

Indexed keywords

GELATINASE B; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR AP 2ALPHA; UNCLASSIFIED DRUG; UVOMORULIN; CADHERIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BINDING KINETICS; CANCER CELL; CANCER CELL CULTURE; CANCER INVASION; CELL INVASION; CHROMATIN IMMUNOPRECIPITATION; COLON CARCINOGENESIS; COLON CARCINOMA; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; REVIEW; RNA INTERFERENCE; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; ANIMAL; ARTICLE; COLON TUMOR; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE; UPREGULATION;

MAMMALIA; MUS MUSCULUS;

ANIMALS; CADHERINS; CELL LINE, TUMOR; COLONIC NEOPLASMS; DOWN-REGULATION; HUMANS; MATRIX METALLOPROTEINASE 9; MICE; MICE, NUDE; TRANSCRIPTION FACTOR AP-2; TRANSFECTION; UP-REGULATION;

EID: 34250341812     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210193     Document Type: Review

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